Jefferson County Vacation Packages

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  • Better together

    Save up to CA $1,096 when you book a flight and hotel together*

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Your Jefferson County Vacation

Choose a vacation package to Jefferson County and make travel planning a breeze. With the logistics taken care of before you leave, you can focus on enjoying every second in this wonderful destination. Not sure where to stay? Festus is among the leading cities to visit during a trip to Jefferson County. If you're ready to stop dreaming and start packing, Expedia will help turn your Jefferson County vacation into a reality.

Top Jefferson County Vacation Deals

Price found within the past 48 hours. Click for updated prices.
The Knight Center at Washington University

The Knight Center at Washington University

2.5 out of 5
Price was CA $826, price is now CA $658 per person
CA $658
per person
Apr 22 - Apr 25
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
9.4/10 Exceptional! (425 reviews)
Very clean rooms. Clean and fresh feeling. Appreciated the bathrooms looking so nice and clean too! Will definitely stay there again. Only thing I’d change is I wish there were microwaves in the room.

Reviewed on Feb 16, 2026

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $1,363, price is now CA $879 per person
CA $879
per person
Mar 30 - Apr 3
found 1 hour ago
Roundtrip non-stop flight included
Montreal (YUL) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Great staff. Safe place within walking distance of restaurants and activities. Clean room.

Reviewed on Feb 19, 2026

Landing Apartments - Eureka

Landing Apartments - Eureka

4 out of 5
Price was CA $1,662, price is now CA $1,351 per person
CA $1,351
per person
Mar 30 - Apr 3
found 1 hour ago
Roundtrip non-stop flight included
Montreal (YUL) to St. Louis (STL)
No reviews
The Cheshire

The Cheshire

4 out of 5
Price was CA $841, price is now CA $685 per person
CA $685
per person
Apr 22 - Apr 25
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
8.6/10 Excellent! (1,002 reviews)
Room was great breakfast was great

Reviewed on Feb 14, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Price was CA $841, price is now CA $694 per person
CA $694
per person
Apr 22 - Apr 25
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
8.4/10 Very Good! (1,006 reviews)
Room was clean, plenty of space

Reviewed on Feb 11, 2026

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Jefferson County Hotel Deals

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $173 per night from Mar 15 to Mar 16
CA $173
CA $209 total
Mar 15 - Mar 16
includes taxes & fees
9/10 Wonderful! (1,616 reviews)
Staff and amenities were great. Bathroom and Carpet clea miess

Reviewed on Feb 21, 2026

21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $144 per night from Feb 26 to Feb 27
CA $144
CA $168 total
Feb 26 - Feb 27
includes taxes & fees
8.8/10 Excellent! (3,091 reviews)
Great place to stay! Clean rooms, comfortable beds, and great breakfast! Highly recommend if you’re looking for a place to stay!

Reviewed on Feb 22, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from Mar 1 to Mar 2
CA $123
CA $145 total
Mar 1 - Mar 2
includes taxes & fees
9.4/10 Exceptional! (2,835 reviews)
Good location and efficient services. Room is clean and plenty of free parking space.

Reviewed on Feb 22, 2026

Pear Tree Inn St. Louis Airport
See all 1,985 properties in Jefferson County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
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Frequently asked questions

How much does a Jefferson County vacation package cost?
Our Jefferson County packages, which begin at just CA $658, are the perfect way to save money. Select your favorite hotels, flights and more to create a customized trip.
How do I get a cheap travel package to Jefferson County?
Combine your hotel and flight bookings, add on extras such as tours, and save with a Jefferson County vacation package. You won't just pick up exciting discounts on your escape — you'll have plenty of choice within your reach too. When you book through Expedia, you'll have your pick of over 550 air carriers and 1,000,000 properties globally. Your affordable vacation begins right here, right now!
What are the top hotels in Jefferson County?
For hotels in De Soto with cozy beds and friendly service, you can't go past Pear Tree Inn St. Louis Arnold and Quality Inn & Suites Arnold - St Louis. If you plan to visit Festus as well, you'll get a great night's sleep at Comfort Inn Festus - St Louis South or La Quinta Inn & Suites by Wyndham Festus - St. Louis South.
How far in advance should I book my Jefferson County vacation?
Travelers are generally able to compare international airfares on Expedia within 12 months of the departure date. Booking at the last minute? With a stroke of luck, it's still possible to purchase a cheaper ticket just weeks before your journey.
What does an Expedia Jefferson County travel package include?
Select from a combination of hotels, rental cars and flights. Once you've made your booking, you can also add on experiences and activities. Want to pick your fare class? That's easy to do too. The choice is all yours when it comes to planning your ideal Jefferson County trip.
What should I know before booking a Jefferson County travel package?
When you book your hotels, flights and car rentals together, you'll be rewarded with terrific discounts. Whether you're organizing a beach break in a villa or prefer to stay in a ritzy city hotel, Expedia will make it happen for less.
Can I choose my airline with a Jefferson County Expedia vacation package?
You can, and with over 550 airlines to select from across the globe, you're not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Jefferson County vacation package?
Your situation can change without warning, so yes. You may be able to cancel or alter your Jefferson County vacation package at no cost if you've booked in the last 24 hours. For older bookings, you can still cancel or make changes, but your airline, hotel or car rental company may charge a fee. Need more information? Check out our Customer Service Portal. We'll help make sure your trip goes off without a hitch.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.