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Oct 16 - Oct 17
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Oct 17 - Oct 18
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Oct 16 - Oct 18
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Oct 23 - Oct 25

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Our top choices for Santa Cruz hotels

A reception area with a counter, pendant lights, a plant, and a glass wall.
A hotel room with two beds, a desk, a chair, a TV, and a large window with a city view.
A modern cafeteria with white tables and chairs, large windows with a view of greenery, and a counter with beverages.
A multi-story hotel with a flat facade, a sign reading 'CITY EXPRESS,' and a parking lot.

1. City Express by Marriott Cananea

City Express by Marriott Cananea
Cananea
United States
Erika
CA $105
CA $117 total
includes taxes & fees
Nov 1 - Nov 2
City Express by Marriott Cananea
A modern hotel lobby with a reception desk, seating area, and large windows offering a city view.
A modern bar area with wooden chairs, a flat-screen TV, and pendant lighting.
A modern hotel room with a dining area, a kitchen counter with breakfast items, and a large fruit-themed mural on the wall.
A hotel room with two beds, a desk, a TV, and a view of the outdoors.

2. Fairfield Inn & Suites by Marriott Nogales

Fairfield Inn & Suites by Marriott Nogales
Nogales
United States
David
CA $180
CA $200 total
includes taxes & fees
Oct 24 - Oct 25
Fairfield Inn & Suites by Marriott Nogales
A cozy living room with a sofa, ottoman, and round coffee table, surrounded by potted plants and a mounted deer head.
A grand chandelier, a mirror, and a painting in a room with a wooden bench.
A restaurant with a cozy seating area, including a striped booth and tables with candles and flowers.
A spacious room with a high ceiling, wooden beams, and a stone fireplace. There are several chairs and a small table, along with potted plants on a counter.

3. Hotel Fray Marcos

Hotel Fray Marcos
Centro
United States
Daniel
CA $119
CA $132 total
includes taxes & fees
Oct 26 - Oct 27
Hotel Fray Marcos
A building with a reception area and a staircase leading up to it.
A modern waiting area with two black leather sofas, a glass coffee table, and a large framed artwork on the wall.
A reception desk with a glass partition, a digital welcome screen displaying multiple languages, and a clean, modern interior with a tiled floor.
A multi-story hotel with balconies, a covered walkway, and a landscaped area with plants.

4. Hotel Marques De Cima

Hotel Marques De Cima
Nogales
United States
martin
CA $122
CA $137 total
includes taxes & fees
Oct 30 - Oct 31
Hotel Marques De Cima
A pathway flanked by neatly trimmed hedges and palm trees, leading to a building with a modern design and a red and blue sign.
A bar area with a TV, shelves of liquor, and a food display.
A courtyard with a pool, palm trees, and outdoor seating.
A spacious dining area with multiple tables and chairs, large windows offering views of the outdoors, and a modern ceiling design with hanging lights.

5. Fiesta Inn Nogales

Fiesta Inn Nogales
Nueva Nogales
United States
Mario
CA $131
CA $155 total
includes taxes & fees
Nov 2 - Nov 3
Fiesta Inn Nogales
A bedroom with two beds, a wardrobe, and a door.
A modern building with a large window and a fire extinguisher mounted on the wall.
A building with a large garage entrance, a fire extinguisher, and a small window with a curtain.
A bathroom with a glass bowl sink, white towels, and a mirror reflecting the room.

6. Hotel Pedregal

Hotel Pedregal
Colinas del Yaqui
United States
Idaliee
CA $111
CA $132 total
includes taxes & fees
Oct 28 - Oct 29
Hotel Pedregal
A restaurant interior with booths, tables, and chairs.
A multi-story motel with a sign reading 'Motel San Luis de Nogales.'
A multi-story residential building with balconies, a covered walkway, and a green hedge.
A bathroom with a white sink, mirror, and toilet.

7. Motel San Luis de Nogales

Motel San Luis de Nogales
Centro
United States
Priscilla
CA $72
CA $85 total
includes taxes & fees
Oct 18 - Oct 19
Motel San Luis de Nogales
A bedroom with a bed, a ceiling fan, a bedside lamp, and a window with blinds.
A modern meeting room with a round table, grey chairs, a sofa, and a ceiling fan.
A modern bathroom with a glass-enclosed shower, a toilet, and a sink.
A modern living room with a blue sofa, a wooden dining table with black chairs, a flat-screen TV mounted on the wall, and a ceiling fan.

8. Departamento Kennedy Nogales

Departamento Kennedy Nogales
Kennedy
CA $162
CA $192 total
includes taxes & fees
Oct 18 - Oct 19
Departamento Kennedy Nogales
A modern lobby with a reception desk, seating area, and large windows offering a view of the outside.
A modern living room with a grey sofa, two armchairs, a coffee table with a flower vase, and two ottomans.
A CityExpress hotel with a modern design, featuring a flat facade, multiple windows, and a covered entrance.
A hotel room with two beds, a desk, a chair, and a TV.

9. City Express by Marriott Nogales

City Express by Marriott Nogales
Nueva Nogales
United States
Carlos
CA $126
CA $140 total
includes taxes & fees
Nov 6 - Nov 7
City Express by Marriott Nogales
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Top Santa Cruz Hotel Reviews

Hotel Marques De Cima

Hotel Marques De Cima

8/10 Good
"Buen hotel cumple con lo necesario para pasar la noche"
Victor 1-night trip
Posted 2 days ago
Hotel Marques De Cima
Fairfield Inn & Suites by Marriott Nogales

Fairfield Inn & Suites by Marriott Nogales

8/10 Good
"The bathroom and floors were not clean. The bed was hard to sleep on. The walls and floors are thin, making it hard to sleep because of all the noises. The location was nice and the view was good."
Tuan 1-night trip
Posted 5 days ago
Fairfield Inn & Suites by Marriott Nogales
Hotel Pedregal

Hotel Pedregal

10/10 Excellent
"Everyone has a small garage. All night security. Clean room. Hot water. Many stores, snacks and food in the area. Ac is cold."
Fabian 1-night trip
Posted 2 weeks ago
Hotel Pedregal
City Express by Marriott Cananea

City Express by Marriott Cananea

10/10 Excellent
"Clean room and very friendly staff."
Erika 1-night trip
Posted 1 month ago
City Express by Marriott Cananea
Motel San Luis de Nogales

Motel San Luis de Nogales

10/10 Excellent
"The view is nice.A lot of stores around you a great restaurant downstairs. Kid friendly too."
Priscilla 2-night trip
Posted 3 months ago
Motel San Luis de Nogales
Charming 2-bedroom house with WiFi, AC in beautiful Cananea

Charming 2-bedroom house with WiFi, AC in beautiful Cananea

10/10 Excellent
"Nice place. Very friendly and helpful host. Thank you."
Kendall 3-night trip
Posted 5 months ago
Charming 2-bedroom house with WiFi, AC in beautiful Cananea

More cheap stays in Santa Cruz

Hotel Pedregal

Hotel Pedregal

Av. del Yaqui Colinas del Yaqui Nogales Son.
CA $111
CA $132 total
Oct 28 - Oct 29
includes taxes & fees
8.2/10 Very good! (64 reviews)
Hotel Pedregal
Hotel Marques De Cima

Hotel Marques De Cima

Av. Alvaro Obregon # 2024 Nogales SON
CA $122
CA $137 total
Oct 30 - Oct 31
includes taxes & fees
8.6/10 Excellent! (923 reviews)
Hotel Marques De Cima
Departamento Kennedy Nogales

Departamento Kennedy Nogales

29 Navojoa Nogales Son.
CA $162
CA $192 total
Oct 18 - Oct 19
includes taxes & fees
Departamento Kennedy Nogales
Hotel Plaza Nogales

Hotel Plaza Nogales

Prolongacion Av.Alvaro Obregon 4190 Col. Nuevo Nogales Nogales SON
Get ratesHotel Plaza Nogales

Frequently asked questions

What is the best area to stay in Santa Cruz?
The best area to stay in Santa Cruz, Sonora, is the town centre, particularly around the main square, Plaza Zaragoza.This area is the heart of Santa Cruz, offering a convenient base for exploring. You'll find many of the town's key landmarks, including the historic Templo de Nuestra Señora de Guadalupe, within easy walking distance. The streets here are generally well-maintained and offer a pleasant stroll amongst local shops and eateries.Couples looking for a relaxed and authentic experience will find the town centre ideal. It provides opportunities to enjoy local cuisine, browse artisan crafts, and simply soak in the local way of life without needing to travel far. The evenings around Plaza Zaragoza often feature local gatherings, adding to the pleasant atmosphere.
When is the best time to go to Santa Cruz?
The best time to visit Santa Cruz, Sonora, Mexico is during the cooler, drier months from November to April.During this period, the weather is pleasantly warm with average temperatures ranging from 20°C to 28°C, and there's very little rainfall. This makes it ideal for exploring the outdoors, whether you're interested in hiking the Sierra Azul mountains or enjoying the local markets without the intense heat of summer.Couples looking for a relaxed getaway will appreciate the comfortable climate for leisurely strolls through the town's historic centre, perhaps visiting the Mission de Santa Cruz. The evenings are mild, superb for dining al fresco.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.
How much is the nightly rate at a Santa Cruz hotel?
Prices for hotels in Santa Cruz often vary, but you can find a great deal from CA $85 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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