Penrose Vacation Packages

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Top Holiday Package Deals in Penrose

Price found within the past 48 hours. Click for updated prices.

Residence Inn by Marriott St Louis Downtown

Midtown

CA $1,365

per person

Nov 25 - Dec 2

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to St. Louis (STL)

7.8/10 Good! (1,002 reviews)

The Wildwood Hotel

CA $1,395

per person

Nov 25 - Dec 2

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to St. Louis (STL)

9.2/10 Wonderful! (1,657 reviews)

The Cheshire

CA $1,642

per person

Nov 25 - Dec 2

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to St. Louis (STL)

8.8/10 Excellent! (1,004 reviews)

Ameristar Casino Resort and Spa

CA $1,814

per person

Nov 25 - Dec 2

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to St. Louis (STL)

8.6/10 Excellent! (1,033 reviews)

Great, friendly staff. The rooms are clean and it is easy to park.

Reviewed on Sep 22, 2026

Moonrise Hotel

Delmar Loop

CA $1,672

per person

Nov 25 - Dec 2

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to St. Louis (STL)

9/10 Wonderful! (2,016 reviews)

I have stayed many times at the moonrise and have never had a bad experience. Easy free parking, walkable to concert venues, food, outdoor activities. Safe part of town and the rooftop bar is always fun to hang out in

Reviewed on Sep 23, 2026

Where to stay in Penrose

Find the best Penrose areas and neighborhoods for the activities you enjoy most. Learn more about Penrose

A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis

4 out of top 10 points of interest in this area

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch National Park or Kiener Plaza might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

A street with parked cars, a building with a sign reading "Brennan's", and a tree in front.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Penrose Hotel Deals

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO

Fully refundableReserve now, pay when you stay

CA $134

CA $156 total

Oct 4 - Oct 5

includes taxes & fees

8.8/10 Excellent! (3,416 reviews)

"There was no shampoo or conditioner and only 1 towel for 3 people. When I called to ask for some (from my room dripping wet because I was in the shower when I realized the shampoo and conditioner was empty, the lady working kept hanging up on me. The room was filthy and smelled. There was trash in ..."

Reviewed on Sep 23, 2026

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO

Fully refundableReserve now, pay when you stay

CA $188

CA $222 total

Oct 3 - Oct 4

includes taxes & fees

8.6/10 Excellent! (4,291 reviews)

"Room was clean and the amenities are great. Many options for food and drinks in the building and near by. Next door from the Gateway Arch. Great view."

Reviewed on Sep 23, 2026

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

Fully refundableReserve now, pay when you stay

CA $127

CA $149 total

Sep 28 - Sep 29

includes taxes & fees

9.2/10 Wonderful! (3,249 reviews)

"Staff was exceptional! Our room was clean, the free breakfast was pretty hearty including scrambled eggs, waffles, bagels, fruit, juices, coffee and more. Also enjoyed free on site parking!"

Reviewed on Sep 23, 2026

See all 2,000 properties in Penrose

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.