Hannibal Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Hannibal Vacation

Excellent adventures await when you lock in a vacation package to Hannibal. Whether you're a history buff, foodie or just a traveler who loves to experience new places, there's something for everyone in this exciting city. Fill your spare time with tours of Mark Twain Boyhood Home and Museum, Mark Twain Cave and Cameron Cave and Mark Twain Cave, some of the attractions you shouldn't miss during your trip to Hannibal. Stop daydreaming and start traveling. Explore the broad range of options on Expedia today and put your Hannibal vacation plans into gear!

Top Hannibal Vacation Deals

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $1,316, price is now CA $924 per person
CA $924
per person
Aug 7 - Aug 10
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
9.2/10 Wonderful! (1,639 reviews)
Loved having a parking garage available. Having a dog area was great. Nice location with a movie theater right across the street. Hotel in a very safe area. Pressure on shower was excellent. Breakfast choices were very good. Refrigerator with a freezer was a tremendous amenity. Wonderful hotel except decor was tired. Also, the tranquilly of our room of three days was compromised by having the pool room directly below our room. Better design should have been done since hotel is charging full price for a room with a constant loud droning noise below it. Hotel should know this. Our family would stay here again BUT not in room 1119.

Reviewed on May 12, 2026

Hermann Grain Bins BNB

Hermann Grain Bins BNB

2 out of 5
Price was CA $2,535, price is now CA $1,989 per person
CA $1,989
per person
Jul 30 - Aug 4
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
2/10 (1 review)
The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
Central West End
Price was CA $1,235, price is now CA $1,033 per person
CA $1,033
per person
Aug 7 - Aug 10
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
9/10 Wonderful! (1,011 reviews)
Clean rooms, great staff

Reviewed on May 12, 2026

The Cheshire

The Cheshire

4 out of 5
Price was CA $1,164, price is now CA $985 per person
CA $985
per person
Aug 7 - Aug 10
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
8.8/10 Excellent! (1,006 reviews)
Fun, quirky hotel. Great free breakfast.

Reviewed on May 12, 2026

Osceola

Osceola

2 out of 5
Mount Pleasant
Price was CA $4,276, price is now CA $3,677 per person
CA $3,677
per person
Aug 7 - Aug 10
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
No reviews

Ready to book your vacation to Hannibal?

 

Choose your dates

Hannibal Hotel Deals

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
Fully refundable
The price is CA $117 per night from Jun 7 to Jun 8
CA $117
CA $137 total
Jun 7 - Jun 8
includes taxes & fees
8/10 Very Good! (1,015 reviews)
Not pleased with my stay. Booked on expedia-room with hot tub. Checked in, no room with hot tub, front desk said since i booked through 3rd party they did not get my reservation right with a hot tub. Nothing offered for thw inconvenience at first. I found the email with my reservation details which ...

Reviewed on May 12, 2026

Quality Inn & Suites Hannibal West
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
Fully refundableReserve now, pay when you stay
The price is CA $138 per night from May 17 to May 18
CA $138
CA $160 total
May 17 - May 18
includes taxes & fees
8.6/10 Excellent! (1,001 reviews)
Nice staff

Reviewed on May 12, 2026

Best Western On The River
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
Fully refundableReserve now, pay when you stay
The price is CA $77 per night from May 19 to May 20
CA $77
CA $88 total
May 19 - May 20
includes taxes & fees
7.4/10 Good! (1,000 reviews)
Parking was easy and secure. Check in was flawless. The room was clean and comfy

Reviewed on May 11, 2026

Motel 6 Hannibal, MO
See all 179 properties in Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Discover the most popular places to visit in Hannibal

Mark Twain Boyhood Home and Museum

Find out about the history of Hannibal when you take a trip to Mark Twain Boyhood Home and Museum. While in this walkable area, you can savor the top-notch restaurants.

Mark Twain Boyhood Home and Museum

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.