
South Roxana Vacation Packages
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Your South Roxana Vacation
Come and experience this wonderful city for yourself with a South Roxana vacation package. Think about staying in the neighborhood of Old Jamestown, which is great for nature and walking, and your time here is sure to be unforgettable. Make your trip to South Roxana even more fun by including some sightseeing. Edwardsville Arts Center, Lewis and Clark Interpretive Center and National Great Rivers Museum are among the major attractions you'll want to explore. Your South Roxana vacation is clicks away. Search accommodations, flights and more on Expedia for a trip that's tailored just for you.
Top South Roxana Vacation Deals

The Wildwood Hotel
Reviewed on Jul 13, 2026


The Cheshire
Reviewed on Jul 12, 2026

Hilton Garden Inn Chesterfield
Reviewed on Jul 7, 2026

Ameristar Casino Resort and Spa
Reviewed on Jul 13, 2026
South Roxana Hotel Deals

Hyatt Regency St. Louis at The Arch
"So perfectly located to all downtown attractions."
Reviewed on Jul 13, 2026

Clayton Plaza Hotel & Extended Stay
"We had a string of negative experiences during our three-night stay. The first night, the air conditioner in the room was rattling very loudly. I called the front desk and they seemed very annoyed to be talking to me, but they offered to get us a new room. The keys they gave us for the new room didn't ..."
Reviewed on Jul 13, 2026

Pear Tree Inn St. Louis Airport
"Overall the hotel was very clean. Staff were friendly. Breakfast was average. Very close to the airport, but did not hear the air traffic. Our room was spotless!"
Reviewed on Jul 13, 2026







