10 Best Hotels in Grand Isle, Port St. Joe for 2026

Grand Isle
Port St. Joe
Florida
United States of America
Hotels
Expedia.ca

Vacation Rentals in Port St. Joe Flights to Port St. Joe Things to do in Port St. Joe Grand Isle Car Rentals Grand Isle Vacations

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Our top choices for Grand Isle hotels

A wooden boardwalk leading to a beach with clear skies.

A room with a sliding glass door leading to a balcony with a view of the beach.

A hotel room with a bed, a desk, a chair, a refrigerator, and a sliding door to the balcony.

A beachfront hotel with multiple floors, a red roof, and a staircase leading to the beach.

1. Driftwood Inn

Driftwood Inn

2.0 star property

0.5 km from Grand Isle

9.6 out of 10, Exceptional, (137 reviews)

9.6/10

Exceptional

(137 reviews)

"Right on the beach"

Jeff

The price is CA $217

CA $217

CA $243 total

includes taxes & fees

Dec 1 - Dec 2

Driftwood Inn

A black double door entrance with a black mat, white walls, and two large green planters with flowers.

A modern interior with a staircase, a sofa, a coffee table, and potted plants.

A covered outdoor area with a white ceiling, a ceiling fan, a wooden table, and two lounge chairs.

A sign for Port Inn with the number 501, surrounded by greenery and a building in the background.

2. The Port Inn - Port St Joe, an Ascend Collection Hotel

The Port Inn - Port St Joe, an Ascend Collection Hotel

3.5 star property

Downtown Port St. Joe, 17.9 km from Grand Isle

9.0 out of 10, Wonderful, (483 reviews)

9.0/10

Wonderful

(483 reviews)

"The property is adorable and the staff was amazing. I really could not ask for a better experience."

Elizabeth

The price is CA $186

CA $186

CA $208 total

includes taxes & fees

Nov 30 - Dec 1

The Port Inn - Port St Joe, an Ascend Collection Hotel

A building facade with large windows, a wooden planter with greenery, and a sign with the number '8010'.

A hotel corridor with numbered doors, wicker chairs, and a doormat with text.

A hotel room with two beds, a mural of a surfer on a wave, and a poster of Port St. Joe, Florida.

3. The Blu - A Boutique Motel

The Blu - A Boutique Motel

5.5 km from Grand Isle

10.0 out of 10, Exceptional, (3 reviews)

10/10

Exceptional

(3 reviews)

"Location was great"

Christy

The price is CA $223

CA $223

CA $328 total

includes taxes & fees

Nov 15 - Nov 16

The Blu - A Boutique Motel

A breakfast bar with seating, a refrigerator stocked with food, and a sign indicating breakfast service.

A hotel lobby with a reception desk, seating area, and a view through the glass doors.

A compact kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, a dishwasher, and a coffee maker.

A compact living space with a green sofa, a wooden table, a TV on a wooden cabinet, and a kitchenette in the background.

4. MainStay Suites Port Saint Joe South

MainStay Suites Port Saint Joe South

2.5 star property

22.1 km from Grand Isle

8.6 out of 10, Excellent, (794 reviews)

8.6/10

Excellent

(794 reviews)

"Great location to many attractions great staff and room"

Darryl

The price is CA $149

CA $149

CA $167 total

includes taxes & fees

Dec 13 - Dec 14

MainStay Suites Port Saint Joe South

A hotel room with a large bathtub, a sofa, a small table, a bed, and a large mirror.

A spacious lobby with a modern design, featuring a blue sofa, red armchair, and a decorative wall with abstract art.

An indoor swimming pool with red beams, large windows, and sunlit areas with lounge chairs.

A spacious hotel dining area with multiple tables and chairs, a kitchen in the background, and artwork on the walls.

5. Comfort Suites

Comfort Suites

2.5 star property

29 km from Grand Isle

8.4 out of 10, Very good, (833 reviews)

8.4/10

Very good

(833 reviews)

"place was clean and safe. Bed was good and breakfast was hot."

Sandra

The price is CA $107

CA $107

CA $116 total

includes taxes & fees

Dec 6 - Dec 7

Comfort Suites

A Holiday Inn Express & Suites hotel with a covered entrance, palm trees, and a parking lot.

A buffet with various food items, including omelets and other dishes, served in metal containers.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view of greenery.

A reception desk with a modern design, featuring a blue accent panel and a wall-mounted sign that reads "Holiday Inn Express & Suites".

6. Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

2.5 star property

29.1 km from Grand Isle

8.6 out of 10, Excellent, (539 reviews)

8.6/10

Excellent

(539 reviews)

"Great for the price."

Anita

The price is CA $129

CA $129

CA $140 total

includes taxes & fees

Dec 13 - Dec 14

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

A hotel sign for Candlewood Suites, an IHG hotel, with a parking lot and cars in front.

A modern building with a covered outdoor seating area, a fire pit, and a barbecue grill.

A modern living room with a sofa, coffee table, and a TV. There is a kitchen area with cabinets and a microwave.

A modern interior with a Candlewood Cupboard, a refrigerated beverage display, and seating area with a view.

7. Candlewood Suites Panama City Tyndall AFB by IHG

Candlewood Suites Panama City Tyndall AFB by IHG

2.5 star property

28.6 km from Grand Isle

9.4 out of 10, Exceptional, (109 reviews)

9.4/10

Exceptional

(109 reviews)

"Clean hotel."

Patricia

The price is CA $160

CA $160

CA $173 total

includes taxes & fees

Nov 14 - Nov 15

Candlewood Suites Panama City Tyndall AFB by IHG

A hotel room with two beds, a nightstand with a lamp, and a beach mural on the wall.

A reception area with two grey armchairs, a reception desk, potted plants, and artwork on the walls.

A modern kitchen with a dining area, equipped with a coffee machine, microwave, and a flat-screen TV.

A swimming pool with lounge chairs and a building in the background.

8. Days Inn by Wyndham Panama City/Callaway

Days Inn by Wyndham Panama City/Callaway

2.0 star property

29.4 km from Grand Isle

6.8 out of 10, (576 reviews)

6.8/10

(576 reviews)

"We found trash in our room. Behind night stand and behind the beds. The pool outside looked horrible."

Marion

The price is CA $79

CA $79

CA $85 total

includes taxes & fees

Dec 6 - Dec 7

Days Inn by Wyndham Panama City/Callaway

A hotel room with two beds, wooden flooring, and a window with blinds.

A laundry facility with multiple washing machines and dryers, each with a control panel and payment card reader.

A reception area with a wooden counter, a hand sanitizer dispenser, and a sign indicating the office.

A multi-story hotel with a central entrance, parking lot, and a clear sky.

9. Extended Stay America Select Suites - Panama City - Callaway

Extended Stay America Select Suites - Panama City - Callaway

2.5 star property

30.1 km from Grand Isle

6.2 out of 10, (550 reviews)

6.2/10

(550 reviews)

"Clean"

Yeriel

The price is CA $91

CA $91

CA $98 total

includes taxes & fees

Dec 7 - Dec 8

Extended Stay America Select Suites - Panama City - Callaway

A wooden staircase leading to a beach with waves and a sunset in the background.

An outdoor patio with chairs and tables, overlooking a lake and surrounded by trees.

A view of a lake with a dock, a small shed, and a house with a red roof.

A two-story building with a balcony, a deck, and a sandy beach in the background.

10. Cape San Blas Inn

Cape San Blas Inn

3.0 star property

27 km from Grand Isle

9.8 out of 10, Exceptional, (82 reviews)

9.8/10

Exceptional

(82 reviews)

"I loved the back deck with a hot tub to look at the stars, as well as paddleboards, kayaks, and bicycles for use."

Brittany

The price is CA $426

CA $426

CA $477 total

includes taxes & fees

Nov 15 - Nov 16

Cape San Blas Inn

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Where to stay in Grand Isle

Find the best Grand Isle areas and neighborhoods for the activities you enjoy most.

Downtown Port St. Joe
Cape Breezes
Gulf Aire
Waterside Village
Palms

A marina at sunset with boats docked and a wooden pier.

An aerial view of a town with a mix of commercial and residential buildings, a large parking lot, and a body of water.

A beach at sunset with a calm sea, a small water body, and distant buildings.

A lighthouse and a white house with a porch at dusk.

View properties in map for Downtown Port St. Joe

Downtown Port St. Joe

While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Constitution Convention Museum State Park.

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A white house with a black roof, a white lighthouse with a black top, and a calm lake with purple flowers in the foreground.

View properties in map for Cape Breezes

Cape Breezes

While Cape Breezes isn't home to many top sights, T.H. Stone Memorial St. Joseph Peninsula State Park and St. Joseph Peninsula State Park are some notable places to visit nearby.

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A beach with driftwood formations at sunset.

View properties in map for Gulf Aire

Gulf Aire

While Gulf Aire isn't home to many top sights, Saint Joe Beach and Mexico Beach are some notable places to visit nearby.

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A sandy beach with calm waters and a large cloud in the sky.

View properties in map for Waterside Village

Waterside Village

Though Waterside Village might not have many top sights, you can venture to the surrounding area to see attractions like Mexico Beach Marina and Mexico Beach.

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A coastal landscape with tall grasses, a palm tree, and a sunset over the water.

View properties in map for Palms

Palms

While there might not be top attractions in Palms, you can explore the larger area and discover places like Mexico Beach and Mexico Beach Marina.

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Top Grand Isle Hotel Reviews

Coastal 3 BR Townhome overlooking St Joe Bay/Golf Cart/Pools/Steps to Beach

10/10 Excellent

"Very new and clean unit. The golf cart was a nice touch even though we elected to not use it. Just across the road from the beach but you can take the golf cart or drive and park by the road. It's just a few minutes drive to get to Windmark proper or Port St Joe. The host was very timely with communications and responding to questions which is always important if you're traveling from out of town."

William E. 7-night trip

Posted 8 hours ago

Coastal 3 BR Townhome overlooking St Joe Bay/Golf Cart/Pools/Steps to Beach

Driftwood Inn

10/10 Excellent

"Right on the beach"

Jeff 4-night trip

Posted 5 days ago

Driftwood Inn

New Wide Beach! Gulf-Front Fall & Winter Escape - 2 Kings - Dog-Friendly

8/10 Good

"Great house in a wonderful location! The beach view could not have been better. The screened-in porch was excellent for dining, relaxing and enjoying the view."

Stephanie L. 3-night trip

Posted 2 weeks ago

New Wide Beach! Gulf-Front Fall & Winter Escape - 2 Kings - Dog-Friendly

⛳️New Heated Pool, Putting green & steps away from Private Beach Access⛳️

10/10 Excellent

"We absolutely loved our stay at this beautiful home! From the gorgeous sunrise and sunset views to the incredible views of the ocean and beach, everything about this property was wonderful. The home is brand new, beautifully designed, exceptionally clean, and so comfortable. There was plenty of space for our family to spread out, relax, and truly enjoy our vacation.The attention to detail really sets this home apart! Every little thing has been thought of, from the fully stocked kitchen with a great spice rack and everything you could possibly need to cook meals throughout the week, to fun extras like a Mahjong set and even a Mahjong pool mat! It’s those thoughtful touches that make a vacation home feel extra special.The location on the North Cape is fantastic! It’s a quiet, peaceful stretch of beach, and the easy, straight walk to the beach with no stairs was such a bonus.What truly makes this property exceptional, though, is the host! She personally manages the home and goes above and beyond to be kind, helpful, and accommodating. You can genuinely tell how much she cares about her guests and their experience.We’ve stayed in many vacation homes over the years, and this one truly stands out. It was exactly the relaxing family getaway we needed, and we were so sad to leave! We would absolutely stay here again and can’t recommend it enough!"

Meagan F. 5-night trip

Posted 3 weeks ago

⛳️New Heated Pool, Putting green & steps away from Private Beach Access⛳️

Comfy family friendly house, short stroll to the beach!

10/10 Excellent

"This is a great house, and the host is amazing. We had a delay at the start due to Hurricane Isaias, and we contacted the host to extend at the end. We offered to pay for the extra day and were told "stay at no cost". Not typical host behavior. The house is in a neighborhood with the beach, pools, playgrounds, and other amenities within easy walking distance.The area is easily one of the best "beach" experiences we've ever had. Low traffic, lots of great restaurants, amazing beaches (definitely recommend the State Park), and a "chill" vibe. Absolutely no fighting for a place to set up on the beach. Every place we went, we were met with friendly people. I strongly recommend this home, this host, and this slice of Gulf heaven."

Stephen D. 8-night trip

Posted 3 weeks ago

Comfy family friendly house, short stroll to the beach!

NEW The Funky Oyster A4 w/Pool access Port St Joe

10/10 Excellent

"The house was very clean and spacious. The first night was a little rough but it was mostly due to the group we went with. They left after the second night and went to PC because there 4 teenagers were bored. Our kids are grown. My husband and I stayed and enjoyed the beach and the pool. I will say that the pool is a little walk from the house. If you plan on grilling just no they have community grills set up in different areas. All in all for the money it is a great place to visit. It not for people with kids that like to shop or just want to walk on the beach from where they are staying. Port St Joe is more for people who want to get away and take it easy."

Angela D. 3-night trip

Posted 5 months ago

NEW The Funky Oyster A4 w/Pool access Port St Joe

Frequently asked questions

What is Grand Isle like?

Travelers to Mexico Beach's Grand Isle neighborhood will be sure to enjoy a stay in this neighborhood.

How many hotels will I find in Grand Isle?

When you want to kick up your feet after a day of exploring the sights in Mexico Beach, you can choose from 11 Expedia hotels and other accommodations in Grand Isle.

If I need to cancel my hotel reservation in Grand Isle, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best options available in Grand Isle.

What is there to do around this Mexico Beach neighborhood?

Mexico Beach Business Center, Mexico Beach, and Mexico Beach Marina are just a few of the places to visit in and around Grand Isle. When you're sightseeing around the area, Saint Joe Beach and Windmark Beach are a couple of other sights to visit.

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Hotels in Grand Isle, Port St. Joe

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Grand Isle hotels

1. Driftwood Inn

2. The Port Inn - Port St Joe, an Ascend Collection Hotel

3. The Blu - A Boutique Motel

4. MainStay Suites Port Saint Joe South

5. Comfort Suites

6. Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

7. Candlewood Suites Panama City Tyndall AFB by IHG

8. Days Inn by Wyndham Panama City/Callaway

9. Extended Stay America Select Suites - Panama City - Callaway

10. Cape San Blas Inn

Where to stay in Grand Isle

Downtown Port St. Joe

Cape Breezes

Gulf Aire

Waterside Village

Palms

Top Grand Isle Hotel Reviews

Coastal 3 BR Townhome overlooking St Joe Bay/Golf Cart/Pools/Steps to Beach

Frequently asked questions

Explore a world of travel with Expedia