Title: Hotels by Independent in Northeast Missouri from CA $95 | Expedia.ca [Northeast Missouri Travel Guide](https://expedia.ca/Northeast-Missouri.dx6058818)[Hotels in Northeast Missouri](https://expedia.ca/Northeast-Missouri-Hotels.d6058818.Travel-Guide-Hotels)[Vacation Rentals in Northeast Missouri](https://expedia.ca/Northeast-Missouri-Vacation-Rentals.d6058818.Travel-Guide-VacationRentals)[Flights to Northeast Missouri](https://expedia.ca/Cheap-Flights-To-Northeast-Missouri.d6058818.Travel-Guide-Flights)[Things to do in Northeast Missouri](https://expedia.ca/Things-To-Do-In-Northeast-Missouri.d6058818.Travel-Guide-Activities)[Northeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Northeast-Missouri.d6058818.Car-Rental-Guide)[Northeast Missouri Vacation Packages](https://expedia.ca/Northeast-Missouri.d6058818.Destination-Travel-Guides) ![Grant\'s Farm which includes heritage architecture](https://images.trvl-media.com/place/6069377/88294c82-c384-49b1-b936-14bc595df677.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6069377/88294c82-c384-49b1-b936-14bc595df677.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 15 - Jan 16](https://www.expedia.ca/Hotel-Search?regionId=6058818&startDate=2026-01-15&endDate=2026-01-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 16 - Jan 17](https://www.expedia.ca/Hotel-Search?regionId=6058818&startDate=2026-01-16&endDate=2026-01-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6058818&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6058818&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Northeast Missouri Independent ![Standard Double Room](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/460db328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/1aedab62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/623aa763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels, soap](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/fa7a7814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Forest Park Hotel by MDR [](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-St-Louis-Forest-Park.h22298.Hotel-Information) The Hill 7.6/10 Good (1,311 reviews) "Staff was friendly and quick to assist when needed. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia [](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-St-Louis-Forest-Park.h22298.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/a7d1479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, a heated pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/5c61cbf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/13e26dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clayton Plaza Hotel & Extended Stay [](https://www.expedia.ca/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) Clayton 8.8/10 Excellent (3,069 reviews) "Great stay‼️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Calvin CA $131 CA $153 total includes taxes & fees Jan 24 - Jan 25 [](https://www.expedia.ca/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ![Gastropub](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/24983857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/c3a4349f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/b6ec06de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/3b7ec090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cheshire [](https://www.expedia.ca/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) Richmond Heights 8.6/10 Excellent (1,004 reviews) "The place is beautiful, the room is very cozy and comfortable, the hotel well located with good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria CA $179 CA $212 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) ![Cleanliness standards](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/49b4298c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/7aa0940e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/3d3bc786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/864a0b1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relax Inn Saint Charles [](https://www.expedia.ca/St-Louis-Hotels-Relax-Inn-Saint-Charles.h1000712.Hotel-Information) St. Charles 6.6/10 (1,002 reviews) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Askar CA $85 CA $98 total includes taxes & fees Jan 17 - Jan 18 [](https://www.expedia.ca/St-Louis-Hotels-Relax-Inn-Saint-Charles.h1000712.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/035dee6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | Jetted tub](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/801c113b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/9fbd251c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Wildwood Hotel [](https://www.expedia.ca/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) Wildwood 9.2/10 Wonderful (1,624 reviews) "Clean room, friendly staff and lots of activities in the immediate area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.ca/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1660000/1659000/1658956/a165f739.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1660000/1659000/1658956/ad47a940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/2000000/1660000/1659000/1658956/b4171890.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1660000/1659000/1658956/0d57c05f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West [](https://www.expedia.ca/St-Louis-Hotels-Larkspur-Landing-Extended-Stay-Suites-St-Louis-Riverport-Airport-West.h1658956.Hotel-Information) Maryland Heights 7.6/10 Good (1,001 reviews) "The room was clean and spacious and the staff was really nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) D CA $96 CA $112 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/St-Louis-Hotels-Larkspur-Landing-Extended-Stay-Suites-St-Louis-Riverport-Airport-West.h1658956.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/w2897h2195x0y8-cdf51e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/10a24838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/150f8d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/1004381f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moonrise Hotel [](https://www.expedia.ca/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) Delmar Loop 9.0/10 Wonderful (1,921 reviews) "Great staff | Fun decor | Fun area" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brett CA $173 CA $205 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/74ffd1da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/1f832e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/f77b5588.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining room](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/85647492.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The West End [](https://www.expedia.ca/St-Louis-Hotels-The-West-End.h106715696.Hotel-Information) Central West End 8.4/10 Very good (418 reviews) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shaniqua [](https://www.expedia.ca/St-Louis-Hotels-The-West-End.h106715696.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8597/eb625205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8597/eee6455d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8600/8597/3bf2ff2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/10000/8600/8597/5f015fac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Economy Inn Wentzville [](https://www.expedia.ca/St-Louis-Hotels-Economy-Inn-Wentzville.h8597.Hotel-Information) Wentzville 6.4/10 (513 reviews) "The room was dirty so dirty we left didn't spend the night there, and the smell in the building weed or something else not sure which, it was ridiculous so we went to Hannibal and stayed at the Days inn " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) paul CA $83 CA $95 total includes taxes & fees Jan 16 - Jan 17 [](https://www.expedia.ca/St-Louis-Hotels-Economy-Inn-Wentzville.h8597.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/a9bf89ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/cc76404d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/9c80d4ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/90b4f887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Knight Center at Washington University [](https://www.expedia.ca/St-Louis-Hotels-The-Charles-F-Knight-Center.h38711810.Hotel-Information) St. Louis 9.4/10 Exceptional (462 reviews) "Great place to stay, friendly staff, nice room, bathroom, and TV. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Natalie CA $235 CA $270 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/St-Louis-Hotels-The-Charles-F-Knight-Center.h38711810.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-29&endDate=2026-01-30®ionId=6058818&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FNortheast-Missouri-Hotels-Independent.0-0-d6058818--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FNortheast-Missouri-Hotels-Independent.0-0-d6058818--bIndependent.Travel-Guide-Filter-Hotels) ## Top Northeast Missouri Hotel Reviews ![Motel 6 Hazelwood, MO](https://images.trvl-media.com/lodging/1000000/10000/500/457/82f143a9_y.jpg) ### Motel 6 Hazelwood, MO 10/10 Excellent "Room clean, second time staying and all worked well. Staff was very helpful and welcomed." [](https://expedia.ca/St-Louis-Hotels-Motel-6-Hazelwood.h457.Hotel-Information) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cd6b7758_y.jpg) ### 21C Museum Hotel St Louis 10/10 Excellent "The hotel is beautiful! And most importantly, the bed was very comfortable. It has a fridge in the room, which most boutique hotels lack, so that was convenient. I would stay here again." [](https://expedia.ca/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ![Home2 Suites by Hilton St. Louis Downtown](https://images.trvl-media.com/lodging/77000000/76520000/76510800/76510729/104b5741_y.jpg) ### Home2 Suites by Hilton St. Louis Downtown 10/10 Excellent "The hotel and the room were very up-to-date, clean and inviting, the staff including the security guards (James, Norris and Mike) were all very professional, full of information about the area, restaurants and sights. They all went out of their way to help us and were so friendly. The breakfast was changing every day and better than your normal hotel breakfast. And the hotel was convenient to everything downtown" [](https://expedia.ca/St-Louis-Hotels-Home2-Suites-St-Louis-Downtown.h76510729.Hotel-Information) ![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd_y.jpg) ### Clayton Plaza Hotel & Extended Stay 10/10 Excellent "Overall great experience and amazing facility the pillows could use a upgrade but overall very happy." [](https://expedia.ca/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ![Angad Arts Hotel St. Louis, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8_y.jpg) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton 10/10 Excellent "I always love staying Angad art hotel!" [](https://expedia.ca/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) ![Renaissance St. Louis Airport Hotel](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/879431a1_y.jpg) ### Renaissance St. Louis Airport Hotel 10/10 Excellent "Our check in was flawless as always and the staff was very friendly" [](https://expedia.ca/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information) ![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/c42cf5fe_y.jpg) ### Ameristar Casino Resort and Spa 10/10 Excellent "Everything was beautiful from the hotel staff to the room. It was great." [](https://expedia.ca/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg) ### Pear Tree Inn St. Louis Airport 10/10 Excellent "Staff was first thing I noticed then clean room " [](https://expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 10/10 Excellent "Great except for the breakfast. Eggs were rubbery, bone in the sausage, orange was dry." 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