Title: Book The Best Hotels in Santa María Mixtequilla for 2026 from CA $46 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Santa María Mixtequilla](https://expedia.ca/Santa-Maria-Mixtequilla-Vacation-Rentals.d553248635640631214.Travel-Guide-VacationRentals)[Santa María Mixtequilla Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Maria-Mixtequilla.d553248635640631214.Car-Rental-Guide)[Santa María Mixtequilla Vacation Packages](https://expedia.ca/Santa-Maria-Mixtequilla.d553248635640631214.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa María Mixtequilla from CA $46 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa María Mixtequilla Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Mar%C3%ADa+Mixtequilla%2C+Oaxaca%2C+Mexico®ionId=553248635640631214&latLong=16.424694%2C-95.275468&adults=2&startDate=2026-01-20&d1=2026-01-20&endDate=2026-01-22&d2=2026-01-22&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Santa+Mar%C3%ADa+Mixtequilla%2C+Oaxaca%2C+Mexico®ionId=553248635640631214&latLong=16.424694%2C-95.275468&adults=2&startDate=2026-01-20&d1=2026-01-20&endDate=2026-01-22&d2=2026-01-22&amenities=POOL) ## Check prices for these dates Tonight [Jan 6 - Jan 7](https://www.expedia.ca/Hotel-Search?regionId=553248635640631214&startDate=2026-01-06&endDate=2026-01-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 7 - Jan 8](https://www.expedia.ca/Hotel-Search?regionId=553248635640631214&startDate=2026-01-07&endDate=2026-01-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248635640631214&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=553248635640631214&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa María Mixtequilla hotels ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/7e152f86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/b919a617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/296760f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/2f37f228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL CASA TERESA GALERIA CAFE [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-HOTEL-CASA-TERESA-GALERIA-CAFE.h96177046.Hotel-Information) Juchitan de Zaragoza 7.2/10 Good (18) "Very nice owners who helped us in many ways including personally driving us to the bus station when our taxi did not arrive on time to make sure we did not miss our bus to San Cristobal." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jeffrey CA $62 CA $74 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-HOTEL-CASA-TERESA-GALERIA-CAFE.h96177046.Hotel-Information) ![Comfort Suite, Oceanfront (Escondido) | Terrace/patio](https://images.trvl-media.com/lodging/13000000/12950000/12947500/12947455/99df5002.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/13000000/12950000/12947500/12947455/905cb7ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Suite, Oceanfront (Escondido) | Beach/ocean view](https://images.trvl-media.com/lodging/13000000/12950000/12947500/12947455/dd508306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/13000000/12950000/12947500/12947455/90a8d4ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Punta Conejo Resort [](https://www.expedia.ca/Salina-Cruz-Hotels-Punta-Conejo-Resort.h12947455.Hotel-Information) Salina Cruz 7.2/10 Good (12) "If you want to get off the grid and feel isolated with ocean front accommodations, this is the spot . " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.ca/Salina-Cruz-Hotels-Punta-Conejo-Resort.h12947455.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/edb8d66f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/1aebd53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/5b276b7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | Private kitchen](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/5d81fb2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Boutique Alebrijes Salina Cruz [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-Boutique-Alebrijes-Salina-Cruz.h96041351.Hotel-Information) Salina Cruz 9.4/10 Exceptional (19) "The room was clean and the housekeeping lady was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaymie CA $61 CA $72 total includes taxes & fees Jan 8 - Jan 9 [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-Boutique-Alebrijes-Salina-Cruz.h96041351.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/cde1bd71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/5d29ebb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/bcaf11b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/06b49a98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel De La Peña Inn [](https://www.expedia.ca/Tehuantepec-Hotels-Hotel-De-La-Pena-Inn.h33741125.Hotel-Information) Santa María 8.2/10 Very good (37) "Highly recommend this place for the price. Friendly professional staff. Clean room and super comfy bed. Nice bathroom. The location is a little odd being on a sort of roundabout, but as I was in town to visit the ruins of Guiengola it was ideal for me. Can't fault the plaxe " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Ralph CA $49 CA $58 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Tehuantepec-Hotels-Hotel-De-La-Pena-Inn.h33741125.Hotel-Information) ![40-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/103000000/102980000/102977600/102977536/0b4d9f65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/103000000/102980000/102977600/102977536/32810030.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/103000000/102980000/102977600/102977536/c18138d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/103000000/102980000/102977600/102977536/a8bde402.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bungalows Punta Conejo [](https://www.expedia.ca/Salina-Cruz-Hotels-Bungalows-Punta-Conejo.h102977536.Hotel-Information) Salina Cruz 9.2/10 Wonderful (10) "The shower had a very bad water flow. When we arrived, there were no towels and toilet-paper in the room. At the end we could almost not pay with our creditcard (raison ??) But the breakfast was very good! Thank you" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Hans CA $69 CA $82 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Salina-Cruz-Hotels-Bungalows-Punta-Conejo.h102977536.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/f7f17fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 1 Double Bed, Non Smoking](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/df896580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 1 Double Bed, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/025cdb79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 1 Double Bed, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/088f8af4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de Huéspedes Juanita [](https://www.expedia.ca/Salina-Cruz-Hotels-Casa-De-Huespedes-Juanita.h35253125.Hotel-Information) Salina Cruz 7.2/10 Good (17) "To rest its okay, there’s nothing to enjoy or feel surprised by the are. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juana CA $38 CA $46 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Salina-Cruz-Hotels-Casa-De-Huespedes-Juanita.h35253125.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/3cf748f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/0d8803a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/6e2f852a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/79f72d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Santa Cruz Juchitan [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-Hotel-Santa-Cruz-Juchitan.h32858642.Hotel-Information) Juchitan de Zaragoza 7.8/10 Good (114) "Being the only hotel in town, it was fine." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tony CA $55 CA $65 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-Hotel-Santa-Cruz-Juchitan.h32858642.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/d03a2093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/346b571c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard view](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/51e62f1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/c7cf8151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Central [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-Hotel-Central.h42090604.Hotel-Information) Juchitan de Zaragoza 8.6/10 Excellent (91) "Perfect hotel!" ![Belgium](https://a.travel-assets.com/egds/marks/flags/be.svg) Lukas CA $60 CA $71 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-Hotel-Central.h42090604.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/3037610b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/c380db4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/e31980a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/a2110175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Calli [](https://www.expedia.ca/Tehuantepec-Hotels-Hotel-Calli.h41267126.Hotel-Information) Tehuantepec 9.0/10 Wonderful (90) "Comfortable, clean basic travel hotel. Grounds very nice, convenient restaurant." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) lois CA $76 CA $90 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Tehuantepec-Hotels-Hotel-Calli.h41267126.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/24544c31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/64ccfc6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/16007059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/0ede6eaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Express Inn Juchitan [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-HOTEL-EXPRESS-INN-JUCHITAN.h72665133.Hotel-Information) Juchitan de Zaragoza 7.8/10 Good (19) "Ok" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) obed [](https://www.expedia.ca/Juchitan-De-Zaragoza-Hotels-HOTEL-EXPRESS-INN-JUCHITAN.h72665133.Hotel-Information) ![Comfort Double Room](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/2146269d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room | Terrace/patio](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/8d64d73b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/ecd5a57a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/50ccf9ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sicarú [](https://www.expedia.ca/Salina-Cruz-Hotels-Sicaru.h116224786.Hotel-Information) Salina Cruz 8.2/10 Very good (17) "Very clean, comfortable, and well located hotel in the heart of downtown Salina Cruz, Oaxaca, México. Nice price, very acceptable." ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) John CA $54 CA $64 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Salina-Cruz-Hotels-Sicaru.h116224786.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/5ec54c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/983e97bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/6df19f25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/e7389ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Calendas [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-Calendas.h48453285.Hotel-Information) Salina Cruz 7.8/10 Good (27) "The antique look and all the beautiful historical pictures" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Veronica [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-Calendas.h48453285.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/w6679h3456x0y0-1d009085.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/w1414h1998x0y0-54c0384d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/e9035ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/8e5dddc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Express Inn Ixtepec [](https://www.expedia.ca/Ixtepec-Hotels-HOTEL-EXPRESS-INN-IXTEPEC.h78841413.Hotel-Information) Ixtepec 7.4/10 Good (54) "Express Inn is quiet , clean , and comfortable. The location is great for dining and shopping. A very fun little town " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tami CA $73 CA $86 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Ixtepec-Hotels-HOTEL-EXPRESS-INN-IXTEPEC.h78841413.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/5799af75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/b65f63ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/b597f045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/3264406c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### One Salina Cruz [](https://www.expedia.ca/Salina-Cruz-Hotels-One-Salina-Cruz.h6831542.Hotel-Information) Salina Cruz 9.0/10 Wonderful (427) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Elizabeth Yazmin CA $71 CA $85 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Salina-Cruz-Hotels-One-Salina-Cruz.h6831542.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/a2430bda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/68c7c09b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/c4ed54e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/b22eade5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Majeva [](https://www.expedia.ca/Salina-Cruz-Hotels-Casa-Majeva.h102924009.Hotel-Information) Salina Cruz 10/10 Exceptional (3) "The property is truly a gem in quite a remote area. As it is a non season, everything is closed, but this hotel is working and that is nice. But actually besides its teritory there is nothing to do there. The owner is extremely nice and chatty! It gives property a lot if charm. Other staff members unfortunatelly really dont speak english much so the communication is very limited. Well, almost like in all Mexico. Overall nice pool and interior in the apartments, would be great to have some... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vismante CA $163 CA $194 total includes taxes & fees Jan 10 - Jan 11 [](https://www.expedia.ca/Salina-Cruz-Hotels-Casa-Majeva.h102924009.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/b23d386b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/5da47f5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/67afa004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room service - dining](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/612464fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Francisco [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-San-Francisco.h17760049.Hotel-Information) Salina Cruz 8.0/10 Very good (96) "One scorpion in the towel up my bed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mariano CA $67 CA $80 total includes taxes & fees Jan 23 - Jan 24 [](https://www.expedia.ca/Salina-Cruz-Hotels-Hotel-San-Francisco.h17760049.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36520000/36511300/36511274/caf80311.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/37000000/36520000/36511300/36511274/9422b834.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36520000/36511300/36511274/b897d7e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/37000000/36520000/36511300/36511274/6a3b0846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gran Hotel Don Nacho [](https://www.expedia.ca/Salina-Cruz-Hotels-GRAN-HOTEL-DON-NACHO.h36511274.Hotel-Information) Salina Cruz 7.2/10 Good (27) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Javier CA $123 CA $146 total includes taxes & fees Jan 10 - Jan 11 [](https://www.expedia.ca/Salina-Cruz-Hotels-GRAN-HOTEL-DON-NACHO.h36511274.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/ec7f1fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/56bd3ee3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/w3995h2663x5y0-25fa52c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/31f71865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Salina Cruz [](https://www.expedia.ca/Salina-Cruz-Hotels-City-Express-Salina-Cruz.h6924397.Hotel-Information) Salina Cruz 8.4/10 Very good (310) "Excelente" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Yeeviani CA $80 CA $95 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Salina-Cruz-Hotels-City-Express-Salina-Cruz.h6924397.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-20&endDate=2026-01-21®ionId=553248635640631214&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Mixtequilla-Hotels.d553248635640631214.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Mixtequilla-Hotels.d553248635640631214.Travel-Guide-Hotels) ## More cheap stays in Santa María Mixtequilla ![Casa de Huéspedes Juanita](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/f7f17fd6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa de Huéspedes Juanita Tampico 80, Colonia Centro Salina Cruz OAX CA $38 CA $46 total Jan 7 - Jan 8 includes taxes & fees 7/10 Good! (17 reviews) [](https://expedia.ca/Salina-Cruz-Hotels-Casa-De-Huespedes-Juanita.h35253125.Hotel-Information) ![Sicarú](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/50ccf9ab_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sicarú 306 Av Manuel Ávila Camacho Santa Rosa Salina Cruz Oax. CA $54 CA $64 total Jan 7 - Jan 8 includes taxes & fees 8.2/10 Very Good! (17 reviews) [](https://expedia.ca/Salina-Cruz-Hotels-Sicaru.h116224786.Hotel-Information) ![Hotel San Francisco](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/2a31ea42_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel San Francisco Av. Manuel Avila Camacho 705 Salina Cruz OAX CA $67 CA $80 total Jan 23 - Jan 24 includes taxes & fees 7.8/10 Good! (96 reviews) [](https://expedia.ca/Salina-Cruz-Hotels-Hotel-San-Francisco.h17760049.Hotel-Information) ![HOTEL PENÍNSULA Salina Cruz](https://images.trvl-media.com/lodging/93000000/92550000/92544600/92544516/2ba6f043_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL PENÍNSULA Salina Cruz 25 Transístmica Lomas de Galindo Salina Cruz Oax. [Get rates](https://expedia.ca/Hotel-Search?startDate=20%2F01%2F2026&endDate=21%2F01%2F2026&selected=92544516&PinnedHotelID=92544516&HadPinnedHotel=true®ionId=553248635640631214) 7.2/10 Good! (9 reviews) [](https://expedia.ca/Salina-Cruz-Hotels-PENINSULA-STAYS-Business-Hotel.h92544516.Hotel-Information) ![Hotel Express Inn Juchitan](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/4cdf3a6b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Express Inn Juchitan Prolongación 16 de septiembre Juchitan de Zaragoza OAX [Get rates](https://expedia.ca/Hotel-Search?startDate=20%2F01%2F2026&endDate=21%2F01%2F2026&selected=72665133&PinnedHotelID=72665133&HadPinnedHotel=true®ionId=553248635640631214) 7.6/10 Good! (19 reviews) [](https://expedia.ca/Juchitan-De-Zaragoza-Hotels-HOTEL-EXPRESS-INN-JUCHITAN.h72665133.Hotel-Information) ![Hotel Calendas](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/f38c2e2b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Calendas Avenida Puerto Angel No 408 Salina Cruz OAX [Get rates](https://expedia.ca/Hotel-Search?startDate=20%2F01%2F2026&endDate=21%2F01%2F2026&selected=48453285&PinnedHotelID=48453285&HadPinnedHotel=true®ionId=553248635640631214) 7.8/10 Good! (27 reviews) [](https://expedia.ca/Salina-Cruz-Hotels-Hotel-Calendas.h48453285.Hotel-Information) ## Recent reviews of Santa María Mixtequilla hotels ![Hotel Boutique Alebrijes Salina Cruz](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/e2ed23a9_y.jpg) ### Hotel Boutique Alebrijes Salina Cruz 5/5 Excellent "Room, breakfast, staffs were good" A verified traveller stayed at Hotel Boutique Alebrijes Salina Cruz Posted 2 days ago [](https://expedia.ca/Salina-Cruz-Hotels-Hotel-Boutique-Alebrijes-Salina-Cruz.h96041351.Hotel-Information) ![Hotel Central](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/e8f5e91b_y.jpg) ### Hotel Central 5/5 Excellent "Perfect place to explore the city. " A verified traveller stayed at Hotel Central Posted 12 days ago [](https://expedia.ca/Juchitan-De-Zaragoza-Hotels-Hotel-Central.h42090604.Hotel-Information) ![Hotel San Francisco](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/2a31ea42_y.jpg) ### Hotel San Francisco 4/5 Good "Room was a bit dated but clean and good value " A verified traveller stayed at Hotel San Francisco Posted 3 weeks ago [](https://expedia.ca/Salina-Cruz-Hotels-Hotel-San-Francisco.h17760049.Hotel-Information) ![Sicarú](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/50ccf9ab_y.jpg) ### Sicarú 5/5 Excellent "Toda bien " A verified traveller from Temecula stayed at Sicarú Posted 2 months ago [](https://expedia.ca/Salina-Cruz-Hotels-Sicaru.h116224786.Hotel-Information) ![Hotel De La Peña Inn](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/0dc628f7_y.jpg) ### Hotel De La Peña Inn 5/5 Excellent "Very clean. Spotless and pleasant service. " A verified traveller stayed at Hotel De La Peña Inn Posted 3 months ago [](https://expedia.ca/Tehuantepec-Hotels-Hotel-De-La-Pena-Inn.h33741125.Hotel-Information) ![One Salina Cruz](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/df2bb342_y.jpg) ### One Salina Cruz 5/5 Excellent "Conveniente laundry " A verified traveller stayed at One Salina Cruz Posted 4 months ago [](https://expedia.ca/Salina-Cruz-Hotels-One-Salina-Cruz.h6831542.Hotel-Information) ![Casa de Huéspedes Juanita](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/f7f17fd6_y.jpg) ### Casa de Huéspedes Juanita 3/5 Okay "To rest its okay, there’s nothing to enjoy or feel surprised by the are. " A verified traveller stayed at Casa de Huéspedes Juanita Posted 6 months ago [](https://expedia.ca/Salina-Cruz-Hotels-Casa-De-Huespedes-Juanita.h35253125.Hotel-Information) ![City Express by Marriott Salina Cruz](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/5fe44611_y.jpg) ### City Express by Marriott Salina Cruz 5/5 Excellent "Nice" A verified traveller stayed at City Express by Marriott Salina Cruz Posted 7 months ago [](https://expedia.ca/Salina-Cruz-Hotels-City-Express-Salina-Cruz.h6924397.Hotel-Information) ![Hotel Calendas](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/f38c2e2b_y.jpg) ### Hotel Calendas 5/5 Excellent "Me gusto el servicio del personal muy atentos, el lugar es muy tranquilony y centrico , pienso volver." A verified traveller stayed at Hotel Calendas Posted 10 months ago [](https://expedia.ca/Salina-Cruz-Hotels-Hotel-Calendas.h48453285.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in Santa María Mixtequilla? ### What are some of the best vacation rentals in Santa María Mixtequilla? ### If I need to cancel my hotel reservation in Santa María Mixtequilla, will I receive a refund? ### What is staying in Santa María Mixtequilla like? ### What are the top places to visit in Santa María Mixtequilla? ### What's the seasonal weather like in Santa María Mixtequilla? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [5 Star Hotels in Ixtepec ](https://www.expedia.ca/5Star-Ixtepec-Hotels.s50-0-d6344823.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Arrocito ](https://www.expedia.ca/Arrocito-Santa-Maria-Huatulco-Hotels-Luxury-Hotel.0-n910279673557200896-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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