Title: Book The Best Hotels in Santa Isabel for 2025 from CA $146 - Competitive Prices - Expedia.ca [Vacation Rentals in Santa Isabel](https://expedia.ca/Santa-Isabel-Vacation-Rentals.d553248635923647964.Travel-Guide-VacationRentals)[Santa Isabel Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Isabel.d553248635923647964.Car-Rental-Guide)[Santa Isabel Vacation Packages](https://expedia.ca/Santa-Isabel.d553248635923647964.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa Isabel from CA $146 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 9 - Nov 10](https://www.expedia.ca/Hotel-Search?regionId=553248635923647964&startDate=2025-11-09&endDate=2025-11-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 10 - Nov 11](https://www.expedia.ca/Hotel-Search?regionId=553248635923647964&startDate=2025-11-10&endDate=2025-11-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635923647964&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248635923647964&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 2 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Exterior](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462594/ec603687.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462594/d239c516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462594/b8987119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462594/45ae978d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Melincue Casino & Resort Melincué 8.0/10 Very good (4) "Lugar tranquilo " ![Argentina](https://a.travel-assets.com/egds/marks/flags/ar.svg) Gustavo CA $146 CA $146 total Nov 16 - Nov 17 [](https://www.expedia.ca/Melincue-Hotels-Melincue-Casino-Resort.h15462594.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-23&endDate=2025-11-24®ionId=553248635923647964&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d553248635923647964.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d553248635923647964.Travel-Guide-Hotels) ## More cheap stays in Santa Isabel ![Edificio HEOL](https://images.trvl-media.com/lodging/34000000/33800000/33794300/33794226/1c125f84_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Edificio HEOL Pellegrini 1155, Venado Tuerto, Santa Fe [Get rates](https://expedia.ca/Hotel-Search?startDate=23%2F11%2F2025&endDate=24%2F11%2F2025&selected=33794226&PinnedHotelID=33794226&HadPinnedHotel=true®ionId=553248635923647964) [](https://expedia.ca/Venado-Tuerto-Hotels-Edificio-HEOL.h33794226.Hotel-Information) ## Frequently asked questions ### What's the best place for a stay in Santa Isabel? > [Melincue Casino & Resort](https://www.expedia.ca/Melincue-Hotels-Melincue-Casino-Resort.h15462594.Hotel-Information), located 23.3 mi (37.5 km) from the heart of Santa Isabel, is a top choice for your stay based on our traveler data. [Edificio HEOL](https://www.expedia.ca/Venado-Tuerto-Hotels-Edificio-HEOL.h33794226.Hotel-Information) is another good option for your trip to the area. See all available [top hotels](https://www.expedia.ca/Hotel-Search?regionId=553248635923647964), or [vacation rentals in Santa Isabel](https://www.expedia.ca/Santa-Isabel-Vacation-Rentals.d553248635923647964.Travel-Guide-VacationRentals). ### If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund? > Yes, most hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by [fully refundable](https://www.expedia.ca/Hotel-Search?regionId=553248635923647964&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Santa Isabel. ### What is staying in Santa Isabel like? > Visitors to Santa Isabel are sure to find plenty to explore and enjoy. There are 2 hotels and other accommodations in the surrounding area. Find out more about [Santa Isabel](https://www.expedia.ca/Santa-Isabel.dx553248635923647964). ### What's the seasonal weather like in Santa Isabel? > The hottest months are usually January and December with an average temp of 74°F, while the coldest months are July and June with an average of 54°F. 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)