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Oct 8 - Oct 9
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Oct 9 - Oct 10
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Oct 9 - Oct 11
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Our top choices for Pamplico hotels

An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.
A spacious bar area with a wooden floor, multiple bar stools, and a variety of bottles on shelves.
A spacious living room with hardwood flooring, a staircase, and a large window.
A spacious lobby with a grand staircase, plush seating, and a modern kitchen area.

1. The Inn at the Crossroads

The Inn at the Crossroads
Lake City
United States
Paige
CA $159
CA $178 total
includes taxes & fees
Nov 8 - Nov 9
The Inn at the Crossroads
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

2. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
United States
Windia
CA $127
CA $142 total
includes taxes & fees
Oct 25 - Oct 26
Park Inn by Radisson Florence, SC
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

3. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
United States
Shanti
CA $143
CA $160 total
includes taxes & fees
Nov 2 - Nov 3
Hyatt Place Florence Downtown
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.
A two-story building with a brick facade, a flat roof, and a covered entrance area.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

4. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
Florence
United States
HOMERO
CA $92
CA $103 total
includes taxes & fees
Oct 25 - Oct 26
Howard Johnson by Wyndham Florence
A spacious lobby with a chandelier, seating area, and a reception desk.
A hotel room with a bed, a sofa, a desk, and a chair.
A hotel entrance with a covered walkway, palm trees, and a clear sky.
A spacious lobby with a chandelier, sofas, a reception desk, and a large window.

5. Quality Inn & Suites Lake City

Quality Inn & Suites Lake City
Lake City
United States
Vajannise
CA $149
CA $167 total
includes taxes & fees
Nov 8 - Nov 9
Quality Inn & Suites Lake City
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

6. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
United States
Mila
CA $144
CA $161 total
includes taxes & fees
Nov 4 - Nov 5
Comfort Inn & Suites Florence Center Area
A spacious lobby with a large seating area, a decorative ceiling light, and a view of the outdoors.
A hotel room with two beds, a desk, a chair, and a sofa.
A hotel reception area with a counter, a 'Days Inn Lake City' award plaque, and a 'Jazmin' sign.
A brick building with a stone pillar, large potted plants, and a wreath on the door.

7. Days Inn by Wyndham Lake City

Days Inn by Wyndham Lake City
Lake City
United States
Emma
CA $141
CA $157 total
includes taxes & fees
Oct 20 - Oct 21
Days Inn by Wyndham Lake City
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.
A breakfast buffet with a variety of food items, including pastries and cereal boxes, and a sign indicating the availability of cinnamon sweet rolls.
A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."

8. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
Florence
United States
Christopher
CA $174
CA $209 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A hotel room with a desk, chair, bed, and a yellow sofa.
A swimming pool with lounge chairs and a building with balconies.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.

9. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
Florence
Canada
Noémie
CA $126
CA $141 total
includes taxes & fees
Oct 18 - Oct 19
Quality Inn & Suites Florence Civic Center
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.
A hotel room with a bed, sofa, TV, and a desk.
A La Quinta Inn & Suites hotel with a modern facade, a well-lit entrance, and a landscaped garden area.
A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.

10. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
Florence
United States
Heather
CA $122
CA $136 total
includes taxes & fees
Oct 25 - Oct 26
La Quinta Inn & Suites by Wyndham Florence
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.
A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

11. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
Florence
United States
Tienia
CA $120
CA $140 total
includes taxes & fees
Oct 25 - Oct 26
Spark by Hilton Florence North I-95, SC
A restaurant with brick walls, framed awards, and a bar area.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.
A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.
A bar area with a curved counter, multiple stools, and a brick wall backdrop.

12. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
Florence
United States
Ankh
CA $171
CA $191 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Florence, Tapestry Collection by Hilton
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.
A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

13. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
Florence
United States
Tiffany
CA $144
CA $169 total
includes taxes & fees
Oct 25 - Oct 26
Tru by Hilton Florence I-95
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.
A hotel lobby with a reception desk, seating area, and a welcome mat.
A lobby with a fireplace, seating area, and a television.

14. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence
United States
Ryan
CA $162
CA $182 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn & Suites Florence Center
A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.
An indoor swimming pool with clear blue water, surrounded by green chairs and a tiled floor.
A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.
Property amenity

15. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
Florence
United States
John
CA $132
CA $156 total
includes taxes & fees
Oct 25 - Oct 26
SpringHill Suites by Marriott Florence
A hotel with a modern design, multiple floors, and a parking lot.
A reception area with a Best Western sign, a reception desk, a waiting area with a blue patterned sofa, and a potted plant.
A restaurant with a bar area, seating, and a kitchen visible in the background.
A hotel room with a checkered sofa, a bed, a desk, and a framed picture on the wall.

16. Best Western Inn

Best Western Inn
Florence
United States
Steward Heikes
CA $126
CA $142 total
includes taxes & fees
Nov 4 - Nov 5
Best Western Inn
A hotel entrance with a stone facade, glass doors, and a number '501' above.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

17. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
Florence
United States
Alma
CA $168
CA $188 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield Inn & Suites by Marriott Florence I-20
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A breakfast setup with a flat-screen TV displaying a breakfast menu, a flat-screen TV, a coffee machine, and a tray of pancakes.
A reception area with a modern design, featuring a reception desk, a digital display, and a sign for Holiday Inn Express & Suites.
A coffee station with two coffee machines and a display of coffee pods and cups.

18. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Florence
United States
Leigh
CA $163
CA $182 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.
A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.

19. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
Florence
United States
Crystal
CA $156
CA $175 total
includes taxes & fees
Nov 2 - Nov 3
TownePlace Suites by Marriott Florence
A hotel with a covered entrance, a beige facade, and pink flowering trees.
A hotel lobby with a reception desk, a wall-mounted TV, a decorative wall piece, and a seating area with tables and chairs.
A living room with a sofa, a coffee table, a chair, and two framed floral paintings on the wall.
A breakfast buffet with multiple serving dishes and a coffee station by a window with a view of trees.

20. Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
Marion
United States
Jasmine
CA $110
CA $120 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Mullins - Marion
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Top Pamplico Hotel Reviews

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

8/10 Good
"The location was convenient and the hotel was quiet. Unfortunately, the room was quite light all night long. The window had black-out curtains, but they were only a bit longer than the height of the window AND were hung eight inches away from the glass so the very bright parking lot lights illuminated the entire room. Do not get me wrong, I was happy that the manager was concerned about parking security, however, I would have enjoyed a darker setting for sleep. The staff was very polite. The facility was clean."
Tim 1-night trip
Posted less than an hour ago
Howard Johnson by Wyndham Florence
Best Western Executive Inn

Best Western Executive Inn

10/10 Excellent
"Not necessarily unique property. However, the staff were so kind!! We would stay here again for sure! Thank you ladies - from desk to housekeeping!!"
Irvin 2-night trip
Posted 4 hours ago
Best Western Executive Inn
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

8/10 Good
"Nothing to say"
jun 1-night trip
Posted 13 hours ago
Comfort Inn & Suites Florence Center Area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

10/10 Excellent
"Spark always has clean hotels and comfortable beds, this location was no different. Enjoyed our stay"
Kelly 1-night trip
Posted 1 day ago
Spark by Hilton Florence North I-95, SC
Comfort Suites Florence I-95

Comfort Suites Florence I-95

10/10 Excellent
"Excellent!!"
Monique J. 2-night trip
Posted 3 days ago
Comfort Suites Florence I-95
Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

10/10 Excellent
"Excelente lugar"
Edgar 3-night trip
Posted 3 days ago
Super 8 by Wyndham Florence
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

10/10 Excellent
"Room clean. Staff was courteous and professional. Great location."
Ellen 1-night trip
Posted 7 days ago
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

More cheap stays in Pamplico

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
CA $92
CA $103 total
Oct 25 - Oct 26
includes taxes & fees
8.6/10 Excellent! (2,737 reviews)
Howard Johnson by Wyndham Florence
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence SC
CA $92
CA $103 total
Oct 15 - Oct 16
includes taxes & fees
Days Inn by Wyndham Florence Near Civic Center
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC
CA $126
CA $141 total
Oct 18 - Oct 19
includes taxes & fees
Quality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC
CA $127
CA $142 total
Oct 25 - Oct 26
includes taxes & fees
Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC
CA $144
CA $161 total
Nov 4 - Nov 5
includes taxes & fees
9/10 Wonderful! (1,366 reviews)
Comfort Inn & Suites Florence Center Area
The Inn at the Crossroads

The Inn at the Crossroads

128 West Main Street Lake City SC
CA $159
CA $178 total
Nov 8 - Nov 9
includes taxes & fees
The Inn at the Crossroads

Hotels in Pamplico with star rating

Frequently asked questions

What is the best area to stay in Pamplico?
The best area to stay in Pamplico is within the town centre itself, particularly around Main Street.This area is the heart of Pamplico, offering the most convenience for visitors. Main Street is where you'll find the majority of local businesses, including small shops and eateries, and it's easily navigable on foot. The town's historic charm is evident in the architecture of the older buildings lining the street.For solo travellers or couples, staying within the town centre provides easy access to local life and amenities. You'll be able to stroll to local cafes for breakfast or explore the few boutique shops without needing a car.
When is the best time to go to Pamplico?
The best time to visit Pamplico, South Carolina, is during the spring (April to May) and autumn (September to October) months.These seasons offer pleasant weather conditions, with comfortable temperatures and lower humidity compared to the summer. This makes it ideal for enjoying outdoor activities and exploring the local area without the intense heat.For those interested in local agricultural events and the natural beauty of the Pee Dee Region, these periods often coincide with local festivals and the blooming or changing colours of the landscape.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Pamplico.
How much is the nightly rate at a Pamplico hotel?
Prices for hotels in Pamplico often vary, but you can find a great deal from CA $87 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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