Santa Cruz Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Santa Cruz

Price found within the past 48 hours. Click for updated prices.
H10 Corregidor Boutique Hotel
Hotel Vincci Molviedro Suites Apartments
Hotel Gravina 51
Eurostars Al-Ándalus Palace
Eurostars Guadalquivir

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz

Santa Cruz Hotel Deals

Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
Fully refundableReserve now, pay when you stay
The price is CA $129 per night from Jun 7 to Jun 8
CA $129
CA $142 total
Jun 7 - Jun 8
includes taxes & fees
8.8/10 Excellent! (1,026 reviews)
Breakfast selection was excellent & great location Room was really old and dated - grubby bathroom with grime around the shower floor Room was next to the lift so we had a constant stream of people standing outside our room talking and the lift going up and down Overlooked the air conditioning units ...

Reviewed on May 9, 2026

Hotel Murillo
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
The price is CA $233 per night from Jun 7 to Jun 8
CA $233
CA $257 total
Jun 7 - Jun 8
includes taxes & fees
9.4/10 Exceptional! (1,006 reviews)
Pedro was very helpful and went out of his way to make sure we had everything we needed. The only downside to the stay was the breakfast. It was $20 approx per person, to find out after we had the buffet food, that we could have ordered from a menu. Besides that, it was a lovely stay.

Reviewed on May 8, 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
Fully refundableReserve now, pay when you stay
The price is CA $234 per night from Jun 1 to Jun 2
CA $234
CA $257 total
Jun 1 - Jun 2
includes taxes & fees
9.6/10 Exceptional! (1,204 reviews)
Riad style hotel with interlinked g/f seating areas beautifully decorated along the classical music theme with piped classical music, books of sheet music, portraits of classical composers and a myriad of musical instruments. Intimate breakfast areas with small tables and a fixed meal to set you ...

Reviewed on May 10, 2026

Hotel Amadeus Sevilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz vacation package cost?
Get ready to book, because a trip to Santa Cruz starts from a tempting CA $1,537. When you combine your hotels, flights and car rentals into a package, you'll enjoy the biggest deals.
How do I get a cheap travel package to Santa Cruz?
Just think of all the fun things you could do in Santa Cruz with a pile of extra cash in your pocket. Watch your savings stack up when you combine your travel bookings into a Santa Cruz vacation package. You have plenty of choice when it comes to booking with Expedia too. In fact, you can select from over 550 airlines and 1,000,000 properties around the world. Whether you're enjoying a break with the whole family or traveling with someone special, exploring Santa Cruz is better with a package.
Where should I stay in Santa Cruz?
Most people who visit Santa Cruz put both Seville Cathedral and Alcázar on their must-see lists. Why not choose a hotel close to one of these iconic attractions?
What are the top hotels in Santa Cruz?
Puerta Catedral Holiday Suites and San Isidoro Hostel Sevilla are among the most well-known properties in Santa Cruz. Why not check out the rates and facilities at each and then make up your mind?
How far in advance should I book my Santa Cruz vacation?
Reserving your seat early with Expedia means one less thing to have to worry about. Most carriers advertise prices up to 12 months prior to take off. This is generally the cheapest time to book. If circumstances have left you booking late, great deals to Santa Cruz sometimes emerge in the weeks leading up to departure.
What does an Expedia Santa Cruz travel package include?
Hotels, car rentals and flights — we bring you the very best deals. All you'll have to do is decide on your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and tours. Our travel packages make it easy to craft an awesome Santa Cruz trip.
What should I know before booking a Santa Cruz travel package?
You'll pick up impressive savings when you bundle your flights, hotels and rental cars into a package. Plus, booking everything in one place just makes things easier. So why waste your time or money? Whether you're putting together an upscale romantic escape or a budget family adventure, explore our vacation packages today.
Can I choose my airline with a Santa Cruz Expedia vacation package?
Yes — that's the beauty of an Expedia package. You're in control. We have more than 550 airline partners around the world, so you have loads of choice when organizing your Santa Cruz getaway.
If I'm not able to travel, can I cancel my Santa Cruz vacation package?
Yes, it's possible to cancel your Santa Cruz booking if your travel plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. You may be able to change or cancel for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.