Hannibal Vacation Packages

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Your Hannibal Vacation

Excellent adventures await when you lock in a vacation package to Hannibal. Whether you're a history buff, foodie or just a traveler who loves to experience new places, there's something for everyone in this exciting city. Fill your spare time with tours of Mark Twain Boyhood Home and Museum, Mark Twain Cave and Cameron Cave and Mark Twain Cave, some of the attractions you shouldn't miss during your trip to Hannibal. Stop daydreaming and start traveling. Explore the broad range of options on Expedia today and put your Hannibal vacation plans into gear!

Top Hannibal Vacation Deals

Price found within the past 48 hours. Click for updated prices.
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
Price was CA $856, price is now CA $779 per person
CA $779
per person
Jun 15 - Jun 16
found 7 hours ago
Roundtrip flight included
Vancouver (YVR) to St. Louis (STL)
9/10 Wonderful! (1,539 reviews)
It was all great, clean, nice rooms, quiet and great staff!

Reviewed on May 13, 2026

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $917, price is now CA $799 per person
CA $799
per person
Jun 15 - Jun 16
found 7 hours ago
Roundtrip flight included
Vancouver (YVR) to St. Louis (STL)
9.2/10 Wonderful! (1,639 reviews)
Loved having a parking garage available. Having a dog area was great. Nice location with a movie theater right across the street. Hotel in a very safe area. Pressure on shower was excellent. Breakfast choices were very good. Refrigerator with a freezer was a tremendous amenity. Wonderful hotel except decor was tired. Also, the tranquilly of our room of three days was compromised by having the pool room directly below our room. Better design should have been done since hotel is charging full price for a room with a constant loud droning noise below it. Hotel should know this. Our family would stay here again BUT not in room 1119.

Reviewed on May 12, 2026

The Knight Center at Washington University

The Knight Center at Washington University

2.5 out of 5
Price was CA $929, price is now CA $854 per person
CA $854
per person
Jun 15 - Jun 16
found 7 hours ago
Roundtrip flight included
Vancouver (YVR) to St. Louis (STL)
9.4/10 Exceptional! (534 reviews)
Love the Knight center. Always clean, quiet and great place to stay if want to be close to WashU.

Reviewed on May 10, 2026

The Cheshire

The Cheshire

4 out of 5
Price was CA $915, price is now CA $847 per person
CA $847
per person
Jun 15 - Jun 16
found 7 hours ago
Roundtrip flight included
Vancouver (YVR) to St. Louis (STL)
8.8/10 Excellent! (1,006 reviews)
Fun, quirky hotel. Great free breakfast.

Reviewed on May 12, 2026

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
Downtown West
Price was CA $930, price is now CA $861 per person
CA $861
per person
Jun 15 - Jun 16
found 7 hours ago
Roundtrip flight included
Vancouver (YVR) to St. Louis (STL)
9/10 Wonderful! (1,819 reviews)
Great location, staff, and bar/restaurant. The art gallery is an incredible bonus, along with the workout facilities!

Reviewed on May 13, 2026

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Hannibal Hotel Deals

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
Fully refundable
The price is CA $113 per night from Jun 14 to Jun 15
CA $113
CA $131 total
Jun 14 - Jun 15
includes taxes & fees
8/10 Very Good! (1,019 reviews)
Clean rooms, nice jet tub in room. Staff was excellent

Reviewed on May 14, 2026

Quality Inn & Suites Hannibal West
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
Fully refundableReserve now, pay when you stay
The price is CA $138 per night from May 17 to May 18
CA $138
CA $160 total
May 17 - May 18
includes taxes & fees
8.6/10 Excellent! (1,002 reviews)
Rooms were very clean & well maintained. Parking was easy & safe. Very nice hotel.

Reviewed on May 13, 2026

Best Western On The River
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
Fully refundableReserve now, pay when you stay
The price is CA $77 per night from May 18 to May 19
CA $77
CA $88 total
May 18 - May 19
includes taxes & fees
7.4/10 Good! (1,000 reviews)
Parking was easy and secure. Check in was flawless. The room was clean and comfy

Reviewed on May 11, 2026

Motel 6 Hannibal, MO
See all 179 properties in Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Hannibal

Mark Twain Boyhood Home and Museum

Find out about the history of Hannibal when you take a trip to Mark Twain Boyhood Home and Museum. While in this walkable area, you can savor the top-notch restaurants.

Mark Twain Boyhood Home and Museum

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.