A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Cheap Flights to Defiance , MO from CA $168

View CA $168 flight on Fri, Jul 31, 2026Opens in a new window

Popular airlines to Defiance

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How much is the cheapest flight to Defiance?

Prices were available within the past 7 days and start at CA $168 for one-way flights and CA $333 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sat, Aug 15 - Tue, Aug 25
DTW
Detroit
STL
St. Louis
CA $333 Roundtrip, found 1 day ago
CA $333
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Aug 15 from Detroit to St. Louis, returning Tue, Aug 25, priced at CA $333 found 1 day ago
American Airlines
Tue, Jul 14 - Sat, Jul 18
DTW
Detroit
STL
St. Louis
CA $349 Roundtrip, found 6 days ago
CA $349
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Jul 14 from Detroit to St. Louis, returning Sat, Jul 18, priced at CA $349 found 6 days ago
United
Tue, Oct 20 - Mon, Nov 9
YVR
Vancouver
STL
St. Louis
CA $375 Roundtrip, found 12 hours ago
CA $375
Roundtrip
found 12 hours ago
Select United flight, departing Tue, Oct 20 from Vancouver to St. Louis, returning Mon, Nov 9, priced at CA $375 found 12 hours ago
Air Canada
Fri, Oct 16 - Sat, Oct 31
YVR
Vancouver
STL
St. Louis
CA $380 Roundtrip, found 12 hours ago
CA $380
Roundtrip
found 12 hours ago
Select Air Canada flight, departing Fri, Oct 16 from Vancouver to St. Louis, returning Sat, Oct 31, priced at CA $380 found 12 hours ago
Alaska Airlines
Thu, Sep 24 - Wed, Sep 30
YYC
Calgary
STL
St. Louis
CA $719 Roundtrip, found 21 hours ago
CA $719
Roundtrip
found 21 hours ago
Select Alaska Airlines flight, departing Thu, Sep 24 from Calgary to St. Louis, returning Wed, Sep 30, priced at CA $719 found 21 hours ago

Frequently asked questions

What is the name of Defiance's airport?
Book a flight to Defiance and you'll be touching down at Lambert-St. Louis Intl. Airport (STL).
How far is Lambert Field from central Defiance?
Long commutes don't have to be stressful if you consider your options ahead of time. Downtown Defiance is 40 kilometres from STL, so it's smart to know how you'll get into the city before you touchdown.
What airport is best to fly into Defiance?
STL is the main airport in Defiance. Before you head there, it's a wise idea to research a thing or two about it. It sits about 40 kilometres from the downtown area.
How many airlines fly to Defiance?
There are 12 air carriers that jet into Defiance from 61 airports around the world.
Which airlines fly to Defiance?
United Airlines and American Airlines fly often into Defiance. Catching a United Airlines flight from Chicago is one of the most popular ways to get there.
How many nonstop flights are there to Defiance?
Organizing an unforgettable Defiance escape is a walk in the park when there are 1,206 nonstop flights each week to choose from.
Where are the most popular flights to Defiance departing from?
Travellers frequently set off from Chicago, Dallas and New York airports when going to Defiance.
How long is the flight to Defiance Airport?
Where you depart from determines how much of the in-flight entertainment you'll get to enjoy. From Chicago to Defiance, the average flight time is 1 hour and 22 minutes. From Dallas it's more like 1 hour and 43 minutes, and from New York it's 3 hours and 1 minute.
How to book the cheapest flight to Defiance?
We've all come across those jet-setters who somehow manage to nab extremely cheap plane tickets wherever they go. Want to know how to do it for your Defiance vacation? Don't wait until the last minute to lock in your flight. Also, look around online and compare your options. If your destination has several airports, you may be able to pick up an excellent deal by flying into a less busy terminal. Finally, another simple way to save some cash is be ready to book at a moment's notice. If you see a fantastic bargain, don't hold off — grab it while you've got the chance.
Do you have any tips for my flight to Defiance?
Depending on where you're coming from, your flight to Defiance could be a piece of cake or it could go on forever. Below are some handy hints that will help you start your next big adventure on a positive note. What to pack in your hand luggage:

  • It's simple — first, put in your passport, official ID, bank cards and daily medications. Next, you'll want some extra in-flight entertainment to help pass the time. A juicy book and a phone crammed with your favourite movies are some wonderful options. If you plan to take a quick snooze, a quality neck pillow and a pair of earplugs will also be useful. Finally, leave some space for a toothbrush and some facial wipes to ensure you hop off the plane feeling fresh as a daisy.

Do not pack the following items in your hand luggage:

  • Leave all your full-sized bottles of shampoo and conditioner in your checked luggage. Any liquids or gels in your carry-on bag larger than 3.4 ounces (100 millilitres) will be confiscated by security. Sharp objects, like your precious Swiss Army knife, and dangerous products which are flammable or explosive, such as flares, chemicals agents and strong acids, are also not allowed.

What to wear on a flight:

  • The aisles of a plane aren't the place for a fashion parade. Wear layers and go for shoes that are flat, enclosed and easy to remove.
  • The result of sustained periods of immobility, deep vein thrombosis (DVT) is a blood clot condition that can affect some passengers during long-haul flights. Reduce the risks by staying hydrated, keeping your feet and legs moving and wearing compression socks or tights.

How to get through airport security fast when flying to Defiance?
Being organized before you get to the airport will make your getaway to Defiance quick and painless. Read through our useful tips and tricks for a speedy journey past security:

  • First things first. Your travel ID and boarding pass will need to be shown to airport security. Keep them within easy reach so you don't hold up the queue.
  • Your jacket, belt, keys and other small items, like your headphones, will be required to go through the X-ray machine. Make your life easier by removing them before your turn arrives.
  • Your electronic gadgets like laptops and phones will also have to go through the machine to be scanned. Don't worry though, you'll be back online before you know it.
  • Remember to remove liquids and gels from your carry-on bag. They usually need to be sent through the X-ray separately. Each item should be in a container no larger than 3.4 ounces (100 millilitres) and everything must fit in a single quart-size (one litre), clear zip-lock bag.
  • Choosing your footwear wisely can save you several minutes. Boots and bulky shoes are often required to be removed and X-rayed separately. Slip-on sneakers usually aren't.
  • Avoid taking prohibited items in your carry-on bag. If you have any sharp or pointed objects, put them in your checked suitcase. They won't be allowed on board.

Book with confidence

Expedia.ca gives you the best tools to secure great deals on flights to Defiance. Use our easy and convenient booking engine to browse nonstop flights and convenient departure points every day of the year. Search airfares from the top airlines to book your perfect flight to Defiance. Whatever your travel needs, you can always rely on Expedia.ca to help you find cheap flights to Defiance.

Using our booking engine is simple - just type in your points of travel and preferred dates and Expedia.ca does the rest! If your travel times are flexible, you can find even better bargains by adjusting your flight dates. Browse connecting flights to increase your chances of finding even lower fares. Thanks to Expedia's Best Price Guarantee, you can book your Defiance flights with full confidence knowing that you've found the best deal online.

Expedia.ca makes the booking process easy and stress-free by offering support along the entire way. Our friendly staff is available 24 hours a day to provide assistance and help you book your ticket. Call us toll-free at 1-888-397-3342 to answer any questions that you may have about your trip to Defiance.

Looking to save even more? Get additional savings by bundling your Defiance flight with a hotel and/or car rental to create a bargain travel package. Early birds can discover terrific savings by booking in advance while last minute travelers can enjoy great last minute deals. With Expedia.ca, there's no shortage of options to save even more on your Defiance trip!

Travel information

Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Destination city name
St. Louis
Roundtrip price
CA $333

Trending flights to Defiance

Prices were available within the past 7 days and start at CA $168 for one-way flights and CA $333 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Oct 20 - Mon, Nov 9
YVR
Vancouver
STL
St. Louis
CA $375 Roundtrip, found 12 hours ago
CA $375
Roundtrip
found 12 hours ago
Select United flight, departing Tue, Oct 20 from Vancouver to St. Louis, returning Mon, Nov 9, priced at CA $375 found 12 hours ago

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