Book The Best Hotels in St. Charles, MN for 2026 from CA $83 - Fully Refundable Options

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Our top choices for St. Charles hotels

A modern hotel lobby with a reception desk, seating area, and a kitchenette.

A small, well-organized pantry with shelves stocked with snacks and beverages.

A hotel room with a large bed, a desk, a chair, and a kitchenette.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

1. Spark by Hilton Rochester South

Rochester

Stanton

CA $108

CA $124 total

includes taxes & fees

Oct 26 - Oct 27

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

A compact laundry area with a washing machine, dryer, and a water fountain.

A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

2. Econo Lodge Mayo Clinic Area

Rochester

Ashley

CA $95

CA $110 total

includes taxes & fees

Nov 8 - Nov 9

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

A hotel room with two beds, a desk, a chair, and a mirror.

A bar with wooden stools and a neon sign.

An indoor swimming pool with a slide, seating area, and a large frog statue.

3. AmericInn by Wyndham Rochester Near Mayo Clinic

Rochester

blake

CA $104

CA $120 total

includes taxes & fees

Oct 17 - Oct 18

A two-story house with a porch and a covered entryway.

A hallway with a wooden floor, a chandelier, a bust sculpture, and a door leading to another room.

A bedroom with a wooden wardrobe, a bedside table with a lamp, and a bed with white bedding and a red pillow.

A room with two patterned sofas, a small table with a lamp, and a window with curtains.

4. The Wen Inn formerly Andor Wenneson

Peterson

Jessica

CA $161

CA $176 total

includes taxes & fees

Oct 20 - Oct 21

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

5. Quality Inn & Suites Mayo Clinic Area

Rochester

Jessica

CA $105

CA $123 total

includes taxes & fees

Nov 6 - Nov 7

An outdoor seating area with wicker chairs and tables, surrounded by vibrant flowers and a red umbrella.

A cozy living room with a fireplace, a staircase, and a dining area.

A rustic bar area with wooden beams, a wooden counter, and sacks of grain.

A bedroom with a large bed, a bathtub, a wooden rocking chair, and a desk with a lamp.

6. Stone Mill Hotel & Suites

Lanesboro

Jenifer

CA $149

CA $160 total

includes taxes & fees

Oct 18 - Oct 19

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

A modern bar area with seating and a counter.

A modern indoor pool area with lounge chairs and a pool.

7. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

Elsie

CA $169

CA $194 total

includes taxes & fees

Oct 23 - Oct 24

A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.

A laundry area with two Whirlpool washers and a dryer, a wooden shelf above, and a white ceiling.

A gym with treadmills, elliptical machines, and a stationary bike.

A modern living room with a sofa, two armchairs, a coffee table, and a large window offering a view of the outdoors.

8. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

Phil

CA $116

CA $134 total

includes taxes & fees

Nov 12 - Nov 13

A multi-story building with a balcony, surrounded by various potted plants and flowers.

A bedroom with a four-poster bed, a sofa, a desk, and a fireplace.

A bedroom with a four-poster bed, a sitting area with a sofa, a small table with a vase, and a bathtub.

A porch with a variety of potted plants and flowers, a sign reading "OFFICE Welcome to Green Gables," and a door with a green doorbell.

9. Green Gables Inn

Lanesboro

Gary

CA $143

CA $154 total

includes taxes & fees

Oct 19 - Oct 20

A hotel room with two beds, a large landscape painting above the headboard, a bedside table with a phone, and a blue patterned rug.

A gym with treadmills, an elliptical, and a stationary bike.

A reception area with a counter, a clock, a desk with a computer, and a framed picture on the wall.

A breakfast area with a coffee station, a refrigerator, and a dining table with chairs.

10. Days Inn by Wyndham Winona

Winona

William

CA $93

CA $104 total

includes taxes & fees

Nov 8 - Nov 9

A spacious outdoor dining area with modern furniture and large windows offering views of the city.

An outdoor dining area with wooden beams, tables, and chairs.

A modern interior with a wooden ceiling, a large black shelving unit, and a refrigerator stocked with beverages.

A modern hotel room with a large bed, a sofa, a small table, a desk, and a wardrobe.

11. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

Hernan

CA $147

CA $169 total

includes taxes & fees

Nov 13 - Nov 14

A modern hotel lobby with a reception desk, seating area, and a dining space.

A Holiday Inn Express building with a stone facade and illuminated signage.

A modern breakfast area with a counter displaying various food items, a water dispenser, and a sign indicating a bakery section.

A hotel room with a bed, desk, chair, and a bathroom.

12. Holiday Inn Express Rochester South - Mayo Area by IHG

Rochester

Melissa

CA $138

CA $159 total

includes taxes & fees

Nov 12 - Nov 13

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

A restaurant interior with wooden tables, chairs, and a stone wall.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

13. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest

Christine

CA $162

CA $187 total

includes taxes & fees

Oct 17 - Oct 18

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large mirror.

A hotel lobby with seating, a fireplace, a clock, and a reception area.

A hotel room with a sofa, a small table, a TV, a microwave, and a door.

An indoor swimming pool with clear water, a lifeguard on duty sign, and a seating area with chairs and tables.

14. AmericInn by Wyndham Winona

Winona

Jonathan

CA $191

CA $213 total

includes taxes & fees

Oct 18 - Oct 19

A modern indoor patio with a fire feature, seating, and large windows.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

15. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

James

CA $163

CA $190 total

includes taxes & fees

Oct 16 - Oct 17

A La Quinta Inn & Suites hotel with a well-lit entrance, a parking area, and a clear view of the building's facade.

A buffet counter with a variety of food items, a coffee station, and a beverage dispenser.

An indoor swimming pool with a slide, seating areas, and a lifeguard station.

A hotel reception area with wooden reception desks, a cityscape mural on the wall, and a check-in counter with a bookshelf.

16. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Rochester

Alvaro

CA $103

CA $118 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with a dark countertop, black cabinets, a microwave, and a refrigerator. There are two pendant lights above the counter.

A hotel gym with treadmills, elliptical machines, and free weights.

A hotel lobby with a reception desk, seating area, and a large window.

A hotel room with a large round table, two sofas, a TV, and a bed.

17. Candlewood Suites Rochester Mayo Clinic Area by IHG

Rochester

Kevin

CA $166

CA $191 total

includes taxes & fees

Oct 16 - Oct 17

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

18. Hampton Inn Rochester-South

Rochester

dennis

CA $156

CA $180 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a reception desk, seating area, and a bar.

A hotel room with two beds, a desk, a TV, and a large window with curtains.

A multi-story hotel with a grey and orange facade, a covered entrance, and a parking lot with marked spaces.

A front-loading white washer and dryer in a laundry room with a window and a door.

19. Super 8 by Wyndham Rochester Mayo Clinic Area

Rochester

Rick

CA $73

CA $83 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel lobby with multiple seating areas, including a central dining table with chairs, a bar area, and a seating section with cushioned chairs.

A hotel reception desk with a modern design, a clock, and a digital screen.

A modern conference room with a long table, multiple chairs, and a wooden partition.

A modern hotel room with a large bed, two bedside tables, and built-in lighting.

20. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kutzky Park

Jackie

CA $156

CA $179 total

includes taxes & fees

Oct 17 - Oct 18

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Top St. Charles Hotel Reviews

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

10/10 Excellent

"Property seems quite new and fresh. Very comfortable room, welcoming staff, and a breakfast that is definitely a cut above most hotel "breakfast included" offerings. Would definitely stay again."

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"Nice place"

Kahler Grand Hotel

8/10 Good

"Got locked in the pool area and had to walk down 11 flights of steps."

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good

"Hallways had overwhelming floral odor. What are they trying to cover up? Went to leave key and check out. Woman at desk was on a long phone call. Couldn’t give me eye contact and multi task. Disappointed for the price."

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Muy buena atención"

Express Suites Riverport Inn & Suites

10/10 Excellent

"Clean rooms, comfortable beds"

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good

"Killed a spider in our room"

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Close to the Mayo Clinic (easy walking distance), and easy to park"

The Plaza Hotel & Suites Winona

10/10 Excellent

"The property was very nice and clean. The location was great and met our needs. The staff was very nice and helpful."

More cheap stays in St. Charles

Super 8 by Wyndham Winona MN

1025 Sugar Loaf Rd Winona MN

CA $80

CA $91 total

Nov 8 - Nov 9

includes taxes & fees

7.6/10 Good! (1,004 reviews)

Birch Hill Suite Rochester – Med City

3595 Commercial Drive SW Rochester MN

CA $83

CA $95 total

Oct 15 - Oct 16

includes taxes & fees

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

CA $108

CA $124 total

Oct 20 - Oct 21

includes taxes & fees

Comfort Inn & Suites Rochester South Mayo Clinic

7320 Airport View Dr Sw Rochester MN

CA $116

CA $134 total

Nov 12 - Nov 13

includes taxes & fees

Holiday Inn Express Rochester South - Mayo Area by IHG

4141 Maine Avenue SE Rochester MN

CA $138

CA $159 total

Nov 12 - Nov 13

includes taxes & fees

8.8/10 Excellent! (1,000 reviews)

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

CA $178

CA $205 total

Nov 7 - Nov 8

includes taxes & fees

Hotels in St. Charles with star rating

Frequently asked questions

What are the best hotels in St Charles that travellers recommend?

For a highly recommended hotel in St Charles, the White Valley Motel is an excellent option.Guests frequently mention that the rooms are comfortable and clean, and the staff are friendly. The motel offers air conditioning and free self-parking, adding to the convenience for travellers.

What are the top pet-friendly hotels in St Charles?

For a popular pet-friendly hotel in St Charles, the White Valley Motel is a great option.The White Valley Motel welcomes pets and offers convenient amenities such as free WiFi and complimentary toiletries. Guests often mention the comfortable and clean rooms, as well as the friendly staff. Free self-parking is also available, and the Whitewater River is approximately 9.6 kilometres away. See more pet-friendly hotels in St Charles

What are the best budget hotels in St Charles?

In St Charles, a top budget-friendly option is the White Valley Motel.This motel offers comfortable and clean rooms, as frequently mentioned by guests, along with friendly staff. Key amenities include free WiFi, complimentary toiletries, free self-parking, and air conditioning for a pleasant stay. It is also conveniently located just 9.6 km from the Whitewater River, making it an ideal base for exploring the area. View all budget hotels in St Charles

When is the best time to go to St Charles?

The best time to go to St. Charles, Minnesota, is during the summer months, from June to August, when the weather is warm and sunny, great for outdoor activities.During this period, the average daily temperatures range from 20°C to 28°C, making it comfortable for exploring the area's natural beauty. You'll find the Root River ideal for kayaking, canoeing, and fishing, with many local outfitters available for equipment hire. The numerous walking and cycling trails, such as the Root River State Trail, are also at their best, offering scenic views of the countryside.Couples looking for an active getaway will particularly enjoy the summer. The warm weather means you can spend your days cycling along the trails, perhaps stopping at small towns along the route, or enjoying a leisurely paddle on the river. Evenings can be spent at local restaurants, many of which offer outdoor seating to enjoy the pleasant temperatures.Families will also find summer an excellent time to visit. The mild weather allows for plenty of outdoor play, whether it's exploring Whitewater State Park, known for its trout fishing and hiking trails, or enjoying picnics by the river.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in St. Charles.

How much is the nightly rate at a St. Charles hotel?

Prices for hotels in St. Charles often vary, but you can find a great deal from CA $83 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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Find hotels in St. Charles, MN from CA $83

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in St. Charles

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for St. Charles hotels

1. Spark by Hilton Rochester South

2. Econo Lodge Mayo Clinic Area

3. AmericInn by Wyndham Rochester Near Mayo Clinic

4. The Wen Inn formerly Andor Wenneson

5. Quality Inn & Suites Mayo Clinic Area

6. Stone Mill Hotel & Suites

7. Hyatt House Rochester/Mayo Clinic Area

8. Comfort Inn & Suites Rochester South Mayo Clinic

9. Green Gables Inn

10. Days Inn by Wyndham Winona

11. Hotel Indigo Rochester – Mayo Clinic Area by IHG

12. Holiday Inn Express Rochester South - Mayo Area by IHG

13. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

14. AmericInn by Wyndham Winona

15. EVEN Hotel Rochester - Mayo Clinic Area by IHG

16. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

17. Candlewood Suites Rochester Mayo Clinic Area by IHG

18. Hampton Inn Rochester-South

19. Super 8 by Wyndham Rochester Mayo Clinic Area

20. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Learn more about St. Charles

Top St. Charles Hotel Reviews

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

AmericInn by Wyndham Rochester Near Mayo Clinic

Kahler Grand Hotel

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Express Suites Riverport Inn & Suites

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Hotel Indigo Rochester – Mayo Clinic Area by IHG

The Plaza Hotel & Suites Winona

More cheap stays in St. Charles

Super 8 by Wyndham Winona MN

Birch Hill Suite Rochester – Med City

Med City Inn & Suites - Mayo Clinic Area

Comfort Inn & Suites Rochester South Mayo Clinic

Holiday Inn Express Rochester South - Mayo Area by IHG

Brentwood Inn & Suites

Hotels in St. Charles with star rating

Frequently asked questions

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