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Top 10 St. Charles hotels and places to stay

Courtyard
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
4.0 star property
9.4 out of 10, Exceptional, (602)
"Lovely, modern hotel. Very comfortable bed, nice room and bathroom. Would definitely stay here again. "
The price is CA $158
CA $184 total
includes taxes & fees
Jun 2 - Jun 3
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Aerial view
Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
7.6 out of 10, Good, (1200)
"We checked out but needed to extend our parking a little so Mayo appointments could be finished….they did this graciously….."
The price is CA $158
CA $182 total
includes taxes & fees
May 30 - May 31
Kahler Inn and Suites - Mayo Clinic Area
Indoor pool
Kahler Grand Hotel
3.0 star property
8.2 out of 10, Very good, (1000)
"There was a renovation ongoing and not fair to answer question about property conditions and facilities."
The price is CA $203
CA $234 total
includes taxes & fees
Jun 9 - Jun 10
Kahler Grand Hotel
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Terrace/patio
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
9.0 out of 10, Wonderful, (548)
"Parking was easy. Very walkable to Mayo."
The price is CA $151
CA $174 total
includes taxes & fees
Jun 9 - Jun 10
Hyatt House Rochester/Mayo Clinic Area
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
7.8 out of 10, Good, (1000)
"Good place to stay "
The price is CA $115
CA $133 total
includes taxes & fees
May 31 - Jun 1
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Exterior
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 star property
8.8 out of 10, Excellent, (543)
"Great service"
The price is CA $162
CA $191 total
includes taxes & fees
Jun 28 - Jun 29
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Exterior
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (1000)
"Very clean"
The price is CA $137
CA $157 total
includes taxes & fees
Jun 23 - Jun 24
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
In-room safe, desk, iron/ironing board, free cribs/infant beds
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
8.0 out of 10, Very good, (1000)
"The room was small, but okay for a single person. The bed was okay, it was clean. Loved the bench above the air conditioner/heater. The breakfast was standard cold and hot items, but not much for sitting, so you may need to eat in your room. The down fall was I could hear a TV going in the next room and in the other room, hear a phone alarm going off."
The price is CA $92
CA $105 total
includes taxes & fees
Jun 2 - Jun 3
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Terrace/patio
Hampton Inn Rochester-South
2.5 star property
9.0 out of 10, Wonderful, (1001)
"I have a wonderful time is staying there thank you so much team "
The price is CA $115
CA $133 total
includes taxes & fees
Jun 23 - Jun 24
Hampton Inn Rochester-South
Blackout drapes, soundproofing, iron/ironing board, free WiFi
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
8.2 out of 10, Very good, (392)
"I am making another reservation this coming week. THIS hotel i nice. Bedding is great."
The price is CA $121
CA $139 total
includes taxes & fees
Jun 9 - Jun 10
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
BBQ/picnic area
Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
9.4 out of 10, Exceptional, (86)
"Wonderful rooms and accommodations. "
The price is CA $161
CA $185 total
includes taxes & fees
Jun 6 - Jun 7
Residence Inn by Marriott Rochester Mayo Clinic Area South
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
9.0 out of 10, Wonderful, (618)
"Nice place to stay!"
The price is CA $170
CA $196 total
includes taxes & fees
May 30 - May 31
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Free daily buffet breakfast
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
9.8 out of 10, Exceptional, (281)
"This is my secound time and it will be my hotel for many years to come on my visits to mayo clinic. Love the staff, loved the cleanliness and the transportation."
The price is CA $161
CA $185 total
includes taxes & fees
Jun 14 - Jun 15
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
2.5 star property
8.8 out of 10, Excellent, (609)
"It was fine The staff was friendly and helpful. "
The price is CA $140
CA $161 total
includes taxes & fees
Jun 1 - Jun 2
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
9.6 out of 10, Exceptional, (624)
"The property was very clean and staff was friendly. The rooms were large and clean. Perfect kitchenette if staying for longer trips (ie Mayo Clinic). The beds were on the firm side but not uncomfortable. Parking was a bit tight and limited for our large vehicle however it was preferable to the parking garages offered closer to the hospital. Lots of food in walking distance (BWW and Panera). The Hot Chip Burger Bar across the street had a great burger. We will likely stay here again for future...
The price is CA $173
CA $199 total
includes taxes & fees
Jun 9 - Jun 10
Home2 Suites by Hilton Rochester Mayo Clinic Area
Lobby
Hilton Rochester Mayo Clinic Area
3.5 star property
9.6 out of 10, Exceptional, (338)
"The hotel was very Beautiful and very clean. It was beautifully decorated. The staff were all super helpful and courteous. The only complaint I have is that the bed was hard as a rock. We had a very nice room with a king bed and beautiful views, but that bed was hard as a rock. That’s the only thing that could use an Upgrade. The room and the bathroom were extremely clean. I would definitely stay there again with a softer bed. And also housekeeping put a fresh sheet on there had a hole in it on...
The price is CA $242
CA $279 total
includes taxes & fees
Jun 7 - Jun 8
Hilton Rochester Mayo Clinic Area
Indoor spa tub
Quality Inn near Medical Center
2.5 star property
8.0 out of 10, Very good, (498)
"Staff was great. Older property but very clean. Good breakfast. Will be back!"
The price is CA $92
CA $105 total
includes taxes & fees
Jun 9 - Jun 10
Quality Inn near Medical Center
Desk, iron/ironing board, free WiFi, bed sheets
Brentwood Inn & Suites
2.5 star property
8.6 out of 10, Excellent, (1000)
"Close to Mayo Clinic at a reasonable price"
The price is CA $162
CA $187 total
includes taxes & fees
Jun 7 - Jun 8
Brentwood Inn & Suites
Lunch and dinner served, American cuisine
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
8.2 out of 10, Very good, (1003)
"Staff very helpful and room very clean and comfortable "
The price is CA $168
CA $193 total
includes taxes & fees
May 30 - May 31
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Premium bedding, desk, iron/ironing board, free cribs/infant beds
Aspen Select
3.5 star property
8.6 out of 10, Excellent, (1000)
"Nice quiet well managed property "
The price is CA $170
CA $216 total
includes taxes & fees
May 30 - May 31
Aspen Select
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where is the best place to stay in St. Charles?

Kahler Grand Hotel, located 20.6 mi (33.1 km) from the heart of St. Charles, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel and Kahler Inn and Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in St. Charles.

What's the top vacation rental in St. Charles?

Century Cottage-PERFECT for Mayo & downtown visitors!: This vacation home rental outside of St. Charles is located in the city center and has a patio, a garden, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Make the most of the selection of games in this rental home to help you unwind. See all vacation rentals in St. Charles.

If I need to cancel my hotel reservation in St. Charles, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in St. Charles.

Where can I learn more about changing or cancelling my trip to St. Charles?

To access more information about updating your trip to St. Charles or cancelling it, go to https://www.expedia.com/service/.

Where is the best hotel to stay near Whitewater State Park?

White Valley Motel is one of the top choices for your stay based on our traveler data, and this property offers free parking and free WiFi. You'll find it 6.4 mi (10.3 km) from Whitewater State Park. Other good choices around the area include Kahler Inn and Suites - Mayo Clinic Area and La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S.

What are some hotels with pools in St. Charles?

Kahler Inn and Suites - Mayo Clinic Area: 3.5-star hotel steps from Mayo Clinic. Offers a snack bar, an indoor pool, and free WiFi. Even Hotel Rochester - Mayo Clinic Area and La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S are a couple of other choices with an onsite pool. View all hotels with pools in St. Charles.

What's the best hotel for staying near Rochester International Airport (RST)?

AmericInn by Wyndham Rochester Airport is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 0.6 mi (1 km) from Rochester Intl. Airport. Other choices near the airport include La Quinta Inn & Suites by Wyndham Rochester and Comfort Suites.

What's it like staying in St. Charles?

Visitors can enjoy all that St. Charles has to offer including its parks. This city also attracts tourists with its welcoming locals. In St. Charles, there are 2 hotels and other accommodations to choose from. Find out more about St. Charles.

What is there to see in St. Charles?

The picturesque setting of Whitewater State Park and Whitewater River exemplify the area's natural beauty. You'll also find Regional Sports Center and National Volleyball Center in the area. Check out what more to see and do in Expedia's St. Charles guide.

What's the seasonal weather like in St. Charles?

The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 22°F. The snowiest months in St. Charles are January, March, February, and October, with each month seeing an average of 7 inches of snowfall.

Recent Reviews in St. Charles
Expedia verified reviews