Hannibal Vacation Packages

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Your Hannibal Vacation

Excellent adventures await when you lock in a vacation package to Hannibal. Whether you're a history buff, foodie or just a traveler who loves to experience new places, there's something for everyone in this exciting city. Fill your spare time with tours of Mark Twain Boyhood Home and Museum, Mark Twain Cave and Cameron Cave and Mark Twain Cave, some of the attractions you shouldn't miss during your trip to Hannibal. Stop daydreaming and start traveling. Explore the broad range of options on Expedia today and put your Hannibal vacation plans into gear!

Top Hannibal Vacation Deals

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $1,317, price is now CA $914 per person
CA $914
per person
Jul 24 - Jul 27
found 1 day ago
Roundtrip flight included
Toronto (YTO) to St. Louis (STL)
9.2/10 Wonderful! (1,627 reviews)
The entire stay was incredible

Reviewed on May 7, 2026

Hermann Grain Bins BNB

Hermann Grain Bins BNB

2 out of 5
Price was CA $3,118, price is now CA $2,428 per person
CA $2,428
per person
Jul 24 - Jul 31
found 12 hours ago
Roundtrip non-stop flight included
Montreal (YUL) to St. Louis (STL)
2/10 (1 review)
The Cheshire

The Cheshire

4 out of 5
Price was CA $1,334, price is now CA $1,082 per person
CA $1,082
per person
Jul 24 - Jul 27
found 1 day ago
Roundtrip flight included
Toronto (YTO) to St. Louis (STL)
8.6/10 Excellent! (1,007 reviews)
The overall upkeep and cleanliness is not great. The breakfast bar was ok but not as well stocked or organized as it used to be and the eggs were always cold. I stayed 4 nights.

Reviewed on May 10, 2026

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
Downtown West
Price was CA $1,612, price is now CA $1,330 per person
CA $1,330
per person
Jul 24 - Jul 27
found 1 day ago
Roundtrip flight included
Toronto (YTO) to St. Louis (STL)
9/10 Wonderful! (1,797 reviews)
Loved the look of the building and where it was located but the one thing I didn't like was there was no stairs. Everyone had to use the elevator.

Reviewed on May 9, 2026

Osceola

Osceola

2 out of 5
Mount Pleasant
Price was CA $5,600, price is now CA $4,639 per person
CA $4,639
per person
Jul 24 - Jul 27
found 1 day ago
Roundtrip flight included
Toronto (YTO) to St. Louis (STL)
No reviews

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Hannibal Hotel Deals

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
Fully refundable
The price is CA $108 per night from Jun 7 to Jun 8
CA $108
CA $126 total
Jun 7 - Jun 8
includes taxes & fees
8/10 Very Good! (1,012 reviews)
Very nice hot breakfast! Quiet room, pleasant experience. The restaurant next door, Fiddlers, has excellent food too!

Reviewed on May 9, 2026

Quality Inn & Suites Hannibal West
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
Fully refundableReserve now, pay when you stay
The price is CA $150 per night from May 12 to May 13
CA $150
CA $174 total
May 12 - May 13
includes taxes & fees
8.6/10 Excellent! (1,011 reviews)
Beautiful older property, so well kept! The indoor pool is an amazing relic, made the hall very humid, but no issues in the room. Parking was soooo convenient. Location was so close to all of the riverfront attractions and restaurants. Staff was so friendly and helpful. Great breakfast! So many ...

Reviewed on May 9, 2026

Best Western On The River
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St Hannibal MO
Fully refundable
The price is CA $123 per night from May 31 to Jun 1
CA $123
CA $146 total
May 31 - Jun 1
includes taxes & fees
7.6/10 Good! (690 reviews)
Very clean hotel, nothing fancy but everything was very nice. Would recommend.

Reviewed on Apr 28, 2026

Comfort Inn & Suites - Hannibal
See all 179 properties in Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Hannibal

Mark Twain Boyhood Home and Museum

Find out about the history of Hannibal when you take a trip to Mark Twain Boyhood Home and Museum. While in this walkable area, you can savor the top-notch restaurants.

Mark Twain Boyhood Home and Museum

What to do in Hannibal

Hannibal MO

Mark Twains Hannibal Smartphone Walking Tour Plays as you walk

CA $10
per adult
Mark Twains Hannibal Smartphone Walking Tour Plays as you walk
See all activities in Hannibal

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