Book The Best Hotels in St. Charles, MN for 2026 from CA $87 - Fully Refundable Options

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Our top choices for St. Charles hotels

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large mirror.

An indoor swimming pool with clear water, a lifeguard on duty sign, and a seating area with chairs and tables.

A hotel room with a sofa, a small table, a TV, a microwave, and a door.

A hotel lobby with seating, a fireplace, a clock, and a reception area.

1. AmericInn by Wyndham Winona

Winona

SANDRA

CA $169

CA $189 total

includes taxes & fees

Sep 6 - Sep 7

A modern hotel lobby with a reception desk, seating area, and a kitchenette.

A hotel with a covered entrance, multiple floors, and a parking lot.

A hotel room with a large bed, a desk, a chair, and a kitchenette.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

2. Spark by Hilton Rochester South

Rochester

Helena

CA $107

CA $123 total

includes taxes & fees

Sep 5 - Sep 6

A hotel room with two beds, a large landscape painting above the headboard, a bedside table with a phone, and a blue patterned rug.

A reception area with a counter, a clock, a desk with a computer, and a framed picture on the wall.

A modern room with two sofas, a coffee table, and large windows with curtains.

A breakfast area with a coffee station, a refrigerator, and a dining table with chairs.

3. Days Inn by Wyndham Winona

Winona

LeAndre

CA $95

CA $106 total

includes taxes & fees

Sep 6 - Sep 7

An outdoor seating area with wicker chairs and tables, surrounded by vibrant flowers and a red umbrella.

A rustic bar area with wooden beams, a wooden counter, and sacks of grain.

A bedroom with a large bed, a bathtub, a wooden rocking chair, and a desk with a lamp.

A spacious living area with a high ceiling, wooden beams, a blue armchair, a sofa, and a glass coffee table.

4. Stone Mill Hotel & Suites

Lanesboro

Jenifer

CA $146

CA $157 total

includes taxes & fees

Sep 1 - Sep 2

A multi-story building with a balcony, surrounded by various potted plants and flowers.

A porch with a variety of potted plants and flowers, a sign reading "OFFICE Welcome to Green Gables," and a door with a green doorbell.

A bedroom with a four-poster bed, a sitting area with a sofa, a small table with a vase, and a bathtub.

A bedroom with a four-poster bed, a sofa, a desk, and a fireplace.

5. Green Gables Inn

Lanesboro

MaryPat

CA $160

CA $172 total

includes taxes & fees

Aug 31 - Sep 1

A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.

6. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

Deborah

CA $115

CA $133 total

includes taxes & fees

Sep 30 - Oct 1

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

A hotel room with two beds, a desk, a chair, and a mirror.

An indoor swimming pool with a slide, seating area, and a large frog statue.

A bar with wooden stools and a neon sign.

7. AmericInn by Wyndham Rochester Near Mayo Clinic

Rochester

Cathy

CA $108

CA $124 total

includes taxes & fees

Sep 13 - Sep 14

A La Quinta Inn & Suites hotel with a well-lit entrance, a parking area, and a clear view of the building's facade.

A hotel reception area with wooden reception desks, a cityscape mural on the wall, and a check-in counter with a bookshelf.

A buffet counter with a variety of food items, a coffee station, and a beverage dispenser.

An indoor swimming pool with a slide, seating areas, and a lifeguard station.

8. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Rochester

Jason

CA $104

CA $119 total

includes taxes & fees

Sep 13 - Sep 14

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

9. Hampton Inn Rochester-South

Rochester

Lynne

CA $141

CA $163 total

includes taxes & fees

Sep 7 - Sep 8

A two-story house with a porch and a covered entryway.

A bedroom with a wooden wardrobe, a bedside table with a lamp, and a bed with white bedding and a red pillow.

A porch with a white door labeled "WENNESON" and a welcome wreath.

A hallway with a wooden floor, a chandelier, a bust sculpture, and a door leading to another room.

10. The Wen Inn formerly Andor Wenneson

Peterson

Ruth

CA $157

CA $171 total

includes taxes & fees

Sep 3 - Sep 4

A modern hotel lobby with a reception desk, seating area, and a dining space.

A modern hotel room with a wooden desk, orange chair, dark sofa, and a small table.

A Holiday Inn Express building with a stone facade and illuminated signage.

A hotel room with a bed, desk, chair, and a bathroom.

11. Holiday Inn Express Rochester South - Mayo Area by IHG

Rochester

Stephanie

CA $142

CA $163 total

includes taxes & fees

Sep 27 - Sep 28

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

A compact laundry area with a washing machine, dryer, and a water fountain.

12. Econo Lodge Mayo Clinic Area

Rochester

Markus

CA $95

CA $110 total

includes taxes & fees

Sep 20 - Sep 21

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A compact kitchen with a microwave, refrigerator, and coffee maker. A small bar stool is near the counter.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

13. Quality Inn & Suites Mayo Clinic Area

Rochester

Cassandra

CA $106

CA $124 total

includes taxes & fees

Sep 5 - Sep 6

A hotel room with two beds, a desk, a chair, and a lamp.

A swimming pool with a capacity sign, a lifeguard warning sign, and a spa rules sign.

A lobby with a checkered floor, two blue armchairs, a table with a lamp, and a 'WELCOME' sign.

A hotel lobby with a dining area, a fireplace, and a television displaying a map.

14. Country Trails Inn & Suites

Preston

Robert

CA $176

CA $194 total

includes taxes & fees

Aug 31 - Sep 1

A modern lobby with a reception desk, a green sofa, and a black spherical table.

An outdoor dining area with wooden beams, tables, and chairs.

A modern hotel with a prominent 'Hotel Indigo' sign, a 'Crave Drink' restaurant, and a well-lit facade.

A modern bar area with a central island, bar stools, and hanging spherical light fixtures.

15. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

Kyle

CA $143

CA $165 total

includes taxes & fees

Sep 4 - Sep 5

A hotel pool area with multiple lounge chairs, a pool, and a second-floor balcony with windows.

A hotel room with a large bed, a separate bathroom with a bathtub, and a small bedside table with a lamp.

A brick building with a sign reading "Riverport Inn & Suites" and two flags.

A spacious lobby with a stone fireplace, leather seating, a staircase with glass railings, and a view of the outside through large windows.

16. Express Suites Riverport Inn & Suites

Winona

Carol

CA $167

CA $186 total

includes taxes & fees

Aug 31 - Sep 1

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

17. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park

Jon

CA $155

CA $179 total

includes taxes & fees

Sep 18 - Sep 19

A hotel room with two beds, a desk with a chair, a TV, and a large waterfall painting on the wall.

An outdoor patio with a table and chairs, a red umbrella, and a view of trees and a sunset.

A reception area with a modern design, featuring a check-in counter, a door, and a small seating area with red stools.

A breakfast area with a wooden wall, a clock, and a coffee machine.

18. Super 8 by Wyndham Winona MN

Winona

Noel

CA $89

CA $101 total

includes taxes & fees

Sep 20 - Sep 21

A modern dining area with high tables, chairs, and pendant lighting.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a parking lot in front.

A reception desk with a large digital screen displaying a cityscape and the word "happy."

A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.

19. Hampton Inn & Suites Rochester-North

Rochester

Albert

CA $136

CA $156 total

includes taxes & fees

Sep 5 - Sep 6

A hotel room with a large bed, a desk with a chair, a television, and a view of the outdoors through a door.

A compact hotel room with a kitchenette, a leather chair, and a view of the balcony.

A hotel room with a large bed, a desk, a chair, and a TV.

A breakfast corner with a counter, seating area, and a red partition.

20. Baymont by Wyndham Rochester Mayo Clinic Area

Rochester

Bobbi

CA $83

CA $95 total

includes taxes & fees

Sep 6 - Sep 7

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St. Charles awaits: its natural setting and more!

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Top St. Charles Hotel Reviews

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Great property. Free breakfast, happy hour a few days, huge lobby and patio are. Convenient shuttle to Mayo Clinic. Fully stocked kitchens, coffee, and dishwasher. Laundry on site if needed."

Aspen Select

10/10 Excellent

"Construction in the area is crazy, but if you are looking for a good price near the Mayo Clinic then this is your hotel. The sister property was almost 3x the price. Still has good access during Mayo construction. Directly across from Saint Mary’s"

Green Gables Inn

10/10 Excellent

"Wonderful property. Comfortable beds. Gorgeous grounds on the river. Brian & Tracy were very welcoming"

Kahler Grand Hotel

8/10 Good

"Toilets were too low for seniors….put higher toilets in. It is ridicules to have to sit almost of the floor, especially in room 562!!! Otherwise every thing was wonderful!!"

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"This property has a good location and since it’s newer, that’s an added bonus. They have a complimentary, elevated breakfast which is great."

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good

"Check out was very confusing. It took about a half hour and I am still not sure if the billing was correct. Food was fine."

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"The hotel was nice and clean, staff were very pleasant, breakfast was a big tasty buffet. The only complaint was the parking garage was very little and barely fit my mid size SUV because of how low the ceiling was, but there is another garage next to the hotel that was actually cheaper. Also, being on the side where all the construction was going on, but I get it they had to start super early because of the heat. Most importantly though it was with walking distance from all of my Mayo appts and several restaurants."

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"This is my first time staying at Hotel Indigo. The staff was amazing. I had to keep adding nights and they were so accommodating. The room was just right. It was clean , well stocked and easy access to the Mayo Clinic. I really liked the front desk people. Super friendly and helpful. Love the attached restaurant!"

More cheap stays in St. Charles

Super 8 by Wyndham Rochester Mayo Clinic Area

106 SE 21st Street Rochester MN

CA $76

CA $87 total

Sep 6 - Sep 7

includes taxes & fees

Super 8 by Wyndham Winona MN

1025 Sugar Loaf Rd Winona MN

CA $89

CA $101 total

Sep 20 - Sep 21

includes taxes & fees

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

CA $105

CA $121 total

Aug 31 - Sep 1

includes taxes & fees

8/10 Very good! (1,007 reviews)

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN

CA $137

CA $158 total

Sep 20 - Sep 21

includes taxes & fees

Hampton Inn Rochester-South

1755 S Broadway Rochester MN

CA $141

CA $163 total

Sep 7 - Sep 8

includes taxes & fees

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

CA $174

CA $200 total

Sep 3 - Sep 4

includes taxes & fees

8.8/10 Excellent! (1,002 reviews)

Hotels in St. Charles with star rating

Frequently asked questions

What are the best hotels in St Charles that travellers recommend?

For a highly recommended hotel in St Charles, the White Valley Motel is an excellent option.Guests frequently mention that the rooms are comfortable and clean, and the staff are friendly. The motel offers air conditioning and free self-parking, adding to the convenience for travellers.

What are the top pet-friendly hotels in St Charles?

For a popular pet-friendly hotel in St Charles, the White Valley Motel is a great option.The White Valley Motel welcomes pets and offers convenient amenities such as free WiFi and complimentary toiletries. Guests often mention the comfortable and clean rooms, as well as the friendly staff. Free self-parking is also available, and the Whitewater River is approximately 9.6 kilometres away. See more pet-friendly hotels in St Charles

What are the best budget hotels in St Charles?

In St Charles, a top budget-friendly option is the White Valley Motel.This motel offers comfortable and clean rooms, as frequently mentioned by guests, along with friendly staff. Key amenities include free WiFi, complimentary toiletries, free self-parking, and air conditioning for a pleasant stay. It is also conveniently located just 9.6 km from the Whitewater River, making it an ideal base for exploring the area. View all budget hotels in St Charles

When is the best time to go to St Charles?

The best time to go to St. Charles, Minnesota, is during the summer months, from June to August, when the weather is warm and sunny, great for outdoor activities.During this period, the average daily temperatures range from 20°C to 28°C, making it comfortable for exploring the area's natural beauty. You'll find the Root River ideal for kayaking, canoeing, and fishing, with many local outfitters available for equipment hire. The numerous walking and cycling trails, such as the Root River State Trail, are also at their best, offering scenic views of the countryside.Couples looking for an active getaway will particularly enjoy the summer. The warm weather means you can spend your days cycling along the trails, perhaps stopping at small towns along the route, or enjoying a leisurely paddle on the river. Evenings can be spent at local restaurants, many of which offer outdoor seating to enjoy the pleasant temperatures.Families will also find summer an excellent time to visit. The mild weather allows for plenty of outdoor play, whether it's exploring Whitewater State Park, known for its trout fishing and hiking trails, or enjoying picnics by the river.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in St. Charles.

How much is the nightly rate at a St. Charles hotel?

Prices for hotels in St. Charles often vary, but you can find a great deal from CA $87 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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Find hotels in St. Charles, MN from CA $87

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in St. Charles

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for St. Charles hotels

1. AmericInn by Wyndham Winona

2. Spark by Hilton Rochester South

3. Days Inn by Wyndham Winona

4. Stone Mill Hotel & Suites

5. Green Gables Inn

6. Comfort Inn & Suites Rochester South Mayo Clinic

7. AmericInn by Wyndham Rochester Near Mayo Clinic

8. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

9. Hampton Inn Rochester-South

10. The Wen Inn formerly Andor Wenneson

11. Holiday Inn Express Rochester South - Mayo Area by IHG

12. Econo Lodge Mayo Clinic Area

13. Quality Inn & Suites Mayo Clinic Area

14. Country Trails Inn & Suites

15. Hotel Indigo Rochester – Mayo Clinic Area by IHG

16. Express Suites Riverport Inn & Suites

17. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

18. Super 8 by Wyndham Winona MN

19. Hampton Inn & Suites Rochester-North

20. Baymont by Wyndham Rochester Mayo Clinic Area

Learn more about St. Charles

Top St. Charles Hotel Reviews

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Aspen Select

Green Gables Inn

Kahler Grand Hotel

Hyatt House Rochester/Mayo Clinic Area

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kahler Inn and Suites - Mayo Clinic Area

Hotel Indigo Rochester – Mayo Clinic Area by IHG

More cheap stays in St. Charles

Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Winona MN

Med City Inn & Suites - Mayo Clinic Area

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Hampton Inn Rochester-South

Brentwood Inn & Suites

Hotels in St. Charles with star rating

Frequently asked questions

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