Downtown Clayton
St. Louis
Visit Downtown Clayton
Things to do
StL's Signature "Sights and Bites" - Private Tour in St. Louis
CA $247
per adult
Haunted Lemp Brewery Bottle Works Paranormal Tour
CA $35
per adult
St. Louis Burlesque & Nightlife Experience at The Boom Boom Room
CA $85
per adult
100% of travellers recommend
Self-Guided Audio Tour of Gateway Arch National Park & St. Louis
CA $21
per traveller
Downtown Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
The price is CA $148 per night from Dec 6 to Dec 7
CA $148
CA $172 total
Dec 6 - Dec 7
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,530 reviews)
"The staff were very kind and welcoming! We enjoyed our stay. The rooms were very clean and comfortable. It also has a lovely breakfast. My favorite part about my stay was definitely the entire staff though I can’t say enough how wonderful everyone was."
Reviewed on Nov 9, 2026
Le Méridien St. Louis Clayton
7730 Bonhomme Ave St. Louis MO
The price is CA $215 per night from Nov 22 to Nov 23
CA $215
CA $253 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
AC Hotel St. Louis Clayton
227 South Central Ave St. Louis MO
The price is CA $181 per night from Nov 15 to Nov 16
CA $181
CA $212 total
Nov 15 - Nov 16
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
9.2/10 Wonderful! (426 reviews)
"Nice place very clean, shower pressure was kind of weak"
Reviewed on Nov 7, 2026
The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
The price is CA $776 per night from Nov 27 to Nov 28
CA $776
CA $905 total
Nov 27 - Nov 28
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the room ...
9.2/10 Wonderful! (588 reviews)
"Great amenities."
Reviewed on Nov 8, 2026
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
The price is CA $127 per night from Nov 15 to Nov 16
CA $127
CA $151 total
Nov 15 - Nov 16
includes taxes & fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
The price is CA $203 per night from Nov 15 to Nov 16
CA $203
CA $238 total
Nov 15 - Nov 16
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,828 reviews)
"Free breakfast was great. Staff were very nice. Rooms were clean. Highly recommend."
Reviewed on Nov 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Downtown Clayton hotel availability
Where to stay in Downtown Clayton
Find the best Downtown Clayton areas and neighborhoods for the activities you enjoy most.
Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
St. Charles Historic District
St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.
Central West End
The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
