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Cheap Hotels in Southeast Missouri

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane Sikeston MO

4 hours drive from Johnson's Shut-ins State Park

Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

8.4/10 Very good! (794 reviews)

"Stay was good, clean room"

Reviewed on Jun 30, 2026

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

4 hours drive from Johnson's Shut-ins State Park

Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...

9/10 Wonderful! (1,003 reviews)

"Great service"

Reviewed on Jul 2, 2026

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

2 hours drive from Johnson's Shut-ins State Park

Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...

8/10 Very good! (1,002 reviews)

"Clean room only soap bar for toiletries. Parking was plentiful."

Reviewed on Jul 2, 2026

See all 676 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.