Name: Fairfield Inn & Suites by Marriott Sikeston
Price range: CA $152
Rating: 9.4

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Your New Madrid Vacation

Our vacation packages to New Madrid provide endless opportunities to delve into new sights, sounds and experiences. And with all the finer details taken care of, you can kick back and enjoy your city escape without a worry in the world. Make your trip to New Madrid even more fulfilling by going sightseeing. New Madrid Historical Museum, River Ridge Winery and Hunter-Dawson State Historic Site are among the top attractions you'll want to explore. Stop daydreaming and start traveling. Explore the wide range of options on Expedia today and put your New Madrid vacation plans in motion!

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New Madrid Hotel Deals

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

New Madrid MO

CA $277

CA $505 total

Jun 4 - Jun 5

includes taxes & fees

10/10 Exceptional! (1 review)

"The host was very quick to respond and so great to work with for on our stay."

Reviewed on Nov 11, 2025

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

Fully refundableReserve now, pay when you stay

CA $164

CA $186 total

Jun 14 - Jun 15

includes taxes & fees

9/10 Wonderful! (573 reviews)

"The doughnuts and fry potatoes for breakfast were delicious"

Reviewed on Jun 2, 2026

Fairfield Inn & Suites by Marriott Sikeston

1239 Commerce Drive Sikeston MO

Fully refundableReserve now, pay when you stay

CA $152

CA $172 total

Jun 21 - Jun 22

includes taxes & fees

9.4/10 Exceptional! (84 reviews)

"Great stay, kind staff, very clean property."

Reviewed on May 30, 2026

See all 58 properties in New Madrid

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.