Title: Book The Best Hotels in Pamplico, SC for 2026 from CA $77 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Pamplico](https://expedia.ca/Pamplico-Vacation-Rentals.d3000353197.Travel-Guide-VacationRentals)[Things to do in Pamplico](https://expedia.ca/Things-To-Do-In-Pamplico.d3000353197.Travel-Guide-Activities)[Pamplico Car Rentals](https://expedia.ca/Car-Rentals-In-Pamplico.d3000353197.Car-Rental-Guide)[Pamplico Vacation Packages](https://expedia.ca/Pamplico.d3000353197.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Pamplico Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&amenities=PETS) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&amenities=HOT_TUB) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&lodging=COTTAGE) ## Check prices for these dates Tonight [Feb 15 - Feb 16](https://www.expedia.ca/Hotel-Search?regionId=3000353197&startDate=2026-02-15&endDate=2026-02-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 16 - Feb 17](https://www.expedia.ca/Hotel-Search?regionId=3000353197&startDate=2026-02-16&endDate=2026-02-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=3000353197&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=3000353197&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Pamplico hotels ![Exterior](https://images.trvl-media.com/lodging/119000000/118990000/118982900/118982850/8e3233ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Florence Downtown [](https://www.expedia.ca/Florence-Hotels-Rodeway-Inn.h118982850.Hotel-Information) Florence 6.0/10 (2 reviews) "Good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joshua CA $67 CA $77 total includes taxes & fees Mar 16 - Mar 17 [](https://www.expedia.ca/Florence-Hotels-Rodeway-Inn.h118982850.Hotel-Information) ![Desk, laptop workspace, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/868ff462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/6673044c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/8d075bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/ada13811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Florence - Civic Center [](https://www.expedia.ca/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) Florence 6.8/10 (1,001 reviews) "Room was good. No microwave tho. Staff was very courteous and helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $76 CA $85 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/6ea04fee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/801b8be0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/d32e89e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite | Private kitchen](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/bca415cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Affordable Suites Florence [](https://www.expedia.ca/Florence-Hotels-Affordable-Suites-Florence.h57719723.Hotel-Information) Florence 9.2/10 Wonderful (137 reviews) "Nice clean room; friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angelo [](https://www.expedia.ca/Florence-Hotels-Affordable-Suites-Florence.h57719723.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/25cb76ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/2132b0fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/bdaaa724.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/c42cf41b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Florence North I-95, SC [](https://www.expedia.ca/Florence-Hotels-Spark-By-Hilton-Florence-North-I-95.h42602.Hotel-Information) Florence 8.0/10 Very good (47 reviews) "Wonderful staff and very clean room and facilities , " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) catherine CA $101 CA $119 total includes taxes & fees Feb 24 - Feb 25 [](https://www.expedia.ca/Florence-Hotels-Spark-By-Hilton-Florence-North-I-95.h42602.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/20f68e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/d5b1a48f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/5b7b6acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Florence I-95 [](https://www.expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) Florence 8.4/10 Very good (1,000 reviews) "We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marita CA $127 CA $147 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/68000000/67640000/67630500/67630478/c4d8b560.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/68000000/67640000/67630500/67630478/f96d3fd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/68000000/67640000/67630500/67630478/508d2b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/68000000/67640000/67630500/67630478/827b0dc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Florence , SC [](https://www.expedia.ca/Florence-Hotels-Studio-6-Florence.h67630478.Hotel-Information) Florence 3.2/10 (5 reviews) "It was a real dive, not actually a hotel. Our room was in a shambles, not just dirty. The only good thing was that we were refunded and we left as quickly as possible. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller CA $75 CA $84 total includes taxes & fees Feb 20 - Feb 21 [](https://www.expedia.ca/Florence-Hotels-Studio-6-Florence.h67630478.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/e08b1bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/c76a36a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/7c55894f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/de3f1188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Marriott Florence [](https://www.expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) Florence 8.8/10 Excellent (513 reviews) "Clean room, great location, easy check-in & check-out, friendly service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shaun CA $135 CA $151 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/87bb3ed5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/078b0644.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/ebe19db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/098e0775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Florence SC I-95 North / Hwy 76 [](https://www.expedia.ca/Florence-Hotels-Travelodge-By-Wyndham-Florence.h528148.Hotel-Information) Florence 5.2/10 (352 reviews) "Room was average. Breakfast was a joke, no name cereal and coffee " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Waleed CA $71 CA $80 total includes taxes & fees Feb 16 - Feb 17 [](https://www.expedia.ca/Florence-Hotels-Travelodge-By-Wyndham-Florence.h528148.Hotel-Information) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/2aa0d516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/4a7dfdb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Single Room (327503716)](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/d9531705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/fb249555.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Florence Inn and Suites [](https://www.expedia.ca/Florence-Hotels-Florence-Inn-And-Suites.h20253.Hotel-Information) Florence 6.4/10 (331 reviews) "Parking was good " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $89 CA $100 total includes taxes & fees Feb 19 - Feb 20 [](https://www.expedia.ca/Florence-Hotels-Florence-Inn-And-Suites.h20253.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/3ba2ede7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/1a4a47d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/d6de6ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence/I-95 North [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) Florence 6.8/10 (1,006 reviews) "Great room and reasonable price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hattab CA $81 CA $91 total includes taxes & fees Feb 20 - Feb 21 [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Premium bedding, pillowtop beds, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/1000000/10000/500/455/ef1db617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/455/af3985b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/500/455/344e3fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/500/455/5074ad24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Inn [](https://www.expedia.ca/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) Florence 7.8/10 Good (1,001 reviews) "Front desk staff was great and very friendly! Made for a smooth check-in!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patric CA $121 CA $136 total includes taxes & fees Feb 16 - Feb 17 [](https://www.expedia.ca/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/75000000/74430000/74425300/74425295/c1c00c42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/75000000/74430000/74425300/74425295/bae8a99a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/75000000/74430000/74425300/74425295/7d45f85e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/75000000/74430000/74425300/74425295/861333a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites Florence - Darlington [](https://www.expedia.ca/Florence-Hotels-MainStay-Suites.h74425295.Hotel-Information) Florence 3.6/10 (79 reviews) "It was absolutely amazing I would recommend 1000%" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Destiny CA $103 CA $115 total includes taxes & fees Mar 17 - Mar 18 [](https://www.expedia.ca/Florence-Hotels-MainStay-Suites.h74425295.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/89338f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/1aa3f791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/042032ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, Tempur-Pedic beds, in-room safe, desk](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/861e9f4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Florence - Civic Center by IHG [](https://www.expedia.ca/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) Florence 9.4/10 Exceptional (958 reviews) "Room clean, bed good, breakfast good choices, front desk excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mona CA $195 CA $218 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/88f4ba4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/ee878326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/f287bfc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence Center [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) Florence 9.0/10 Wonderful (855 reviews) "Staff was very kind and conscious of our needs" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $150 CA $168 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/ddbd2495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/68010423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/825507c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/8b770330.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Florence [](https://www.expedia.ca/Florence-Hotels-Hilton-Garden-Inn-Florence.h1367205.Hotel-Information) Florence 8.6/10 Excellent (282 reviews) "The hotel is very pet friendly. Close to stores and restaurants. Clean, friendly, for is great in the restaurant in the hotel as well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $155 CA $174 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Florence-Hotels-Hilton-Garden-Inn-Florence.h1367205.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/c68ab7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/d963a865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/5054dc3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/67a43c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Florence I-95 [](https://www.expedia.ca/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) Florence 8.4/10 Very good (1,002 reviews) "Great accommodations and courteous staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie CA $127 CA $147 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/61200/61124/b48e59d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/61200/61124/186dc725.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/61200/61124/e38041eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/70000/61200/61124/1a8b8b2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Florence North [](https://www.expedia.ca/Florence-Hotels-Sleep-Inn-Florence.h61124.Hotel-Information) Florence 7.4/10 Good (694 reviews) "Staff was courteous and the room was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank CA $93 CA $104 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Florence-Hotels-Sleep-Inn-Florence.h61124.Hotel-Information) ![Iron/ironing board, rollaway beds, bed sheets](https://images.trvl-media.com/lodging/1000000/190000/180100/180086/19a81874.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/190000/180100/180086/3252d1d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/190000/180100/180086/ab8d3cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/190000/180100/180086/64acc9c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Florence - Darlington [](https://www.expedia.ca/Florence-Hotels-Econo-Lodge.h180086.Hotel-Information) Florence 5.8/10 (1,000 reviews) "Nasty" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brazlyn CA $71 CA $80 total includes taxes & fees Feb 16 - Feb 17 [](https://www.expedia.ca/Florence-Hotels-Econo-Lodge.h180086.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/f82666ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/852cfc33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/dc8d999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center [](https://www.expedia.ca/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) Florence 7.8/10 Good (1,265 reviews) "Quiet clean and many options local for food etc Good for a night or two stay Bed was comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Louis CA $115 CA $129 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/bac50e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d1f8ba02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d2976b97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence Near Civic Center [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) Florence 6.8/10 (1,002 reviews) "Love this room dearly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andre CA $90 CA $101 total includes taxes & fees Feb 16 - Feb 17 [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-01&endDate=2026-03-02®ionId=3000353197&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=HTG_SPRING_PROMO_3000353197) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPamplico-Hotels.d3000353197.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPamplico-Hotels.d3000353197.Travel-Guide-Hotels) ## Top Pamplico Hotel Reviews ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent "The room was clean and check in was quick. We booked the room for 4 adults but the bathroom was only stocked with 2 sets of towels and washcloths. This was remedied within 5 minutes of notifying the front desk. Breakfast was good just your typical items to choose from. All in all we were pleased with our stay and would stay here again if needed. " [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg) ### La Quinta Inn & Suites by Wyndham Florence 10/10 Excellent "ye" [](https://expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "Very clean. The staff was so friendly and helpful. The breakfast was great!!! I’ll definitely be back " [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/17df73d5_y.jpg) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG 10/10 Excellent "Room was spotless!!" [](https://expedia.ca/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![TownePlace Suites by Marriott Florence](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6_y.jpg) ### TownePlace Suites by Marriott Florence 10/10 Excellent "yes the room was clean and staff was good " [](https://expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Room was great and clean, staff friendly and helpful. " [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Hilton Garden Inn Florence](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/8b770330_y.jpg) ### Hilton Garden Inn Florence 10/10 Excellent "Clean, and great staff" [](https://expedia.ca/Florence-Hotels-Hilton-Garden-Inn-Florence.h1367205.Hotel-Information) ![Hampton Inn & Suites Florence-North-I-95](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e_y.jpg) ### Hampton Inn & Suites Florence-North-I-95 10/10 Excellent "The staff was amazing !" [](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Hampton Inn & Suites Florence Center](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003_y.jpg) ### Hampton Inn & Suites Florence Center 10/10 Excellent "Friendly staff and clean" [](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ## More cheap stays in Pamplico ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Howard Johnson by Wyndham Florence 2038 W Lucas Street Florence SC CA $91 CA $102 total Feb 16 - Feb 17 includes taxes & fees 8.6/10 Excellent! (2,566 reviews) [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Florence Civic Center 150 Dunbarton Dr Florence SC CA $115 CA $129 total Feb 23 - Feb 24 includes taxes & fees 7.8/10 Good! (1,264 reviews) [](https://expedia.ca/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Park Inn by Radisson Florence, SC 1729 Mandeville Road Florence SC CA $115 CA $129 total Feb 22 - Feb 23 includes taxes & fees 8.8/10 Excellent! (2,238 reviews) [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Best Western Inn](https://images.trvl-media.com/lodging/1000000/10000/500/455/344e3fdf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Inn 1808 W Lucas Street Florence SC CA $121 CA $136 total Feb 16 - Feb 17 includes taxes & fees 7.6/10 Good! (1,001 reviews) [](https://expedia.ca/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites Florence Center Area 527 Woody Jones Blvd Florence SC CA $134 CA $150 total Mar 1 - Mar 2 includes taxes & fees 9/10 Wonderful! (1,227 reviews) [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Hampton Inn & Suites Florence-North-I-95](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn & Suites Florence-North-I-95 1735 Stokes Road Florence SC CA $138 CA $155 total Feb 24 - Feb 25 includes taxes & fees 8.8/10 Excellent! (857 reviews) [](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ## Hotels in Pamplico with star rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 1 properties [](https://expedia.ca/4Star-Pamplico-Hotels.s40-0-d3000353197.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 13 properties [](https://expedia.ca/3Star-Pamplico-Hotels.s30-0-d3000353197.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 61 properties [](https://expedia.ca/2Star-Pamplico-Hotels.s20-0-d3000353197.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Pamplico? > This area is the heart of Pamplico, offering the most convenience for visitors. Main Street is where you'll find the majority of local businesses, including small shops and eateries, and it's easily navigable on foot. The town's historic charm is evident in the architecture of the older buildings lining the street. > > > For solo travellers or couples, staying within the town centre provides easy access to local life and amenities. You'll be able to stroll to local cafes for breakfast or explore the few boutique shops without needing a car. ### When is the best time to go to Pamplico? > These seasons offer pleasant weather conditions, with comfortable temperatures and lower humidity compared to the summer. This makes it ideal for enjoying outdoor activities and exploring the local area without the intense heat. > > > For those interested in local agricultural events and the natural beauty of the Pee Dee Region, these periods often coincide with local festivals and the blooming or changing colours of the landscape. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Pamplico hotel booking with Expedia? ### How much is the nightly rate at a Pamplico hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Cars - More ways to book - [5 Star Hotels in Florence ](https://www.expedia.ca/5Star-Florence-Hotels.s50-0-d1221.Travel-Guide-Filter-Hotels) - [Aynor Hotels ](https://www.expedia.ca/Aynor-Hotels.d3000353082.Travel-Guide-Hotels) - [Coward Hotels ](https://www.expedia.ca/Coward-Hotels.d3000353109.Travel-Guide-Hotels) - [Darlington Hotels ](https://www.expedia.ca/Darlington-Hotels.d7558.Travel-Guide-Hotels) - [Hotels near Darlington Raceway ](https://www.expedia.ca/Darlington-Raceway-Hotels.0-l6144924-0.Travel-Guide-Filter-Hotels) - 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