Title: 2 Stars Hotels in Defiance, St. Louis from CA $96 - Find Cheap Defiance Hotels With 2 Stars | Expedia.ca

[Defiance Travel Guide](https://expedia.ca/Defiance.dx6353634)[Hotels in Defiance](https://expedia.ca/Defiance-Hotels.d6353634.Travel-Guide-Hotels)[Vacation Rentals in Defiance](https://expedia.ca/Defiance-Vacation-Rentals.d6353634.Travel-Guide-VacationRentals)[Flights to Defiance](https://expedia.ca/Cheap-Flights-To-Defiance.d6353634.Travel-Guide-Flights)[Defiance Car Rentals](https://expedia.ca/Car-Rentals-In-Defiance.d6353634.Car-Rental-Guide)[Defiance Vacation Packages](https://expedia.ca/Defiance.d6353634.Destination-Travel-Guides)

![A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Defiance 2 Star Hotels

Tonight

[Mar 8 - Mar 9](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-03-08&endDate=2026-03-09&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 9 - Mar 10](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-03-09&endDate=2026-03-10&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Defiance 2-star hotels

![Lobby](https://images.trvl-media.com/lodging/1000000/60000/55200/55161/40483d14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/60000/55200/55161/996b3c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/1000000/60000/55200/55161/da888317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/60000/55200/55161/7a221d30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn and Suites by Wyndham St. Louis/Westport Plaza

[](https://www.expedia.ca/St-Louis-Hotels-Days-Inn-And-Suites-By-Wyndham-St-LouisWestport-Plaza.h55161.Hotel-Information)

Maryland Heights

4.6/10

(1,005 reviews)

"Everything was good "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Timothy

CA $88

CA $102 total

includes taxes & fees

Mar 10 - Mar 11

[](https://www.expedia.ca/St-Louis-Hotels-Days-Inn-And-Suites-By-Wyndham-St-LouisWestport-Plaza.h55161.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/00255b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/16db26a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/45734724.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/3a2303d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus St. Louis West-Westport

[](https://www.expedia.ca/St-Louis-Hotels-Best-Western-Plus-St-Louis-West-Westport.h41448.Hotel-Information)

Maryland Heights

8.0/10

Very good

(1,054 reviews)

"This place is always good. Been there +10 times."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Federico Gavuzzo

CA $107

CA $125 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/St-Louis-Hotels-Best-Western-Plus-St-Louis-West-Westport.h41448.Hotel-Information)

![Cleanliness standards](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/49b4298c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/864a0b1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/7aa0940e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cleanliness standards](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/8040d847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Relax Inn Saint Charles 

[](https://www.expedia.ca/St-Louis-Hotels-Relax-Inn-Saint-Charles.h1000712.Hotel-Information)

St. Charles

6.8/10

(1,005 reviews)

"Clean room very nice staff it’s nice"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mercedez

CA $83

CA $96 total

includes taxes & fees

Mar 15 - Mar 16

[](https://www.expedia.ca/St-Louis-Hotels-Relax-Inn-Saint-Charles.h1000712.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/1d22ac52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/15695a25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Blackout drapes, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/3b030eed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, Queen Accessible Roll In Shower, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/7c7fdb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn St. Charles St. Peters

[](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information)

St. Charles

8.0/10

Very good

(1,003 reviews)

"Great location and friendly staff "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Heather

CA $138

CA $159 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/001d26f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/0b058bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/0036679a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/254f5b60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Inn & Suites by Radisson, St. Charles Historic District

[](https://www.expedia.ca/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information)

St. Charles Historic District

9.4/10

Exceptional

(1,014 reviews)

"Wonderful place staff awesome "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chad

CA $155

CA $178 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/6093d918.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, Multiple Beds, Non Smoking (2 Queen, 2 Person Sofa Bed)](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/68f10652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/159a98ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/b493e570.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites St Charles - St Louis

[](https://www.expedia.ca/St-Louis-Hotels-Comfort-Suites-St-Charles-St-Louis.h664414.Hotel-Information)

St. Charles

8.4/10

Very good

(1,006 reviews)

"Great hotel for the money"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jere

CA $118

CA $136 total

includes taxes & fees

Mar 15 - Mar 16

[](https://www.expedia.ca/St-Louis-Hotels-Comfort-Suites-St-Charles-St-Louis.h664414.Hotel-Information)

![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/07f8c63c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/5cdbca92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/c413cfac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/f94e59bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sleep Inn & Suites O'Fallon MO - Technology Drive

[](https://www.expedia.ca/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information)

O'Fallon

9.0/10

Wonderful

(1,010 reviews)

"Friendly staff, clean room, comfy bed, excellent breakfast buffet."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kathy

CA $107

CA $127 total

includes taxes & fees

Mar 11 - Mar 12

[](https://www.expedia.ca/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information)

![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/220000/215200/215149/345278af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/220000/215200/215149/aad2ff4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/220000/215200/215149/f64cb47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed with Sofa bed (One Bedroom)](https://images.trvl-media.com/lodging/1000000/220000/215200/215149/89b9b4aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sonesta Simply Suites St Louis Earth City

[](https://www.expedia.ca/St-Louis-Hotels-Sonesta-Simply-Suites-St-Louis-Earth-Cty.h215149.Hotel-Information)

Earth City

8.8/10

Excellent

(843 reviews)

"The rooms were spotless and the staff was great would definitley recommend "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Trish

CA $126

CA $145 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/St-Louis-Hotels-Sonesta-Simply-Suites-St-Louis-Earth-Cty.h215149.Hotel-Information)

![Studio, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/70000/66100/66038/4060a2fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/70000/66100/66038/20cff605.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/70000/66100/66038/0a526cf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/70000/66100/66038/a541015d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Extended Stay America Suites St Louis St Peters

[](https://www.expedia.ca/St-Louis-Hotels-Extended-Stay-America-Suites-St-Louis-St-Peters.h66038.Hotel-Information)

St. Peters

7.0/10

Good

(624 reviews)

"Location was perfect"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tara

CA $117

CA $135 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/St-Louis-Hotels-Extended-Stay-America-Suites-St-Louis-St-Peters.h66038.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/70000/68200/68132/c17520b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/70000/68200/68132/8e7b8531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/70000/68200/68132/a0c491b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/1000000/70000/68200/68132/a7ccae10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Americas Best Value Inn & Suites St. Louis, St. Charles Inn

[](https://www.expedia.ca/St-Louis-Hotels-Americas-Best-Value-Inn-Suites-St-Louis.h68132.Hotel-Information)

St. Charles

5.8/10

(1,004 reviews)

"Great place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christina

CA $122

CA $142 total

includes taxes & fees

Mar 9 - Mar 10

[](https://www.expedia.ca/St-Louis-Hotels-Americas-Best-Value-Inn-Suites-St-Louis.h68132.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16210/55269a5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16210/2adbd684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/16300/16210/2edd84af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16210/34f8e499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Foristell

[](https://www.expedia.ca/Warrenton-Hotels-Quality-Inn.h16210.Hotel-Information)

Foristell

8.2/10

Very good

(947 reviews)

" Clean room friendly staff easy access"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Steve

CA $92

CA $104 total

includes taxes & fees

Mar 22 - Mar 23

[](https://www.expedia.ca/Warrenton-Hotels-Quality-Inn.h16210.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/82000000/81010000/81004400/81004355/9f47a63b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/82000000/81010000/81004400/81004355/6aa343af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/82000000/81010000/81004400/81004355/58885369.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/82000000/81010000/81004400/81004355/5b3b1d88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Extended Stay America Suites - St Louis - Fenton

[](https://www.expedia.ca/St-Louis-Hotels-Extended-Stay-America-Suites-St-Louis-Fenton.h81004355.Hotel-Information)

Fenton

5.8/10

(246 reviews)

"Very friendly "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brad

CA $95

CA $109 total

includes taxes & fees

Mar 15 - Mar 16

[](https://www.expedia.ca/St-Louis-Hotels-Extended-Stay-America-Suites-St-Louis-Fenton.h81004355.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/d446d190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/1d29e551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/b52a585e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/41a6853d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn St. Louis Wentzville

[](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-By-Hilton-Wentzville.h17395579.Hotel-Information)

Wentzville

9.0/10

Wonderful

(666 reviews)

"Prompt service, quick check in. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Emily

CA $162

CA $185 total

includes taxes & fees

Mar 15 - Mar 16

[](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-By-Hilton-Wentzville.h17395579.Hotel-Information)

![43-inch LED TV with digital channels, TV](https://images.trvl-media.com/lodging/1000000/930000/922100/922031/faec28e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 7:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/930000/922100/922031/1d05b896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/930000/922100/922031/dc171dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/930000/922100/922031/7c698b9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites St. Louis - O'Fallon

[](https://www.expedia.ca/St-Louis-Hotels-Comfort-Inn-Suites-St-Louis-OFallon.h922031.Hotel-Information)

O'Fallon

7.6/10

Good

(1,003 reviews)

"Nice room, good front desk help"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

jeffrey

CA $118

CA $140 total

includes taxes & fees

Mar 31 - Apr 1

[](https://www.expedia.ca/St-Louis-Hotels-Comfort-Inn-Suites-St-Louis-OFallon.h922031.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/210000/202300/202216/f60ef45e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/210000/202300/202216/639e641e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/210000/202300/202216/744b055b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Bedrooms](https://images.trvl-media.com/lodging/1000000/210000/202300/202216/393e7ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Candlewood Suites St Louis St Charles by IHG

[](https://www.expedia.ca/St-Louis-Hotels-Towneplace-Suites-By-Marriott-St-Charles.h202216.Hotel-Information)

St. Charles

7.6/10

Good

(785 reviews)

"The staff was very professional and the room was clean. I will definitely book here again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ngozi

CA $114

CA $131 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/St-Louis-Hotels-Towneplace-Suites-By-Marriott-St-Charles.h202216.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/188fac9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/052a5869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/51c38da4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/ac863486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Warrenton

[](https://www.expedia.ca/Warrenton-Hotels-Baymont-By-Wyndham-Warrenton.h124484.Hotel-Information)

Warrenton

7.4/10

Good

(1,003 reviews)

"Nice place and nice people "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Columbus

CA $100

CA $115 total

includes taxes & fees

Mar 9 - Mar 10

[](https://www.expedia.ca/Warrenton-Hotels-Baymont-By-Wyndham-Warrenton.h124484.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/3e0ca2c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/c06ddb8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/b0c1520e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/dbfe312f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express St. Louis West - O'Fallon by IHG

[](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-West-OFallon.h1206489.Hotel-Information)

O'Fallon

8.6/10

Excellent

(876 reviews)

"Service, cleanliness and breakfast were all very agreeable "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

James

CA $118

CA $139 total

includes taxes & fees

Mar 15 - Mar 16

[](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-West-OFallon.h1206489.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/70000000/69650000/69646200/69646123/353d0132.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, free cribs/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/70000000/69650000/69646200/69646123/8bd53911.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/70000000/69650000/69646200/69646123/d84a6664.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/70000000/69650000/69646200/69646123/f79aefe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites St. Charles Old Town Area

[](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-St-Charles-Old-Town-Area.h69646123.Hotel-Information)

St. Charles

9.0/10

Wonderful

(660 reviews)

"Pleasant staff and clean room"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michele

CA $154

CA $186 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-St-Charles-Old-Town-Area.h69646123.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/24000000/23060000/23052900/23052829/5099c288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/24000000/23060000/23052900/23052829/bf6e22bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/24000000/23060000/23052900/23052829/debc97ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/24000000/23060000/23052900/23052829/1cb9d5e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

[](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-Suites-St-Louis-Chesterfield.h23052829.Hotel-Information)

Chesterfield

9.0/10

Wonderful

(1,002 reviews)

"Great hotel!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lorelei

CA $170

CA $197 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-Suites-St-Louis-Chesterfield.h23052829.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/42200/42127/04c6573d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/50000/42200/42127/fbb15b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42127/aa8717f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/42200/42127/0d3776cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Fenton

[](https://www.expedia.ca/St-Louis-Hotels-Best-Western-Plus-Fenton.h42127.Hotel-Information)

Fenton

9.2/10

Wonderful

(222 reviews)

"Stay was great, and the pool was perfect for my daughter and her friend. Wonderful spot for an easy "stay cation" with the girls. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Melissa

CA $124

CA $143 total

includes taxes & fees

Mar 11 - Mar 12

[](https://www.expedia.ca/St-Louis-Hotels-Best-Western-Plus-Fenton.h42127.Hotel-Information)

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## Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Defiance.

![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

1088 South Highway Drive Fenton MO

CA $121

CA $140 total

Mar 9 - Mar 10

includes taxes & fees

8/10 Very Good! (1,118 reviews)

[](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information)

![Hollywood Casino & Hotel St. Louis](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/76ca3207_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hollywood Casino & Hotel St. Louis

777 Casino Center Drive Maryland Heights MO

CA $127

CA $168 total

Apr 1 - Apr 2

includes taxes & fees

8.4/10 Very Good! (2,217 reviews)

[](https://expedia.ca/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information)

![La Quinta Inn & Suites by Wyndham St. Louis Westport](https://images.trvl-media.com/lodging/1000000/70000/62900/62842/2d27fd02_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### La Quinta Inn & Suites by Wyndham St. Louis Westport

11805 Lackland Rd Maryland Heights MO

CA $125

CA $144 total

Apr 5 - Apr 6

includes taxes & fees

7.2/10 Good! (1,108 reviews)

[](https://expedia.ca/St-Louis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-St-Louis-Westport.h62842.Hotel-Information)

Still don't see what you're looking for?

[See all properties in Defiance.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F03%2F2026&endDate=10%2F03%2F2026&regionId=6353634&star=20)

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[Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F03%2F2026&endDate=10%2F03%2F2026&regionId=6353634&star=20&star=20&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F03%2F2026&endDate=10%2F03%2F2026&regionId=6353634&star=20&star=20&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F03%2F2026&endDate=10%2F03%2F2026&regionId=6353634&star=20&star=20&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F03%2F2026&endDate=10%2F03%2F2026&regionId=6353634&star=20&star=20&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F03%2F2026&endDate=10%2F03%2F2026&regionId=6353634&star=20&star=20&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

[See all hotels in Defiance](https://www.expedia.ca/Hotel-Search?startDate=2026-03-22&endDate=2026-03-23&adults=2&regionId=6353634)

![A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high)

## Top Defiance Hotel Reviews

## Find out more about Defiance

Want to get out of town on the cheap? Thanks to the low rates and great discounts at the top 2 Stars hotels in Defiance, Defiance you can sneak away on the trip of your dreams with plenty of cash to spare. In addition to the friendly staff and well-maintained surroundings, you’ll find comfortable rooms, complimentary bath products, and quiet sleeping areas, so you can kick back with all the basic conveniences after a long day. Plus, these properties are perfect, if you need a jumping-off point for exploring the local attractions.

Several of the best hotels with 2 Stars in Defiance are situated just a stone’s throw from both public transportation and the city’s main freeways. Use the travel tools at Expedia.ca to search for options near your favorite neighborhood, find a cheap deal, and book your room. You won’t believe how inexpensive your next vacation can be when you settle in at a top two star hotel in Defiance.

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