Title: Book The Best Hotels in Clarksdale, MO for 2026 from CA $96 - Fully Refundable Options - Expedia.ca [Clarksdale Travel Guide](https://expedia.ca/Clarksdale.dx553248634983445286)[Vacation Rentals in Clarksdale](https://expedia.ca/Clarksdale-Vacation-Rentals.d553248634983445286.Travel-Guide-VacationRentals)[Clarksdale Car Rentals](https://expedia.ca/Car-Rentals-In-Clarksdale.d553248634983445286.Car-Rental-Guide)[Clarksdale Vacation Packages](https://expedia.ca/Clarksdale.d553248634983445286.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Clarksdale, MO from CA $96 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Clarksdale Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=POOL) Cabin [](https://www.expedia.ca/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&lodging=CABIN) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=HOT_TUB) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=PETS) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&lodging=APARTMENT) ## Check prices for these dates Tonight [Jan 9 - Jan 10](https://www.expedia.ca/Hotel-Search?regionId=553248634983445286&startDate=2026-01-09&endDate=2026-01-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 10 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248634983445286&startDate=2026-01-10&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248634983445286&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=553248634983445286&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Clarksdale hotels ![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/85cb1016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/27251199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/965f4dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/a59c6aa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cameron [](https://www.expedia.ca/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information) Cameron 8.4/10 Very good (626) "Surprisingly quite next to the interstate. Older hotel, but still has some charm. Breakfast, customer service and the rooms were nice. My family and I enjoyed our stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly CA $129 CA $143 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8254b815.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/923f99c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/b90af532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn St. Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information) St. Joseph 8.2/10 Very good (662) "A great place to stay-clean and friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason CA $123 CA $142 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/cc53b139.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/dc26a342.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds (Smoke Free)](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/538cff90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Cameron [](https://www.expedia.ca/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information) Cameron 8.8/10 Excellent (1001) "Clean room and friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica [](https://www.expedia.ca/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/ce15b185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/15777d71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/2dd83c29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) St. Joseph 9.4/10 Exceptional (1000) "Great place to stay in St. Joseph. Always a clean room, good breakfast and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) melissa CA $139 CA $160 total includes taxes & fees Jan 16 - Jan 17 [](https://www.expedia.ca/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/d40daa76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/71deeec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/55bf67a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites St. Joseph by IHG [](https://www.expedia.ca/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) St. Joseph 9.2/10 Wonderful (795) "Cleanliness, kind and courteous staff, good hot breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily CA $140 CA $162 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/33a09121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/da4c15cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/29a35617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### My Place Hotel St Joseph MO [](https://www.expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) St. Joseph 9.2/10 Wonderful (213) "This place was very convenient for us and very clean and staff were very friendly and helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sue CA $111 CA $128 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/574523e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/30b33635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton St. Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information) St. Joseph 9.2/10 Wonderful (94) "Great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcella M CA $158 CA $183 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/cdd2480a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/602776a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/eea04022.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/9fa0a9ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Cameron [](https://www.expedia.ca/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information) Cameron 7.6/10 Good (830) "Easy to locate, quiet, room was clean, breakfast was OK" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicki CA $95 CA $105 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/a2399256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/80e80506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/60106125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Cameron [](https://www.expedia.ca/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information) Cameron 8.2/10 Very good (1000) "The room was very clean, staff were very good and the breakfast is up to the task to do it there instead of elsewhere. It's way more better than the usual, cereal and toast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $97 CA $106 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/b42a1684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/2dbfeb6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/7977062c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/f5217c79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott St. Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) St. Joseph 9.6/10 Exceptional (473) "Clean room and friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerome CA $146 CA $170 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/31b1c36c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/6001dbbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/3ffb20d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/e4a9e9ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Cameron, MO [](https://www.expedia.ca/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information) Cameron 7.0/10 Good (288) "Very clean and comfortable. Great staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $92 CA $102 total includes taxes & fees Jan 10 - Jan 11 [](https://www.expedia.ca/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/d807d6a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/0938fa17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/132d826f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free valet parking](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/abdbbdba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capri Motel By OYO Elwood, Wathena [](https://www.expedia.ca/Wathena-Hotels-Capri-Motel-By-OYO-Elwood.h108195771.Hotel-Information) Wathena [](https://www.expedia.ca/Wathena-Hotels-Capri-Motel-By-OYO-Elwood.h108195771.Hotel-Information) ![Room, 1 King Bed, Hot Tub](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fd3d7861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/3d5ca308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/d3b97e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Cameron [](https://www.expedia.ca/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information) Cameron 8.4/10 Very good (642) "Very clean and friendly staff. Nice place!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dean CA $107 CA $118 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/82c1711e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/64e61c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/f4de68bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/2de574ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stoney Creek Hotel St. Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) St. Joseph 9.0/10 Wonderful (1584) "Great staff and amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary CA $139 CA $161 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/bd099a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/cffb314f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, Ensuite (Single Queen ) | Bathroom](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/3259f00c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/w1000h963x0y0-b16dd7a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Whiskey Mansion [](https://www.expedia.ca/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information) St. Joseph 9.2/10 Wonderful (588) "Bueatiful home, clean, quiet and fantastic service and food!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ellie CA $186 CA $216 total includes taxes & fees Jan 23 - Jan 24 [](https://www.expedia.ca/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/86578d4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/f76ef679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/8fa32ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/f4c6728d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vineyard Mansion & Carriage House Bed & Breakfast [](https://www.expedia.ca/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information) St. Joseph 9.0/10 Wonderful (198) "Enjoyed our stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vincent CA $148 CA $218 total includes taxes & fees Jan 10 - Jan 11 [](https://www.expedia.ca/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/683baa8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/d13708b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Smoking, Ground Floor](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/65898125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/7ac0c126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Cameron [](https://www.expedia.ca/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information) Cameron 6.0/10 (159) "Lovely staff. Very helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colleen CA $96 CA $106 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information) ![Premium bedding, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/9d51d430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/10d352cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/b3fa2b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/6328c1ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmeriStay Inn [](https://www.expedia.ca/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information) St. Joseph 5.4/10 (701) "Always friendly staff and clean quiet rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacob [](https://www.expedia.ca/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information) ![Deluxe Apartment, 3 Bedrooms, Park View | Park view](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/f105b4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 3 Bedrooms, Park View | Living area](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/e4bcc2ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 3 Bedrooms, Park View | In-room dining](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/9ed1ca1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 3 Bedrooms, Park View](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/w4032h2718x0y306-05e60f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cameron Suites [](https://www.expedia.ca/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information) Cameron CA $152 CA $305 total includes taxes & fees Jan 10 - Jan 11 [](https://www.expedia.ca/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/99c39a58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/183e59b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/f979dca9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/cf8f0300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Saint Joseph, MO [](https://www.expedia.ca/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information) St. Joseph 4.6/10 (1002) "Staff was very nice, very clean, pet friendly. Will definitely stay here again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda CA $83 CA $96 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-23&endDate=2026-01-24®ionId=553248634983445286&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FClarksdale-Hotels.d553248634983445286.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FClarksdale-Hotels.d553248634983445286.Travel-Guide-Hotels) ## More cheap stays in Clarksdale ![Days Inn by Wyndham Cameron](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/602776a9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Cameron 601 E. Bryan Road Cameron MO CA $95 CA $105 total Jan 18 - Jan 19 includes taxes & fees 7.6/10 Good! (830 reviews) [](https://expedia.ca/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information) ![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### My Place Hotel St Joseph MO 3621 N Village Dr St. Joseph MO CA $111 CA $128 total Jan 18 - Jan 19 includes taxes & fees 9.2/10 Wonderful! (212 reviews) [](https://expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) ![Hampton Inn St. Joseph](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn St. Joseph 3928 Frederick Ave St. Joseph MO CA $123 CA $142 total Jan 18 - Jan 19 includes taxes & fees 8/10 Very Good! (662 reviews) [](https://expedia.ca/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information) ![Holiday Inn Express Hotel & Suites St. Joseph by IHG](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites St. Joseph by IHG 3600 N. Village Dr. St. Joseph MO CA $140 CA $162 total Jan 30 - Jan 31 includes taxes & fees 9/10 Wonderful! (795 reviews) [](https://expedia.ca/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) ![Fairfield Inn & Suites by Marriott St. Joseph](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/f5217c79_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott St. Joseph 4779 Tuscany Drive St. Joseph MO CA $146 CA $170 total Jan 18 - Jan 19 includes taxes & fees 9.6/10 Exceptional! (473 reviews) [](https://expedia.ca/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) ![Red Roof Inn Cameron](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Red Roof Inn Cameron 501 Northland Drive Cameron MO [Get rates](https://expedia.ca/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=39991&PinnedHotelID=39991&HadPinnedHotel=true®ionId=553248634983445286) 8.6/10 Excellent! (1,000 reviews) [](https://expedia.ca/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information) ## Hotels in Clarksdale with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 6 properties [](https://expedia.ca/3Star-Clarksdale-Hotels.s30-0-d553248634983445286.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 27 properties [](https://expedia.ca/2Star-Clarksdale-Hotels.s20-0-d553248634983445286.Travel-Guide-Filter-Hotels) ## Recent reviews of Clarksdale hotels ![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg) ### My Place Hotel St Joseph MO 5/5 Excellent "Room was very clean. Staff helped with 2 minor issues I had and went out of their way to fix my issue." A verified traveller stayed at My Place Hotel St Joseph MO Posted 1 day ago [](https://expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) ![Fairfield Inn & Suites by Marriott St. Joseph](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/f5217c79_y.jpg) ### Fairfield Inn & Suites by Marriott St. Joseph 5/5 Excellent "Clean room and friendly staff. " A verified traveller from Rolla stayed at Fairfield Inn & Suites by Marriott St. Joseph Posted 3 days ago [](https://expedia.ca/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) ![SureStay Hotel by Best Western Cameron](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/b317db33_y.jpg) ### SureStay Hotel by Best Western Cameron 5/5 Excellent "Excellent breakfast, parked right outside our door. " A verified traveller stayed at SureStay Hotel by Best Western Cameron Posted 4 days ago [](https://expedia.ca/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information) ![Super 8 by Wyndham Cameron](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4_y.jpg) ### Super 8 by Wyndham Cameron 5/5 Excellent "We appreciated an easy stop during a long road trip." A verified traveller stayed at Super 8 by Wyndham Cameron Posted 5 days ago [](https://expedia.ca/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information) ![Hampton Inn St. Joseph](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8_y.jpg) ### Hampton Inn St. Joseph 5/5 Excellent "Nice" A verified traveller stayed at Hampton Inn St. Joseph Posted 5 days ago [](https://expedia.ca/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information) ![Drury Inn & Suites St Joseph](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/2dd83c29_y.jpg) ### Drury Inn & Suites St Joseph 5/5 Excellent "Nice clean rooms with comfy beds. The staff was lovely. " A verified traveller stayed at Drury Inn & Suites St Joseph Posted 5 days ago [](https://expedia.ca/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) ![Days Inn by Wyndham Cameron](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/602776a9_y.jpg) ### Days Inn by Wyndham Cameron 5/5 Excellent "A good choice for a reasonable price. " A verified traveller stayed at Days Inn by Wyndham Cameron Posted 6 days ago [](https://expedia.ca/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information) ![Stoney Creek Hotel St. Joseph](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/342fa799_y.jpg) ### Stoney Creek Hotel St. Joseph 5/5 Excellent "This place was very accommodating they offered early check in at no cost and let my wife and i stay till 4 with late check out and on top of that i had a hiccup with my air b&b for the night and they were able to roll over my room at my current rate great staff the breakfast was great the pancake machine is a cool option they had fresh fruit eggs and sausage as well as many bread options and condiments to choose from would recommend this place to all 5 stars " A verified traveller stayed at Stoney Creek Hotel St. Joseph Posted 6 days ago [](https://expedia.ca/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) ![Whiskey Mansion](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/81b46103_y.jpg) ### Whiskey Mansion 5/5 Excellent "Very much liked the Victorian construction of this house. The caretaker was very helpful and gracious … and most especially we liked the wonderful breakfast she prepared on the two days we were there … Thank you very much … 👍🙂😊" A verified traveller stayed at Whiskey Mansion Posted 8 days ago [](https://expedia.ca/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information) ## Frequently asked questions ### Where is the best place to stay in Clarksdale? ### What are some of the best vacation home rentals that Clarksdale has to offer? ### If I need to cancel my hotel reservation in Clarksdale, will I receive a refund? ### What is staying in Clarksdale like? ### What should I do while I'm visiting Clarksdale? ### What's the seasonal weather like in Clarksdale? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [5 Star Hotels in Cameron ](https://www.expedia.ca/5Star-Cameron-Hotels.s50-0-d6533.Travel-Guide-Filter-Hotels) - [Condo Rentals in Agency ](https://www.expedia.ca/Agency-Condos.d553248634983462091-aaCondos.Travel-Guide-Accommodation) - 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