Title: Santiago del Estero Vacation Packages & Trips 2026 | Expedia.ca [Hotels in Santiago del Estero](https://expedia.ca/Santiago-Del-Estero-Hotels.d3107.Travel-Guide-Hotels)[Vacation Rentals in Santiago del Estero](https://expedia.ca/Santiago-Del-Estero-Vacation-Rentals.d3107.Travel-Guide-VacationRentals)[Flights to Santiago del Estero](https://expedia.ca/Cheap-Flights-To-Santiago-Del-Estero.d3107.Travel-Guide-Flights)[Santiago del Estero Car Rentals](https://expedia.ca/Car-Rentals-In-Santiago-Del-Estero.d3107.Car-Rental-Guide) ![](https://images.trvl-media.com/place/3107/5597c51f-4875-4ad5-801c-9eebf927b11d.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santiago del Estero Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place #### Your Santiago del Estero Vacation Noted for its cultural experiences and rich history, Santiago del Estero is a fabulous getaway destination. Lock in one of our Santiago del Estero vacation packages and uncover all that this interesting city has to offer. Want to venture out and explore? [Brisas Spa](https://www.expedia.ca/Brisas-Spa-Santiago-del-Estero.d553248621532463847.Vacation-Attraction), [Plaza Sarmiento](https://www.expedia.ca/Plaza-Sarmiento-Santiago-del-Estero.d6097304.Vacation-Attraction) and [Santiago del Estero Cathedral](https://www.expedia.ca/Santiago-Del-Estero-Cathedral-Santiago-del-Estero.d6097300.Vacation-Attraction) are a few of the most popular places to visit during your trip to Santiago del Estero. Stop dreaming and start adventuring. Check out the range of options on Expedia today and finally put your Santiago del Estero vacation plans into motion! ## Ready to book your vacation to Santiago del Estero? Choose your dates ## Santiago del Estero Hotel Deals ![NH Santiago del Estero](https://images.trvl-media.com/lodging/16000000/15360000/15358600/15358575/e46ad073_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### NH Santiago del Estero Independencia 110 Santiago del Estero Santiago del Estero Province Fully refundableReserve now, pay when you stay CA $102 CA $102 total May 2 - May 3 8.6/10 Excellent! (62 reviews) Located was great and the buffet breakfast offered a good variety, including healthy choices. However, the bathroom was uncomfortably small, with the door hitting the toilet, and it flooded during showers. Their advertised on-site PARKING IS MISLEADING since they DO NOT HAVE ANY PARKING on site; ... Reviewed on Jun 9, 2025 [](https://expedia.ca/Hotel-Search?startDate=02%2F05%2F2026&endDate=03%2F05%2F2026&selected=15358575&PinnedHotelID=15358575&HadPinnedHotel=true®ionId=3107) ![Hilton Garden Inn Santiago del Estero](https://images.trvl-media.com/lodging/71000000/70410000/70404500/70404433/36a2afd2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Garden Inn Santiago del Estero Leandro N Alem 148 Santiago del Estero Fully refundableReserve now, pay when you stay CA $154 CA $154 total Apr 3 - Apr 4 9.6/10 Exceptional! (44 reviews) All perfect Reviewed on Mar 15, 2026 [](https://expedia.ca/Hotel-Search?startDate=03%2F04%2F2026&endDate=04%2F04%2F2026&selected=70404433&PinnedHotelID=70404433&HadPinnedHotel=true®ionId=3107) ![HOTEL SOLANO](https://images.trvl-media.com/lodging/111000000/110990000/110986300/110986241/5b384531_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### HOTEL SOLANO 141 Sarmiento Santiago del Estero Santiago del Estero 2/10 (1 review) Vreselijk hotel De ontvangst was redelijk , wel jammer dat degene achter de balie geen woord Engels sprak. We kregen de sleutel en gingen naar onze kamer, het eerste wat opviel waren de knoppen in de lift, 1 daarvan hing aan een draad los. We opende de kamer en die was niet schoongemaakt handdoeken en dekbed lagen ... Reviewed on Feb 21, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=15%2F04%2F2026&endDate=16%2F04%2F2026&selected=110986241&PinnedHotelID=110986241&HadPinnedHotel=true®ionId=3107) [](https://expedia.ca/Hotel-Search?startDate=15%2F04%2F2026&endDate=16%2F04%2F2026&selected=110986241&PinnedHotelID=110986241&HadPinnedHotel=true®ionId=3107) [See all 20 properties in Santiago del Estero](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=02%2F04%2F2026&endDate=03%2F04%2F2026®ionId=3107) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app