San Antonio Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
Photo by Sig
- Plan, book, travel with confidence
- Better togetherSave up to CA $1,096 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your San Antonio Vacation
Put together a custom vacation package to San Antonio and get ready to experience this incredible city how you like. Consider staying in the neighborhood of Llolleo, which is great for coastal beaches and much more. Fill your spare time with visits to Rocas de Santo Domingo Beach, Vina Casa Marin Winery and Rocas de Santo Domingo Golf Club, some of the things you should see during your trip to San Antonio. Don't delay exploring this city any longer. Your dream San Antonio vacation is a couple of clicks away with Expedia.
Top San Antonio Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Hotel Sommelier
Downtown Santiago
Price was CA $1,329, price is now CA $1,113 per person
CA $1,113
per person
Mar 24 - Mar 31
found 1 hour ago
Roundtrip non-stop flight included
Toronto (YTO) to Santiago (SCL)
8.8/10 Excellent! (231 reviews)
Excellent room that was clean, spaceous and with kitchen facilities
Reviewed on Jan 27, 2026
Hotel Andino
Providencia
Price was CA $1,014, price is now CA $889 per person
CA $889
per person
Apr 10 - Apr 16
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Santiago (SCL)
8/10 Very Good! (39 reviews)
Muy buena experiencia, lugar cómodo y super tranquilo.
Encantado volveré.
Reviewed on May 9, 2024
San Antonio Hotel Deals
Hotel Casino San Antonio by Enjoy
Dr. Nestor Fernandez Thomas No. 83 San Antonio
Fully refundableReserve now, pay when you stay
The price is CA $103 per night from Feb 24 to Feb 25
CA $103
CA $103 total
Feb 24 - Feb 25
7.8/10 Good! (320 reviews)
It was clean, conveniently located near cruise terminal roughly 15 minute walk, close to mall and great view of harbour and sunset
Reviewed on Jan 9, 2026
Hotel Puerto Mayor
Av 21 de Mayo 758 San Antonio
Fully refundableReserve now, pay when you stay
The price is CA $102 per night from Mar 2 to Mar 3
CA $102
CA $102 total
Mar 2 - Mar 3
Great Location for a pre–Ocean Cruise Stay
I had a very nice stay at the Puerto Mayor. It was a good value for the cost especially since it included breakfast. The hotel personnel were pleasant and the room was quiet. I stayed there before a cruise and the cab ride to the terminal only took a few minutes. That was a real convenience. The ...
Reviewed on Apr 17, 2023
Comfortable Suite in San Antonio - Modern and Practical
San Antonio Valparaíso
The price is CA $80 per night from Feb 9 to Feb 10
CA $80
CA $107 total
Feb 9 - Feb 10
10/10 Exceptional! (1 review)
The owners of these little cabins were so helpful! They even came and found us to pick us up as we were walking from the cruise ship port to their location! Yes it is walkable! After our stay they gave as a ride to the bus station as well! Not fancy but very comfortable. Would highly recommend! Wifi, ...
Reviewed on Dec 11, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in San Antonio
Isla Negra, Pablo Neruda's House, and San Alfonso del Mar
CA $139
per adult
Full Day Trip to Isla Negra, Pomaire & Undurraga Vineyard - Small Group
CA $243
per adult
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
