Title: Mytilene Vacation Packages & Trips 2025/2026 | Expedia.ca [Hotels in Mytilene](https://expedia.ca/Mytilene-Hotels.d6062865.Travel-Guide-Hotels)[Vacation Rentals in Mytilene](https://expedia.ca/Mytilene-Vacation-Rentals.d6062865.Travel-Guide-VacationRentals)[Mytilene Car Rentals](https://expedia.ca/Car-Rentals-In-Mytilene.d6062865.Car-Rental-Guide) ![](https://images.trvl-media.com/place/181073/7db7a0e4-a4c2-4c5e-8866-ee0ae94b63e5.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mytilene Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings Photo by Hecktic Travels - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place #### Your Mytilene Vacation Unforgettable adventures await when you lock in a Mytilene vacation package. Whether you're a history buff, foodie or just a traveler who loves to see new places, there's something for everyone in this exciting city. A trip to Mytilene is an excellent opportunity to do some sightseeing. Be sure to visit popular attractions like [Mytilini Castle](https://www.expedia.ca/Mytilini-Castle-Greece.d6107138.Vacation-Attraction), [University of the Aegean](https://www.expedia.ca/University-Of-The-Aegean-Lesvos.d553248635056346865.Vacation-Attraction) and [Museum of the Memorial of the Refugees of 1922](https://www.expedia.ca/Museum-Of-The-Memorial-Of-The-Refugees-Of-1922-Greece.d553248621533101621.Vacation-Attraction). Your Mytilene vacation is just clicks away. Explore hotels, airfares and more on Expedia for a trip that's tailored to suit your travel style. ### Things to do in Mytilene Mytilene, located on the beautiful island of Lesvos, offers a delightful mix of beach, outdoor, and cultural activities. Visitors can indulge in wellness activities such as body treatments and spa experiences. The charming atmosphere also provides opportunities for educational exploration, making it a perfect destination for those seeking relaxation and enrichment amidst stunning surroundings. **Shopping** In Mytilene, explore the local markets for unique gifts and souvenirs, such as the bustling Mytilene Market, filled with local products and crafts. If you're up for a drive, visit the Elysium Shopping Mall, located 20.9km away, featuring a mix of retail shops and dining options. **Recreation** Thermes Gera Hot Springs offers a soothing retreat in Mytilene, featuring natural thermal waters known for their healing properties. Immerse yourself in a tranquil environment that promotes relaxation and rejuvenation, making it a perfect spot to unwind and de-stress during your vacation. **Adventure** In Mytilene, explore the crystal-clear waters with kayaking adventures along the coastline. Discover the area's rich history through hiking trails that lead to ancient ruins. For thrill-seekers, windsurfing at nearby beaches offers an exhilarating experience amidst stunning landscapes. **Nightlife** Experience Mytilene's vibrant nightlife at La Guitarra on Sapphous Street for live music and great cocktails. For a laid-back vibe, visit the Vintage Café on Eftalou Street, where you can enjoy local wines and socialize with friendly locals. *\*Distances are measured in a straight line; actual driving distances may vary depending on the route.* ### Find the best attractions in Mytilene Mytilene, located on the island of Lesvos in Greece, offers a perfect blend of beach, outdoor, and cultural experiences. Visitors can explore stunning beaches, historic churches, and the impressive Mytilene Castle. The area is ideal for families seeking a mix of culture and leisure, with various attractions catering to different interests. Enjoy a memorable vacation immersed in the rich heritage and natural beauty of Mytilene. - **Mytilini Castle:** Explore the impressive Mytilini Castle, a historic fort that dominates the skyline. Wander through its ancient walls, take in the stunning views of the city and the sea, and immerse yourself in the rich cultural heritage of Lesvos. - **University of the Aegean:** Visit the modern University of the Aegean, a vibrant hub of education and innovation. Enjoy the lively atmosphere, engage with local students, and appreciate the contemporary architecture amidst the historical backdrop of Mytilene. - **Thermi Beach:** Relax at Thermi Beach, a beautiful spot renowned for its serene atmosphere and crystal-clear waters. Enjoy sunbathing, swimming, or simply taking in the breathtaking coastal scenery. ### Best time to go to Mytilene The best time to visit Mytilene is dependant on what kind of holiday you are seeking. August is its hottest month on average. At this time, visitor numbers are high and weather is sunny with no rain. January is its coolest month on average. At this time, visitor numbers are low and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --- | --- | --- | --- | --- | --- | | January | 49.3°F (9.6°C) | Light Rain | Mostly Sunny | Low | Average | | February | 50.7°F (10.4°C) | Light Rain | Mostly Sunny | Low | Slightly Low | | March | 53.2°F (11.8°C) | Light Rain | Mostly Sunny | Average | Average | | April | 59.0°F (15.0°C) | Light Rain | Mostly Sunny | Average | Average | | May | 67.3°F (19.6°C) | No Rain | Sunny | Average | Average | | June | 75.0°F (23.9°C) | No Rain | Sunny | High | Slightly High | | July | 79.9°F (26.6°C) | No Rain | Sunny | High | Slightly High | | August | 80.1°F (26.7°C) | No Rain | Sunny | High | Slightly High | | September | 73.9°F (23.3°C) | No Rain | Sunny | Average | Average | | October | 65.8°F (18.8°C) | Light Rain | Sunny | Average | Average | | November | 59.7°F (15.4°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | December | 52.9°F (11.6°C) | Light Rain | Mostly Sunny | Low | Slightly Low | ### Booking tips and Expedia advantages for Mytilene To save money on your trip to Mytilene, consider visiting during the off-peak months of February and November to December, when hotel prices are lower. Booking your accommodation about a month in advance can help secure the best deals, especially if you check Expedia for last-minute discounts. Saturdays tend to be the cheapest days to stay, while Mondays are the most expensive. Additionally, consider combining hotel reservations with flights and activities for better package deals. Don't forget to explore free local attractions and use public transport, which is budget-friendly. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Mytilene are February and November to December, where the prices are slightly lower. This is in comparison to June to August, where prices are slightly higher. - **The best time to book a hotel:** Book your hotel in Mytilene about 1 month out to secure some of the cheapest prices. If you're the spontaneous type, Expedia's last minute deals and discounts are indicated via the green label below the price. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Mytilene is Saturday. The most expensive day to stay in Mytilene is Monday. - **Find cheap hotels on Expedia:** Utilize Expedia’s search tool to customize your travel preferences, such as your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels that are currently available. To find the best prices and deals, be sure to sort the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your Mytilene hotel reservations with your flights and activities through an Expedia package. ### Mytilene Beach Vacation Get set to live out those beachy daydreams on your upcoming Mytilene vacation. Set off on a lovely stroll, take in the sweeping ocean views and collect unique seashells during your trip to Mytilene. Located just 10 kilometres from the city center, Thermi Beach is the place to be for many travelers. Look through our Mytilene packages and watch your travel budget stretch further! ### Things You Should Know About Mytilene - If you want that beachside lifestyle, have a look at our [Mytilene beach hotels](https://www.expedia.ca/Mytilene-Hotels-Beach-Hotel.0-0-d6062865-tBeachHotel.Travel-Guide-Filter-Hotels?lang=en&rfrr=ATG.LP.BodyContent). Beautiful water views and refreshing sea air — what more could anyone want? - Take a look at [Sunrise Resort Hotel](https://www.expedia.ca/Lesvos-Hotels-Sunrise-Resort-Hotel.h23149752.Hotel-Information) and [Elysion Hotel](https://www.expedia.ca/Lesvos-Hotels-Elysion-Hotel.h3738267.Hotel-Information). These hotels might just be perfect for your vacation in Mytilene. - There are plenty of activities that keep the 28,300 or so residents of Mytilene busy. A quick look at our [Mytilene things to do page](https://www.expedia.ca/things-to-do/en/search?rid=6062865&rfrr=ATG.LP.BodyContent) will let you in on everything this place has to offer. - If you're searching for things to do while you're in town, add University of the Aegean, Thermi Beach and Port of Mytilene to your travel schedule. Also, take a look at our Mytilene vacation deals to save money on your experiences, hotels and more. ## Ready to book your vacation to Mytilene? Choose your dates ## Mytilene Hotel Deals ![Heliotrope Hotels](https://images.trvl-media.com/lodging/1000000/900000/890400/890395/a1f3c9aa_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Heliotrope Hotels Varia, Mytilene, Lesvos, Lesvos Island Fully refundableReserve now, pay when you stay CA $124 CA $140 total Nov 3 - Nov 4 includes taxes & fees 8.6/10 Excellent! (189 reviews) Stayed here both last year and this summer. Very convenient location between airport and city centre. There is a bus stop right across the hotel but taxi is also very affordable. They have a nice buffet breakfast and rooms are very clean. Friendly staff as well. Reviewed on Aug 26, 2025 [](https://expedia.ca/Hotel-Search?startDate=03%2F11%2F2025&endDate=04%2F11%2F2025&selected=890395&PinnedHotelID=890395&HadPinnedHotel=true®ionId=6062865) ![Theofilos Paradise Boutique Hotel](https://images.trvl-media.com/lodging/13000000/12320000/12319300/12319222/96fa5ce4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Theofilos Paradise Boutique Hotel 7, Skra str, Hatzidimitriou Park, Mytilene, Lesvos Fully refundableReserve now, pay when you stay 9.6/10 Exceptional! (158 reviews) Beautiful hotel e great staff and service. Perfect location. Great breakfast. My go to! I will pay the two night minimum even if I stay one night! Reviewed on Oct 3, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=16%2F11%2F2025&endDate=17%2F11%2F2025&selected=12319222&PinnedHotelID=12319222&HadPinnedHotel=true®ionId=6062865) [](https://expedia.ca/Hotel-Search?startDate=16%2F11%2F2025&endDate=17%2F11%2F2025&selected=12319222&PinnedHotelID=12319222&HadPinnedHotel=true®ionId=6062865) ![The Loriet](https://images.trvl-media.com/lodging/12000000/11100000/11098400/11098314/5445108d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Loriet Vareia, Mitilene, Lesvos, Lesvos Island Fully refundableReserve now, pay when you stay CA $82 CA $95 total Dec 1 - Dec 2 includes taxes & fees 8.2/10 Very Good! (75 reviews) Perfect hotel! Very authentic and beautiful. The only negative I would give is the lighting and the steps in the room. Reviewed on Aug 8, 2025 [](https://expedia.ca/Hotel-Search?startDate=01%2F12%2F2025&endDate=02%2F12%2F2025&selected=11098314&PinnedHotelID=11098314&HadPinnedHotel=true®ionId=6062865) [See all 166 properties in Mytilene](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=6062865) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental ### Lodging - [5 Star Hotels in Lesvos](https://www.expedia.ca/5Star-Lesvos-Hotels.s50-0-d181073.Travel-Guide-Filter-Hotels) - [Hotels near Bus Station](https://www.expedia.ca/Bus-Station-Hotels.0-l553248621557960386-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in North Aegean Islands](https://www.expedia.ca/Destinations-In-North-Aegean-Islands-Luxury-Hotel.0-0-d6051354-tLuxuryHotel.Hotel-Filter-Destinations) - [Farmstay in Lesvos](https://www.expedia.ca/Lesvos-Agritourism.d181073-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in Lesvos](https://www.expedia.ca/Lesvos-Apart-Hotels.d181073-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Lesvos](https://www.expedia.ca/Lesvos-Apartments.d181073-aaApartments.Travel-Guide-Accommodation) - [B&B in Lesvos](https://www.expedia.ca/Lesvos-Bed-And-Breakfast.d181073-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hostels in Lesvos](https://www.expedia.ca/Lesvos-Hostels.d181073-aaHostels.Travel-Guide-Accommodation) - 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[Flights from Porto to Lesvos](https://www.expedia.ca/lp/flights/603077/181073/porto-to-lesvos) - [Flights from Robinsonville - Tunica to Lesvos](https://www.expedia.ca/lp/flights/6048540/181073/robinsonville-tunica-to-lesvos) - [Flights from Milas to Lesvos](https://www.expedia.ca/lp/flights/6050250/181073/milas-to-lesvos) - [Flights from Hannover to Lesvos](https://www.expedia.ca/lp/flights/6050602/181073/hannover-to-lesvos) - [Flights from Newport News to Lesvos](https://www.expedia.ca/lp/flights/6056964/181073/newport-news-to-lesvos) - [Flights from Çanakkale to Lesvos](https://www.expedia.ca/lp/flights/6134118/181073/canakkale-to-lesvos) - [Flights from Pleurtuit to Lesvos](https://www.expedia.ca/lp/flights/6157100/181073/pleurtuit-to-lesvos) - [Flights from Kefalonia to Lesvos](https://www.expedia.ca/lp/flights/6244029/181073/kefalonia-to-lesvos) - [Flights from West Harrison to Lesvos](https://www.expedia.ca/lp/flights/6348023/181073/west-harrison-to-lesvos) - [Flights from Iamalele to Lesvos](https://www.expedia.ca/lp/flights/7900/181073/iamalele-to-lesvos) - [Flights from Central to Lesvos](https://www.expedia.ca/lp/flights/805/181073/central-to-lesvos) - [Flights from Ciudad del Carmen to Lesvos](https://www.expedia.ca/lp/flights/871/181073/ciudad-del-carmen-to-lesvos) - [Flights from Nanded to Lesvos](https://www.expedia.ca/lp/flights/8972/181073/nanded-to-lesvos) - [Flights from Amsterdam (AMS) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/ams/mjt/amsterdam-to-mytilene) - [Flights from Athens (ATH) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/ath/mjt/athens-to-mytilene) - [Flights from Beirut (BEY) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/bey/mjt/beirut-to-mytilene) - [Flights from Edremit (EDO) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/edo/mjt/edremit-to-mytilene) - [Flights from Rome (FCO) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/fco/mjt/rome-to-mytilene) - [Flights from Patras (GPA) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/gpa/mjt/patras-to-mytilene) - [Flights from Istanbul (IST) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/ist/mjt/istanbul-to-mytilene) - [Flights from London (LHR) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/lhr/mjt/london-to-mytilene) - [Flights from Munich (MUC) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/muc/mjt/munich-to-mytilene) - [Flights from Paphos (PFO) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/pfo/mjt/paphos-to-mytilene) - [Flights from Samos (SMI) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/smi/mjt/samos-to-mytilene) - [Flights from Ottawa (YOW) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/yow/mjt/ottawa-to-mytilene) - [Flights from Toronto (YTZ) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/ytz/mjt/toronto-to-mytilene) - [Flights from Montreal (YUL) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/yul/mjt/montreal-to-mytilene) - [Flights from Vancouver (YVR) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/yvr/mjt/vancouver-to-mytilene) - [Flights from Calgary (YYC) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/yyc/mjt/calgary-to-mytilene) - [Flights from Toronto (YYZ) to Mytilene (MJT)](https://www.expedia.ca/lp/flights/yyz/mjt/toronto-to-mytilene) ### Packages - [Lesvos Vacations](https://www.expedia.ca/Lesvos.d181073.Destination-Travel-Guides) - [Visit Lesvos](https://www.expedia.ca/Lesvos.dx181073) - [Vatera Vacations](https://www.expedia.ca/Vatera.d6052053.Destination-Travel-Guides) ### Cars - [Alamo Rent A Car Rental Cars in Lesvos](https://www.expedia.ca/Alamo-Rent-A-Car-Car-Rentals-In-Lesvos.d181073-c6.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Lesvos](https://www.expedia.ca/Avis-Car-Rentals-In-Lesvos.d181073-c41.Car-Rental-Guide-Suppliers) - [Budget Rental Cars in Lesvos](https://www.expedia.ca/Budget-Car-Rentals-In-Lesvos.d181073-c39.Car-Rental-Guide-Suppliers) - [Car rental Lesvos](https://www.expedia.ca/Car-Rentals-In-Lesvos.d181073.Car-Rental-Guide) - [Rental cars Mytilene Intl. airport](https://www.expedia.ca/Car-Rentals-In-Mytilene-Intl.d6030104.Car-Rental-Guide) - [Car rentals near Port of Mytilene](https://www.expedia.ca/Car-Rentals-In-Port-Of-Mytilene.d553248621563225013.Car-Rental-Guide) - [Europcar Rental Cars in Lesvos](https://www.expedia.ca/Europcar-Car-Rentals-In-Lesvos.d181073-c14.Car-Rental-Guide-Suppliers) - [Orlando Rental Cars in Lesvos](https://www.expedia.ca/Orlando-Car-Rentals-In-Lesvos.d181073-c1047.Car-Rental-Guide-Suppliers) - [Sixt Rental Cars in Lesvos](https://www.expedia.ca/Sixt-Car-Rentals-In-Lesvos.d181073-c35.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in Lesvos](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Lesvos.d181073-c45.Car-Rental-Guide-Suppliers) ### Vacation Rental - [Lesvos Vacation Rentals](https://www.expedia.ca/Lesvos-Vacation-Rentals.d181073.Travel-Guide-VacationRentals) \* Savings based on package bookings compared to the price of the same components booked separately. 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