Downtown Clayton

St. Louis

Downtown Clayton

Popular places to visit

Things to do


Downtown Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is CA $135 per night from May 17 to May 18
CA $135
CA $158 total
May 17 - May 18
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,189 reviews)
Excellent breakfast Receptionist not too friendly

Reviewed on May 6, 2026

Clayton Plaza Hotel & Extended Stay
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
The price is CA $679 per night from May 10 to May 11
CA $679
CA $793 total
May 10 - May 11
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the room ...
9.2/10 Wonderful! (566 reviews)
When we arrived it was really loud hard to hear customer service as karaoke was going on.

Reviewed on Apr 27, 2026

The Ritz-Carlton, St. Louis
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
The price is CA $196 per night from May 17 to May 18
CA $196
CA $229 total
May 17 - May 18
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
9/10 Wonderful! (300 reviews)
Use public parking lot next door, cheaper than valet

Reviewed on May 5, 2026

AC Hotel St. Louis Clayton
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
The price is CA $196 per night from May 24 to May 25
CA $196
CA $230 total
May 24 - May 25
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (712 reviews)
It was good but there is just one problem of parking and they charge for patking 35 bucks

Reviewed on Apr 28, 2026

Le Méridien St. Louis Clayton
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is CA $172 per night from May 25 to May 26
CA $172
CA $203 total
May 25 - May 26
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,054 reviews)
Great location next to the arc. Clean and courteous staff.

Reviewed on May 6, 2026

Hyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is CA $196 per night from Jun 7 to Jun 8
CA $196
CA $235 total
Jun 7 - Jun 8
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,820 reviews)
Really cool hotel with great onsite bar/restaurant, gym, pool and art gallery.

Reviewed on May 6, 2026

21C Museum Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown Clayton

St. Louis Missouri

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Clayton
University City

University City

Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Heman Park Tennis Center are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.

University City
View of St. Louis and the historic Gateway Arch in Missouri, from across the Mississippi River in Malcolm W. Martin Memorial Park, Illinois

Ladue

The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and St. Louis Zoo, a few notable attractions nearby.

Ladue
The bandstand located in Forest Park, St. Louis, Missouri.

Dogtown

If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.

Dogtown
Visitor Center in Forest Park in St. Louis

The Hill

If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Zoo and St. Louis Science Center.

The Hill
Central West End

Central West End

4/5(6 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End


Downtown Clayton

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