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Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is CA $136 per night from Feb 16 to Feb 17
CA $136
CA $153 total
Feb 16 - Feb 17
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,003 reviews)
The room was great. The facility was excellent. The people were excellent. Definitely going back.
Reviewed on Feb 5, 2026
The Riverview
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is CA $125 per night from Feb 16 to Feb 17
CA $125
CA $142 total
Feb 16 - Feb 17
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.4/10 Exceptional! (499 reviews)
The hotel was so nice! We planned this trip for my husbands 40th birthday, and I called ahead to see if they did anything for birthdays and they gave us a complementary upgrade on our room. I was taken back on that and thought it was so kind and generous. I wasn’t expecting that - I would have been ...
Reviewed on Feb 1, 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
The price is CA $114 per night from Feb 16 to Feb 17
CA $114
CA $123 total
Feb 16 - Feb 17
includes taxes & fees
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (700 reviews)
Clean room, friendly staff, good breakfast. The only complaint is neither of the water fountains in the fitness center work
Reviewed on Feb 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Little Blue Cottage on Spanish
Cape Girardeau MO
Stay at this vacation home in Cape Girardeau. Popular attractions eDen Spa & Salon and The Glenn House are located nearby.
8.2/10 Very Good! (49 reviews)
Great cute place.
Reviewed on Jan 21, 2026
Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau MO
Book a stay at this family-friendly vacation home in Cape Girardeau. Enjoy a water park, a garden, and patios. Popular attractions eDen Spa & Salon and The Glenn ...
10/10 Exceptional! (150 reviews)
It's a great location, great space, great price. And, the muffins are the best!
Reviewed on Jan 12, 2026
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau MO
Stay at this vacation home in Cape Girardeau. Enjoy free WiFi, private pools, and a garden. Popular attractions Twin Trees Park and Cape Rock Park are located ...
8.6/10 Excellent! (38 reviews)
Very clean and relaxing. Very nice weekend getaway. We will definitely be back.
Reviewed on Jan 10, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
