Title: Visit Santa Cruz de la Sierra: Best of Santa Cruz de la Sierra Tourism | Expedia Travel Guide - Expedia.ca

[Hotels in Santa Cruz de la Sierra](https://expedia.ca/Santa-Cruz-De-La-Sierra-Hotels.d6356838.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz de la Sierra](https://expedia.ca/Santa-Cruz-De-La-Sierra-Vacation-Rentals.d6356838.Travel-Guide-VacationRentals)[Santa Cruz de la Sierra Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz-De-La-Sierra.d6356838.Car-Rental-Guide)[Santa Cruz de la Sierra Vacation Packages](https://expedia.ca/Santa-Cruz-De-La-Sierra.d6356838.Destination-Travel-Guides)

# Santa Cruz de la Sierra

## Travel Guide

![Catedral de Santa Cruz de la Sierra](https://images.trvl-media.com/place/6356838/d51eab97-c49d-4664-b787-8b19a64ced01.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Catedral de Santa Cruz de la Sierra](https://images.trvl-media.com/place/6356838/d51eab97-c49d-4664-b787-8b19a64ced01.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

## Visit Santa Cruz de la Sierra

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Vacation Sale 

Members save up to 40% on hotels and homes. Plan this year’s big trip and save. 

[Book now](https://expedia.ca/deals?rfrr=DX_SPRING_PROMO_6356838)

- Santa Cruz de la Sierra Hotel Deals
- Vacation Rentals in Santa Cruz de la Sierra

![Rural house (full rental) El Olivar del Marqués for 26 people](https://images.trvl-media.com/lodging/33000000/32870000/32866900/32866897/81656d8a_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Rural house (full rental) El Olivar del Marqués for 26 people

 Santa Cruz de la Sierra Cáceres

Stay at this cottage in Santa Cruz de la Sierra. Enjoy a garden, laundry facilities, and a pool table.

[Get rates](https://expedia.ca/Hotel-Search?startDate=14%2F03%2F2026&endDate=15%2F03%2F2026&selected=32866897&PinnedHotelID=32866897&HadPinnedHotel=true&regionId=6356838)

[](https://expedia.ca/Hotel-Search?startDate=14%2F03%2F2026&endDate=15%2F03%2F2026&selected=32866897&PinnedHotelID=32866897&HadPinnedHotel=true&regionId=6356838)

![Parador de Trujillo](https://images.trvl-media.com/lodging/2000000/1140000/1134900/1134802/2e2ba893_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Parador de Trujillo

Santa Beatriz de Silva 1 Trujillo Caceres

CA $105

CA $116 total

Mar 16 - Mar 17

includes taxes & fees

Book a stay at this business-friendly hotel in Trujillo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Popular attractions Palace of the Dukes ...

9.2/10 Wonderful! (225 reviews)

Very nice hotel, good parking, well located,

Reviewed on Nov 18, 2025

[](https://expedia.ca/Hotel-Search?startDate=16%2F03%2F2026&endDate=17%2F03%2F2026&selected=1134802&PinnedHotelID=1134802&HadPinnedHotel=true&regionId=6356838)

![Eurostars Palacio Santa Marta](https://images.trvl-media.com/lodging/2000000/1150000/1142400/1142399/ced9ce40_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Eurostars Palacio Santa Marta

Calle Ballesteros 6 Trujillo Caceres

CA $95

CA $105 total

Mar 15 - Mar 16

includes taxes & fees

Book a stay at this business-friendly hotel in Trujillo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in ...

9.2/10 Wonderful! (332 reviews)

This hotel is absolutely fabulous! Highly recommend!!!! It is an old palace, our room was spacious, beds comfortable, beautiful views, location is perfect! The staff is friendly and professional. If I ever come to Trujillo again I will certainly stay here!

Reviewed on Jan 8, 2026

[](https://expedia.ca/Hotel-Search?startDate=15%2F03%2F2026&endDate=16%2F03%2F2026&selected=1142399&PinnedHotelID=1142399&HadPinnedHotel=true&regionId=6356838)

[See all 83 properties in Santa Cruz de la Sierra](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=01%2F03%2F2026&endDate=02%2F03%2F2026&regionId=6356838)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![Rural house (full rental) El Olivar del Marqués for 26 people](https://images.trvl-media.com/lodging/33000000/32870000/32866900/32866897/81656d8a_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Rural house (full rental) El Olivar del Marqués for 26 people

 Santa Cruz de la Sierra Cáceres

Stay at this cottage in Santa Cruz de la Sierra. Enjoy a garden, laundry facilities, and a pool table.

[](https://expedia.ca/Santa-Cruz-De-La-Sierra-Hotels-Rural-House.h32866897.Hotel-Information)

![Charming spacious barn in beautiful tranquil scenery, pool on property](https://images.trvl-media.com/lodging/33000000/32650000/32647100/32647019/a6397645_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Charming spacious barn in beautiful tranquil scenery, pool on property

 Albalá del Caudillo EX

Stay at this cottage in Albalá. Enjoy free WiFi, private pools, and a garden.

9.6/10 Exceptional! (14 reviews)

Great property, great location, great hosts

Hosts welcomed me on arrival, gave me some pointers on dealing with the August heat as well as things to see and do in the area.

Reviewed on Sep 4, 2024

[](https://expedia.ca/Albala-Hotels-Charming-Spacious-Barn-With-Swimming-Pool-In-Beautiful-Tranquil-Scenery.h32647019.Hotel-Information)

![APARTAMENTOS VIVE TRUJILLO](https://images.trvl-media.com/lodging/107000000/106010000/106009400/106009372/1613468c_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

APARTAMENTOS VIVE TRUJILLO

C. Arquillo 13 Trujillo Cáceres

Stay at this apartment in Trujillo. Enjoy free WiFi. Popular attractions Juan Pizarro de Orellana Palace and Palacio de la Conquista are located nearby.

[](https://expedia.ca/Trujillo-Hotels-APARTAMENTOS-VIVE-TRUJILLO.h106009372.Hotel-Information)

[See all properties in Santa Cruz de la Sierra](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&regionId=6356838&sort=VACATION_RENTAL)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Check Santa Cruz de la Sierra hotel availability

[Tonight

](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6356838&startDate=2026-02-28&endDate=2026-03-01)[Feb 28 - Mar 1](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6356838&startDate=2026-02-28&endDate=2026-03-01)

[Tomorrow night

](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6356838&startDate=2026-03-01&endDate=2026-02-02)[Mar 1 - Mar 2](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6356838&startDate=2026-03-01&endDate=2026-02-02)

[Next weekend

](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6356838&startDate=06%2F03%2F2026&endDate=08%2F03%2F2026)[Mar 6 - Mar 8](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6356838&startDate=06%2F03%2F2026&endDate=08%2F03%2F2026)

## Cities near Santa Cruz de la Sierra

![view from alcazaba](https://images.trvl-media.com/place/181342/0f223821-d4aa-4ee4-9ab4-c66f89ad11b2.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Trujillo

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- [Car rental Cáceres ](https://www.expedia.ca/Car-Rentals-In-Caceres.d5120.Car-Rental-Guide)
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- [Things to do in Guadalupe ](https://www.expedia.ca/Things-To-Do-In-Guadalupe.d6035111.Travel-Guide-Activities)

- Cities near Santa Cruz de la Sierra
- Places of interest

[Trujillo](https://expedia.ca/Trujillo.dx181342)

- [Palacio de la Conquista ](https://expedia.ca/Palacio-De-La-Conquista-Trujillo.d553248621533072006.Vacation-Attraction)

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