Title: 10 Best Hotels in Santa Lucia, Syracuse for 2025 | Expedia.ca

 

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![The Sanctuary of the Madonna delle Lacrime was erected in memory of the miraculous lacrimation of the effigy depicting the Immaculate Heart of Mary, placed to the bedside of the spouses Lannuso at their humble home in Via degli Orti in Syracuse, in 1953.](https://images.trvl-media.com/place/4912/ebc9711a-483a-4c63-a902-49105c0eea54.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by William Keller

# Hotels in Santa Lucia, Syracuse

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## Go beyond your typical stay in Santa Lucia

Spa

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&amenities=SPA_ON_SITE)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&travelerType=family_friendly)

Farm

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&lodging=AGRITOURISM)

Ocean view

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&amenities=OCEAN_VIEW)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&lodging=APARTMENT)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&amenities=POOL)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&amenities=HOT_TUB)

Villa

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&lodging=VILLA)

Waterpark

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&amenities=WATER_PARK)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&amenities=PETS)

## Check prices for these dates

Tonight

[Nov 19 - Nov 20](https://www.expedia.ca/Hotel-Search?regionId=553248635213209885&startDate=2025-11-19&endDate=2025-11-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 20 - Nov 21](https://www.expedia.ca/Hotel-Search?regionId=553248635213209885&startDate=2025-11-20&endDate=2025-11-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248635213209885&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248635213209885&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Santa Lucia hotels and places to stay

![Suite](https://images.trvl-media.com/lodging/104000000/103530000/103523100/103523090/fbe2e278.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/104000000/103530000/103523100/103523090/c1e0d589.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Triple Room](https://images.trvl-media.com/lodging/104000000/103530000/103523100/103523090/a8563377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite | Bathroom](https://images.trvl-media.com/lodging/104000000/103530000/103523100/103523090/cbd64090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Palazzo Cavalieri

Santa Lucia

9.0/10

Wonderful

(36)

"The location of this hotel is ideal! Directly between the train station and Ortigia. Easy walking to many different restaurants. We very much enjoyed our short stay here and the daily activities hosted by the Hotel. My only iffy thing was the tiles in the bathroom (the shower specifically) seemed a bit older and maybe not as cleanly as it could be, but all in all the room was quite nice. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Lindsay

CA $137

CA $157 total

includes taxes & fees

Dec 9 - Dec 10

[](https://www.expedia.ca/Syracuse-Hotels-Hotel-Cavalieri.h103523090.Hotel-Information)

![Aerial view](https://images.trvl-media.com/lodging/3000000/2980000/2974800/2974756/2465bcdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2980000/2974800/2974756/542cec6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/3000000/2980000/2974800/2974756/3969188e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/3000000/2980000/2974800/2974756/d745213b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grande Albergo Alfeo

Santa Lucia

8.6/10

Excellent

(650)

"The room was nice the location convenient. No view to speak of but centrally located"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Eric

[](https://www.expedia.ca/Syracuse-Hotels-Grande-Albergo-Alfeo.h2974756.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17520000/17519100/17519019/f4662c00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/18000000/17520000/17519100/17519019/3f45e0ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor spa tub](https://images.trvl-media.com/lodging/18000000/17520000/17519100/17519019/f2d141d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Room](https://images.trvl-media.com/lodging/18000000/17520000/17519100/17519019/9785c0f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Caportigia Boutique Hotel

Santa Lucia

9.4/10

Exceptional

(252)

"Fine quality hotel with exceptional service. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Peter

CA $188

CA $224 total

includes taxes & fees

Dec 9 - Dec 10

[](https://www.expedia.ca/Syracuse-Hotels-Caportigia-Boutique-Hotel.h17519019.Hotel-Information)

![Double Room, 1 King Bed, Sea View, Tower | Terrace/patio](https://images.trvl-media.com/lodging/118000000/117120000/117118700/117118661/28a61820.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/118000000/117120000/117118700/117118661/91ad9665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/118000000/117120000/117118700/117118661/f8c72b7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room, Sea View](https://images.trvl-media.com/lodging/118000000/117120000/117118700/117118661/2971ad68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Miranda Boutique

Santa Lucia

CA $274

CA $318 total

includes taxes & fees

Dec 9 - Dec 10

[](https://www.expedia.ca/Syracuse-Hotels-Casa-Miranda-Boutique.h117118661.Hotel-Information)

![Superior Triple Room, Sea View](https://images.trvl-media.com/lodging/106000000/105440000/105439100/105439006/43120257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/106000000/105440000/105439100/105439006/9d342b72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/106000000/105440000/105439100/105439006/25540a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Triple Room, Sea View | Terrace/patio](https://images.trvl-media.com/lodging/106000000/105440000/105439100/105439006/e0cdb4a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fortaleza Charme House

Santa Lucia

10/10

Exceptional

(27)

"Great central location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Craig

CA $205

CA $234 total

includes taxes & fees

Dec 7 - Dec 8

[](https://www.expedia.ca/Syracuse-Hotels-Fortaleza-Charme-House.h105439006.Hotel-Information)

![Double or Twin Room, Balcony, Ocean View](https://images.trvl-media.com/lodging/9000000/8380000/8376700/8376633/08fa3443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/9000000/8380000/8376700/8376633/dc86ccf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room, Balcony, Ocean View](https://images.trvl-media.com/lodging/9000000/8380000/8376700/8376633/4e3736f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room, Balcony, Ocean View](https://images.trvl-media.com/lodging/9000000/8380000/8376700/8376633/da28e6b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### B&B Nike

Santa Lucia

8.8/10

Excellent

(75)

"Clean, good location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Salvatore

[](https://www.expedia.ca/Syracuse-Hotels-BB-Nike.h8376633.Hotel-Information)

![Coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/9000000/8770000/8763800/8763735/a728c4b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/9000000/8770000/8763800/8763735/043cb791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exclusive Apartment | Living area](https://images.trvl-media.com/lodging/9000000/8770000/8763800/8763735/bcb94a08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/9000000/8770000/8763800/8763735/44d2e27e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Nostos rooms & Apartments

Santa Lucia

9.0/10

Wonderful

(273)

"On a main thoroughfare close to Isola di Ortigia. Friendly management and helpful to me."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

CA $99

CA $113 total

includes taxes & fees

Nov 20 - Nov 21

[](https://www.expedia.ca/Syracuse-Hotels-BB-Nostos.h8763735.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/115000000/114690000/114682800/114682713/8646c46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Double Room, City View](https://images.trvl-media.com/lodging/115000000/114690000/114682800/114682713/0927f8d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/115000000/114690000/114682800/114682713/c47ae805.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/115000000/114690000/114682800/114682713/b64fbcce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Nicola Rooms Siracusa

Santa Lucia

9.4/10

Exceptional

(3)

"Stanza molto bella e nuova, ottimi arredi, letto comodo e cuscini comodi, belle tende, bagno bello e pulito, specchio del bagno fantastico con una luce bellissima regolabile a led. Mi sono trovato bene, il personale gentilissimo in particolare la ragazza (Lucia se non ricordo male) super cordiale!"

![Italy](https://a.travel-assets.com/egds/marks/flags/it.svg)

Davide Angelo

CA $127

CA $145 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Syracuse-Hotels-San-Nicola-Rooms-Siracusa.h114682713.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/9000000/8350000/8343300/8343269/328c4e10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Single Room | Terrace/patio](https://images.trvl-media.com/lodging/9000000/8350000/8343300/8343269/53fa88c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily local cuisine breakfast (EUR 1 per person)](https://images.trvl-media.com/lodging/9000000/8350000/8343300/8343269/19f0f8dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/9000000/8350000/8343300/8343269/ee712d79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Le Muse

Santa Lucia

7.4/10

Good

(71)

"The room was great and the staff was exceptionally helpful"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Henry

CA $132

CA $151 total

includes taxes & fees

Nov 21 - Nov 22

[](https://www.expedia.ca/Syracuse-Hotels-Hotel-Le-Muse.h8343269.Hotel-Information)

![Suite, Balcony, Sea View](https://images.trvl-media.com/lodging/3000000/2530000/2522400/2522354/c6129591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2530000/2522400/2522354/3adf887e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room Sea View | Balcony view](https://images.trvl-media.com/lodging/3000000/2530000/2522400/2522354/b3240fc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2530000/2522400/2522354/971ae922.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakkios

Santa Lucia

9.0/10

Wonderful

(62)

"Nice, central, clean, easy to park, quiet during the night, staff was welcoming, nice breakfast with view - excellent choice!"

![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg)

Jon-Kåre

[](https://www.expedia.ca/Syracuse-Hotels-Lakkios.h2522354.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2540000/2539600/2539517/70b64e81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/3000000/2540000/2539600/2539517/07cf493f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/3000000/2540000/2539600/2539517/bf750551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/3000000/2540000/2539600/2539517/00aaef6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel dei Coloniali

Santa Lucia

7.4/10

Good

(166)

"Convenient location for Syracuse town, but in a scruffy area and the whole property is looking tired. Breakfast was adequate. The owner was charming and happy to help."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Rod

CA $88

CA $101 total

includes taxes & fees

Nov 28 - Nov 29

[](https://www.expedia.ca/Syracuse-Hotels-Hotel-Dei-Coloniali.h2539517.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2020000/2010100/2010088/f70e005a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Porch](https://images.trvl-media.com/lodging/3000000/2020000/2010100/2010088/e4ffb628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/3000000/2020000/2010100/2010088/e87add85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2020000/2010100/2010088/327c106f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Piccolo Hotel Casa Mia

Santa Lucia

8.6/10

Excellent

(373)

"The staff is extremely nice and friendly and you feel welcome. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Florentina

[](https://www.expedia.ca/Syracuse-Hotels-Piccolo-Hotel-Casa-Mia.h2010088.Hotel-Information)

![Water view](https://images.trvl-media.com/lodging/36000000/35370000/35360800/35360799/b9e46e77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Sea View](https://images.trvl-media.com/lodging/36000000/35370000/35360800/35360799/aeabb122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, Turkish bath, deep-tissue massages](https://images.trvl-media.com/lodging/36000000/35370000/35360800/35360799/91bc8ac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/36000000/35370000/35360800/35360799/ce81f99e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Re Dionisio Luxury Suites

Santa Lucia

8.8/10

Excellent

(57)

"Spacious room, dated but comfortable."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kenneth

[](https://www.expedia.ca/Syracuse-Hotels-Re-Dionisio-Boutique-Hotel.h35360799.Hotel-Information)

![Triple Room, Housekeeping, City View](https://images.trvl-media.com/lodging/117000000/116080000/116074600/116074546/df13dfdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/117000000/116080000/116074600/116074546/12c7eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double or Twin Room, Housekeeping, City View | View from room](https://images.trvl-media.com/lodging/117000000/116080000/116074600/116074546/4a43860f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Triple Room, Housekeeping, City View](https://images.trvl-media.com/lodging/117000000/116080000/116074600/116074546/d441e12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Agorà

Santa Lucia

10/10

Exceptional

(1)

"Carlo was great. He wanted to help in any way. The room was excellent except for Friday night music and traffic. You want to party it is near there. Would stay there again. Walkable to most places. Good restaurants near by."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bryce

CA $112

CA $128 total

includes taxes & fees

Nov 21 - Nov 22

[](https://www.expedia.ca/Syracuse-Hotels-Agora.h116074546.Hotel-Information)

![View from room](https://images.trvl-media.com/lodging/2000000/1140000/1133800/1133702/95edfb40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/2000000/1140000/1133800/1133702/2ca740bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sport court](https://images.trvl-media.com/lodging/2000000/1140000/1133800/1133702/f98124db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Double Room, Balcony, Sea View](https://images.trvl-media.com/lodging/2000000/1140000/1133800/1133702/f95279e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Mediterraneo

Santa Lucia

7.8/10

Good

(122)

"Very friendly and helpful staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

[](https://www.expedia.ca/Syracuse-Hotels-Hotel-Mediterraneo.h1133702.Hotel-Information)

![Full-size fridge, oven, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/34000000/33450000/33444500/33444412/625bbc70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/34000000/33450000/33444500/33444412/47e24f8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Room | View from room](https://images.trvl-media.com/lodging/34000000/33450000/33444500/33444412/cda7c0a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/34000000/33450000/33444500/33444412/9d0b7c7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gymnasium

Santa Lucia

8.8/10

Excellent

(40)

"Nice kitchen area, centrally located."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Richard

[](https://www.expedia.ca/Syracuse-Hotels-BB-Gymnasium.h33444412.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5030000/5020800/5020784/976bca6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/6000000/5030000/5020800/5020784/bcc4a8df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/6000000/5030000/5020800/5020784/392f1075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Single Room](https://images.trvl-media.com/lodging/6000000/5030000/5020800/5020784/56ed95ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Populus

Santa Lucia

7.8/10

Good

(74)

"Just stay somewhere else, plain and simple."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thomas

CA $111

CA $127 total

includes taxes & fees

Nov 20 - Nov 21

[](https://www.expedia.ca/Syracuse-Hotels-Populus.h5020784.Hotel-Information)

![View from room](https://images.trvl-media.com/lodging/90000000/89290000/89289100/89289079/c137218d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/90000000/89290000/89289100/89289079/3f94f6c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/90000000/89290000/89289100/89289079/ffb2814f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Balcony](https://images.trvl-media.com/lodging/90000000/89290000/89289100/89289079/fdfbfa08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Calafatari B&B

Santa Lucia

10/10

Exceptional

(11)

"We had a lovely stay. Anna was very welcoming. We had a lovely large clean room and a nice modern bathroom. She went all out for breakfast. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carl and Lina

[](https://www.expedia.ca/Syracuse-Hotels-Calafatari.h89289079.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/111000000/110650000/110647700/110647630/d25497d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/111000000/110650000/110647700/110647630/ba6a8506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Triple Room, Balcony, City View](https://images.trvl-media.com/lodging/111000000/110650000/110647700/110647630/3f0d04b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Triple Room, Balcony, City View](https://images.trvl-media.com/lodging/111000000/110650000/110647700/110647630/83e23650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AmaCasa Siracusa

Santa Lucia

10/10

Exceptional

(1)

"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"

![Italy](https://a.travel-assets.com/egds/marks/flags/it.svg)

Alessandro

CA $124

CA $141 total

includes taxes & fees

Nov 20 - Nov 21

[](https://www.expedia.ca/Syracuse-Hotels-AmaCasa-Siracusa.h110647630.Hotel-Information)

![Double Room](https://images.trvl-media.com/lodging/15000000/14740000/14739300/14739278/8803eb09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Triple Room](https://images.trvl-media.com/lodging/15000000/14740000/14739300/14739278/4a9342dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/15000000/14740000/14739300/14739278/363b82ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, free toiletries, hair dryer, bidet](https://images.trvl-media.com/lodging/15000000/14740000/14739300/14739278/d67fb17b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### B&B Siracusa

Santa Lucia

9.0/10

Wonderful

(59)

"Good location, very modern clean accommodation."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Malcolm

CA $101

CA $116 total

includes taxes & fees

Nov 20 - Nov 21

[](https://www.expedia.ca/Syracuse-Hotels-BB-Siracusa.h14739278.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-03&endDate=2025-12-04&regionId=553248635213209885&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

-   Ortigia
-   Tiche
-   Neapolis
-   Grottasanta
-   Acradina

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87667-Temple-Of-Apollo.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Temple of Apollo showing heritage elements and building ruins](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87666-Temple-Of-Apollo.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Temple of Apollo featuring street scenes and heritage elements](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87663-Temple-Of-Apollo.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Temple of Apollo which includes building ruins and heritage elements](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87670-Temple-Of-Apollo.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Temple of Apollo featuring a ruin, street scenes and heritage elements](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87673-Temple-Of-Apollo.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635213212045)

![Ortigia map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:uzeaFygi%7CAwHsJ%7DG%60%40EZkEDrAuGG_AO%5Co%40e%40Pk%40%7DC_%40Qi%40TQlBd%40Z%5B%7CFgKcByCuEyDT_AXCpHfHfCCnCuANf%40%7EDPlCeCl%40qCtEyDjDl%40rDqAItCdCB%5E%60Al%40E%5Ef%40%5CjAWhBPn%40%7E%40S%3FvDv%40tBlBBpKeE%7EC%60CxDkCbAwBf%40Nq%40pDsBfEgB%7E%40cBCsDp%40%7BIxEyAtCgB%60%40%5CtEm%40iDo%40LGe%40qRjDVjC%7B%40Z%7B%40wCgEdG&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=pmNCAHUleb6hkejMUM2kmj7vEZ4=)

### Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635213212045)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635213213825)

![Tiche map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:_bmaFiza%7CAm%40_%40U%7DDvAOBsEj%40sC%40kTi%40Pq%40i%40BsHgID%3FcFfEJJkLkGNA_Ag%40%40Ao%40h%40OiAcKiAq%40aVbAkBuKlBjAfAQ%5C%7D%40Us%40T%7DBs%40qA%5EKoBmCUyDaB_CgDoMp%40yCUyD%60EaC%7C%40oGjD%5BrENnC%7DAZ%5CKrBf%40%5CzMvBhKnDlLe%40xHuF%7CCN%7DBgQ%7CAKWcCbLqAHoCdBeBhVc%40nGqBnChOTjFvPkGjGp%5ClF%7ETmA%60D%7BAzIyEfC%7DDxHgJ%7EKuP%60YkWb%5CyJfKqPxJyKlAeCt%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=RYEHG0yi0IG66-wUmqK_UXNjSTQ=)

### Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635213213825)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=952515174506594304)

![Neapolis map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:e%7ChaF_ne%7CAq%40y%40QPsKkM%5DnCMLKUsDcQm%40eBQ_BsFoYzBoArBiAxAYvS%7DACuHGmSWwDbAaCvI%60B%7CGv%40I%60O%7EKt%40h%40RZpKeDdBr%40bC%60E%7ETyCjGiElCkB%60DmA%7EH%7BEhKqLlD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=etuAtkTmH-Na-zOlR4CLnA9CYgY=)

### Neapolis

While visiting Neapolis, you might make a stop by sights like Ear of Dionysius and Roman Amphitheatre of Syracuse.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=952515174506594304)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635213213857)

![Grottasanta map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ejmaFmhg%7CAiCIcKoHuCMaD%7C%40yDTyBpB_L%7DDmF%7DD%5EEGi%40f%40_%40KgBd%40FRgBm%40AAeAv%40TtAiC%5EiFk%40yDlAgDUe%40%5E%5DK%7D%40d%40s%40VqDjADBoAv%40CCu%40%5EGOaA%60A%7D%40u%40uIn%40_C%7D%40sBvCwAfAgBBu%40%5CCOyBl%40uBvGwCCz%40n%40AClApAh%40rEy%40dA%7DA%60FqALcCPSNf%40LOb%40cBrAj%40LaB%60Ic%40Ba%40hCm%40dAiAt%40MbBHd%40%5D%7C%40%60%40hIwBnDRpE%7B%40dC%40%5DgDdB%5BxBb%40HvBz%40i%40Xb%40%7CDaArA%3FlEfFfIp%40fJuEBiA%5Cr%40ZG%60EkCtBMs%40x%40bBr%40%7ECgB%7EDLDXnAi%40vALnCk%40BpAc%40%5C%5C%5Ee%40PXPfBe%40KnAq%40r%40dASr%40lA%5CGI%7ECZ%3FNjCh%40Vr%40nCYlBf%40%60%40xByAGaAXNQxBh%40vCaArBf%40%7C%40IdFoBpHaAa%40RiAiDuA%5Bk%40sMhFjClHcGz%40mBz%40y%40hB%7DTjJ_BmGuG%3FaDaCcCwFwGhF_QcKuBnA_AHa%40dAaETu%40q%40qAt%40ESkCfCaAHq%40_D_Bp%40Bn%40eEpAqCnC%7EEFtChOxDkBx%40dGaLzPl%40jIcBlC_BgAmDn%40a%40tC%5E%7EC&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=JWhQvZH-Tc8NoYmsBpvws_O2oWs=)

### Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635213213857)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635213214634)

![Acradina map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:isnaFklf%7CAAyApAkFM%7BCVc%40r%40%5Ed%40i%40P%60%40jB%40JoCu%40Ac%40b%40k%40E%3F%5Ba%40VHkAgAYoC%60%40%7B%40gBuCaBIuA%7BAgAVoBs%40%7BAaAYNwAi%40K%3Fe%40pF%7CD%7EK%7CDxBqBxDU%60D%7D%40tCLbKnHhCH_%40_D%60%40uClDo%40%7EAfAbBmCm%40kI%60L%7BPy%40eGyDjBuCiO_FGpCoCdEqACo%40%7EAq%40p%40%7EC%60AIjCgCDRpAu%40t%40p%40%60EU%60%40eA%7E%40ItBoA%7EPbKvGiFbCvF%60D%60CtG%3F%7EAlG%7CTkJx%40iBlB%7B%40bG%7B%40kCmHrMiFZj%40hDtAShA%60A%60%40yCbRv%40zFt%40f%40_AfCLdJ%7B%40%5EQz%40%5CxAWvBzArD%3FpH_VlBqEfCkRbHUkFoCiOoGpB%7DU%5EiBzAQ%7CCcLpAVbC%7DAJ%7CBfQ%7DCOyHtFmLd%40iKoD%7BMwBg%40%5DJsB%5B%5DoC%7CAsEOkDZ%7D%40nGaE%60C&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=eCMT0Ns9gsxOpEYlI-9q1Q5b4I8=)

### Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635213214634)

## Top Santa Lucia Hotel Reviews

### Maniace Boutique Hotel Ortigia UNA Esperienze

10/10 Excellent

"The hotel was impeccable, the staff were efficient, friendly and very helpful. Lovely location! We are already planning our next visit. "

[](https://expedia.ca/Syracuse-Hotels-Maniace-Boutique-Hotel-Ortigia.h109087329.Hotel-Information)

### Algila' Ortigia Charme Hotel

10/10 Excellent

"All good "

[](https://expedia.ca/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information)

### Lanterne Magiche Ortigia

10/10 Excellent

"Wonderful room. Spacious, good amenities, comfortable bed."

[](https://expedia.ca/Syracuse-Hotels-Lanterne-Magiche-Ortigia.h18704044.Hotel-Information)

### Palazzo Artemide - VRetreats

10/10 Excellent

"Very nice."

[](https://expedia.ca/Syracuse-Hotels-Palazzo-Artemide-VRetreats.h974007.Hotel-Information)

### Grand Hotel Villa Politi

10/10 Excellent

"Great old “grand hotel”. Beautiful property. "

[](https://expedia.ca/Syracuse-Hotels-Grand-Hotel-Villa-Politi.h1220650.Hotel-Information)

### Grand Hotel Ortigia Siracusa

10/10 Excellent

"breakfast was good"

[](https://expedia.ca/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information)

### Fortaleza Charme House

10/10 Excellent

"Cute hotel close to everything we wanted to see! Would definitely recommend!!"

[](https://expedia.ca/Syracuse-Hotels-Fortaleza-Charme-House.h105439006.Hotel-Information)

### Caportigia Boutique Hotel

10/10 Excellent

"Fine quality hotel with exceptional service. "

[](https://expedia.ca/Syracuse-Hotels-Caportigia-Boutique-Hotel.h17519019.Hotel-Information)

### Grand Hotel Des Ètrangers - The Leading Hotels of the World

10/10 Excellent

"Great hotel and saff"

[](https://expedia.ca/Syracuse-Hotels-Grand-Hotel-Des-Etrangers.h976389.Hotel-Information)

## Frequently asked questions

### What is Santa Lucia like?

> Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.

### Where is the best place to stay in Santa Lucia?

> Based on Expedia customer reviews, [Fortaleza Charme House](https://www.expedia.ca/Syracuse-Hotels-Fortaleza-Charme-House.h105439006.Hotel-Information) is the highest ranked property in Santa Lucia. This inn offers a beach bar and free WiFi. Other top choices in the neighborhood include [Giuggiulena Villa](https://www.expedia.ca/Syracuse-Hotels-Giuggiulena-Villa.h3091630.Hotel-Information) and [Caportigia Boutique Hotel](https://www.expedia.ca/Syracuse-Hotels-Caportigia-Boutique-Hotel.h17519019.Hotel-Information).

### How many hotels can I expect to find in Santa Lucia?

> Expedia has 278 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

### If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

> Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.

### What are the top things to see and do in Santa Lucia?

> Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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-   [Ognina Hotels](https://www.expedia.ca/Ognina-Hotels.d6182474.Travel-Guide-Hotels)
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-   [Plemmirio Hotels](https://www.expedia.ca/Plemmirio-Hotels.d6342256.Travel-Guide-Hotels)
-   [Priolo Gargallo Hotels](https://www.expedia.ca/Priolo-Gargallo-Hotels.d6344066.Travel-Guide-Hotels)
-   [Hostels in Province of Syracuse](https://www.expedia.ca/Province-Of-Syracuse-Hostels.d6052967-aaHostels.Travel-Guide-Accommodation)
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-   [Farmstay in Syracuse](https://www.expedia.ca/Syracuse-Agritourism.d4912-aaAgritourism.Travel-Guide-Accommodation)
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-   [Houseboats in Syracuse](https://www.expedia.ca/Syracuse-Houseboats.d4912-aaHouseboats.Travel-Guide-Accommodation)
-   [Inns in Syracuse](https://www.expedia.ca/Syracuse-Inns.d4912-aaInns.Travel-Guide-Accommodation)
-   [Resorts in Syracuse](https://www.expedia.ca/Syracuse-Resort-Hotels.d4912-aaResortHotels.Travel-Guide-Accommodation)
-   [Hotels near Syracuse Station](https://www.expedia.ca/Syracuse-Station-Hotels.d6043927.Travel-Guide-Hotels)
-   [Townhomes in Syracuse](https://www.expedia.ca/Syracuse-Townhomes.d4912-aaTownhomes.Travel-Guide-Accommodation)
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-   [Tiche Hotels](https://www.expedia.ca/Tiche-Syracuse-Hotels.0-n553248635213213825-0.Travel-Guide-Filter-Hotels)

-   [Flights to Syracuse](https://www.expedia.ca/Cheap-Flights-To-Syracuse.d4912.Travel-Guide-Flights)
-   [Flights from Syracuse](https://www.expedia.ca/lp/airports/qic/flights-from-syracuse-airport)
-   [Flights from Los Angeles to Syracuse](https://www.expedia.ca/lp/flights/178280/4912/los-angeles-to-syracuse)
-   [Flights from Syracuse](https://www.expedia.ca/lp/flights/4912/flights-from-syracuse)

-   [Lungomare di Ortigia](https://www.expedia.ca/Lungomare-Di-Ortigia-Ortigia.d6284111.Vacation-Attraction)
-   [Visit Province of Syracuse](https://www.expedia.ca/Province-Of-Syracuse.dx6052967)
-   [Syracuse Vacations](https://www.expedia.ca/Syracuse.d4912.Destination-Travel-Guides)
-   [Visit Syracuse](https://www.expedia.ca/Syracuse.dx4912)

-   [Alamo Rent A Car Rental Cars in Syracuse](https://www.expedia.ca/Alamo-Rent-A-Car-Car-Rentals-In-Syracuse.d4912-c6.Car-Rental-Guide-Suppliers)
-   [Avis Rental Cars in Syracuse](https://www.expedia.ca/Avis-Car-Rentals-In-Syracuse.d4912-c41.Car-Rental-Guide-Suppliers)
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-   [Car rental Syracuse](https://www.expedia.ca/Car-Rentals-In-Syracuse.d4912.Car-Rental-Guide)
-   [Enterprise Rental Cars in Syracuse](https://www.expedia.ca/Enterprise-Car-Rentals-In-Syracuse.d4912-c15.Car-Rental-Guide-Suppliers)
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-   [Van Car Rentals in Syracuse](https://www.expedia.ca/Van-Car-Rentals-In-Syracuse.d4912-tVan.Car-Rental-Guide-Class)

-   [Syracuse Vacation Rentals](https://www.expedia.ca/Syracuse-Vacation-Rentals.d4912.Travel-Guide-VacationRentals)

-   [Things to do in Syracuse](https://www.expedia.ca/Things-To-Do-In-Syracuse.d4912.Travel-Guide-Activities)

-   [Book Hotels in Santa Lucia on Expedia.it](https://www.expedia.it/Santa-Lucia-Siracusa-Hotel.0-n553248635213209885-0.Guida-Viaggi-Filtro-Hotel)