Title: Book The Best Hotels in Santa María Mixtequilla for 2026 from CA $39 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Santa María Mixtequilla](https://expedia.ca/Santa-Maria-Mixtequilla-Vacation-Rentals.d553248635640631214.Travel-Guide-VacationRentals)[Santa María Mixtequilla Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Maria-Mixtequilla.d553248635640631214.Car-Rental-Guide)[Santa María Mixtequilla Vacation Packages](https://expedia.ca/Santa-Maria-Mixtequilla.d553248635640631214.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa María Mixtequilla Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Mar%C3%ADa+Mixtequilla%2C+Oaxaca%2C+Mexico®ionId=553248635640631214&latLong=16.424694%2C-95.275468&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Santa+Mar%C3%ADa+Mixtequilla%2C+Oaxaca%2C+Mexico®ionId=553248635640631214&latLong=16.424694%2C-95.275468&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=POOL) ## Check prices for these dates Tonight [Feb 26 - Feb 27](https://www.expedia.ca/Hotel-Search?regionId=553248635640631214&startDate=2026-02-26&endDate=2026-02-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 27 - Feb 28](https://www.expedia.ca/Hotel-Search?regionId=553248635640631214&startDate=2026-02-27&endDate=2026-02-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=553248635640631214&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=553248635640631214&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa María Mixtequilla hotels ![Outdoor pool](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/a2430bda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/e586f862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/c4ed54e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/68c7c09b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Majeva [](https://www.expedia.ca/Salina-Cruz-Hotels-Casa-Majeva.h102924009.Hotel-Information) Salina Cruz 10/10 Exceptional (3 reviews) "The property is truly a gem in quite a remote area. As it is a non season, everything is closed, but this hotel is working and that is nice. But actually besides its teritory there is nothing to do there. The owner is extremely nice and chatty! It gives property a lot if charm. Other staff members unfortunatelly really dont speak english much so the communication is very limited. Well, almost like in all Mexico. Overall nice pool and interior in the apartments, would be great to have some... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vismante CA $169 CA $201 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Salina-Cruz-Hotels-Casa-Majeva.h102924009.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/edb8d66f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/1aebd53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/5b276b7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/2f4a9613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Boutique Alebrijes Salina Cruz [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-Boutique-Alebrijes-Salina-Cruz.h96041351.Hotel-Information) Salina Cruz 9.4/10 Exceptional (19 reviews) "The room was clean and the housekeeping lady was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaymie CA $63 CA $75 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-Boutique-Alebrijes-Salina-Cruz.h96041351.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/3037610b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/c380db4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/e31980a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/be5c9146.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Calli [](https://www.expedia.ca/Tehuantepec-Hotels-Hotel-Calli.h41267126.Hotel-Information) Tehuantepec 9.0/10 Wonderful (91 reviews) "Comfortable, clean basic travel hotel. Grounds very nice, convenient restaurant." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) lois CA $86 CA $102 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Tehuantepec-Hotels-Hotel-Calli.h41267126.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/24544c31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/0ede6eaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/16007059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/64ccfc6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Express Inn Juchitan [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-HOTEL-EXPRESS-INN-JUCHITAN.h72665133.Hotel-Information) Juchitan de Zaragoza 7.8/10 Good (19 reviews) "Ok" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) obed [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-HOTEL-EXPRESS-INN-JUCHITAN.h72665133.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/d03a2093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/e8f5e91b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard view](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/51e62f1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/346b571c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Central [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-Hotel-Central.h42090604.Hotel-Information) Juchitan de Zaragoza 8.8/10 Excellent (93 reviews) "Perfect hotel!" ![Belgium](https://a.travel-assets.com/egds/marks/flags/be.svg) Lukas CA $62 CA $74 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-Hotel-Central.h42090604.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/5799af75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/b65f63ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/b597f045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 Queen Bed](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/f106e17f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### One Salina Cruz [](https://www.expedia.ca/Salina-Cruz-Hotels-One-Salina-Cruz.h6831542.Hotel-Information) Salina Cruz 9.0/10 Wonderful (448 reviews) "Room was comfortable. Good location. The breakfast was delicious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $68 CA $82 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/Salina-Cruz-Hotels-One-Salina-Cruz.h6831542.Hotel-Information) ![Comfort Double Room](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/2146269d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room | Terrace/patio](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/8d64d73b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/50ccf9ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/ecd5a57a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sicarú [](https://www.expedia.ca/Salina-Cruz-Hotels-Sicaru.h116224786.Hotel-Information) Salina Cruz 8.2/10 Very good (17 reviews) "Very clean, comfortable, and well located hotel in the heart of downtown Salina Cruz, Oaxaca, México. Nice price, very acceptable." ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) John CA $56 CA $66 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Salina-Cruz-Hotels-Sicaru.h116224786.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/ec7f1fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/a2433e02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/31f71865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/56bd3ee3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Salina Cruz [](https://www.expedia.ca/Salina-Cruz-Hotels-City-Express-Salina-Cruz.h6924397.Hotel-Information) Salina Cruz 8.4/10 Very good (315 reviews) "Excelente" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Yeeviani CA $76 CA $90 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Salina-Cruz-Hotels-City-Express-Salina-Cruz.h6924397.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/cde1bd71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/6f2141b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/bcaf11b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/5d29ebb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel De La Peña Inn [](https://www.expedia.ca/Tehuantepec-Hotels-Hotel-De-La-Pena-Inn.h33741125.Hotel-Information) Santa María 8.0/10 Very good (39 reviews) "Highly recommend this place for the price. Friendly professional staff. Clean room and super comfy bed. Nice bathroom. The location is a little odd being on a sort of roundabout, but as I was in town to visit the ruins of Guiengola it was ideal for me. Can't fault the plaxe " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Ralph [](https://www.expedia.ca/Tehuantepec-Hotels-Hotel-De-La-Pena-Inn.h33741125.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/5ec54c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/6df19f25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/e7389ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/b46429cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Calendas [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-Calendas.h48453285.Hotel-Information) Salina Cruz 7.8/10 Good (28 reviews) "The antique look and all the beautiful historical pictures" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Veronica [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-Calendas.h48453285.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/7e152f86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/2f37f228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/b919a617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/c7c02254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL CASA TERESA GALERIA CAFE [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-HOTEL-CASA-TERESA-GALERIA-CAFE.h96177046.Hotel-Information) Juchitan de Zaragoza 7.2/10 Good (18 reviews) "Very nice owners who helped us in many ways including personally driving us to the bus station when our taxi did not arrive on time to make sure we did not miss our bus to San Cristobal." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jeffrey [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-HOTEL-CASA-TERESA-GALERIA-CAFE.h96177046.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/b23d386b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room service - dining](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/612464fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/67afa004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/67a6a2d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Francisco [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-San-Francisco.h17760049.Hotel-Information) Salina Cruz 8.0/10 Very good (98 reviews) "One scorpion in the towel up my bed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mariano CA $70 CA $83 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-San-Francisco.h17760049.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/3cf748f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/79f72d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/0d8803a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/86f9fea7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Santa Cruz Juchitan [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-Hotel-Santa-Cruz-Juchitan.h32858642.Hotel-Information) Juchitan de Zaragoza 7.8/10 Good (119 reviews) "Being the only hotel in town, it was fine." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tony [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-Hotel-Santa-Cruz-Juchitan.h32858642.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/w6679h3456x0y0-1d009085.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/8e5dddc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/e9035ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/391ec38f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Express Inn Ixtepec [](https://www.expedia.ca/Ixtepec-Hotels-HOTEL-EXPRESS-INN-IXTEPEC.h78841413.Hotel-Information) Ixtepec 7.4/10 Good (56 reviews) "Express Inn is quiet , clean , and comfortable. The location is great for dining and shopping. A very fun little town " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tami [](https://www.expedia.ca/Ixtepec-Hotels-HOTEL-EXPRESS-INN-IXTEPEC.h78841413.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/f7f17fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 1 Double Bed, Non Smoking](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/df896580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 1 Double Bed, Non Smoking](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/4b8395c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 1 Double Bed, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/088f8af4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de Huéspedes Juanita [](https://www.expedia.ca/Salina-Cruz-Hotels-Casa-De-Huespedes-Juanita.h35253125.Hotel-Information) Salina Cruz 7.0/10 Good (18 reviews) "To rest its okay, there’s nothing to enjoy or feel surprised by the are. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juana CA $33 CA $39 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Salina-Cruz-Hotels-Casa-De-Huespedes-Juanita.h35253125.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36520000/36511300/36511274/caf80311.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite](https://images.trvl-media.com/lodging/37000000/36520000/36511300/36511274/6539d226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/37000000/36520000/36511300/36511274/9422b834.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36520000/36511300/36511274/b897d7e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gran Hotel Don Nacho [](https://www.expedia.ca/Salina-Cruz-Hotels-GRAN-HOTEL-DON-NACHO.h36511274.Hotel-Information) Salina Cruz 7.2/10 Good (27 reviews) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Javier CA $141 CA $167 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Salina-Cruz-Hotels-GRAN-HOTEL-DON-NACHO.h36511274.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-12&endDate=2026-03-13®ionId=553248635640631214&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=HTG_SPRING_PROMO_553248635640631214) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Mixtequilla-Hotels.d553248635640631214.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Mixtequilla-Hotels.d553248635640631214.Travel-Guide-Hotels) ## Top Santa María Mixtequilla Hotel Reviews ## Recent Reviews in Santa María Mixtequilla ![Casa de Huéspedes Juanita](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/f7f17fd6_y.jpg) ### Casa de Huéspedes Juanita 6/10 Okay "Staff was friendly, location close to the train station and not far from the zocalo Room itself had an ok size. However the integrated bathroom was not super great Shower and wall very low, which wasn’t pleasant as a tall person. And no warm water available. Which I at least didn’t see mentioned in the ad. " [](https://expedia.ca/Salina-Cruz-Hotels-Casa-De-Huespedes-Juanita.h35253125.Hotel-Information) ![One Salina Cruz](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/df2bb342_y.jpg) ### One Salina Cruz 10/10 Excellent "Room was comfortable. Good location. The breakfast was delicious. " [](https://expedia.ca/Salina-Cruz-Hotels-One-Salina-Cruz.h6831542.Hotel-Information) ![Hotel Boutique Alebrijes Salina Cruz](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/e2ed23a9_y.jpg) ### Hotel Boutique Alebrijes Salina Cruz 10/10 Excellent "Room, breakfast, staffs were good" [](https://expedia.ca/Salina-Cruz-Hotels-Hotel-Boutique-Alebrijes-Salina-Cruz.h96041351.Hotel-Information) ![Hotel Central](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/e8f5e91b_y.jpg) ### Hotel Central 10/10 Excellent "Perfect place to explore the city. " [](https://expedia.ca/Juchitan-De-Zaragoza-Hotels-Hotel-Central.h42090604.Hotel-Information) ![Hotel San Francisco](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/2a31ea42_y.jpg) ### Hotel San Francisco 8/10 Good "Room was a bit dated but clean and good value " [](https://expedia.ca/Salina-Cruz-Hotels-Hotel-San-Francisco.h17760049.Hotel-Information) ![Hotel De La Peña Inn](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/0dc628f7_y.jpg) ### Hotel De La Peña Inn 10/10 Excellent "Very clean. Spotless and pleasant service. " [](https://expedia.ca/Tehuantepec-Hotels-Hotel-De-La-Pena-Inn.h33741125.Hotel-Information) ![Hotel Calli](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/1cd94473_y.jpg) ### Hotel Calli 8/10 Good "Property was nice and well maintained. Nice outside pool. Breakfast was available for a price. " [](https://expedia.ca/Tehuantepec-Hotels-Hotel-Calli.h41267126.Hotel-Information) ![City Express by Marriott Salina Cruz](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/5fe44611_y.jpg) ### City Express by Marriott Salina Cruz 10/10 Excellent "Nice" [](https://expedia.ca/Salina-Cruz-Hotels-City-Express-Salina-Cruz.h6924397.Hotel-Information) ![Hotel Calendas](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/f38c2e2b_y.jpg) ### Hotel Calendas 10/10 Excellent "Me gusto el servicio del personal muy atentos, el lugar es muy tranquilony y centrico , pienso volver." [](https://expedia.ca/Salina-Cruz-Hotels-Hotel-Calendas.h48453285.Hotel-Information) ## More cheap stays in Santa María Mixtequilla ![Casa de Huéspedes Juanita](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/f7f17fd6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa de Huéspedes Juanita Tampico 80, Colonia Centro Salina Cruz OAX CA $33 CA $39 total Feb 27 - Feb 28 includes taxes & fees 7/10 Good! (18 reviews) [](https://expedia.ca/Salina-Cruz-Hotels-Casa-De-Huespedes-Juanita.h35253125.Hotel-Information) ![Sicarú](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/50ccf9ab_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sicarú 306 Av Manuel Ávila Camacho Santa Rosa Salina Cruz Oax. CA $56 CA $66 total Feb 27 - Feb 28 includes taxes & fees 8.2/10 Very Good! (17 reviews) [](https://expedia.ca/Salina-Cruz-Hotels-Sicaru.h116224786.Hotel-Information) ![Hotel San Francisco](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/2a31ea42_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel San Francisco Av. Manuel Avila Camacho 705 Salina Cruz OAX CA $70 CA $83 total Feb 27 - Feb 28 includes taxes & fees [](https://expedia.ca/Salina-Cruz-Hotels-Hotel-San-Francisco.h17760049.Hotel-Information) ![HOTEL PENÍNSULA Salina Cruz](https://images.trvl-media.com/lodging/93000000/92550000/92544600/92544516/2ba6f043_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL PENÍNSULA Salina Cruz 25 Transístmica Lomas de Galindo Salina Cruz Oax. [Get rates](https://expedia.ca/Hotel-Search?startDate=12%2F03%2F2026&endDate=13%2F03%2F2026&selected=92544516&PinnedHotelID=92544516&HadPinnedHotel=true®ionId=553248635640631214) 7.2/10 Good! (9 reviews) [](https://expedia.ca/Salina-Cruz-Hotels-PENINSULA-STAYS-Business-Hotel.h92544516.Hotel-Information) ![Hotel Express Inn Juchitan](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/4cdf3a6b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Express Inn Juchitan Prolongación 16 de septiembre Juchitan de Zaragoza OAX [Get rates](https://expedia.ca/Hotel-Search?startDate=12%2F03%2F2026&endDate=13%2F03%2F2026&selected=72665133&PinnedHotelID=72665133&HadPinnedHotel=true®ionId=553248635640631214) 7.8/10 Good! (19 reviews) [](https://expedia.ca/Juchitan-De-Zaragoza-Hotels-HOTEL-EXPRESS-INN-JUCHITAN.h72665133.Hotel-Information) ![Hotel Calendas](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/f38c2e2b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Calendas Avenida Puerto Angel No 408 Salina Cruz OAX [Get rates](https://expedia.ca/Hotel-Search?startDate=12%2F03%2F2026&endDate=13%2F03%2F2026&selected=48453285&PinnedHotelID=48453285&HadPinnedHotel=true®ionId=553248635640631214) 7.8/10 Good! (28 reviews) [](https://expedia.ca/Salina-Cruz-Hotels-Hotel-Calendas.h48453285.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Santa María Mixtequilla? > This area is the heart of Santa María Mixtequilla, offering convenient access to local amenities and cultural experiences. The Municipal Palace, a prominent landmark, is typically surrounded by small shops, eateries, and the local market. The streets here are generally easy to navigate on foot, allowing you to explore the local life at a relaxed pace. > > > Couples looking for an authentic and peaceful experience will find the town centre ideal. It offers a chance to experience the local culture directly, with opportunities to enjoy traditional Oaxacan cuisine at local restaurants and observe daily life in the plaza. The evenings here are usually quiet, great for a relaxing stay. > > > For travellers interested in local crafts and goods, staying near the market areas within the town centre is a good choice. ### When is the best time to go to Santa María Mixtequilla? > This period avoids the heavier rains of the wet season, which can make travel on unpaved roads more challenging. You'll find clear skies and comfortable temperatures, superb for exploring the region's natural beauty and archaeological sites. > > > For those interested in local culture and festivities, visiting in November allows you to experience Día de Muertos celebrations in nearby towns, offering a unique insight into Oaxacan traditions. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa María Mixtequilla hotel booking with Expedia? ### How much is the nightly rate at a Santa María Mixtequilla hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in Ixtepec ](https://www.expedia.ca/5Star-Ixtepec-Hotels.s50-0-d6344823.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Arrocito ](https://www.expedia.ca/Arrocito-Santa-Maria-Huatulco-Hotels-Luxury-Hotel.0-n910279673557200896-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Asuncion Ixtaltepec Hotels ](https://www.expedia.ca/Asuncion-Ixtaltepec-Hotels.d6354376.Travel-Guide-Hotels) - 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