San Francisco Vacation Packages

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    Save up to CA $4,200 when you book a flight and hotel together*

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Your San Francisco Vacation

With plenty of highlights as well as hidden gems, this city is best experienced with a San Francisco vacation package. Check out places to stay in Downtown Guayaquil, which is good for views, culture and history. Make your trip to San Francisco even more exciting by including some sightseeing. Malecon 2000, Banco Pichincha Monumental Stadium and Mall del Sol Commercial Center are among the leading attractions worth exploring. A couple of clicks is all it takes to put together a customized San Francisco vacation on Expedia.

Top Holiday Package Deals in San Francisco

Price found within the past 48 hours. Click for updated prices.
Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE

Puerto Santa Ana
CA $1,150
per person
Oct 4 - Oct 11
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Guayaquil (GYE)
9.4/10 Exceptional! (109 reviews)
Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador

Tarqui
CA $3,071
per person
Oct 4 - Oct 11
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Guayaquil (GYE)
10/10 Exceptional! (3 reviews)
Hotel del Parque

Hotel del Parque

CA $2,533
per person
Oct 4 - Oct 11
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Guayaquil (GYE)
9.8/10 Exceptional! (133 reviews)
Oro Verde Manta

Oro Verde Manta

CA $1,938
per person
Oct 24 - Oct 31
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Guayaquil (GYE)
9.2/10 Wonderful! (770 reviews)
The breakfast was excellent and delicious, the staff were very friendly and you have access to “Mall del Pacífico” in front of the hotel

Reviewed on Sep 1, 2026

Hotel Ramada

Hotel Ramada

Downtown Guayaquil
CA $1,277
per person
Oct 4 - Oct 11
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Guayaquil (GYE)
8/10 Very good! (410 reviews)

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about San Francisco
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Find hotels in Ecuador
A statue of a soldier on a pedestal with a building in the background.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Central Market while you're in town.

Find hotels in Downtown Guayaquil
A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and Botanical Garden while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

Find hotels in Puerto Santa Ana
A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

1 out of top 10 points of interest in this area

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

Find hotels in Kennedy
A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.

Find hotels in Urdesa

San Francisco Hotel Deals

Oro Verde Guayaquil

Oro Verde Guayaquil

9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
CA $127
CA $144 total
Sep 18 - Sep 19
9.6/10 Exceptional! (1,001 reviews)
"Honestly recommend staff was very helpful understanding"

Reviewed on Sep 1, 2026

Oro Verde Guayaquil
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Fully refundable
CA $134
CA $151 total
Sep 26 - Sep 27
9.4/10 Exceptional! (1,006 reviews)
"N/a"

Reviewed on Sep 2, 2026

Holiday Inn Guayaquil Airport by IHG
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
CA $159
CA $179 total
Oct 4 - Oct 5
Wyndham Guayaquil Puerto Santa Ana
See all 449 properties in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a San Francisco vacation package cost?
From as little as CA $1,150. Yes, you read that right. Our San Francisco vacation packages are a simple way to make your dollars go much further. Bundle your hotels, flights and car rentals and discover this popular destination.
How do I get a cheap travel package to San Francisco?
Browse and lock in everything all in one place with our San Francisco vacation packages. We have deals on hotels, flights, tours and more that'll keep your wallet happy and your adventurous spirit busy. And, with more than 550 partner airlines and 1,000,000 properties globally to select from, you'll have endless opportunities to mix and match as you please.
How far in advance should I book my San Francisco vacation?
Search Expedia to compare airfares as soon as you know your travel dates. In many cases, you can purchase a ticket up to a year before departure. If you don't see your preferred carrier, or you have to book last minute, don't worry. The lowest prices to San Francisco occasionally appear within weeks of departure.
What does an Expedia San Francisco travel package include?
That depends on what sort of getaway you're contemplating. San Francisco travel deals can include flights, hotels and car rentals. You can mix and match to find the bundle that works for you! You can also add on experiences and activities after you've booked to get even bigger discounts.
What should I know before booking a San Francisco travel package?
So many places to travel to, so many things to see. With a package, you'll be able to cross more of them off your list. Combine your hotels, rental cars and flights and see how much you save.
Can I choose my airline with a San Francisco Expedia vacation package?
Yes, you can. We have more than 550 partner airlines worldwide, so fly with the carrier that best suits your travel preferences.
If I'm not able to travel, can I cancel my San Francisco vacation package?
Certainly, and we're here to help. You may be able to cancel and rebook your San Francisco vacation package at no cost if you booked in the last 24 hours. However, you may be charged a fee by your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans suddenly change, browse our Customer Service Portal for more information.

Things to do

Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

CA $169
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

CA $89
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Ecuador Paragliding Montañita

Ecuador Paragliding Montañita

CA $90
per adult
Ecuador Paragliding Montañita
See all activities in Guayaquil
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.