Title: Hotels by La Quinta Inn & Suites in Wykoff from CA $114 | Expedia.ca [Wykoff Travel Guide](https://expedia.ca/Wykoff.dx3000443967)[Hotels in Wykoff](https://expedia.ca/Wykoff-Hotels.d3000443967.Travel-Guide-Hotels)[Vacation Rentals in Wykoff](https://expedia.ca/Wykoff-Vacation-Rentals.d3000443967.Travel-Guide-VacationRentals)[Flights to Wykoff](https://expedia.ca/Cheap-Flights-To-Wykoff.d3000443967.Travel-Guide-Flights)[Wykoff Car Rentals](https://expedia.ca/Car-Rentals-In-Wykoff.d3000443967.Car-Rental-Guide)[Wykoff Vacation Packages](https://expedia.ca/Wykoff.d3000443967.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 10 - Mar 11](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-03-10&endDate=2026-03-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 11 - Mar 12](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-03-11&endDate=2026-03-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Wykoff La Quinta Inn & Suites ![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's pool](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/adc84b77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/76e5e57e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/1a6136b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S [](https://www.expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) Rochester 7.2/10 Good (1,039 reviews) "Staff was courteous and breakfast was well stocked." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doug CA $99 CA $114 total includes taxes & fees Mar 20 - Mar 21 [](https://www.expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-24&endDate=2026-03-25®ionId=3000443967&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels-La-Quinta-Inn-Suites.0-0-d3000443967--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels-La-Quinta-Inn-Suites.0-0-d3000443967--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Wykoff Hotel Reviews ![Holiday Inn Express Rochester South - Mayo Area by IHG](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/d5501184_y.jpg) ### Holiday Inn Express Rochester South - Mayo Area by IHG 6/10 Okay "Muggy, warm room, " [](https://expedia.ca/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-1092e125_y.jpg) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 8/10 Good "Property and rooms were fine. Staff was very good. Definitely had the smell of a waterpark throughout." [](https://expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Aspen Select](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/31690353_y.jpg) ### Aspen Select 6/10 Okay "Great location across from St. Mary’s. Reasonably priced. Shower felt good, but water pressure noise, shower head handle, and shower head questionable. Drapes open up to hallway, so no natural sunlight. Good place to stay for a quick night’s sleep. " [](https://expedia.ca/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/c73455d9_y.jpg) ### Hampton Inn Rochester-South 10/10 Excellent "Check in staff" [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "The room was clean. The breakfast was simple but good options. Coffee was strong and good. I would recommend this hotel to anyone. Great price and not far from shopping and downtown. " [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/404886d5_y.jpg) ### Aspen Suites 8/10 Good "Aspen Suits is perfect for our needs. Staff is helpful kind and very organized. check in and check out takes seconds. The evening snack social is welcome hospitality addition." [](https://expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/1062bbaa_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Great place to stay for Mayo checkups, always clean & couldn’t be more convenient " [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG 10/10 Excellent "Clean rooms" [](https://expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/64f360d1_y.jpg) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys 10/10 Excellent "The bathroom floor had water damage, but everything else was great, especially the staff; they are very kind and accommodating. Breakfast was great as well." [](https://expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [4 Star Hotels in Stewartville ](https://www.expedia.ca/4Star-Stewartville-Hotels.s40-0-d183438.Travel-Guide-Filter-Hotels) - [Hyatt Hotels in Apple Valley ](https://www.expedia.ca/Apple-Valley-Hotels-Hyatt-Hotels.0-0-d6003--bHyattHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Bancroft ](https://www.expedia.ca/Bancroft-Minneapolis-St-Paul-Hotels-Hilton-Hotels.0-n553248635976472057-0--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Bayport ](https://www.expedia.ca/Bayport-Hotels-Hilton-Hotels.0-0-d3000442965--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Accor Hotels in Bloomington ](https://www.expedia.ca/Bloomington-Hotels-Accor-Hotels.0-0-d6287--bAccorHotels.Travel-Guide-Filter-Hotels) - [Best Western Hotels in Bloomington ](https://www.expedia.ca/Bloomington-Hotels-Best-Western.0-0-d6287--bBestWestern.Travel-Guide-Filter-Hotels) - 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