A colonial-style building with a bell tower, palm trees, and a paved walkway.

Santa Cruz Vacation Rentals

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Our top choices for Santa Cruz vacation rentals

1. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (107 reviews)
"Great location."
United States
Ruben
The price is CA $38
CA $38 total
Oct 13 - Oct 14
Apart Hotel Premium Suites Santa Cruz

2. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (121 reviews)
"great place to stay!"
United States
Luisa
The price is CA $59
CA $59 total
Oct 25 - Oct 26
Premium Suites Deluxe Aparthotel Equipetrol

3. Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
The price is CA $73
CA $73 total
Oct 13 - Oct 14
Equipetrol Suites Apart Hotel

4. POX: 24th Floor Green Tower | Luxury and Panoramic View

POX: 24th Floor Green Tower | Luxury and Panoramic View
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Very comfortable and nice view and the super clean"
United States
Carlos
The price is CA $107
CA $150 total
Oct 13 - Oct 14
POX: 24th Floor Green Tower | Luxury and Panoramic View

5. Terranova Suites

Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very good, (91 reviews)
"Easy to access"
United States
Dorothy
The price is CA $74
CA $74 total
Oct 13 - Oct 14
Terranova Suites

6. AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (3 reviews)
"Clean room, great staff "
Canada
Peter
The price is CA $49
CA $49 total
Oct 13 - Oct 14
AMERICA APARTMENTS

7. Apart Hotel Toborochi

Apart Hotel Toborochi
3.0 star property
Equipetrol
8.8 out of 10, Excellent, (61 reviews)
"Very comfortable and quiet place and very good location. "
United States
Luis
The price is CA $104
CA $104 total
Nov 1 - Nov 2
Apart Hotel Toborochi

8. Aqua: Loft Artistico Urbano

Aqua: Loft Artistico Urbano
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Excellent atencion todo muy comodo bonito limpio gracias"
United States
Nestor C.
The price is CA $43
CA $97 total
Oct 13 - Oct 14
Aqua: Loft Artistico Urbano

9. Menacho Apartment - Mangales Blue - Norte

Menacho Apartment - Mangales Blue - Norte
Santa Cruz de la Sierra
The price is CA $33
CA $47 total
Oct 13 - Oct 14
Menacho Apartment - Mangales Blue - Norte

10. Apartment with balcony, swimming pool, gym, co-work at Equipe

Apartment with balcony, swimming pool, gym, co-work at Equipe
Equipetrol
The price is CA $37
CA $78 total
Oct 19 - Oct 20
Apartment with balcony, swimming pool, gym, co-work at Equipe

11. Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed

Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed
Equipetrol
8.0 out of 10, Very good, (2 reviews)
The price is CA $36
CA $77 total
Oct 13 - Oct 14
Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed

12. Comfort in the best area of Santa Cruz—perfect for business travelers and tourists!!

Comfort in the best area of Santa Cruz—perfect for business travelers and tourists!!
Santa Cruz de la Sierra
The price is CA $37
CA $81 total
Oct 20 - Oct 21
Comfort in the best area of Santa Cruz—perfect for business travelers and tourists!!

13. Enchanting studio with AC in Santa Cruz de la Sierra

Enchanting studio with AC in Santa Cruz de la Sierra
Equipetrol
The price is CA $38
CA $67 total
Oct 13 - Oct 14
Enchanting studio with AC in Santa Cruz de la Sierra

14. Dpt. with Work Area / Swimming Pool / Gym / Sofa Bed

Dpt. with Work Area / Swimming Pool / Gym / Sofa Bed
Equipetrol
The price is CA $37
CA $78 total
Oct 19 - Oct 20
Dpt. with Work Area / Swimming Pool / Gym / Sofa Bed

15. COMODO MONOAMBIENTE EN EQUIPETROL CON PISCINA EN CONDOMINIO!

COMODO MONOAMBIENTE EN EQUIPETROL CON PISCINA EN CONDOMINIO!
Equipetrol
The price is CA $57
CA $96 total
Oct 13 - Oct 14
COMODO MONOAMBIENTE EN EQUIPETROL CON PISCINA EN CONDOMINIO!

16. 1 bedroom apartment, 2 TVs, 2 A/Cs, swimming pool & cowork

1 bedroom apartment, 2 TVs, 2 A/Cs, swimming pool & cowork
Equipetrol
The price is CA $40
CA $81 total
Oct 19 - Oct 20
1 bedroom apartment, 2 TVs, 2 A/Cs, swimming pool & cowork

17. Complete apartment in the best location in Santa Cruz, 5 min from Manzana 40.

Complete apartment in the best location in Santa Cruz, 5 min from Manzana 40.
Santa Cruz de la Sierra
The price is CA $43
CA $101 total
Oct 13 - Oct 14
Complete apartment in the best location in Santa Cruz, 5 min from Manzana 40.

18. Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC
Equipetrol
The price is CA $32
CA $68 total
Oct 24 - Oct 25
Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

19. Total Comfort in Santa Cruz

Total Comfort in Santa Cruz
Santa Cruz de la Sierra
The price is CA $36
CA $67 total
Oct 29 - Oct 30
Total Comfort in Santa Cruz

20. Inspiring views • Enveloping comfort

Inspiring views • Enveloping comfort
Equipetrol
The price is CA $41
CA $78 total
Oct 26 - Oct 27
Inspiring views • Enveloping comfort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Cruz. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

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Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we have vacation rentals in Santa Cruz near Santa Cruz Zoo, or you can go with a secluded option if you're looking for a relaxing stay. Discover why Santa Cruz is known for its shops. Make sure you have time to check out the cafes and zoo during your trip.

What are some of the best vacation home rentals in Santa Cruz?

Casa Vida: This highly rated vacation home rental in Santa Cruz is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. Some other top choices in Santa Cruz are Cozy 1-bedroom house in beautiful Santa Cruz de la Sierra with WiFi, AC and Seasonal House.

How many vacation rentals will I find in Santa Cruz?

With 23 Expedia vacation rentals, you're sure to find just the right place for your Santa Cruz stay.

What can I see and do in Santa Cruz?

Enjoy the outdoors at Arenal Park and Guembe Biocenter, or simply take in cultural attractions like Ethno-folkloric Museum and Cine Center. Plaza 24 de Septiembre and Blacutt Square are other places to visit while you're in town.

What are vacation rentals like in Santa Cruz?

Vacation rentals are private accommodations you can stay in for several days or more in Santa Cruz. Vacation rentals provide amenities such as laundry facilities and kitchens so you'll have everything you want. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from shared hotel elevators and busy reception areas while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a family trip.