A coastal fortification with a lighthouse, rocky hills, and clear blue sea.

Hotels in Santa Ana, Cartagena

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Check prices for these dates

This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

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Our top choices for Santa Ana hotels

A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted TV.

1. Posadas de España Cartagena

Posadas de España Cartagena
3.5 star property
Hondón, 7.3 km from Santa Ana
8.8 out of 10, Excellent, (430 reviews)
"Great place to stay!"
United States
Gary
The price is CA $101
CA $111 total
includes taxes & fees
Nov 2 - Nov 3
Posadas de España Cartagena
A modern bar area with a light wood finish, a coffee machine, and three bar stools.

2. NH Campo Cartagena

NH Campo Cartagena
3.0 star property
Cartagena Casco, 6.9 km from Santa Ana
8.8 out of 10, Excellent, (496 reviews)
"very helpful and friendly staff. very clean rooms; great breakfast and very appealing place."
United States
Martha
The price is CA $93
CA $103 total
includes taxes & fees
Nov 1 - Nov 2
NH Campo Cartagena
A hotel entrance with a reception desk, seating area, and potted plants.

3. Hotel Sercotel Carlos III

Hotel Sercotel Carlos III
3.0 star property
Casco Antiguo, 7.4 km from Santa Ana
9.0 out of 10, Wonderful, (664 reviews)
"It was a good stay overall"
United Kingdom
Patricia
The price is CA $92
CA $102 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Sercotel Carlos III
A hotel lobby with a reception desk, seating area, and a large skylight.

4. Hotel Manolo

Hotel Manolo
3.0 star property
San Antonio Abad, 5.3 km from Santa Ana
7.8 out of 10, Good, (136 reviews)
"Good central location with free parking"
United Kingdom
Alan
The price is CA $98
CA $107 total
includes taxes & fees
Nov 5 - Nov 6
Hotel Manolo
A grand staircase with a chandelier, a wall with a building mural, and a modern interior design.

5. Hotel Sercotel Alfonso XIII

Hotel Sercotel Alfonso XIII
4.0 star property
Casco Antiguo, 7.3 km from Santa Ana
9.0 out of 10, Wonderful, (361 reviews)
"The location was great for exploring the city"
New Zealand
Craig
The price is CA $120
CA $132 total
includes taxes & fees
Oct 13 - Oct 14
Hotel Sercotel Alfonso XIII
A hotel room with a large bed, a desk, a flat-screen TV, a coffee maker, and a window with curtains.

6. B&B Hotel Cartagena Cartagonova

B&B Hotel Cartagena Cartagonova
4.0 star property
Casco Antiguo, 7.4 km from Santa Ana
8.0 out of 10, Very good, (184 reviews)
"Staff super friendly and helpful. Great location and good rooms, especially for the price."
United Kingdom
Linda
The price is CA $85
CA $94 total
includes taxes & fees
Oct 18 - Oct 19
B&B Hotel Cartagena Cartagonova
A hotel with a modern facade, a classical building with a dome in the background, and a well-lit entrance.

7. AC Hotel Cartagena

AC Hotel Cartagena
4.0 star property
Casco Antiguo, 8.1 km from Santa Ana
9.6 out of 10, Exceptional, (119 reviews)
"Excellent location in the middle of everything. Breakfast was good but could improve. Parking on property was a plus"
United States
Eduardo
The price is CA $177
CA $195 total
includes taxes & fees
Oct 18 - Oct 19
AC Hotel Cartagena
A view from a balcony with a wrought iron railing, overlooking ancient ruins and a grassy area.

8. Apartamentos turísticos Teatro Romano

Apartamentos turísticos Teatro Romano
2.0 star property
Casco Antiguo, 8 km from Santa Ana
7.8 out of 10, Good, (10 reviews)
"A lovely big apartment in a great location. Not suitable for suitcases so we left our big bags in carpark as we were only staying one night. View of Roman theatre great. Room was clean but almost no provisions like water, tea, milk and shampoo. Come prepared! "
United Kingdom
Dani
The price is CA $105
CA $105 total
includes taxes & fees
Oct 6 - Oct 7
Apartamentos turísticos Teatro Romano
A bedroom with a bed, curtains, a TV, and a view of the outside.

9. La Casa de las Flores

La Casa de las Flores
3.0 star property
Casco Antiguo, 7.8 km from Santa Ana
9.6 out of 10, Exceptional, (15 reviews)
"Great location and lovely rooms with everything we needed. Would have been good to have somewhere to hang the clothes we washed"
United Kingdom
Emily
The price is CA $200
CA $220 total
includes taxes & fees
Nov 4 - Nov 5
La Casa de las Flores
A swimming pool with a surrounding walkway, palm trees, and a sunset sky.

10. Espacio Finca Alegría

Espacio Finca Alegría
3.0 star property
Perín, 8 km from Santa Ana
8.0 out of 10, Very good, (14 reviews)
"Personnel aimable. Chambre propre avec serviettes de toilette. Le plus : la petite cuisine commune et la piscine. Le moins: avoir un ronfleur dans la chambre en face ! 😁. Mais l'ensemble est très correct. Je recommande."
Spain
BALA
The price is CA $81
CA $89 total
includes taxes & fees
Oct 15 - Oct 16
Espacio Finca Alegría
A modern living room with a grey sofa, a round coffee table, and a dining area with a white table and chairs.

11. Apartamentos Plaza Sevillano

Apartamentos Plaza Sevillano
2.0 star property
Casco Antiguo, 7.6 km from Santa Ana
9.4 out of 10, Exceptional, (12 reviews)
"Excellent location, easy access, spacious, clean, beautiful views and the accommodations were great. "
United States
Betty
The price is CA $106
CA $106 total
includes taxes & fees
Oct 6 - Oct 7
Apartamentos Plaza Sevillano
A room with a laptop on a round table, a TV mounted on the wall, and a potted plant.

12. Apartamentos Turísticos Plaza del Rey

Apartamentos Turísticos Plaza del Rey
4.0 star property
Casco Antiguo, 7.9 km from Santa Ana
9.2 out of 10, Wonderful, (21 reviews)
"Amazing location and apartment. Highly recommend."
Canada
Ivan
The price is CA $97
CA $106 total
includes taxes & fees
Oct 12 - Oct 13
Apartamentos Turísticos Plaza del Rey
A modern building with unique geometric architecture, featuring balconies and patterned facades.

13. Loop INN Hostel Cartagena

Loop INN Hostel Cartagena
2.0 star property
Casco Antiguo, 7.8 km from Santa Ana
9.0 out of 10, Wonderful, (157 reviews)
"It's a nice, clean basic hotel close to the town centre. It's also good value"
United States
STEPHEN
The price is CA $69
CA $76 total
includes taxes & fees
Nov 4 - Nov 5
Loop INN Hostel Cartagena
A hallway with a stone wall, a wooden door, and a white tiled floor.

14. Apartamentos Turísticos Insulae

Apartamentos Turísticos Insulae
3.0 star property
Casco Antiguo, 7.9 km from Santa Ana
8.8 out of 10, Excellent, (6 reviews)
"Very dark room but only there to sleep so fine. "
United Kingdom
Paula
The price is CA $97
CA $106 total
includes taxes & fees
Oct 6 - Oct 7
Apartamentos Turísticos Insulae
A poolside view with a large pool, a covered seating area, and a multi-story building with balconies in the background.

15. Ona Mar Menor Golf & Spa

Ona Mar Menor Golf & Spa
5.0 star property
11.3 km from Santa Ana
8.6 out of 10, Excellent, (523 reviews)
"Had an excellent stay at this hotel with family,no complaints."
United Kingdom
Kevin
The price is CA $107
CA $118 total
includes taxes & fees
Oct 7 - Oct 8
Ona Mar Menor Golf & Spa
A modern living room with a sofa, a dining table, and a staircase.

16. Apartamentos Centro Histórico

Apartamentos Centro Histórico
3.0 star property
Casco Antiguo, 7.8 km from Santa Ana
7.8 out of 10, Good, (38 reviews)
"very clean, everything you needed in the kitchen,"
United Kingdom
Linda
The price is CA $92
CA $92 total
includes taxes & fees
Oct 6 - Oct 7
Apartamentos Centro Histórico
A bay window with a wooden table and two chairs, a potted plant, and a view of a hillside.

17. Apartamentos Turísticos Gran Vía

Apartamentos Turísticos Gran Vía
3.0 star property
Casco Antiguo, 7.6 km from Santa Ana
8.0 out of 10, Very good, (29 reviews)
"Spacious. Close to everything. "
Sweden
Veronica
The price is CA $102
CA $110 total
includes taxes & fees
Oct 7 - Oct 8
Apartamentos Turísticos Gran Vía
A modern living room with a sofa, two armchairs, a wooden coffee table, and a TV on a stand.

18. Puerta Real

Puerta Real
3.0 star property
Casco Antiguo, 7.6 km from Santa Ana
9.6 out of 10, Exceptional, (23 reviews)
"Clean, nice and nice staff "
United States
Mansour
The price is CA $122
CA $130 total
includes taxes & fees
Oct 18 - Oct 19
Puerta Real
A marina with numerous boats docked, surrounded by palm trees and a clear view of the sea.

19. Hotel Cristina

Hotel Cristina
3.0 star property
15.4 km from Santa Ana
9.4 out of 10, Exceptional, (195 reviews)
"Great hotel in a super location with very pleasant staff and an especially good breakfast. "
United Kingdom
Susan
The price is CA $96
CA $105 total
includes taxes & fees
Oct 11 - Oct 12
Hotel Cristina
A hotel room with a bed, a desk, a mirror, a window, and a painting of a bus.

20. Apartamentos Turísticos Distrito Romano

Apartamentos Turísticos Distrito Romano
3.0 star property
Casco Antiguo, 7.8 km from Santa Ana
9.0 out of 10, Wonderful, (2 reviews)
"La limpieza no era buena. Suciedad en nevera, baño, etc. Pero situación y acceso muy buenos. Cartagena una gran ciudad, con mucha historia que ver y conocer."
Spain
José A.
The price is CA $87
CA $95 total
includes taxes & fees
Oct 12 - Oct 13
Apartamentos Turísticos Distrito Romano
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
A coastal town with a lighthouse, rocky cliffs, and the ocean.
Photo by INDALOMANIA
Open Photo by INDALOMANIA

Diputación de Rincón de San Ginés

Unique features of Diputación de Rincón de San Ginés include the golf courses and spas. Make a stop by Calblanque, Monte de las Cenizas y Peña del Águila Regional Park or Islas Menores while you're exploring the area.
A coastal lighthouse on a rocky outcrop with a paved walkway nearby.
Photo by Валерий Дед
Open Photo by Валерий Дед

Cabo de Palos

Travelers like the historic sites in Cabo de Palos, and Lighthouse of Cabo de Palos is a top attraction you might want to visit.
An ancient amphitheater with a circular stage and tiered seating, surrounded by historic buildings and mountains in the background.

El Beal

El Beal is noteworthy for its restaurants, and you can make a stop at top attractions like Los Nietos Beach and El Vivero.
An ancient amphitheater surrounded by modern buildings and a port.
Photo by V & A
Open Photo by V & A

Cartagena Casco

Historic sites, museums, and waterfront views are some highlights of Cartagena Casco. Make a stop by Punic wall of Cartagena or Gran Hotel while you're exploring.
A sunset over a calm body of water with a silhouette of distant mountains.

La Azohia

You'll enjoy the monuments and historic sites in La Azohia. You might want to make time for a stop at Playa de San Ginés or Playa de La Chapineta.

Top Santa Ana Hotel Reviews

Hotel Lodomar Spa & Talasoterapia

Hotel Lodomar Spa & Talasoterapia

10/10 Excellent
"Perfect"
PEDRO FERNANDEZ 9-night trip
Posted 21 hours ago
Hotel Lodomar Spa & Talasoterapia

Frequently asked questions

When is the best time to go to Santa Ana?
The best time to visit Santa Ana, Murcia, Spain, is generally during the spring (April to June) and autumn (September to October) months.

During these periods, the weather is pleasantly warm, with average temperatures ranging from 20°C to 28°C, making it ideal for exploring the region's attractions without the intense heat of summer. You'll find fewer crowds compared to the peak summer season, allowing for a more relaxed experience at popular sites and beaches. This is great for couples looking for a romantic getaway or travellers who appreciate a quieter atmosphere.

The summer months of July and August can be very hot, often exceeding 35°C, which might be uncomfortable for sightseeing, though it's excellent for those who wish to spend their days by the coast. Winter, from November to March, is mild but can be a bit chilly for beach activities, with temperatures around 10°C to 15°C. However, it's a good time for those interested in cultural tours and local festivals without the summer crowds.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Santa Ana hotel for you.
How much is the nightly rate at a Santa Ana hotel?
Hotel prices in Santa Ana often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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