Title: 5 Stars Hotels in Southern Indiana, United States of America from CA $202 - Find Cheap Southern Indiana Hotels With 5 Stars | Expedia.ca [Southern Indiana Travel Guide](https://expedia.ca/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.ca/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Vacation Rentals in Southern Indiana](https://expedia.ca/Southern-Indiana-Vacation-Rentals.d6059635.Travel-Guide-VacationRentals)[Flights to Southern Indiana](https://expedia.ca/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Southern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Indiana.d6059635.Car-Rental-Guide)[Southern Indiana Vacation Packages](https://expedia.ca/Southern-Indiana.d6059635.Destination-Travel-Guides) ![Kentucky Center for the Performing Arts showing modern architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297198-Kentucky.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Southern Indiana, United States of America from CA $202 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Indiana 5 Star Hotels Tonight [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-10-23&endDate=2025-10-24&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-10-24&endDate=2025-10-25&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-10-31&endDate=2025-11-02&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southern Indiana 5 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Southern-Indiana-Hotels.s50-0-d6059635.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Southern-Indiana-Hotels.s50-0-d6059635.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southern Indiana. ![Galt House Hotel Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Galt House Hotel Trademark Collection by Wyndham 140 North Fourth Street, Louisville, KY CA $195 CA $230 total Nov 22 - Nov 23 includes taxes & fees 8.8/10 Excellent! (3,708 reviews) [](https://expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Omni Louisville Hotel](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Omni Louisville Hotel 400 S. 2nd Street, Louisville, KY CA $279 CA $328 total Nov 15 - Nov 16 includes taxes & fees 9.2/10 Wonderful! (1,649 reviews) [](https://expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Embassy Suites Louisville Downtown](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Embassy Suites Louisville Downtown 501 South Fourth Street, Louisville, KY CA $172 CA $202 total Nov 23 - Nov 24 includes taxes & fees 8.8/10 Excellent! (1,029 reviews) [](https://expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) Still don't see what you're looking for? [See all properties in Southern Indiana.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F10%2F2025&endDate=25%2F10%2F2025®ionId=6059635&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F10%2F2025&endDate=25%2F10%2F2025®ionId=6059635&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F10%2F2025&endDate=25%2F10%2F2025®ionId=6059635&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F10%2F2025&endDate=25%2F10%2F2025®ionId=6059635&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F10%2F2025&endDate=25%2F10%2F2025®ionId=6059635&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F10%2F2025&endDate=25%2F10%2F2025®ionId=6059635&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Southern Indiana Live music, casinos, and top sights like Ohio River Valley—discover it all in Southern Indiana. [See all hotels in Southern Indiana](https://www.expedia.ca/Hotel-Search?startDate=2025-11-06&endDate=2025-11-07&adults=2®ionId=6059635) ![Kentucky Center for the Performing Arts featuring modern architecture](https://images.trvl-media.com/place/6062653/8b326703-a711-4dce-a0ec-21ab55344b9a.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Southern Indiana Hotel Reviews ## Find out more about Southern Indiana Luxury is the name of the game at the best 5 Stars hotels in Southern Indiana. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Southern Indiana 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them. Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Southern Indiana hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Southern Indiana without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Southern Indiana. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Southern Indiana? > There are a range of pricing options for 5-star hotels in Southern Indiana on Expedia. The amount you pay will depend on your travel dates, trip length and other factors. Compare available properties for your desired dates and use our pricing and other filters to score the perfect luxury stay. > > > > - Search for the lowest price per night from CA $202 ### What makes a hotel 5 stars in Southern Indiana? > Exemplary guest service is integral to every 5-star hotel in Southern Indiana. From the moment you arrive, staff attend to your every need, whether arranging valet parking or providing in-room massage treatments. Additionally, hotels must feature upscale amenities to qualify for a 5-star rating. These can include luxury bath products, spas or saunas, swimming pools, gastronomic restaurants and knowledgeable concierge. ### Are there any 5-star all-inclusive resorts in Southern Indiana? > Find a luxurious stay that includes your lodging, meals, bar and entertainment in Southern Indiana with the help of Expedia's filter tool. Search for properties rated 5 stars and click on the "All inclusive" filter. Make sure you check what's included in the price. 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