Hannibal Vacation Packages
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Your Hannibal Vacation
Excellent adventures await when you lock in a vacation package to Hannibal. Whether you're a history buff, foodie or just a traveler who loves to experience new places, there's something for everyone in this exciting city. Fill your spare time with tours of Mark Twain Boyhood Home and Museum, Mark Twain Cave and Cameron Cave and Mark Twain Cave, some of the attractions you shouldn't miss during your trip to Hannibal. Stop daydreaming and start traveling. Explore the broad range of options on Expedia today and put your Hannibal vacation plans into gear!
Top Hannibal Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Crowne Plaza St. Louis Airport by IHG
Price was CA $1,323, price is now CA $1,101 per person
CA $1,101
per person
Aug 20 - Aug 25
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
8/10 Very Good! (1,001 reviews)
Super loud inside and in the room. You can always hear the pool crowd. Also our room clearly had water damage in the bathroom and has just been patched up.
Reviewed on May 31, 2026
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Price was CA $1,371, price is now CA $1,140 per person
CA $1,140
per person
Jul 8 - Jul 12
found 1 day ago
Roundtrip flight included
Calgary (YYC) to St. Louis (STL)
8.8/10 Excellent! (1,003 reviews)
Stayed at this hotel for the weekend. Very nice hotel. Check in was easy. Stayed in king size bed room, with couch sofa. It was nice, didn’t use the sofa, but the room size was good for 2 ppl. Maybe it would be alittle crowded with more. Their beds are really comfortable. And showers have great pressure. The toilet acted up on our second day, but smone came out and took care of it right away.
The only con I’d give is for their buffet breakfast they offer 3 different kinds of bacon products. It would be nice to have smthing kosher. The only protein available were eggs and the rest sm type of pork protein. So the buffet breakfast was limited for us.
Other then that great hotel to stay in!
Reviewed on May 23, 2026
The Cheshire
Price was CA $1,565, price is now CA $1,311 per person
CA $1,311
per person
Aug 20 - Aug 25
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
8.8/10 Excellent! (1,000 reviews)
Kevin went above and beyond for my family when we were there for our daughter’s high school graduation! Made sure I always had a parking spot for my truck. Definitely recommend staying at the Cheshire. Definitely a different experience.
Reviewed on Jun 2, 2026
Hannibal Hotel Deals
Quality Inn & Suites Hannibal West
120 Lindsey Drive Hannibal MO
Fully refundable
The price is CA $111 per night from Jun 21 to Jun 22
CA $111
CA $129 total
Jun 21 - Jun 22
includes taxes & fees
8/10 Very Good! (1,002 reviews)
"Adequate place to stay. Clean and comfortable bed and room. Breakfast room needed attention(cups, food needed refilling, etc) but I would stay there again if I was looking for a place primarily to get a good night’s rest while traveling."
Reviewed on May 30, 2026
Best Western On The River
401 North 3rd Street Hannibal MO
Fully refundableReserve now, pay when you stay
The price is CA $164 per night from Jun 29 to Jun 30
CA $164
CA $189 total
Jun 29 - Jun 30
includes taxes & fees
8.6/10 Excellent! (1,000 reviews)
"Very strong chlorine smell from the inside courtyard pool. Felt damp"
Reviewed on Jun 2, 2026
Comfort Inn & Suites - Hannibal
4000 Market St Hannibal MO
Fully refundable
The price is CA $137 per night from Jun 14 to Jun 15
CA $137
CA $162 total
Jun 14 - Jun 15
includes taxes & fees
7.6/10 Good! (697 reviews)
"Ok"
Reviewed on Jun 3, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Hannibal
Mark Twain Boyhood Home and Museum
Find out about the history of Hannibal when you take a trip to Mark Twain Boyhood Home and Museum. While in this walkable area, you can savor the top-notch restaurants.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
