Medical Center Area Vacation Packages

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  • Better together

    Save up to CA $1,096 when you book a flight and hotel together*

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Top Holiday Package Deals in Medical Center Area

Price found within the past 48 hours. Click for updated prices.
The Atlas Hotel

The Atlas Hotel

4.5 out of 5
Allston
Price was CA $2,529, price is now CA $1,545 per person
CA $1,545
per person
May 25 - May 29
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Boston (BOS)
10/10 Exceptional! (18 reviews)
We absolutely loved our stay at this new hotel. My family and I kept saying what a really nice hotel and the staff was great as well. The food at Ama (we ate breakfast) was delicious. The property is beautiful. Can’t wait to stay again.

Reviewed on Apr 5, 2026

The Inn at Hastings Park, Relais & Chateaux - Boston

The Inn at Hastings Park, Relais & Chateaux - Boston

4 out of 5
Price was CA $2,994, price is now CA $1,758 per person
CA $1,758
per person
Jun 22 - Jun 27
found 3 hours ago
Roundtrip flight included
Detroit (DTW) to Boston (BOS)
9.6/10 Exceptional! (253 reviews)
Excellent experience- clean and very helpful staff

Reviewed on Mar 9, 2026

Eurostars The Boxer

Eurostars The Boxer

4 out of 5
West End
Price was CA $3,492, price is now CA $2,087 per person
CA $2,087
per person
Jun 22 - Jun 27
found 3 hours ago
Roundtrip flight included
Detroit (DTW) to Boston (BOS)
8.8/10 Excellent! (1,426 reviews)
Staff was great room was cute!

Reviewed on Apr 10, 2026

Raffles Boston

Raffles Boston

5 out of 5
Back Bay
Price was CA $5,722, price is now CA $3,647 per person
CA $3,647
per person
Jun 22 - Jun 27
found 3 hours ago
Roundtrip flight included
Detroit (DTW) to Boston (BOS)
9.6/10 Exceptional! (248 reviews)
The photos doesn’t give this place justice.

Reviewed on Mar 24, 2026

Club Quarters Hotel Faneuil Hall, Boston

Club Quarters Hotel Faneuil Hall, Boston

4 out of 5
Downtown Boston
Price was CA $2,933, price is now CA $1,916 per person
CA $1,916
per person
Jun 22 - Jun 27
found 3 hours ago
Roundtrip flight included
Detroit (DTW) to Boston (BOS)
9/10 Wonderful! (3,000 reviews)
Room is simple and clean for a short stay. Younhabe everything you need within walking distance of the hotel. Additionally, they have discounted overnight parking with a local facility.

Reviewed on Apr 8, 2026

Where to stay in Medical Center Area

Find the best Medical Center Area areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center Area
Downtown Boston

Downtown Boston

4.5/5(197 area reviews)

Densely packed with highrise buildings, this area boasts landmarks like Custom House Tower and is close to Quincy Market, Faneuil Hall, and the Old State House. Find headquarters of major banks, hotels, and investment firms here.

Find hotels in Downtown Boston

Medical Center Area Hotel Deals

Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport

5 out of 5
450 Summer Street Boston MA
Fully refundableReserve now, pay when you stay
The price is CA $281 per night from May 10 to May 11
CA $281
CA $384 total
May 10 - May 11
includes taxes & fees
9.2/10 Wonderful! (4,579 reviews)
Impressive

Reviewed on Apr 10, 2026

Omni Boston Hotel at the Seaport
Seaport Hotel Boston

Seaport Hotel Boston

4 out of 5
1 Seaport Lane Boston MA
Fully refundableReserve now, pay when you stay
The price is CA $209 per night from May 10 to May 11
CA $209
CA $291 total
May 10 - May 11
includes taxes & fees
9.6/10 Exceptional! (4,159 reviews)
Pretty snug for 4 people in a room and beds are small. Didn’t spend an awful lot of time in the room so no major issue. Bar area nice and good good. Checkin easy and staff polite and helpful.

Reviewed on Apr 10, 2026

Seaport Hotel Boston
Hilton Boston Park Plaza

Hilton Boston Park Plaza

4 out of 5
50 Park Plaza Boston MA
The price is CA $285 per night from May 10 to May 11
CA $285
CA $389 total
May 10 - May 11
includes taxes & fees
8.4/10 Very Good! (3,146 reviews)
Rooms could use an update and refresh

Reviewed on Apr 9, 2026

Hilton Boston Park Plaza
See all 4,167 properties in Medical Center Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Medical Center Area vacation package cost?
From as little as CA $1,545, you can create your own Medical Center Area package the way you want. Simply bundle hotels, flights and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Medical Center Area?
Bundling your flight and hotel with Expedia won't just save precious time — it'll save you a nice amount too. A Medical Center Area vacation package makes it simple to arrange your ideal trip. With more than 550 airlines across the world to pick from, finding flights that fit your busy schedule will be no sweat. In addition to that, we have over 1,000,000 hotels globally to choose from. Now that's what you call choice. No matter who you are, Expedia puts the world within your reach.
Where should I stay in Medical Center Area?
Visitors come from all over the world to experience Fenway Park and TD Garden in Medical Center Area. Stay within walking distance of these top attractions to make sightseeing easy.
What are the top hotels in Medical Center Area?
If it's comfort and convenience you want, you can't beat The Inn at Longwood Medical. Spend your evenings relaxing here and your days roaming around Medical Center Area's finest sights.
How far in advance should I book my Medical Center Area vacation?
While prices change from time to time, we generally suggest booking your vacation as early as possible. Most international airfares can be compared on Expedia up to 12 months in advance. If you're booking last minute, you might still be in luck. Cheap journeys to Medical Center Area sometimes emerge only weeks before departure.
What does an Expedia Medical Center Area travel package include?
Packages include flights, rental cars and hotels, but you can combine any of them to create your dream Medical Center Area escape. You can also add on fun things like activities and experiences once you've made your booking. You're in control! When you bundle your bookings with Expedia, you'll get access to discounts you won't find elsewhere.
What should I know before booking a Medical Center Area travel package?
You can save big by bundling your hotels, airfares and rental cars. Once you've created your package, you can add on sightseeing tours or experiences. Your next awesome vacation is only a few clicks away.
Can I choose my airline with a Medical Center Area Expedia vacation package?
You certainly can. We offer more than 550 airline partners across the globe, so fly with the carrier that's a good fit for your needs.
If I'm not able to travel, can I cancel my Medical Center Area vacation package?
If your travel plans in Medical Center Area have changed, it's good to know that you can amend or cancel your booking. If you made your booking within the last 24 hours, you may be eligible to receive a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may charge a cancellation fee. For more information, visit our Customer Service Portal.

Discover the most popular places to visit in Medical Center Area

Isabella Stewart Gardner Museum

Isabella Stewart Gardner Museum

A world-renowned private collection of art and cultural treasures awaits at this small yet lavish museum.

Isabella Stewart Gardner Museum

Boston Children's Hospital

Though Boston Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Boston while you are here.

Boston Children's Hospital

Dana-Farber Cancer Institute

Though Dana-Farber Cancer Institute might be what brings you to town, perhaps you'll have a chance to explore more of Boston while you are here.

Dana-Farber Cancer Institute

Things to do

Boston Hop-On Hop-Off Trolley Tour

Boston Old Town Trolley Hop-on Hop-Off City Tour

CA $72
per adult
90% of travellers recommend
Boston Old Town Trolley Hop-on Hop-Off City Tour
Boston CityPASS: Admission to Top 4 Boston Attractions

Boston CityPASS®: Admission to Top 4 Attractions

CA $115
per adult
92% of travellers recommend
Boston CityPASS®: Admission to Top 4 Attractions
Go City: Boston All-Inclusive Pass with 45+ Attractions

Go City: Boston All-Inclusive Pass with 45+ Attractions

CA $108
per adult
80% of travellers recommend
Go City: Boston All-Inclusive Pass with 45+ Attractions
See all activities in Boston
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.