Title: CA $589 Cheap Flights from Quito (UIO) to Santa Cruz (VVI) - Expedia.ca

  

![San Lorenzo Cathedral which includes a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# CA $589 Cheap Flights from Quito (UIO) to Santa Cruz (VVI)

[View CA $589 flight on Sat, Dec 6, 2025](https://expedia.ca/Flights-Search?trip=oneway&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:588.70&airProductToken=AQpgCi4IzIIBEgQyMzgzGJRyIItiKKuA_wIwsoH_AjhPQABYAWoCUVByCE9FRVFQWjZKCi4IzIIBEgQyNDA2GItiILVFKKiG_wIww4f_AjhPQAFYAWoCUVByCE9FRVFQWjZKEgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ)

-   [Roundtrip](?flightType=roundtrip)
-   [One-way](?flightType=oneway)
-   [Multi-city](?flightType=multicity)

### Travellers

Adults

ChildrenAges 2 to 17

InfantsYounger than 2

EconomyPremium economyBusiness classFirst class

Leaving from

Going to

Departing

Returning

Add a place to stay

Add a car

Direct flights only

## Popular airlines from Mariscal Sucre Intl. Airport (UIO) to Santa Cruz (VVI-Viru Viru Intl.)

-   ![Avianca](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg)
    
    Avianca
    
    [](https://www.expedia.ca/Flights-Search?leg1=from:uio,to:vvi,departure:16/11/2025TANYT&leg2=from:vvi,to:uio,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}])
-   ![LATAM Airlines Group](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg)
    
    LATAM Airlines Group
    
    [](https://www.expedia.ca/Flights-Search?leg1=from:uio,to:vvi,departure:16/11/2025TANYT&leg2=from:vvi,to:uio,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}])
-   ![Copa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg)
    
    Copa
    
    [](https://www.expedia.ca/Flights-Search?leg1=from:uio,to:vvi,departure:16/11/2025TANYT&leg2=from:vvi,to:uio,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}])

-   ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg)
    
    ### 
    
    Be in the know
    
    Get alerts if flight prices drop or rise\*
    
-   ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)
    
    ### 
    
    Book smarter
    
    Save up to 30% on select hotels after you book a flight\*
    
-   ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg)
    
    ### 
    
    Earn twice
    
    Earn your airline miles on top of our rewards
    
    [Sign in](https://www.expedia.ca/login)
    

## Cheap flights from Quito (UIO) to Santa Cruz (VVI)

Prices were available within the past 7 days and start at CA $589 for one-way flights and CA $1,157 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

All deals

One way

Roundtrip

![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,157

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1156.10&airProductToken=AQpgCi4IzIIBEgQyMzgzGJRyIItiKKuA_wIwsoH_AjhPQABYAWoCUVByCE9FRVFQWjZKCi4IzIIBEgQyNDA2GItiILVFKKiG_wIww4f_AjhPQAFYAWoCUVByCE9FRVFQWjZKEgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ)

![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,157

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1156.40&airProductToken=AQpgCi4IzIIBEgQyMzgzGJRyIItiKKuA_wIwsoH_AjhPQABYAWoCUVByCE9FRVFQWjZKCi4IzIIBEgQyNDA2GItiILVFKKiG_wIww4f_AjhPQAFYAWoCUVByCE9FRVFQWjZKCmAKLgjMggESBDI0MDcYtUUgi2Io1d2AAzDw3oADOFFAAFgBagJRUHIIUUVFUVBaNkoKLgjMggESBDIzODIYi2IglHIo3t-AAzDl4IADOFFAAVgBagJRUHIIUUVFUVBaNkoSCggBEAEYASoCTEEYASIECAEQASgCKAQoBjAB)

![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,187

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1186.40&airProductToken=AQpoCjIIwawBEgMxMjQYlHIgwTMo_fz-AjDh_f4COFNAAFgBagdDTEFTU0lDcghTRU9CMkJSRwoyCMGsARIDMTY3GMEzILVFKNaE_wIwy4b_AjhTQAFYAWoHQ0xBU1NJQ3IIU0VPQjJCUkcSCggBEAEYASoCTFIYASIECAEQASgCKAMoBDAB)

![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,234

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1233.10&airProductToken=AQpgCi4IzIIBEgQyMzgzGJRyIItiKKuA_wIwsoH_AjhPQABYAWoCUVByCE9FRVFQWjZKCi4IzIIBEgQyNDA2GItiILVFKKiG_wIww4f_AjhPQAFYAWoCUVByCE9FRVFQWjZKEgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ)

![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,266

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1265.70&airProductToken=AQpoCjIIwawBEgMxMjQYlHIgwTMo_fz-AjDh_f4COFNAAFgBagdDTEFTU0lDcghTRU9CMkJSRwoyCMGsARIDMTY3GMEzILVFKNaE_wIwy4b_AjhTQAFYAWoHQ0xBU1NJQ3IIU0VPQjJCUkcSCggBEAEYASoCTFIYASIECAEQASgCKAMoBDAB)

![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,267

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1266.90&airProductToken=AQpiCi8IwawBEgMxMjQYlHIgwTMo_fz-AjDh_f4COFdAAFgBagRGTEVYcghXRU9CM0JSRwovCMGsARIDMTY3GMEzILVFKNaE_wIwy4b_AjhXQAFYAWoERkxFWHIIV0VPQjNCUkcSCggBEAEYASoCTFIYASIECAEQASgCKAMoBDAB)

![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,294

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1294.00&airProductToken=AQpgCi4IzIIBEgQyMzgzGJRyIItiKKuA_wIwsoH_AjhPQABYAWoCU0xyCE9FRVNMWjZKCi4IzIIBEgQyNDA2GItiILVFKKiG_wIww4f_AjhPQAFYAWoCU0xyCE9FRVNMWjZKEgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ)

![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,347

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1346.20&airProductToken=AQpiCi8IwawBEgMxMjQYlHIgwTMo_fz-AjDh_f4COFdAAFgBagRGTEVYcghXRU9CM0JSRwovCMGsARIDMTY3GMEzILVFKNaE_wIwy4b_AjhXQAFYAWoERkxFWHIIV0VPQjNCUkcSCggBEAEYASoCTFIYASIECAEQASgCKAMoBDAB)

![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,348

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1347.20&airProductToken=AQpoCjIIwawBEgMxMDgYlHIgwTMoqIH_AjCHgv8COFNAAFgBagdDTEFTU0lDcghTRU9CMkJSRwoyCMGsARIDMTY3GMEzILVFKNaE_wIwy4b_AjhTQAFYAWoHQ0xBU1NJQ3IIU0VPQjJCUkcKaAoyCMGsARIDMTY2GLVFIMEzKOzcgAMw196AAzhTQABYAWoHQ0xBU1NJQ3IIU0VPQjJCUkcKMgjBrAESAzExNxjBMyCUcij-4IADMOLhgAM4U0ABWAFqB0NMQVNTSUNyCFNFT0IyQlJHEgoIARABGAEqAkxSGAEiBAgBEAEoAigDKAQwAQ)

![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,368

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1368.00&airProductToken=AQpoCjIIwawBEgMxMjQYlHIgwTMo_fz-AjDh_f4COFNAAFgBagdDTEFTU0lDcghTRU9CMkJSRwoyCMGsARIDMTY3GMEzILVFKNaE_wIwy4b_AjhTQAFYAWoHQ0xBU1NJQ3IIU0VPQjJCUkcSCggBEAEYASoCTFIYASIECAEQASgCKAMoBDAB)

![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,371

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1371.00&airProductToken=AQpgCi4IzIIBEgQyMzgzGJRyIItiKKuA_wIwsoH_AjhPQABYAWoCU0xyCE9FRVNMWjZKCi4IzIIBEgQyNDA2GItiILVFKKiG_wIww4f_AjhPQAFYAWoCU0xyCE9FRVNMWjZKEgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ)

![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,428

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1427.60&airProductToken=AQpgCi4IzIIBEgQyMzgzGJRyIItiKKuA_wIwsoH_AjhPQABYAWoCU0xyCE9FRVNMWjZKCi4IzIIBEgQyNDA2GItiILVFKKiG_wIww4f_AjhPQAFYAWoCU0xyCE9FRVNMWjZKCmAKLgjMggESBDI0MDcYtUUgi2Io1d2AAzDw3oADOFFAAFgBagJTTHIIUUVFU0xaNkoKLgjMggESBDIzODIYi2IglHIo3t-AAzDl4IADOFFAAVgBagJTTHIIUUVFU0xaNkoSCggBEAEYASoCTEEYASIECAEQASgCKAQoBjAB)

![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,448

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1447.60&airProductToken=AQpgCi4IzIIBEgQyMzgzGJRyIItiKKuA_wIwsoH_AjhPQABYAWoCS0RyCE9FRUtEWjhKCi4IzIIBEgQyNDA2GItiILVFKKiG_wIww4f_AjhPQAFYAWoCS0RyCE9FRUtEWjhKEgoIARABGAEqAkxBGAEiBAgBEAEoAigDKAQwAQ)

![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,508

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1508.00&airProductToken=AQpiCi8IwawBEgMxMDgYlHIgwTMoqIH_AjCHgv8COFdAAFgBagRGTEVYcghXRU9CM0JSRwovCMGsARIDMTY3GMEzILVFKNaE_wIwy4b_AjhXQAFYAWoERkxFWHIIV0VPQjNCUkcKYgovCMGsARIDMTY2GLVFIMEzKOzcgAMw196AAzhXQABYAWoERkxFWHIIV0VPQjNCUkcKLwjBrAESAzExNxjBMyCUcij-4IADMOLhgAM4V0ABWAFqBEZMRVhyCFdFT0IzQlJHEgoIARABGAEqAkxSGAEiBAgBEAEoAigDKAQwAQ)

![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif)

Sat, Dec 6 - Fri, Dec 26

UIO

Quito

VVI

Santa Cruz

CA $1,525

Roundtrip

found 3 days ago

[](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:UIO,to:VVI,departure:06/12/2025TANYT&leg2=from:VVI,to:UIO,departure:26/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1524.60&airProductToken=AQpgCi4IzIIBEgQyMzgzGJRyIItiKKuA_wIwsoH_AjhPQABYAWoCS0RyCE9FRUtEWjhKCi4IzIIBEgQyNDA2GItiILVFKKiG_wIww4f_AjhPQAFYAWoCS0RyCE9FRUtEWjhKEgoIARABGAEqAkxBGAEiBAgBEAEoAigDKAQwAQ)

## Frequently asked questions

### How much is a flight from Mariscal Sucre Intl. Airport (UIO) to VVI?

> The lowest price advertised for a round-trip flight between UIO and Viru Viru Intl. Airport (VVI) is CA $1,157. But you better act soon. This figure is based on fares available within the last 7 days on Expedia for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

### Do I need to pay a cancellation fee if I cancel my flight from UIO to Viru Viru Intl. Airport (VVI)?

> Most flights can be cancelled online, but every airline has a different set of terms and conditions. If you do need to cancel your flight, check out our [Customer Service Portal](https://www.expedia.ca/helpcenter) and follow the instructions.

### How do I find cheap flights from Quito International Airport to Viru Viru Intl. Airport (VVI) that have flexible change policies?

> Plenty of carriers offer the option to move your flight at no extra charge. All you pay is the cost difference between the two flights. When searching for UIO to Viru Viru flights, you'll see a "No change fees" filter for you to tick.

### How many hours is the flight from Mariscal Sucre Intl. Airport (UIO) to Viru Viru?

> There are lots of ways to make the 5 hours and 51 minutes between Mariscal Sucre Intl. Airport (UIO) and Viru Viru fly by. If you want to be productive, sort through your camera roll or delete all those backed-up emails. A snooze also helps pass the time!

### How far is the flight from Quito International Airport to Viru Viru?

> Around 2,600 kilometres separates Tababela and Santa Cruz, so pack some entertainment to keep you occupied for a couple of hours. That action-packed novel you're eager to read will do the trick.

### Which airlines fly direct from Mariscal Sucre Intl. Airport (UIO) to Viru Viru?

> Unfortunately, there are no airlines that directly fly between Quito International Airport and Viru Viru Intl. Airport (VVI). You'll have to book a flight with one or more stops.

### Are UIO to Viru Viru Intl. Airport (VVI) flight tickets cheaper when they're purchased at the last minute?

> Fares from Mariscal Sucre Intl. Airport (UIO) to Viru Viru Intl. Airport (VVI) are available up to 12 months before departure on Expedia. And although you may occasionally score great last-minute deal, it's not something you should count on. Also, booking your flights ahead of time means you'll have more choices — and you can avoid ending up with the dreaded middle seat! We frequently update our fares to make sure you get the biggest bargains, so keep checking in for all the latest specials.

## Travel information

| Origin airport | Mariscal Sucre Intl. |
| --- | --- |
| Destination airport | Viru Viru Intl. |
| Roundtrip price | CA $1,156 |
| Distance | 2547 km |

## Book with confidence

### Quito to Santa Cruz Flights

**The easy way to book your flights from Quito to Santa Cruz** 

With Expedia, it’s simple to find and book flights to Santa Cruz from Quito whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Viru Viru Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Quito to Santa Cruz today, tomorrow, or this week.  

**Save dollars with cheap flights from Mariscal Sucre Intl., UIO to Viru Viru Intl., VVI** 

Sort your search results by price to find great deals on your flight from Quito to Santa Cruz—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Santa Cruz from Quito currently is just CA $1,157 rising to CA $1,525.  

Here are more money-saving tips: 

-   Fly in December when flight prices are normally at their lowest 
-   Book about a month to 6 weeks before you travel for the best prices to Santa Cruz  
-   Avoid peak season and weekends when flights can cost more
-   Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
-   One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

**Reasons to choose Expedia for your flight to Santa Cruz from Quito** 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Santa Cruz with Expedia today.

## Explore a world of travel with Expedia

-   Flights

-   [Flights from South Lake Tahoe to Santa Cruz](https://www.expedia.ca/lp/flights/10150/6053940/south-lake-tahoe-to-santa-cruz)
-   [Flights from Abingdon to Santa Cruz](https://www.expedia.ca/lp/flights/10278/6053940/abingdon-to-santa-cruz)
-   [Flights from San Carlos to Santa Cruz](https://www.expedia.ca/lp/flights/10834/6053940/san-carlos-to-santa-cruz)
-   [Flights from El Paso to Santa Cruz](https://www.expedia.ca/lp/flights/1129/6053940/el-paso-to-santa-cruz)
-   [Flights from Ewo to Santa Cruz](https://www.expedia.ca/lp/flights/1182/6053940/ewo-to-santa-cruz)
-   [Flights from McHenry to Santa Cruz](https://www.expedia.ca/lp/flights/131592/6053940/mchenry-to-santa-cruz)
-   [Flights from General Roca to Santa Cruz](https://www.expedia.ca/lp/flights/1351/6053940/general-roca-to-santa-cruz)
-   [Flights from Juneau to Santa Cruz](https://www.expedia.ca/lp/flights/1715/6053940/juneau-to-santa-cruz)
-   [Flights from Plaine Magnien to Santa Cruz](https://www.expedia.ca/lp/flights/178017/6053940/plaine-magnien-to-santa-cruz)
-   [Flights from Toronto to Santa Cruz](https://www.expedia.ca/lp/flights/178314/6053940/toronto-to-santa-cruz)
-   [Flights from Vancouver to Santa Cruz](https://www.expedia.ca/lp/flights/178315/6053940/vancouver-to-santa-cruz)
-   [Flights from Cancun to Santa Cruz](https://www.expedia.ca/lp/flights/179995/6053940/cancun-to-santa-cruz)
-   [Flights from Edmonton to Santa Cruz](https://www.expedia.ca/lp/flights/180002/6053940/edmonton-to-santa-cruz)
-   [Flights from Juiz de Fora to Santa Cruz](https://www.expedia.ca/lp/flights/181125/6053940/juiz-de-fora-to-santa-cruz)
-   [Flights from Brampton Island to Santa Cruz](https://www.expedia.ca/lp/flights/181609/6053940/brampton-island-to-santa-cruz)
-   [Flights from St. John's to Santa Cruz](https://www.expedia.ca/lp/flights/181832/6053940/st-johns-to-santa-cruz)
-   [Flights from Mammoth Lakes to Santa Cruz](https://www.expedia.ca/lp/flights/2363/6053940/mammoth-lakes-to-santa-cruz)
-   [Flights from Mount Cook to Santa Cruz](https://www.expedia.ca/lp/flights/2390/6053940/mount-cook-to-santa-cruz)
-   [Flights from Minot to Santa Cruz](https://www.expedia.ca/lp/flights/2392/6053940/minot-to-santa-cruz)
-   [Flights from Misurata to Santa Cruz](https://www.expedia.ca/lp/flights/2410/6053940/misurata-to-santa-cruz)
-   [Flights from Perugia to Santa Cruz](https://www.expedia.ca/lp/flights/2762/6053940/perugia-to-santa-cruz)
-   [Flights from San Rafael to Santa Cruz](https://www.expedia.ca/lp/flights/303/6053940/san-rafael-to-santa-cruz)
-   [Flights from Santa Rosa to Santa Cruz](https://www.expedia.ca/lp/flights/3036/6053940/santa-rosa-to-santa-cruz)
-   [Flights from San Pedro Sula to Santa Cruz](https://www.expedia.ca/lp/flights/3075/6053940/san-pedro-sula-to-santa-cruz)
-   [Flights from Santa Maria to Santa Cruz](https://www.expedia.ca/lp/flights/3224/6053940/santa-maria-to-santa-cruz)
-   [Flights from Ouvea to Santa Cruz](https://www.expedia.ca/lp/flights/3668/6053940/ouvea-to-santa-cruz)
-   [Flights from Nanaimo to Santa Cruz](https://www.expedia.ca/lp/flights/3908/6053940/nanaimo-to-santa-cruz)
-   [Flights from Kamloops to Santa Cruz](https://www.expedia.ca/lp/flights/3979/6053940/kamloops-to-santa-cruz)
-   [Flights from Whistler to Santa Cruz](https://www.expedia.ca/lp/flights/4115/6053940/whistler-to-santa-cruz)
-   [Flights from Saskatoon to Santa Cruz](https://www.expedia.ca/lp/flights/4117/6053940/saskatoon-to-santa-cruz)
-   [Flights from Alor to Santa Cruz](https://www.expedia.ca/lp/flights/412/6053940/alor-to-santa-cruz)
-   [Flights from London to Santa Cruz](https://www.expedia.ca/lp/flights/4127/6053940/london-to-santa-cruz)
-   [Flights from Abbotsford to Santa Cruz](https://www.expedia.ca/lp/flights/4128/6053940/abbotsford-to-santa-cruz)
-   [Flights from Amazon Bay to Santa Cruz](https://www.expedia.ca/lp/flights/483/6053940/amazon-bay-to-santa-cruz)
-   [Flights from Salinas to Santa Cruz](https://www.expedia.ca/lp/flights/500230/6053940/salinas-to-santa-cruz)
-   [Flights from Wallis Lake to Santa Cruz](https://www.expedia.ca/lp/flights/553248634374909947/6053940/wallis-lake-to-santa-cruz)
-   [Flights from Howitt to Santa Cruz](https://www.expedia.ca/lp/flights/553248634382194191/6053940/howitt-to-santa-cruz)
-   [Flights from Dooen to Santa Cruz](https://www.expedia.ca/lp/flights/553248634384088998/6053940/dooen-to-santa-cruz)
-   [Flights from Bulgakovskiy to Santa Cruz](https://www.expedia.ca/lp/flights/553248635949793764/6053940/bulgakovskiy-to-santa-cruz)
-   [Flights from Bellavista to Santa Cruz](https://www.expedia.ca/lp/flights/553248635973467087/6053940/bellavista-to-santa-cruz)
-   [Flights from Dieppe to Santa Cruz](https://www.expedia.ca/lp/flights/57817/6053940/dieppe-to-santa-cruz)
-   [Flights from Oakland to Santa Cruz](https://www.expedia.ca/lp/flights/601762/6053940/oakland-to-santa-cruz)
-   [Flights from Santa Barbara to Santa Cruz](https://www.expedia.ca/lp/flights/602277/6053940/santa-barbara-to-santa-cruz)
-   [Flights from Bocas del Toro to Santa Cruz](https://www.expedia.ca/lp/flights/6023445/6053940/bocas-del-toro-to-santa-cruz)
-   [Flights from Vero Beach to Santa Cruz](https://www.expedia.ca/lp/flights/6023660/6053940/vero-beach-to-santa-cruz)
-   [Flights from Madison to Santa Cruz](https://www.expedia.ca/lp/flights/602704/6053940/madison-to-santa-cruz)
-   [Flights from Little Rock to Santa Cruz](https://www.expedia.ca/lp/flights/602841/6053940/little-rock-to-santa-cruz)
-   [Flights from Halifax to Santa Cruz](https://www.expedia.ca/lp/flights/602873/6053940/halifax-to-santa-cruz)
-   [Flights from Bellingham to Santa Cruz](https://www.expedia.ca/lp/flights/602922/6053940/bellingham-to-santa-cruz)
-   [Flights from Harrisburg - Hershey to Santa Cruz](https://www.expedia.ca/lp/flights/602958/6053940/harrisburg-hershey-to-santa-cruz)
-   [Flights from Fresno to Santa Cruz](https://www.expedia.ca/lp/flights/602988/6053940/fresno-to-santa-cruz)
-   [Flights from Peoria to Santa Cruz](https://www.expedia.ca/lp/flights/602999/6053940/peoria-to-santa-cruz)
-   [Flights from Apodaca to Santa Cruz](https://www.expedia.ca/lp/flights/603208/6053940/apodaca-to-santa-cruz)
-   [Flights from Cape Town to Santa Cruz](https://www.expedia.ca/lp/flights/6046820/6053940/cape-town-to-santa-cruz)
-   [Flights from Puerto Montt to Santa Cruz](https://www.expedia.ca/lp/flights/6053664/6053940/puerto-montt-to-santa-cruz)
-   [Flights from Quito to Santa Cruz](https://www.expedia.ca/lp/flights/6053672/6053940/quito-to-santa-cruz)
-   [Flights from Santa Rosa to Santa Cruz](https://www.expedia.ca/lp/flights/6053725/6053940/santa-rosa-to-santa-cruz)
-   [Flights from Carlsbad to Santa Cruz](https://www.expedia.ca/lp/flights/6054977/6053940/carlsbad-to-santa-cruz)
-   [Flights from Genoa to Santa Cruz](https://www.expedia.ca/lp/flights/6055038/6053940/genoa-to-santa-cruz)
-   [Flights from Sikeston to Santa Cruz](https://www.expedia.ca/lp/flights/6058766/6053940/sikeston-to-santa-cruz)
-   [Flights from Pinamar to Santa Cruz](https://www.expedia.ca/lp/flights/6126518/6053940/pinamar-to-santa-cruz)
-   [Flights from Winnipeg to Santa Cruz](https://www.expedia.ca/lp/flights/6141041/6053940/winnipeg-to-santa-cruz)
-   [Flights from Santa Cruz das Flores to Santa Cruz](https://www.expedia.ca/lp/flights/6142203/6053940/santa-cruz-das-flores-to-santa-cruz)
-   [Flights from Manado to Santa Cruz](https://www.expedia.ca/lp/flights/6142306/6053940/manado-to-santa-cruz)
-   [Flights from Weno to Santa Cruz](https://www.expedia.ca/lp/flights/6142787/6053940/weno-to-santa-cruz)
-   [Flights from Arad to Santa Cruz](https://www.expedia.ca/lp/flights/6158/6053940/arad-to-santa-cruz)
-   [Flights from Ashland to Santa Cruz](https://www.expedia.ca/lp/flights/6170/6053940/ashland-to-santa-cruz)
-   [Flights from Dodge City to Santa Cruz](https://www.expedia.ca/lp/flights/6212601/6053940/dodge-city-to-santa-cruz)
-   [Flights from São José dos Campos to Santa Cruz](https://www.expedia.ca/lp/flights/6221736/6053940/sao-jose-dos-campos-to-santa-cruz)
-   [Flights from Valbo to Santa Cruz](https://www.expedia.ca/lp/flights/6263425/6053940/valbo-to-santa-cruz)
-   [Flights from Wuerselen to Santa Cruz](https://www.expedia.ca/lp/flights/6300587/6053940/wuerselen-to-santa-cruz)
-   [Flights from Independence and Mango Creek to Santa Cruz](https://www.expedia.ca/lp/flights/6336194/6053940/independence-and-mango-creek-to-santa-cruz)
-   [Flights from Batticaloa to Santa Cruz](https://www.expedia.ca/lp/flights/6341931/6053940/batticaloa-to-santa-cruz)
-   [Flights from Baños del Inca to Santa Cruz](https://www.expedia.ca/lp/flights/6345760/6053940/banos-del-inca-to-santa-cruz)
-   [Flights from Santa Rosa to Santa Cruz](https://www.expedia.ca/lp/flights/6351758/6053940/santa-rosa-to-santa-cruz)
-   [Flights from Babo to Santa Cruz](https://www.expedia.ca/lp/flights/6463/6053940/babo-to-santa-cruz)
-   [Flights from South Burlington to Santa Cruz](https://www.expedia.ca/lp/flights/6739/6053940/south-burlington-to-santa-cruz)
-   [Flights from Glentanner to Santa Cruz](https://www.expedia.ca/lp/flights/7524/6053940/glentanner-to-santa-cruz)
-   [Flights from East Haven to Santa Cruz](https://www.expedia.ca/lp/flights/7792/6053940/east-haven-to-santa-cruz)
-   [Flights from Tuban to Santa Cruz](https://www.expedia.ca/lp/flights/9384/6053940/tuban-to-santa-cruz)
-   [Flights from Papa Westray to Santa Cruz](https://www.expedia.ca/lp/flights/9461/6053940/papa-westray-to-santa-cruz)
-   [Flights from Camiri (CAM) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/cam/srz/camiri-to-santa-cruz)
-   [Flights from Upland (CCB) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/ccb/srz/upland-to-santa-cruz)
-   [Flights from Greenville (GSP) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/gsp/srz/greenville-to-santa-cruz)
-   [Flights from Honolulu (HNL) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/hnl/srz/honolulu-to-santa-cruz)
-   [Flights from Lafayette (LFT) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/lft/srz/lafayette-to-santa-cruz)
-   [Flights from Lagos (LOS) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/los/srz/lagos-to-santa-cruz)
-   [Flights from Manchester (MHT) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/mht/srz/manchester-to-santa-cruz)
-   [Flights from Monterey (MRY) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/mry/srz/monterey-to-santa-cruz)
-   [Flights from Oakland (OAK) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/oak/srz/oakland-to-santa-cruz)
-   [Flights from Oak Harbor (ODW) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/odw/srz/oak-harbor-to-santa-cruz)
-   [Flights from Palm Springs (PSP) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/psp/srz/palm-springs-to-santa-cruz)
-   [Flights from Los Angeles (QLA) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/qla/srz/los-angeles-to-santa-cruz)
-   [Flights from Reno (RNO) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/rno/srz/reno-to-santa-cruz)
-   [Flights from San Antonio (SAT) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/sat/srz/san-antonio-to-santa-cruz)
-   [Flights from San Luis Obispo (SBP) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/sbp/srz/san-luis-obispo-to-santa-cruz)
-   [Flights from Shanghai (SHA) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/sha/srz/shanghai-to-santa-cruz)
-   [Flights from Santa Maria (SMX) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/smx/srz/santa-maria-to-santa-cruz)
-   [Flights from Syracuse (SYR) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/syr/srz/syracuse-to-santa-cruz)
-   [Flights from Topeka (TOP) to Santa Cruz (SRZ)](https://www.expedia.ca/lp/flights/top/srz/topeka-to-santa-cruz)

\*Available to Expedia members.