Title: Book The Best Hotels in São Tomé for 2026 from CA $22 - Fully Refundable Options - Expedia.ca

[Vacation Rentals in São Tomé](https://expedia.ca/Sao-Tome-Vacation-Rentals.d553248634664607275.Travel-Guide-VacationRentals)[São Tomé Car Rentals](https://expedia.ca/Car-Rentals-In-Sao-Tome.d553248634664607275.Car-Rental-Guide)[São Tomé Vacation Packages](https://expedia.ca/Sao-Tome.d553248634664607275.Destination-Travel-Guides)

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## Check prices for these dates

Tonight

[Mar 18 - Mar 19](https://www.expedia.ca/Hotel-Search?regionId=553248634664607275&startDate=2026-03-18&endDate=2026-03-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 19 - Mar 20](https://www.expedia.ca/Hotel-Search?regionId=553248634664607275&startDate=2026-03-19&endDate=2026-03-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=553248634664607275&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=553248634664607275&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for São Tomé hotels

![Property grounds](https://images.trvl-media.com/lodging/121000000/120090000/120088600/120088564/9c18310e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, Garden View](https://images.trvl-media.com/lodging/121000000/120090000/120088600/120088564/w904h1595x0y0-12a9ad3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120090000/120088600/120088564/f17f2ee3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/121000000/120090000/120088600/120088564/9e74873b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pousada Santo Mel

[](https://www.expedia.ca/Sao-Tome-Hotels-Pousada-Santo-Mel.h120088564.Hotel-Information)

São Tomé

CA $21

CA $22 total

includes taxes & fees

Mar 31 - Apr 1

[](https://www.expedia.ca/Sao-Tome-Hotels-Pousada-Santo-Mel.h120088564.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/125000000/124870000/124860900/124860872/3968a245_edited_841e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gift shop](https://images.trvl-media.com/lodging/125000000/124870000/124860900/124860872/f0af28a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free parking nearby](https://images.trvl-media.com/lodging/125000000/124870000/124860900/124860872/e65f3d99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Single Room, City View](https://images.trvl-media.com/lodging/125000000/124870000/124860900/124860872/6e32dbea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Imperial

[](https://www.expedia.ca/Santa-Cruz-Hotels-Hotel-Imperial.h124860872.Hotel-Information)

Santa Cruz

CA $51

CA $54 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/Santa-Cruz-Hotels-Hotel-Imperial.h124860872.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top São Tomé Hotel Reviews

## More cheap stays in São Tomé

![Pousada Santo Mel](https://images.trvl-media.com/lodging/121000000/120090000/120088600/120088564/6a8d3aff_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Pousada Santo Mel

R. Jose Lopes Pereira São Tomé RN

CA $21

CA $22 total

Mar 31 - Apr 1

includes taxes & fees

[](https://expedia.ca/Sao-Tome-Hotels-Pousada-Santo-Mel.h120088564.Hotel-Information)

## Frequently asked questions

### What's the best place for a stay in São Tomé?

### If I need to cancel my hotel reservation in São Tomé, will I receive a refund?

### How is it to stay in São Tomé?

### What should I do while I'm visiting São Tomé?

### What's the weather like in São Tomé?

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