Title: Top Hotels in Misiones Department | Expedia.ca [Vacation Rentals in Misiones Department](https://expedia.ca/Destinations-In-Misiones-Department.d553248635975177264.Vacation-Rental-Destinations)[Misiones Department Car Rentals](https://expedia.ca/Destinations-In-Misiones-Department.d553248635975177264.Car-Rental-Destinations)[Misiones Department Vacations](https://expedia.ca/Misiones-Department.d553248635975177264.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 1 - Mar 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975177264&startDate=2026-03-01&endDate=2026-03-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 2 - Mar 3](https://www.expedia.ca/Hotel-Search?regionId=553248635975177264&startDate=2026-03-02&endDate=2026-03-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=553248635975177264&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=553248635975177264&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. 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[Book now](https://expedia.ca/deals?rfrr=HTG_SPRING_PROMO_553248635975177264) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Misiones-Department.d553248635975177264.Hotel-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Misiones-Department.d553248635975177264.Hotel-Destinations) ## Top Misiones Department Hotel Reviews ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Misiones Department - [Ayolas Hotels ](https://expedia.ca/Ayolas-Hotels.d3000472762.Travel-Guide-Hotels) - [Santa Rosa Hotels ](https://expedia.ca/Santa-Rosa-Hotels.d3000379166.Travel-Guide-Hotels) - [Santiago Hotels ](https://expedia.ca/Santiago-Hotels.d3000478258.Travel-Guide-Hotels) ### Expedia's Latest Trends Hotels - [Beach Hotel in São Paulo State](https://expedia.ca/Destinations-In-Sao-Paulo-State-Beach-Hotel.0-0-d6052648-tBeachHotel.Hotel-Filter-Destinations) - [Hotels in Guaira Department](https://expedia.ca/Destinations-In-Guaira-Department.d3000429879.Hotel-Destinations) - [Hotels in Galápagos](https://expedia.ca/Destinations-In-Galapagos.d1371.Hotel-Destinations) - [Family Hotels in Florida](https://expedia.ca/Destinations-In-Florida-Family-Hotel.0-0-d6278083-tFamilyHotel.Hotel-Filter-Destinations) - [All Inclusive Resorts and Hotels in Rio de Janeiro State](https://expedia.ca/Destinations-In-Rio-De-Janeiro-State-All-Inclusive-Hotel.0-0-d6052641-tAllInclusiveHotel.Hotel-Filter-Destinations) - [All Inclusive Resorts and Hotels in São Paulo State](https://expedia.ca/Destinations-In-Sao-Paulo-State-All-Inclusive-Hotel.0-0-d6052648-tAllInclusiveHotel.Hotel-Filter-Destinations) - [All Inclusive Resorts and Hotels in Cusco Region](https://expedia.ca/Destinations-In-Cusco-Region-All-Inclusive-Hotel.0-0-d6235224-tAllInclusiveHotel.Hotel-Filter-Destinations) - [All Inclusive Resorts and Hotels in Galápagos](https://expedia.ca/Destinations-In-Galapagos-All-Inclusive-Hotel.0-0-d1371-tAllInclusiveHotel.Hotel-Filter-Destinations) Flights - [Cheap Flights to Galápagos](https://expedia.ca/Destinations-In-Galapagos.d1371.Flight-Destinations) - [Cheap Flights to Florida](https://expedia.ca/Destinations-In-Florida.d6278083.Flight-Destinations) Cruises - [Cruises to Galápagos](https://expedia.ca/Cruises-to-Galapagos.d1371.Travel-Guide-Cruise) Activities - [Things to do in Quindío](https://expedia.ca/Things-To-Do-In-Quindio.d6238702.Travel-Guide-Activities) - [Things to do in Valle del Cauca](https://expedia.ca/Things-To-Do-In-Valle-Del-Cauca.d6238734.Travel-Guide-Activities) Packages - [Galápagos All-inclusive Vacation Packages](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations/1371/Galapagos) - [Galápagos Vacations](https://expedia.ca/Galapagos.d1371.Destination-Travel-Guides) General - [Visit Neuquén](https://expedia.ca/Neuquen.dx3000655715) - [Visit Cundinamarca](https://expedia.ca/Cundinamarca.dx6238682) - [Visit Santa Catarina](https://expedia.ca/Santa-Catarina.dx6052646) - [Visit Formosa Province](https://expedia.ca/Formosa-Province.dx6232463) - [Visit Buenos Aires Province](https://expedia.ca/Buenos-Aires-Province.dx6054206) - [Visit Jujuy Province](https://expedia.ca/Jujuy-Province.dx6232492) - [Visit Rio Grande do Sul](https://expedia.ca/Rio-Grande-Do-Sul.dx6052643) - [Visit Magallanes y Antartica Chilena](https://expedia.ca/Magallanes-Y-Antartica-Chilena.dx6236290) - [Visit La Guajira](https://expedia.ca/La-Guajira.dx6238675) - [Visit Entre Ríos Province](https://expedia.ca/Entre-Rios-Province.dx6232337) - [Visit La Pampa Province](https://expedia.ca/La-Pampa-Province.dx6232299) - [Visit San Andrés y Providencia](https://expedia.ca/San-Andres-Y-Providencia.dx6226974) - [Visit Valle del Cauca](https://expedia.ca/Valle-Del-Cauca.dx6238734) - [Visit Chubut Province](https://expedia.ca/Chubut-Province.dx6232240) - [Visit Antofagasta Region](https://expedia.ca/Antofagasta-Region.dx6236581) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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