Columbus Vacation Packages

Name: Quality Inn Cairo I-57
Price range: CA $100

Book a Hotel + Flight or Car together to unlock savings

Plan, book, travel with confidence
Better together
Save up to CA $4,200 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Your Columbus Vacation

Take away the hard part of planning your next big adventure with a Columbus vacation package. Whether you've come for its food, history, art or other highlights, there's an inexhaustible array of experiences to be had. Wondering what you should do or see first during your trip to Columbus? Check off famous attractions such as Columbus-Belmont State Park. Whoever you're heading away with and whatever your bank balance, your ultimate Columbus vacation is just a few clicks away with Expedia.

Ready to book your vacation to Columbus?

Choose your dates

Columbus Hotel Deals

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

Fully refundableReserve now, pay when you stay

CA $84

CA $94 total

Jun 2 - Jun 3

includes taxes & fees

6.6/10 (637 reviews)

"Clean rooms,"

Reviewed on May 31, 2026

The Riverstone Hotel Charleston-Sikeston

102 Drake St Charleston MO

Fully refundableReserve now, pay when you stay

CA $103

CA $115 total

Jun 2 - Jun 3

includes taxes & fees

6.8/10 (413 reviews)

"They cha rged me twice. They promised a refund but I have not seen it yet. Windows was taped up so I could not see out. Room smelled bad. I was also unhappy with the Expedia app."

Reviewed on Jun 1, 2026

Quality Inn Cairo I-57

13201 Kessler Road Cairo IL

Fully refundable

CA $100

CA $111 total

Jun 20 - Jun 21

includes taxes & fees

See all 9 properties in Columbus

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.