Name: Hotel Anastassiou
Price range: CA $70

Your Mesopotamia Vacation

Our vacation packages to Mesopotamia let you create your own adventure. Tailor your getaway to your style and interests and make the most of your time in this wonderful city. Fill your schedule with tours of Kastoria Lake, Kastoria Aquarium and Holy Prophet Elias Church, some of the top attractions you really should see during a trip to Mesopotamia. Your ideal Mesopotamia vacation is a few clicks away. Search airfares, hotels and more on Expedia for an adventure that's tailored to suit your style.

Top Mesopotamia Vacation Deals

Price found within the past 48 hours. Click for updated prices.

Capsis Bristol Boutique Hotel

Thessaloniki City Centre

CA $914

per person

Aug 7 - Aug 13

found 1 day ago

Roundtrip flight included

Belgrade (BEG) to Thessaloniki (SKG)

9/10 Wonderful! (140 reviews)

Very nice room. Very freindly and helpful staff. Excellent breakfast and evening meal menu.

Reviewed on Jun 19, 2026

Wellness Santa Hotel - Adults Only

CA $1,366

per person

Aug 7 - Aug 13

found 1 day ago

Roundtrip flight included

Belgrade (BEG) to Thessaloniki (SKG)

8.4/10 Very good! (198 reviews)

liked this hotel in general

Reviewed on Jul 7, 2025

Sky Hotel

CA $1,326

per person

Aug 7 - Aug 13

found 1 day ago

Roundtrip flight included

Belgrade (BEG) to Thessaloniki (SKG)

9.4/10 Exceptional! (25 reviews)

It’s a nice boutique hotel with a good breakfast. It’s outside of the city. It’s close to an airport because there were flight crews that were staying there. It’s on the side closer to Phillipi if you’re interested in going there.

Reviewed on May 25, 2026

Bahar Boutique Hotel

Thessaloniki City Centre

CA $973

per person

Aug 7 - Aug 13

found 1 day ago

Roundtrip flight included

Belgrade (BEG) to Thessaloniki (SKG)

9.4/10 Exceptional! (89 reviews)

Great room very modern elegant decor, the staff goes above and beyond to help.AMAZING BREAKFAST WITH YOUR CHOISE FROM THE MENU COOKED TO ORDER AMAZING!!!

Reviewed on Feb 4, 2026

Sun Beach Hotel

CA $1,010

per person

Aug 7 - Aug 13

found 1 day ago

Roundtrip flight included

Belgrade (BEG) to Thessaloniki (SKG)

7.6/10 Good! (62 reviews)

No clear information on which rooms have single and separate beds.

Reviewed on May 28, 2026

Ready to book your vacation to Mesopotamia?

Choose your dates

Mesopotamia Hotel Deals

To Spiti tis Sofias

Mesopotamia Kastoria Western Macedonia

Fully refundableReserve now, pay when you stay

CA $92

CA $108 total

Jul 20 - Jul 21

includes taxes & fees

10/10 Exceptional! (1 review)

Le meilleur de notre séjour

"Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin."

Reviewed on Aug 18, 2025

Limneon Resort & Spa

4th km National Road Kastoria Athens Kastoria

Fully refundableReserve now, pay when you stay

CA $136

CA $179 total

Jul 20 - Jul 21

includes taxes & fees

9.2/10 Wonderful! (204 reviews)

"We had only a one night stay but it was lovely. Outdoor pool and breakfast were nice, bed is comfortable. The indoor pool and sauna area really need updating. But they are usable."

Reviewed on Jun 21, 2026

Hotel Anastassiou

1st km Highway Kastoria-Athens Kastoria Western Macedonia

Fully refundableReserve now, pay when you stay

CA $70

CA $83 total

Jul 3 - Jul 4

includes taxes & fees

See all 49 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.