Title: 5 Stars Hotels in Adrian, Texas  - Find Cheap Adrian Hotels With 5 Stars | Expedia.ca

[Adrian Travel Guide](https://expedia.ca/Adrian.dx3000422512)[Hotels in Adrian](https://expedia.ca/Adrian-Hotels.d3000422512.Travel-Guide-Hotels)[Vacation Rentals in Adrian](https://expedia.ca/Adrian-Vacation-Rentals.d3000422512.Travel-Guide-VacationRentals)[Flights to Adrian](https://expedia.ca/Cheap-Flights-To-Adrian.d3000422512.Travel-Guide-Flights)[Adrian Car Rentals](https://expedia.ca/Car-Rentals-In-Adrian.d3000422512.Car-Rental-Guide)[Adrian Vacation Packages](https://expedia.ca/Adrian.d3000422512.Destination-Travel-Guides)

![Route 66 midpoint sign](https://images.trvl-media.com/place/3000422512/2d6ba6c5-60b8-4e08-9416-59acd9115cc9.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Adrian 5 Star Hotels

Tonight

[Jan 17 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=3000422512&startDate=2026-01-17&endDate=2026-01-18&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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[Jan 18 - Jan 19](https://www.expedia.ca/Hotel-Search?regionId=3000422512&startDate=2026-01-18&endDate=2026-01-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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[Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=3000422512&startDate=2026-01-30&endDate=2026-02-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Learn more about Adrian

At the midpoint of Route 66, stop at the Midpoint Café for their famous 'ugly crust' pies and Route 66 memorabilia. Snap a photo with the town's midway marker, then chat with locals who'll share stories about this tiny highway community.

[See all hotels in Adrian](https://www.expedia.ca/Hotel-Search?startDate=2026-01-31&endDate=2026-02-01&adults=2&regionId=3000422512)

![Route 66 midpoint sign](https://images.trvl-media.com/place/3000422512/2d6ba6c5-60b8-4e08-9416-59acd9115cc9.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

## Top Adrian Hotel Reviews

## Find out more about Adrian

Luxury is the name of the game at the best 5 Stars hotels in Adrian. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Adrian 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them.

Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Adrian hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Adrian without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Adrian.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Adrian?

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### What makes a hotel 5 stars in Adrian?

### Are there any 5-star all-inclusive resorts in Adrian?

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