Antofagasta Region Vacation Packages

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Top vacation destinations in Antofagasta Region

A narrow dirt road lined with buildings and trees, with people walking and a stroller visible.

San Pedro de Atacama

San Pedro de Atacama
A desert beach with a mountain in the background.

Antofagasta

Antofagasta
A vast desert landscape with rugged mountains in the background.

Calama

Calama

Top Antofagasta Region Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Casa Solcor

Casa Solcor

CA $635
per person
Oct 4 - Oct 7
found 6 hours ago
Roundtrip flight included
Santiago (SCL) to Calama (CJC)
9.8/10 Exceptional! (63 reviews)
Everything was wonderful. Beautifully curated property, with very friendly and helpful staff. My family of 7 really enjoyed our time.

Reviewed on Aug 2, 2026

Noi Casa Atacama

Noi Casa Atacama

CA $682
per person
Oct 4 - Oct 7
found 6 hours ago
Roundtrip flight included
Santiago (SCL) to Calama (CJC)
8.8/10 Excellent! (276 reviews)
Tierra Atacama, Beckons

Tierra Atacama, Beckons

CA $4,172
per person
Oct 4 - Oct 7
found 6 hours ago
Roundtrip flight included
Santiago (SCL) to Calama (CJC)
9.8/10 Exceptional! (69 reviews)
Hotel Desertica

Hotel Desertica

CA $853
per person
Oct 4 - Oct 7
found 6 hours ago
Roundtrip flight included
Santiago (SCL) to Calama (CJC)
9.8/10 Exceptional! (134 reviews)
A beautiful hotel in a great location. Very friendly staff. The rooms were really beautiful and wonderfully decorated and the hotel restaurant food was delicious. Wish we could have stayed longer!

Reviewed on Jul 22, 2026

Hotel Terrantai

Hotel Terrantai

CA $983
per person
Oct 4 - Oct 7
found 6 hours ago
Roundtrip flight included
Santiago (SCL) to Calama (CJC)
9.4/10 Exceptional! (322 reviews)
Location was amazing. I was originally worried that it would be noisy because it’s so central, but it was quiet. The staff were AMAZING! I chatted with Christian a lot which made me change up our itinerary a little bit and it was definitely for the best. The pool was bit too cold for me since we went in May (felt like a cold plunge the one time I went), but it was still nice to lay out. Absolutely recommend this location.

Reviewed on May 30, 2026

Antofagasta Region Hotel Deals

Diego de Almagro San Pedro de Atacama

Diego de Almagro San Pedro de Atacama

Toconao 460 San Pedro de Atacama Antofagasta
Fully refundableReserve now, pay when you stay
CA $158
CA $158 total
Aug 10 - Aug 11
8.2/10 Very good! (400 reviews)
"Staff very helpful and friendly, although no English. Happy to converse using translation tools. Swimming pool was closed due to it being winter, which I didn’t reslise when I booked. A couple of times there was no water, no electricity and no wifi, but staff worked to resolve the issue. Breakfast ..."

Reviewed on Jul 18, 2026

Diego de Almagro San Pedro de Atacama
Hotel La Casa de Don Tomas

Hotel La Casa de Don Tomas

Calle Tocopilla Sitio 18 San Pedro de Atacama
Fully refundableReserve now, pay when you stay
CA $293
CA $293 total
Aug 9 - Aug 10
9.2/10 Wonderful! (431 reviews)
"The hotel staff are so helpful. Very attentive. Great view of the mountains and volcano from the room. Very peaceful and tranquil."

Reviewed on Jul 30, 2026

Hotel La Casa de Don Tomas
Geotel Calama

Geotel Calama

Cobija 2273 Calama Antofagasta
CA $101
CA $101 total
Aug 9 - Aug 10
8.8/10 Excellent! (235 reviews)
"Reservation for 1 Double 2 bedrooms apartment. Changed for 2 singles. Heather non-working. Breakfast to.go offered but Non ready when leaving."

Reviewed on Jul 29, 2026

Geotel Calama
See all 322 properties in Antofagasta Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Antofagasta Region vacation package cost?
From as low as CA $635. Yes, you read that right. Our Antofagasta Region packages are the best way to stretch your budget. Combine your hotels, flights and car rentals and discover this lively destination.
How do I get a cheap travel package to Antofagasta Region?
Our Antofagasta Region vacation packages promise plenty of savings for the savvy traveler. For the best deals, simply bundle your hotel, flights and activities into an affordable package. But impressive bargains are only the start of your next unforgettable adventure. Book with Expedia and you'll have more than 550 airlines and 1,000,000 properties throughout the world to pick from. Whatever your budget, there's a package that's perfect for you.
What are the top hotels in Antofagasta Region?
Have a look at ibis Antofagasta and NH Antofagasta. They're the first choice for lots of travelers to Antofagasta. If San Pedro de Atacama is on your travel itinerary, Park Hotel Calama and Noi Casa Atacama are cozy options.
How far in advance should I book my Antofagasta Region vacation?
It can be tricky to know when is the ideal time to book your trip to Antofagasta Region. But typically the earlier you book, the better the prices. Sometimes, you can reserve your flights and hotels up to a year before your departure date. If you're considering a last-minute getaway, no need to stress! There are fabulous deals featured on Expedia every single day.
What does an Expedia Antofagasta Region travel package include?
From hotels and airfares to rental cars, Expedia can help you shape an Antofagasta Region package that's perfect for you. Vacationing for a week or two? Consider a rental car, hotel and flight bundle. If you're taking a short break, a flight and hotel deal could be more your style. Activities can also be added once you've made your booking. Our vacation packages make it simple to save and plan.
What should I know before booking an Antofagasta Region travel package?
Tailor deals to suit your budget with an Expedia package. Airfares, hotels, rental cars — we're a one-stop shop for all of them. You'll save precious dollars just for bundling your bookings. Whether you're embarking on a skiing adventure or drinking cocktails on a beach, your perfect getaway is just clicks away.
Can I choose my airline with an Antofagasta Region Expedia vacation package?
Expedia has access to more than 550 airline partners worldwide, so you sure can! Simply select your preferred carrier and put together the perfect Antofagasta Region trip.
If I'm not able to travel, can I cancel my Antofagasta Region vacation package?
Whether it's your flight or hotel, you can cancel and rebook it. Locked in your Antofagasta Region vacation package in the last 24 hours? You may be able to make changes at no cost. For bookings older than that, you may be charged a fee by your hotel, airline or car rental company. For further information, visit our Customer Service Portal. We'll help you every step of the way.

Stay near popular Antofagasta Region attractions

A desert landscape with layered rock formations and sand dunes.

Valley of the Moon

9.2/10 (244 reviews)
Treat your eyes to the variety of colors in a deserted valley that looks like a scene from a science fiction movie.
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A geothermal area with steam vents, dry grass, and snow-capped mountains in the background.

El Tatio Geysers

9.4/10 (3 reviews)
Commune with nature and explore the great outdoors at El Tatio Geysers during your travels in San Francisco de Chiu Chiu. You can seek out the local tours in this quaint area.
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Plaza de San Pedro de Atacama

8.4/10 (195 reviews)
You can find out about the history of San Pedro de Atacama when you stop by Plaza de San Pedro de Atacama. You can seek out the local tours in this quaint area.
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Mall Plaza Calama

8.8/10 (9 reviews)
During your trip to Calama, you can enjoy retail therapy at Mall Plaza Calama. Discover the area's desert landscape and casinos.
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Piedra del Coyote Overlook

8.8/10 (61 reviews)
Explore the great outdoors at Piedra del Coyote Overlook, a lovely green space in San Pedro de Atacama. You can seek out the local tours in this quaint area.
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Cerro Paranal Observatory

8.6/10 (4 reviews)
Commune with nature and explore the great outdoors at Cerro Paranal Observatory during your travels in Antofagasta. Amble around the area's seaside or visit its shops.
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San Pedro Church

8.6/10 (64 reviews)
San Pedro Church is just one of the places to see in San Pedro de Atacama, so why not enjoy the other things to explore during your travels? You can seek out the local tours in this quaint area.
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Tulor Archaeological Site

8.4/10 (6 reviews)
You can find out about the history of San Pedro de Atacama with a trip to Tulor Archaeological Site. You can seek out the local tours in this quaint area.
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What to do in Antofagasta Region

Astronomical Experience with Astrophotography in Atacama

Astronomical Experience with Astrophotography in Atacama

CA $59
per adult
Astronomical Experience with Astrophotography in Atacama
Tatio Geyser - Atacama

Small-Group Tour to Tatio Geysers Machuca Village & Rio Putana wetlands

CA $111
per adult
Small-Group Tour to Tatio Geysers Machuca Village & Rio Putana wetlands
San Pedro de Atacama: Stargazing Experience with Transfer

San Pedro de Atacama: Stargazing Experience

CA $53
per adult
100% of travellers recommend
San Pedro de Atacama: Stargazing Experience
See all activities in Antofagasta Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.