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Where to stay in East Main Street

Find the best East Main Street areas and neighborhoods for the activities you enjoy most. Learn more about East Main Street

A winding road with a yellow warning sign, surrounded by rocky cliffs and sparse vegetation.

Redlands

1 out of top 10 points of interest in this area

You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.

An aerial view of a city at night with illuminated streets and buildings.

Downtown

1 out of top 10 points of interest in this area

While there might not be top attractions in Downtown, you can explore the larger area and discover places like Museum of the West and Western Colorado Botanical Gardens.

A lone tree in a rocky landscape with mountains in the background.

Pear Park

If you're spending some time in Pear Park, Colorado River and James M. Robb – Colorado River State Park are top sights worth seeing.

A canyon landscape with prominent red rock formations and a distant mountain range.

Historic Grand Junction

Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

A canyon landscape with prominent rock formations, a distant city, and snow-capped mountains in the background.

Horizon Drive District

While there might not be top attractions in Horizon Drive District, you can explore the larger area and discover places like Grand Junction Motor Speedway and Canyon View Park.

East Main Street Hotel Deals

It's all about Location! This Downtown Retreat = easy access to the heart of GJ.

Grand Junction CO

10/10 Exceptional! (45 reviews)

"This property worked out great for us. We were in town for a baseball tournament. The location was great for getting to the fields and exploring downtown. The home was very clean and check in was very convenient. Response time from the host was fast. We would absolutely stay here again."

Reviewed on Sep 7, 2026

Get rates

Grand Vista Hotel

2790 Crossroads Blvd Grand Junction CO

Fully refundableReserve now, pay when you stay

CA $103

CA $118 total

Oct 7 - Oct 8

includes taxes & fees

8.2/10 Very good! (3,966 reviews)

"Great place to stay! We needed a place on very short notice and this was a perfect spot for us! :)"

Reviewed on Sep 13, 2026

Super 8 by Wyndham Grand Junction Colorado

728 Horizon Drive Grand Junction CO

Fully refundableReserve now, pay when you stay

CA $85

CA $97 total

Sep 20 - Sep 21

includes taxes & fees

7.4/10 Good! (1,004 reviews)

"The hotel was an affordable spot to stay, however, we felt like we should’ve gone somewhere else. The smoking rooms invaded on our non-smoking room. The hallways were very dirty with torn carpets. The rooms were getting dated and very used with rusting fixtures and items like a broken toilet seat ..."

Reviewed on Sep 13, 2026

See all 552 properties in East Main Street

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.