CA $277 Cheap Flights from Guayaquil (GYE) to Santa Cruz (VVI)

View CA $277 flight on Mon, Sep. 29, 2025Opens in a new window

Popular airlines from Jose Joaquin de Olmedo Intl. Airport (GYE) to Santa Cruz (VVI-Viru Viru Intl.)

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Cheap flights from Guayaquil (GYE) to Santa Cruz (VVI)

Prices were available within the past 7 days and start at CA $277 for one-way flights and CA $547 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Mon, Sep. 29 - Wed, Oct. 8
GYE
Guayaquil
VVI
Santa Cruz
CA $547 Roundtrip, found 4 days ago
CA $547
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Mon, Sep. 29 from Guayaquil to Santa Cruz, returning Wed, Oct. 8, priced at CA $547 found 4 days ago
LATAM Airlines Group
Mon, Sep. 29 - Wed, Oct. 8
GYE
Guayaquil
VVI
Santa Cruz
CA $601 Roundtrip, found 4 days ago
CA $601
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Mon, Sep. 29 from Guayaquil to Santa Cruz, returning Wed, Oct. 8, priced at CA $601 found 4 days ago
LATAM Airlines Group
Mon, Sep. 29 - Wed, Oct. 8
GYE
Guayaquil
VVI
Santa Cruz
CA $622 Roundtrip, found 4 days ago
CA $622
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Mon, Sep. 29 from Guayaquil to Santa Cruz, returning Wed, Oct. 8, priced at CA $622 found 4 days ago
LATAM Airlines Group
Mon, Sep. 29 - Wed, Oct. 8
GYE
Guayaquil
VVI
Santa Cruz
CA $675 Roundtrip, found 4 days ago
CA $675
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Mon, Sep. 29 from Guayaquil to Santa Cruz, returning Wed, Oct. 8, priced at CA $675 found 4 days ago
LATAM Airlines Group
Mon, Sep. 29 - Wed, Oct. 8
GYE
Guayaquil
VVI
Santa Cruz
CA $851 Roundtrip, found 4 days ago
CA $851
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Mon, Sep. 29 from Guayaquil to Santa Cruz, returning Wed, Oct. 8, priced at CA $851 found 4 days ago
LATAM Airlines Group
Mon, Sep. 29 - Wed, Oct. 8
GYE
Guayaquil
VVI
Santa Cruz
CA $926 Roundtrip, found 4 days ago
CA $926
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Mon, Sep. 29 from Guayaquil to Santa Cruz, returning Wed, Oct. 8, priced at CA $926 found 4 days ago
avianca
Mon, Sep. 29 - Wed, Oct. 8
GYE
Guayaquil
VVI
Santa Cruz
CA $964 Roundtrip, found 4 days ago
CA $964
Roundtrip
found 4 days ago
Select avianca flight, departing Mon, Sep. 29 from Guayaquil to Santa Cruz, returning Wed, Oct. 8, priced at CA $964 found 4 days ago
avianca
Mon, Sep. 29 - Wed, Oct. 8
GYE
Guayaquil
VVI
Santa Cruz
CA $1,012 Roundtrip, found 4 days ago
CA $1,012
Roundtrip
found 4 days ago
Select avianca flight, departing Mon, Sep. 29 from Guayaquil to Santa Cruz, returning Wed, Oct. 8, priced at CA $1,012 found 4 days ago
Flight from Guayaquil to Santa Cruz (GYE - VVI) route information
Origin airport
Jose Joaquin de Olmedo Intl.
Destination airport
Viru Viru Intl.
Roundtrip price
CA $546
Distance
2497 km

Guayaquil to Santa Cruz Flights

The easy way to book your flights from Guayaquil to Santa Cruz 

With Expedia, it’s simple to find and book flights to Santa Cruz from Guayaquil whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 11 airlines that cover this route. There are nonstop flights to Viru Viru Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Guayaquil to Santa Cruz today, tomorrow, or this week.  

 

Save dollars with cheap flights from Jose Joaquin de Olmedo Intl., GYE to Viru Viru Intl., VVI 

Sort your search results by price to find great deals on your flight from Guayaquil to Santa Cruz—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Santa Cruz from Guayaquil currently is just CA $547 rising to CA $1,012.  

Here are more money-saving tips: 

  • Fly in September when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Santa Cruz  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Santa Cruz from Guayaquil 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Santa Cruz with Expedia today.

Frequently asked questions

How much is a flight from Airport of Guayaquil to Viru Viru Intl. Airport (VVI)?
Round-trip journeys from Airport of Guayaquil to Viru Viru start from CA $547. This price is based on fares available within the last 7 days on Expedia for flights departing within the next year — book today so you don't miss out. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from GYE to Viru Viru Intl. Airport (VVI)?
The majority of flights can be conveniently cancelled online, but whether you incur a fee all comes down to your airline. If you do have to cancel your getaway, follow the easy instructions in the Customer Service Portal.
How do I find cheap flights from GYE to Viru Viru Intl. Airport (VVI) that have flexible change policies?
Select our "No change fees" filter to find flexible ticketing options for your flight from GYE to Viru Viru Intl. Airport (VVI). This allows you to snag a fantastic price in advance and still have the freedom to reschedule without any extra fees. If the new flight costs more, you'll just cover the difference.
How many hours is the flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to VVI?
To get through the 9 hours and 31 minutes flight time between GYE and Viru Viru Intl. Airport (VVI), it's wise to be prepared. A smartphone loaded up with your favourite playlists is a wonderful start.
How far is the flight from Airport of Guayaquil to Viru Viru?
You'll be cruising at altitude for a while, as the flight distance from Guayas to Santa Cruz is 2,500 kilometres. Set up a playlist of your favourite tunes before leaving home to keep yourself entertained during your journey.
Which airlines fly direct from GYE to Viru Viru?
Unfortunately, there are no airlines that directly fly between Airport of Guayaquil and Viru Viru. You'll need to book a flight with at least one stop.
Are Airport of Guayaquil to Viru Viru flight tickets cheaper when they're purchased at the last minute?
Last-minute bookings from GYE to Viru Viru can be hit-or-miss. It is possible to find a bargain, but you could also miss out completely! If you'd rather start your trip planning ahead of time, Expedia compares flight deals up to a year in advance. Just bear in mind that not all airlines publish their prices so far in advance. Our advice? Check back often as updates are made frequently.

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