Title: Panama Car Rental, IL - Search & Compare - Expedia.ca​ [Panama Travel Guide](https://expedia.ca/Panama.dx553248634983528718)[Hotels in Panama](https://expedia.ca/Panama-Hotels.d553248634983528718.Travel-Guide-Hotels)[Flights to Panama](https://expedia.ca/Cheap-Flights-To-Panama.d553248634983528718.Travel-Guide-Flights)[Panama Vacation Packages](https://expedia.ca/Panama.d553248634983528718.Destination-Travel-Guides) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Panama Car Rental ## Search and Compare from Car Companies in Panama ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXCA-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself Members save 10% or more on over 1 million car rentals - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers to unlock big savings ## Top Car Deals in Panama \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Panama, Illinois, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Panama,%20Illinois,%20United%20States%20of%20America&dpln=553248634983528718&date1=24/02/2026&date2=26/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Panama, Illinois, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Panama,%20Illinois,%20United%20States%20of%20America&dpln=553248634983528718&date1=24/02/2026&date2=26/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Panama, Illinois, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Panama,%20Illinois,%20United%20States%20of%20America&dpln=553248634983528718&date1=24/02/2026&date2=26/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Panama, Illinois, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Panama,%20Illinois,%20United%20States%20of%20America&dpln=553248634983528718&date1=24/02/2026&date2=26/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car rentals in Panama [View all cars](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Panama,%20Illinois,%20United%20States%20of%20America&dpln=553248634983528718&date1=24/02/2026&date2=26/02/2026&crfrr=defaultFlex&SearchType=Place) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=CTG_SPRING_PROMO_553248634983528718) ## Frequently asked questions ### How much is a rental car per day in Panama? ### What happens if I need to cancel my Panama car reservation? ### Where can I go on a road trip from Panama? > - Make tracks to St. Louis for a fantastic sightseeing experience. Around 72 kilometres from Panama, it's home to many inspiring sights like Busch Stadium. > - Your next pit stop? Consider St. Charles, which is around 88 kilometres away. Ameristar Casino St. Charles is one local highlight you shouldn't miss. > - Head to Starved Rock State Park to rediscover nature. Take a picnic to enjoy or just recharge your batteries in the fresh air. From Panama, it's approximately 257 kilometres away. ### How do I find the best car rental deals in Panama with Expedia? ### How old do you have to be to rent a car in Panama? ### What do you need to rent a car in Panama? ### What is the cheapest car rental in Panama? ### Can I rent a car for a month or longer in Panama? ### Where can I find a Panama car rental if I am younger than 25? ## Car Rental Information | Popular car types: | [SUV](https://www.expedia.ca/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.ca/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.ca/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.ca/ground-transfers?rfrr=car.table.AirportTransportation) | ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app