Title: Book The Best Hotels in Pamplico, SC for 2025 from CA $87 - Competitive Prices - Expedia.ca

 

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# Find hotels in Pamplico, SC from CA $87

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## Go beyond your typical stay in Pamplico

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America&regionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2025-11-28&d1=2025-11-28&endDate=2025-11-30&d2=2025-11-30&amenities=POOL)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America&regionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2025-11-28&d1=2025-11-28&endDate=2025-11-30&d2=2025-11-30&travelerType=family_friendly)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America&regionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2025-11-28&d1=2025-11-28&endDate=2025-11-30&d2=2025-11-30&amenities=PETS)

## Check prices for these dates

Tonight

[Nov 14 - Nov 15](https://www.expedia.ca/Hotel-Search?regionId=3000353197&startDate=2025-11-14&endDate=2025-11-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 15 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=3000353197&startDate=2025-11-15&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=3000353197&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=3000353197&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Compare 141 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

![Lobby](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/0da1bc1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/25ba1b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/079e4bcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/6fee16b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Executive Inn

Latta

8.2/10

Very good

(918)

"Check in pleasant. Second day no towels in room. Filthy. So bad we left and went elsewhere. Never again "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Charles Belmont

CA $137

CA $149 total

includes taxes & fees

Dec 7 - Dec 8

[](https://www.expedia.ca/Florence-Hotels-Best-Western-Executive-Inn.h1202776.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/59604fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/16ca8b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Snack bar](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/22eb9cd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Florence-North-I-95

Florence

9.0/10

Wonderful

(777)

"The room was spotless, check-in was courteous wonderful breakfast great hotel."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Roberta

CA $145

CA $162 total

includes taxes & fees

Dec 3 - Dec 4

[](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/f75cb7bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/8f02222f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/bf604151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Inn at the Crossroads

Lake City

9.4/10

Exceptional

(807)

"Extremely courteous staff; very clean and spacious room. Convenient to downtown shops and eateries. Definitely would stay again and recommend to friends and family."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Charlie

CA $169

CA $190 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/0ea8f0b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/83187168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee service](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/22e67acb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites Florence Center Area

Florence

9.2/10

Wonderful

(1140)

"Friendly staff, clean, great location near retail, restaurants and the highway."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dawn

CA $131

CA $146 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/5abcf1ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/b2e2f539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/bf29fa04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/1aa3f791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Staybridge Suites Florence - Civic Center by IHG

Florence

9.4/10

Exceptional

(913)

"Friendly staff, great breakfast, beautiful ammenities!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brandi

CA $184

CA $206 total

includes taxes & fees

Dec 11 - Dec 12

[](https://www.expedia.ca/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/51d8f371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Park Inn by Radisson Florence, SC

Florence

9.0/10

Wonderful

(2183)

"Friendly and efficient staff and a nice room for my overnight stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carole

CA $129

CA $145 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/ebea43b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Howard Johnson by Wyndham Florence

Florence

8.6/10

Excellent

(2437)

"Room clean, nice hot water in tub and friendly staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sharon

CA $91

CA $102 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/a45dedcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/dad4ec3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/cfe51644.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/9afe242f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residence Inn Marriott Florence

Florence

8.8/10

Excellent

(452)

"Great staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brian

CA $134

CA $150 total

includes taxes & fees

Dec 3 - Dec 4

[](https://www.expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/c105915a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/f63ba12c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/824b9567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Florence

Florence

8.0/10

Very good

(1675)

"Friendly staff, clean just what I was looking for!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bradford

CA $140

CA $156 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/bac50e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/ffb23f98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d1f8ba02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Florence Near Civic Center

Florence

6.8/10

(1003)

"It's only good for one night's sleep! Nothing more."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Wilian

CA $88

CA $99 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information)

![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/258371f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/024086db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/6676431c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn & Suites Florence Civic Center

Florence

7.8/10

Good

(1247)

"Room was spotless, bed extremely comfortable and staff was very helpful and courteous. Would DEFINITELY stay there again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tim

CA $119

CA $134 total

includes taxes & fees

Dec 13 - Dec 14

[](https://www.expedia.ca/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/86912dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5a5d3612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/7942388a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Florence I-20

Florence

9.0/10

Wonderful

(532)

"Always enjoy their breakfasts Clean rooms Comfy bed"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stacie

CA $145

CA $162 total

includes taxes & fees

Nov 19 - Nov 20

[](https://www.expedia.ca/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/a86309c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/719d7bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/w4000h2663x0y0-4c6e3b9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free cribs/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/67e23cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Florence

Florence

7.8/10

Good

(690)

" Wry nice place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tracy

CA $136

CA $152 total

includes taxes & fees

Dec 15 - Dec 16

[](https://www.expedia.ca/Florence-Hotels-Courtyard-By-Marriott-Florence.h84519.Hotel-Information)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/90a03799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/5961e0c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/ad99b77d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/b467d613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SpringHill Suites by Marriott Florence

Florence

8.6/10

Excellent

(958)

"Staff was very welcoming, friendly and professional. Very nice room, comfortable and clean. Great location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Krystal

CA $148

CA $166 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/25ce2409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/ab68742b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 2 Queen Beds](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/b510c653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/23e97d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home2 Suites by Hilton Florence, SC

Florence

8.2/10

Very good

(1001)

"great check in lady Kendra so nice"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brenda

CA $145

CA $162 total

includes taxes & fees

Dec 15 - Dec 16

[](https://www.expedia.ca/Florence-Hotels-Home2-Suites-By-Hilton-Florence.h7271220.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/0724af0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/a0ec666e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/92c4b04d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/da6adbe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aloft Florence

Florence

8.6/10

Excellent

(234)

"good stay "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Joanne

CA $130

CA $146 total

includes taxes & fees

Nov 18 - Nov 19

[](https://www.expedia.ca/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information)

![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/2aa0d516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/37047013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/1c7273f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/8756fe59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Florence Inn and Suites

Florence

6.4/10

(323)

"Clean and acceptable "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Benjamin

CA $77

CA $87 total

includes taxes & fees

Dec 15 - Dec 16

[](https://www.expedia.ca/Florence-Hotels-Florence-Inn-And-Suites.h20253.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/37f52847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/83cb7582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/94573105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Florence

8.6/10

Excellent

(1002)

"Room was spacious, clean and very bleachy smell. Staff was helpful. Morning staff very pleasant to deal with"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Curtis

CA $150

CA $168 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information)

![Desk, laptop workspace, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/a269d3f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Vending machine](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/222a1b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room, 1 King Bed (Smoke Free) | Room amenity](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/3d1c0a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/ada13811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Red Roof Inn Florence - Civic Center

Florence

6.8/10

(1003)

"Very clean"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susan

CA $79

CA $88 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/10000/500/455/344e3fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 10:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/500/455/5074ad24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/500/455/be7cdd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/455/af3985b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Inn

Florence

7.6/10

Good

(1001)

"Nice staff, clean rooms, easy access."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeffrey

CA $111

CA $124 total

includes taxes & fees

Dec 15 - Dec 16

[](https://www.expedia.ca/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-28&endDate=2025-11-29&regionId=3000353197&adults=2&sort=RECOMMENDED&openPlayBack=true)

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Save an average of 15% on thousands of hotels when you're signed in

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## More cheap stays in Pamplico

![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Howard Johnson by Wyndham Florence

2038 W Lucas Street, I-95 Exit 164, Florence, SC

CA $91

CA $102 total

Dec 2 - Dec 3

includes taxes & fees

8.6/10 Excellent! (2,426 reviews)

[](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information)

![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Park Inn by Radisson Florence, SC

1729 Mandeville Road, Florence, SC

CA $129

CA $145 total

Nov 16 - Nov 17

includes taxes & fees

8.8/10 Excellent! (2,186 reviews)

[](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information)

![Comfort Inn & Suites](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Comfort Inn & Suites

527 Woody Jones Blvd, Florence, SC

CA $131

CA $146 total

Nov 16 - Nov 17

includes taxes & fees

9/10 Wonderful! (1,135 reviews)

[](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information)

![Hampton Inn & Suites Florence-North-I-95](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn & Suites Florence-North-I-95

1735 Stokes Road, Florence, SC

CA $145

CA $162 total

Dec 2 - Dec 3

includes taxes & fees

8.8/10 Excellent! (777 reviews)

[](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information)

![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/b1bbd639_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Days Inn by Wyndham Florence/I-95 North

2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC

CA $86

CA $96 total

Nov 16 - Nov 17

includes taxes & fees

6.6/10 (1,002 reviews)

[](https://expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information)

![Tru by Hilton Florence I-95](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Tru by Hilton Florence I-95

2140 West Lucas Street, Florence, SC

CA $128

CA $148 total

Dec 3 - Dec 4

includes taxes & fees

8.2/10 Very Good! (1,002 reviews)

[](https://expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information)

## Hotels in Pamplico with star-rating

![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg)

4 Star Hotels

1 properties

[](https://expedia.ca/4Star-Pamplico-Hotels.s40-0-d3000353197.Travel-Guide-Filter-Hotels)

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

13 properties

[](https://expedia.ca/3Star-Pamplico-Hotels.s30-0-d3000353197.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

49 properties

[](https://expedia.ca/2Star-Pamplico-Hotels.s20-0-d3000353197.Travel-Guide-Filter-Hotels)

## Recent reviews of Pamplico hotels

![Comfort Inn & Suites](//images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg)

### Comfort Inn & Suites

5/5 Excellent

"The room was great, very clean & big. It was very comfortable. The staff was also great 👍, they were very accommodating, polite & kind. Good Place to Stay & I made sure to put their name in address in my book, because I'll definitely stay there again. I highly recommend The Comfort Inn & Suites."

A verified traveller stayed at Comfort Inn & Suites

Posted 4 days ago

[](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Florence](//images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg)

### La Quinta Inn & Suites by Wyndham Florence

5/5 Excellent

"Friendly staff, clean just what I was looking for!"

A verified traveller stayed at La Quinta Inn & Suites by Wyndham Florence

Posted 5 days ago

[](https://expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information)

![TownePlace Suites by Marriott Florence](//images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6_y.jpg)

### TownePlace Suites by Marriott Florence

5/5 Excellent

"We are repeat customers. We find the hotel customer friendly with friendly staff, clean rooms and a breakfast that is good & filling to start the next if our trip."

A verified traveller stayed at TownePlace Suites by Marriott Florence

Posted 5 days ago

[](https://expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information)

![Howard Johnson by Wyndham Florence](//images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg)

### Howard Johnson by Wyndham Florence

5/5 Excellent

"Staff was super friendly!"

A verified traveller stayed at Howard Johnson by Wyndham Florence

Posted 5 days ago

[](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information)

![Hampton Inn & Suites Florence-North-I-95](//images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e_y.jpg)

### Hampton Inn & Suites Florence-North-I-95

5/5 Excellent

"Gladys at the reception was very friendly and very helpful!"

A verified traveller stayed at Hampton Inn & Suites Florence-North-I-95

Posted 6 days ago

[](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information)

![Park Inn by Radisson Florence, SC](//images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg)

### Park Inn by Radisson Florence, SC

5/5 Excellent

"Room was comfortable. I didn't utilize the breakfast "

A verified traveller stayed at Park Inn by Radisson Florence, SC

Posted 6 days ago

[](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information)

![Microtel Inn & Suites by Wyndham Florence](//images.trvl-media.com/lodging/1000000/200000/200000/199996/cbd95825_y.jpg)

### Microtel Inn & Suites by Wyndham Florence

5/5 Excellent

"Staff was nice."

A verified traveller stayed at Microtel Inn & Suites by Wyndham Florence

Posted 7 days ago

[](https://expedia.ca/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information)

![Tru by Hilton Florence I-95](//images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg)

### Tru by Hilton Florence I-95

5/5 Excellent

"Everything was FANTASTIC. Clean, spacious room, nice decor, games in the lobby and outside a big connect four board. Lots of fun available. Breakfast had something unique and INCREDIBLE. They had a vanilla yogurt machine dispensing farm fresh yogurt that tasted incredible!!!! I WILL be back!!! Oh- the bed was wonderful as well"

A verified traveller stayed at Tru by Hilton Florence I-95

Posted 8 days ago

[](https://expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information)

![Aloft Florence](//images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/0724af0f_y.jpg)

### Aloft Florence

5/5 Excellent

"just need more luggage carts "

A verified traveller stayed at Aloft Florence

Posted 9 days ago

[](https://expedia.ca/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information)

## Frequently asked questions

### What's the best place for a stay in Pamplico?

> Located 20.9 mi (33.7 km) from the heart of Pamplico, [Park Inn by Radisson Florence, SC](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) is a top choice for your stay based on our traveler data. Other good options for your stay in the area are [Howard Johnson by Wyndham Florence](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) and [Comfort Inn & Suites Florence Center Area](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information). See all available [top hotels](https://www.expedia.ca/Hotel-Search?regionId=3000353197), or [vacation rentals in Pamplico](https://www.expedia.ca/Pamplico-Vacation-Rentals.d3000353197.Travel-Guide-VacationRentals).

### What are some of the best vacation rentals that Pamplico has to offer?

> [Walking distance from one of South Carolina's top Medical centers.](https://www.expedia.ca/Florence-Hotels-Walking-Distance-From-One-Of-South-Carolinas-Top-Medical-Centers.h79668437.Hotel-Information): Visitors like this Pamplico vacation home rental. It offers a garden, a selection of games, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all [vacation rentals in Pamplico](https://www.expedia.ca/Pamplico-Vacation-Rentals.d3000353197.Travel-Guide-VacationRentals).

### If I need to cancel my hotel reservation in Pamplico, will I receive a refund?

> Yes, most room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Filter your search by [fully refundable](https://www.expedia.ca/Hotel-Search?regionId=3000353197&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Pamplico.

### What is staying in Pamplico like?

> Visitors are sure to enjoy all that Pamplico has to offer. There are 135 hotels and other accommodations in the surrounding area. Find out more about [Pamplico](https://www.expedia.ca/Pamplico.dx3000353197).

### What should I see while I'm in Pamplico?

> Places to visit in the wider area include [Eastern Carolina Agricultural Fairgrounds](https://www.expedia.ca/Eastern-Carolina-Agricultural-Fairgrounds-Florence.d6162140.Vacation-Attraction), [Florence National Cemetery](https://www.expedia.ca/Florence-National-Cemetery-Florence.d553248621532657341.Vacation-Attraction), and [Florence Museum](https://www.expedia.ca/Florence-Museum-Florence.d6162137.Vacation-Attraction). You'll also find [Lynches River State Park](https://www.expedia.ca/Lynches-River-State-Park-South-Carolina.d630146808421969920.Vacation-Attraction) and [Lions Park](https://www.expedia.ca/Lions-Park-Lake-City.d553248621560871592.Vacation-Attraction) in the area. Check out what more to see and do in Expedia's [Pamplico guide](https://www.expedia.ca/Pamplico.dx3000353197).

### What's the weather like in Pamplico?

> The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Pamplico is 53 inches.

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-   [Flights to Florence](https://www.expedia.ca/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)
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-   [Flights from Butte (BTM) to Florence (FLO)](https://www.expedia.ca/lp/flights/btm/flo/butte-to-florence)
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-   [Flights from Toronto (YYZ) to Florence (FLO)](https://www.expedia.ca/lp/flights/yyz/flo/toronto-to-florence)

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-   [Book Hotels in Pamplico on Expedia.com](https://www.expedia.com/Pamplico-Hotels.d3000353197.Travel-Guide-Hotels)

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