Hannibal Vacation Packages

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Your Hannibal Vacation

Excellent adventures await when you lock in a vacation package to Hannibal. Whether you're a history buff, foodie or just a traveler who loves to experience new places, there's something for everyone in this exciting city. Fill your spare time with tours of Mark Twain Boyhood Home and Museum, Mark Twain Cave and Cameron Cave and Mark Twain Cave, some of the attractions you shouldn't miss during your trip to Hannibal. Stop daydreaming and start traveling. Explore the broad range of options on Expedia today and put your Hannibal vacation plans into gear!

Top Hannibal Vacation Deals

Price found within the past 48 hours. Click for updated prices.
DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield

4 out of 5
Price was CA $773, price is now CA $645 per person
CA $645
per person
Apr 22 - Apr 25
found 18 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
8.6/10 Excellent! (1,001 reviews)
Room was clean and front counter staff was helpful

Reviewed on Feb 10, 2026

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $2,068, price is now CA $1,222 per person
CA $1,222
per person
Apr 22 - Apr 25
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Great staff. Safe place within walking distance of restaurants and activities. Clean room.

Reviewed on Feb 19, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
Grand Center
Price was CA $1,211, price is now CA $1,000 per person
CA $1,000
per person
Apr 22 - Apr 25
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
8.8/10 Excellent! (1,022 reviews)
Beautiful rooftop bar on this hotel! One block walking distance to the Fabulous Fox Theatre! Large comfortable rooms.

Reviewed on Feb 19, 2026

The Cheshire

The Cheshire

4 out of 5
Price was CA $1,102, price is now CA $920 per person
CA $920
per person
Mar 26 - Mar 29
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to St. Louis (STL)
8.6/10 Excellent! (1,002 reviews)
Room was great breakfast was great

Reviewed on Feb 14, 2026

The Knight Center at Washington University

The Knight Center at Washington University

2.5 out of 5
Price was CA $1,074, price is now CA $898 per person
CA $898
per person
Apr 22 - Apr 25
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
9.4/10 Exceptional! (425 reviews)
Very clean rooms. Clean and fresh feeling. Appreciated the bathrooms looking so nice and clean too! Will definitely stay there again. Only thing I’d change is I wish there were microwaves in the room.

Reviewed on Feb 16, 2026

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Hannibal Hotel Deals

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
Fully refundableReserve now, pay when you stay
The price is CA $95 per night from Mar 15 to Mar 16
CA $95
CA $111 total
Mar 15 - Mar 16
includes taxes & fees
8/10 Very Good! (1,010 reviews)
The room we had was VERY big. Plenty of space. We had a 2 queen room- probably could have easily fit 3-4 beds in there. Room was clean. Had good pillows not the cheap floppy kind. Bathroom was nothing to write home about but had really good water pressure. We went to the pool and it was ok- people ...

Reviewed on Feb 15, 2026

Quality Inn & Suites Hannibal West
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
Fully refundableReserve now, pay when you stay
The price is CA $96 per night from Feb 22 to Feb 23
CA $96
CA $111 total
Feb 22 - Feb 23
includes taxes & fees
8.6/10 Excellent! (1,003 reviews)
Interesting hotel but in a positive way

Reviewed on Feb 16, 2026

Best Western On The River
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
Fully refundable
The price is CA $147 per night from Mar 1 to Mar 2
CA $147
CA $170 total
Mar 1 - Mar 2
includes taxes & fees
9.6/10 Exceptional! (1,000 reviews)
Great stay

Reviewed on Feb 17, 2026

Sleep Inn & Suites Hannibal West
See all 173 properties in Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Hannibal

Mark Twain Boyhood Home and Museum

Find out about the history of Hannibal when you take a trip to Mark Twain Boyhood Home and Museum. While in this family-friendly area, you can savor the top-notch restaurants.

Mark Twain Boyhood Home and Museum

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.