Title: The 10 Best Hotels Near Don and Sybil Harrington Cancer Center, Amarillo from CA $99 | Expedia.ca [Vacation Rentals in Amarillo](https://expedia.ca/Amarillo-Vacation-Rentals.d371.Travel-Guide-VacationRentals)[Flights to Amarillo](https://expedia.ca/Cheap-Flights-To-Amarillo.d371.Travel-Guide-Flights)[Things to do in Amarillo](https://expedia.ca/Things-To-Do-In-Amarillo.d371.Travel-Guide-Activities)[Don and Sybil Harrington Cancer Center Car Rentals](https://expedia.ca/Car-Rentals-In-Don-And-Sybil-Harrington-Cancer-Center.d6080861.Car-Rental-Guide)[Don and Sybil Harrington Cancer Center Vacations](https://expedia.ca/Don-And-Sybil-Harrington-Cancer-Center-Amarillo.d6080861.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 14 - Jan 15](https://www.expedia.ca/Hotel-Search?regionId=6080861&startDate=2026-01-14&endDate=2026-01-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 15 - Jan 16](https://www.expedia.ca/Hotel-Search?regionId=6080861&startDate=2026-01-15&endDate=2026-01-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6080861&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6080861&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Don and Sybil Harrington Cancer Center hotels ![Lobby](https://images.trvl-media.com/lodging/33000000/32460000/32451100/32451099/8215c55d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/33000000/32460000/32451100/32451099/e3bc6adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/33000000/32460000/32451100/32451099/7e7c4172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/33000000/32460000/32451100/32451099/b596b979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Medical Center [](https://www.expedia.ca/Amarillo-Hotels-Best-Western-Plus-Medical-Center.h32451099.Hotel-Information) 0.4 km from Don and Sybil Harrington Cancer Center 9.4/10 Exceptional (2,080 reviews) "It was such a joyful night, spending with my family at this hotel, our kids loved the indoor pool. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mukhtar CA $136 CA $157 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Amarillo-Hotels-Best-Western-Plus-Medical-Center.h32451099.Hotel-Information) ![37-inch LCD TV with cable channels, TV, iPod dock](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/afe1eae2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/5b0048f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/405c342e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/1946cd63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Amarillo West by IHG [](https://www.expedia.ca/Amarillo-Hotels-Holiday-Inn-Express-Hotel-Suites-Amarillo-West.h4270804.Hotel-Information) 1.4 km from Don and Sybil Harrington Cancer Center 9.4/10 Exceptional (2,054 reviews) "Great room and the breakfast selection was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan CA $144 CA $166 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Amarillo-Hotels-Holiday-Inn-Express-Hotel-Suites-Amarillo-West.h4270804.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/44000000/43540000/43532000/43531916/da467da8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/44000000/43540000/43532000/43531916/2dbae7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/44000000/43540000/43532000/43531916/7bc26d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/44000000/43540000/43532000/43531916/40192630.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Amarillo West/Medical Center [](https://www.expedia.ca/Amarillo-Hotels-TownePlace-Suites-By-Marriott-Amarillo-WestMedical-Center.h43531916.Hotel-Information) 1.2 km from Don and Sybil Harrington Cancer Center 9.4/10 Exceptional (490 reviews) "Clean rooms and very nice staff. Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) david CA $157 CA $180 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Amarillo-Hotels-TownePlace-Suites-By-Marriott-Amarillo-WestMedical-Center.h43531916.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/104000000/103990000/103987500/103987448/600c238c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/104000000/103990000/103987500/103987448/680dceed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/104000000/103990000/103987500/103987448/8895471c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/104000000/103990000/103987500/103987448/dfc3d2f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Amarillo West [](https://www.expedia.ca/Amarillo-Hotels-Hampton-Inn-Suites-Amarillo-West.h103987448.Hotel-Information) 1.7 km from Don and Sybil Harrington Cancer Center 9.4/10 Exceptional (417 reviews) "Beautiful hotel! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nohemy CA $135 CA $156 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Amarillo-Hotels-Hampton-Inn-Suites-Amarillo-West.h103987448.Hotel-Information) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/14000000/13470000/13461200/13461144/w3000h1897x0y3-89fe6407.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13470000/13461200/13461144/w3000h1897x0y3-9d0d630b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/14000000/13470000/13461200/13461144/ea27617b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/14000000/13470000/13461200/13461144/9c968532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### My Place Hotel - Amarillo West/ Medical Center, TX [](https://www.expedia.ca/Amarillo-Hotels-My-Place-Hotel-Amarillo-West-Medical-Center.h13461144.Hotel-Information) 1.6 km from Don and Sybil Harrington Cancer Center 9.2/10 Wonderful (1,337 reviews) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) juan f. CA $105 CA $121 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Amarillo-Hotels-My-Place-Hotel-Amarillo-West-Medical-Center.h13461144.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/728bf030.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/5e093502.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/98b35323.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/887f87c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Amarillo [](https://www.expedia.ca/Amarillo-Hotels-Drury-Inn-Suites-Amarillo.h1529725.Hotel-Information) 1.9 km from Don and Sybil Harrington Cancer Center 9.4/10 Exceptional (2,215 reviews) "The room was very clean, the breakfast was delicious and the staff was super friendly! We’ll definitely be staying there again on our next trip. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda CA $121 CA $139 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Amarillo-Hotels-Drury-Inn-Suites-Amarillo.h1529725.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/123000000/122840000/122839400/122839385/b27a5383.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/123000000/122840000/122839400/122839385/469c407d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/123000000/122840000/122839400/122839385/1d2658a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible Bathtub](https://images.trvl-media.com/lodging/123000000/122840000/122839400/122839385/fc4a3765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yellow City Studios [](https://www.expedia.ca/Amarillo-Hotels-Yellow-City-Studios.h122839385.Hotel-Information) 1 km from Don and Sybil Harrington Cancer Center 9.0/10 Wonderful (64 reviews) "Probably the cleanest to stay in Amarillo. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tommie CA $107 CA $124 total includes taxes & fees Jan 15 - Jan 16 [](https://www.expedia.ca/Amarillo-Hotels-Yellow-City-Studios.h122839385.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/28000000/27240000/27238100/27238096/7988a930.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27240000/27238100/27238096/bfe766f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/28000000/27240000/27238100/27238096/1ea94e47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27240000/27238100/27238096/9a7e38c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Amarillo West [](https://www.expedia.ca/Amarillo-Hotels-Tru-By-Hilton-Amarillo-West.h27238096.Hotel-Information) 2.1 km from Don and Sybil Harrington Cancer Center 9.2/10 Wonderful (1,140 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annetta CA $107 CA $124 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Amarillo-Hotels-Tru-By-Hilton-Amarillo-West.h27238096.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/17000000/16410000/16403000/16402985/b0ed43c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/17000000/16410000/16403000/16402985/abf9ebaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/17000000/16410000/16403000/16402985/aa11459f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/17000000/16410000/16403000/16402985/8e9257a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Springhill Suites by Marriott Amarillo [](https://www.expedia.ca/Amarillo-Hotels-Springhill-Suites-By-Marriott-Amarillo.h16402985.Hotel-Information) 1.6 km from Don and Sybil Harrington Cancer Center 9.2/10 Wonderful (1,000 reviews) "Staff was very friendly and went above and beyond to make our stay a great one. Large rooms and well maintained." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $146 CA $168 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Amarillo-Hotels-Springhill-Suites-By-Marriott-Amarillo.h16402985.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/9ed9fb8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/16855c6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 6:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/f8cb3c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/1081cf4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Amarillo-West [](https://www.expedia.ca/Amarillo-Hotels-Hyatt-Place-Amarillo-West.h44370546.Hotel-Information) 2.2 km from Don and Sybil Harrington Cancer Center 9.2/10 Wonderful (1,377 reviews) "Really nice place and very clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Claudia CA $117 CA $136 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Amarillo-Hotels-Hyatt-Place-Amarillo-West.h44370546.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9740000/9733400/9733400/5203d67e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/10000000/9740000/9733400/9733400/43f00102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9740000/9733400/9733400/9db02856.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9740000/9733400/9733400/e9431a32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Amarillo [](https://www.expedia.ca/Amarillo-Hotels-Home2-Suites-By-Hilton-Amarillo.h9733400.Hotel-Information) 1.3 km from Don and Sybil Harrington Cancer Center 9.0/10 Wonderful (1,016 reviews) "We had a great stay. Room was clean and spacious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lacey CA $117 CA $134 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Amarillo-Hotels-Home2-Suites-By-Hilton-Amarillo.h9733400.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/0abb04c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/cdb90461.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/96870b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/4a9a0279.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Amarillo I-40 West, TX [](https://www.expedia.ca/Amarillo-Hotels-Country-Inn-Suites-By-Radisson.h1183905.Hotel-Information) 2 km from Don and Sybil Harrington Cancer Center 9.0/10 Wonderful (2,457 reviews) "Great staff, excellent room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raymond CA $99 CA $114 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Amarillo-Hotels-Country-Inn-Suites-By-Radisson.h1183905.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/113000000/112080000/112075500/112075474/0275d51b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112080000/112075500/112075474/9b394468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/113000000/112080000/112075500/112075474/21d77496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/113000000/112080000/112075500/112075474/d38dc56f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Everhome Suites Amarillo West - Medical Center [](https://www.expedia.ca/Amarillo-Hotels-Everhome-Suites.h112075474.Hotel-Information) 1.2 km from Don and Sybil Harrington Cancer Center 8.8/10 Excellent (123 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tyler CA $140 CA $161 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Amarillo-Hotels-Everhome-Suites.h112075474.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/50000/43000/42977/fd9afff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/43000/42977/6fde0130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43000/42977/c9af37c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/50000/43000/42977/469d0a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Amarillo West/Medical Center [](https://www.expedia.ca/Amarillo-Hotels-Fairfield-Inn-Suites-Amarillo-WestMedical-Center.h42977.Hotel-Information) 1 km from Don and Sybil Harrington Cancer Center 8.4/10 Very good (756 reviews) "Very nice and helpful staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alicia CA $124 CA $145 total includes taxes & fees Jan 17 - Jan 18 [](https://www.expedia.ca/Amarillo-Hotels-Fairfield-Inn-Suites-Amarillo-WestMedical-Center.h42977.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1060000/1050300/1050235/5678ae14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1060000/1050300/1050235/5a02847e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1060000/1050300/1050235/c6cfbf8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050300/1050235/bfc51109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Amarillo [](https://www.expedia.ca/Amarillo-Hotels-Homewood-Suites-By-Hilton-Amarillo.h1050235.Hotel-Information) 2.2 km from Don and Sybil Harrington Cancer Center 8.8/10 Excellent (1,001 reviews) "Very clean, friendly staff, good breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deanna CA $97 CA $111 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Amarillo-Hotels-Homewood-Suites-By-Hilton-Amarillo.h1050235.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/802200/802113/be66e00d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/810000/802200/802113/3f90f0e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/810000/802200/802113/b209a3e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/810000/802200/802113/54680b6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Amarillo West near Medical Center [](https://www.expedia.ca/Amarillo-Hotels-Comfort-Inn-And-Suites-Amarillo.h802113.Hotel-Information) 2.2 km from Don and Sybil Harrington Cancer Center 8.6/10 Excellent (1,239 reviews) "Nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $95 CA $109 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Amarillo-Hotels-Comfort-Inn-And-Suites-Amarillo.h802113.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/108000000/107250000/107247300/107247238/a2af94ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/108000000/107250000/107247300/107247238/c05ee3f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/108000000/107250000/107247300/107247238/7c254ee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/108000000/107250000/107247300/107247238/624f8556.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites By Wyndham Amarillo West [](https://www.expedia.ca/Amarillo-Hotels-Microtel-Inn-Suites-By-Wyndham-Amarillo-West.h107247238.Hotel-Information) 2.1 km from Don and Sybil Harrington Cancer Center 8.6/10 Excellent (622 reviews) "Enjoyed our stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank CA $110 CA $126 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Amarillo-Hotels-Microtel-Inn-Suites-By-Wyndham-Amarillo-West.h107247238.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3060000/3050100/3050054/a29ea4af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3060000/3050100/3050054/3577d417.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/4000000/3060000/3050100/3050054/90d5b9f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/4000000/3060000/3050100/3050054/a11e4def.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites West Medical Center [](https://www.expedia.ca/Amarillo-Hotels-Sleep-Inn-Suites-West-Medical-Center.h3050054.Hotel-Information) 1.1 km from Don and Sybil Harrington Cancer Center 8.2/10 Very good (1,001 reviews) "The staff was incredible from the moment we got there. They were helpful in anything we needed. We enjoyed the hot tub and the breakfast and everything was clean! Great place to stay and would again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shaun CA $86 CA $99 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/Amarillo-Hotels-Sleep-Inn-Suites-West-Medical-Center.h3050054.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/970000/967300/967219/56080768.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/970000/967300/967219/w3836h2560x4y0-e28ae9d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Beds, Accessible (Hearing)](https://images.trvl-media.com/lodging/1000000/970000/967300/967219/w3837h2556x3y4-dd589196.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/967300/967219/e1b38015.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Amarillo Medical Center [](https://www.expedia.ca/Amarillo-Hotels-Hampton-Inn-Suites-Amarillo-West.h967219.Hotel-Information) 1.1 km from Don and Sybil Harrington Cancer Center 8.0/10 Very good (757 reviews) "Staff was nice and loved the area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Briones CA $90 CA $103 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Amarillo-Hotels-Hampton-Inn-Suites-Amarillo-West.h967219.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4150000/4148500/4148451/e85fc0cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/5000000/4150000/4148500/4148451/40153472.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4150000/4148500/4148451/09b94d78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4150000/4148500/4148451/89ee5370.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Amarillo West Medical Center by IHG [](https://www.expedia.ca/Amarillo-Hotels-Holiday-Inn-Amarillo-West-Medical-Center.h4148451.Hotel-Information) 1.4 km from Don and Sybil Harrington Cancer Center 8.0/10 Very good (1,004 reviews) "Clean, staff are very welcoming and friendly!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth CA $86 CA $99 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Amarillo-Hotels-Holiday-Inn-Amarillo-West-Medical-Center.h4148451.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-28&endDate=2026-01-29®ionId=6080861&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Don and Sybil Harrington Cancer Center Hotel Reviews ![Hyatt Place Amarillo-West](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/1081cf4a_y.jpg) ### Hyatt Place Amarillo-West 10/10 Excellent "The hotel looked brand new. Super clean and super safe. We got in late at night and left the next morning but everything was great. Would definitely stay there again for sure." [](https://expedia.ca/Amarillo-Hotels-Hyatt-Place-Amarillo-West.h44370546.Hotel-Information) ![Holiday Inn Express & Suites Amarillo West by IHG](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/02449019_y.jpg) ### Holiday Inn Express & Suites Amarillo West by IHG 10/10 Excellent "Great large room, very clean. Good location and good breakfast options." [](https://expedia.ca/Amarillo-Hotels-Holiday-Inn-Express-Hotel-Suites-Amarillo-West.h4270804.Hotel-Information) ![Comfort Inn & Suites Amarillo West near Medical Center](https://images.trvl-media.com/lodging/1000000/810000/802200/802113/be66e00d_y.jpg) ### Comfort Inn & Suites Amarillo West near Medical Center 10/10 Excellent "Great staff " [](https://expedia.ca/Amarillo-Hotels-Comfort-Inn-And-Suites-Amarillo.h802113.Hotel-Information) ![Tru By Hilton Amarillo West](https://images.trvl-media.com/lodging/28000000/27240000/27238100/27238096/7988a930_y.jpg) ### Tru By Hilton Amarillo West 10/10 Excellent "Yes" [](https://expedia.ca/Amarillo-Hotels-Tru-By-Hilton-Amarillo-West.h27238096.Hotel-Information) ![Country Inn & Suites by Radisson, Amarillo I-40 West, TX](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/0abb04c2_y.jpg) ### Country Inn & Suites by Radisson, Amarillo I-40 West, TX 10/10 Excellent "We stayed at Countryside primarily because we were traveling with our pet dog, a Labrador retriever. We had been told that the hotel was pet friendly, and were not disappointed. The hotel staff and management were accommodating, seemingly due to our dedication to being responsible pet owners. We will stay there again if need be in the future. " [](https://expedia.ca/Amarillo-Hotels-Country-Inn-Suites-By-Radisson.h1183905.Hotel-Information) ![La Quinta Inn by Wyndham Amarillo West Medical Center](https://images.trvl-media.com/lodging/1000000/20000/16400/16396/1f7b2acf_y.jpg) ### La Quinta Inn by Wyndham Amarillo West Medical Center 10/10 Excellent "Yes" [](https://expedia.ca/Amarillo-Hotels-La-Quinta-Inn-By-Wyndham-Amarillo-West-Medical-Center.h16396.Hotel-Information) ![Best Western Plus Medical Center](https://images.trvl-media.com/lodging/33000000/32460000/32451100/32451099/e3bc6adf_y.jpg) ### Best Western Plus Medical Center 10/10 Excellent "Hotel looks new. Towels were white. Facility was spotless. Breakfast was good. I felt safe here and was encouraged by no noise, large room, well thought accommodations, and quick check in. " [](https://expedia.ca/Amarillo-Hotels-Best-Western-Plus-Medical-Center.h32451099.Hotel-Information) ![Studio 6 Suites Amarillo, Tx – West Medical Center](https://images.trvl-media.com/lodging/104000000/103290000/103289600/103289535/ef1f0ca2_y.jpg) ### Studio 6 Suites Amarillo, Tx – West Medical Center 10/10 Excellent "Parkin" [](https://expedia.ca/Amarillo-Hotels-Studio-6-Suites-Amarillo.h103289535.Hotel-Information) ![Drury Inn & Suites Amarillo](https://images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/887f87c2_y.jpg) ### Drury Inn & Suites Amarillo 10/10 Excellent "Great desk clerk. The free dinner buffet with multiple beverages was a special first ever treat for us. The breakfast buffet was also very nice. Clean room. Top notch place. If all Drury Inns are this nice, I should be using you more." [](https://expedia.ca/Amarillo-Hotels-Drury-Inn-Suites-Amarillo.h1529725.Hotel-Information) ## Hotels near other Don and Sybil Harrington Cancer Center attractions ### Amarillo Botanical Gardens 4.2/5 (122 reviews) Explore the great outdoors at Amarillo Botanical Gardens, a lovely green space in Amarillo. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6080835) ### Don Harrington Discovery Center You can spend an afternoon studying the exhibits at Don Harrington Discovery Center during your trip to Amarillo. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6080863) ### Helium Monument Learn about the local history of Amarillo when you spend time at Helium Monument. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6080869) ### Westgate Mall 4.0/5 (453 reviews) You can find the perfect gifts to bring home at Westgate Mall during your visit to Amarillo. Discover the top-notch restaurants and entertainment choices in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6080887) ### Shops At Soncy You can find the perfect gifts to bring home at Shops At Soncy during your visit to Amarillo. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=875843302866583552) ### The Galleries at Sunset Center You can spend an afternoon exploring the galleries in The Galleries at Sunset Center during your trip to Amarillo. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561866782) ### Wildcat Bluff Nature Center You can learn about the history of Amarillo when you stop by Wildcat Bluff Nature Center. Attend a sporting event while in this family-friendly area or simply enjoy the charming coffeehouses. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532645855) ### Amarillo National Tennis Center Catch an event at Amarillo National Tennis Center during your trip to Amarillo. Experience the entertainment choices or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941623937056497664) ## Frequently asked questions ### What's the area like around Don and Sybil Harrington Cancer Center? ### What's the best place to stay near Don and Sybil Harrington Cancer Center? ### How many hotels can I expect to find near Don and Sybil Harrington Cancer Center? ### If I need to cancel the hotel reservation for my stay near Don and Sybil Harrington Cancer Center, will I receive a refund? ### What can I see and do near Don and Sybil Harrington Cancer Center? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - [5 Star Hotels in Amarillo ](https://www.expedia.ca/5Star-Amarillo-Hotels.s50-0-d371.Travel-Guide-Filter-Hotels) - [Aparthotels in Amarillo ](https://www.expedia.ca/Amarillo-Apart-Hotels.d371-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Amarillo ](https://www.expedia.ca/Amarillo-Apartments.d371-aaApartments.Travel-Guide-Accommodation) - 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