Vermillion Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Vermillion Vacation

When you lock in a vacation package to Vermillion, all the planning is done in advance. This gives you plenty of time to uncover some of the things that define this historic city, such as its small-town feel, laid-back lifestyle and welcoming locals. If your trip to Vermillion includes a little sightseeing, hit up popular attractions like University of South Dakota, DakotaDome and National Music Museum. Stop dreaming and start traveling. Browse the broad range of options on Expedia today and put your Vermillion vacation plans into gear!

Ready to book your vacation to Vermillion?

 

Choose your dates

Vermillion Hotel Deals

Best Western Vermillion Inn

Best Western Vermillion Inn

2.5 out of 5
701 W Cherry St Vermillion SD
Fully refundableReserve now, pay when you stay
The price is CA $131 per night from May 20 to May 21
CA $131
CA $145 total
May 20 - May 21
includes taxes & fees
8.8/10 Excellent! (584 reviews)
Clean and well maintained.

Reviewed on Apr 7, 2026

Best Western Vermillion Inn
Red Roof Inn Vermillion - U of South Dakota

Red Roof Inn Vermillion - U of South Dakota

2 out of 5
1208 E Cherry St Vermillion SD
Fully refundableReserve now, pay when you stay
The price is CA $104 per night from May 20 to May 21
CA $104
CA $116 total
May 20 - May 21
includes taxes & fees
8/10 Very Good! (443 reviews)
Mold in bathroom along base of tub. Door frame to the adjoining room was loose, so door could not be locked. Coffee maker in room leaked all over. Staff did find another one for us to use.

Reviewed on Apr 22, 2026

Red Roof Inn Vermillion - U of South Dakota
Prairie Inn

Prairie Inn

2 out of 5
916 N Dakota Street Vermillion SD
The price is CA $95 per night from May 11 to May 12
CA $95
CA $103 total
May 11 - May 12
includes taxes & fees
Prairie Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Vermillion

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.