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Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
The price is CA $121 per night from Aug 10 to Aug 11
CA $121
CA $138 total
Aug 10 - Aug 11
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,004 reviews)
"Is an older building but not super old. The cleanliness and paint decor were top. This is the second time we have stayed and will do again."
Reviewed on Jul. 21, 2025

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from Aug 14 to Aug 15
CA $123
CA $142 total
Aug 14 - Aug 15
includes taxes & fees
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,005 reviews)
"Enjoyed everything"
Reviewed on Jul. 19, 2025

Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
The price is CA $110 per night from Jul 28 to Jul 29
CA $110
CA $126 total
Jul 28 - Jul 29
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,007 reviews)
Nice hotel.
"Very nice hotel. Very friendly and clean. Breakfast was good. Will stay here again when back in region."
Reviewed on Jul. 25, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Private Getaway on 270 Acres w/ Lake: Swim & Canoe
Marble Hill
Stay at this cabin in Advance. Enjoy hiking/biking on site, a pool table, and furnished patios.
9.8/10 Exceptional! (24 reviews)
Weekend Trip
"We really enjoyed our stay at the Happy Farm. They included so many amenities with no additional fee. The lake was amazing and we spent most of our weekend fishing and swimming. We will be back next year."
Reviewed on Jul. 7, 2025

The Blue Door
Oran
Enjoy free WiFi, laundry facilities, and patios.

Charming 3-bedroom house in delightful Advance with AC, WiFi
Advance
Book a stay at this family-friendly vacation home in Advance. Enjoy laundry facilities, an in-room coffeemaker, and air conditioning.
10/10 Exceptional! (4 reviews)
Reunion
"Lovely, clean home. Close to family for visit."
Reviewed on May 31, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.