Title: Book the Best Santa Cruz LUXURY Hotels - Upscale Hotels in Santa Cruz | Expedia.ca [Santa Cruz Travel Guide](https://expedia.ca/Santa-Cruz.dx6053940)[Hotels in Santa Cruz](https://expedia.ca/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz](https://expedia.ca/Santa-Cruz-Vacation-Rentals.d6053940.Travel-Guide-VacationRentals)[Flights to Santa Cruz](https://expedia.ca/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights)[Things to do in Santa Cruz](https://expedia.ca/Things-To-Do-In-Santa-Cruz.d6053940.Travel-Guide-Activities)[Santa Cruz Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz.d6053940.Car-Rental-Guide)[Santa Cruz Vacation Packages](https://expedia.ca/Santa-Cruz.d6053940.Destination-Travel-Guides) ![San Lorenzo Cathedral which includes a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Luxury Hotels Tonight [Jan 30 - Jan 31](https://www.expedia.ca/Hotel-Search?regionId=6053940&startDate=2026-01-30&endDate=2026-01-31&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Jan 31 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6053940&startDate=2026-01-31&endDate=2026-02-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6053940&startDate=2026-01-30&endDate=2026-02-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6053940&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Santa Cruz luxury hotels ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/9d61826a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/7e3a6616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; garden views](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/01205665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camino Real Hotel [](https://www.expedia.ca/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) Santa Cruz 8.8/10 Excellent (414 reviews) "Rooms were very clean and service was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JESUS CA $162 CA $162 total Mar 1 - Mar 2 [](https://www.expedia.ca/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Massages](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/6b27e04a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/1b68b7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/ffb227c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/d2cd08da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swissôtel Santa Cruz De La Sierra [](https://www.expedia.ca/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) Santa Cruz 9.2/10 Wonderful (82 reviews) "Beautiful hotel" ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Joanna CA $170 CA $170 total Feb 15 - Feb 16 [](https://www.expedia.ca/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/02f3d22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/e8e161c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/4f7a4f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/f930f88b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Santa Cruz de la Sierra Hotel [](https://www.expedia.ca/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) Santa Cruz 9.0/10 Wonderful (213 reviews) "Great hotel, food and location albeit a little expensive " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reinaldo CA $124 CA $124 total Feb 7 - Feb 8 [](https://www.expedia.ca/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/efaab5ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/a8bc5939.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/dcf17d3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, free cabanas](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/78f237b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TRYP by Wyndham Santa Cruz [](https://www.expedia.ca/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) Santa Cruz 9.2/10 Wonderful (152 reviews) "Yes! Room was spotless. The staff are very patient and professional. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pluetina CA $134 CA $134 total Jan 31 - Feb 1 [](https://www.expedia.ca/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/efe5b8af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/864143db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/fb4d1503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/b607f479.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Novotel Santa Cruz De La Sierra [](https://www.expedia.ca/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) Santa Cruz 9.2/10 Wonderful (105 reviews) "Luxurious hotel,very chic and beautiful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cristhian CA $142 CA $142 total Mar 1 - Mar 2 [](https://www.expedia.ca/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/794bff22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/e77454e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/34d33eda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia [](https://www.expedia.ca/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) Santa Cruz 9.2/10 Wonderful (259 reviews) "Our room was clean and comfortable. The staff were friendly and very helpful!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ann CA $99 CA $99 total Feb 6 - Feb 7 [](https://www.expedia.ca/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-13&endDate=2026-02-14®ionId=6053940&adults=2&sort=LUXURY&star=40,50&openPlayBack=true) ## Find out more about Santa Cruz ### Santa Cruzand its attractions for luxury travelers Santa Cruz, Bolivia, is a vibrant city that offers a unique blend of culture, luxury, and adventure for discerning travellers. Begin your exploration at the stunning Biocentro Güembé, where you can enjoy luxurious spa treatments amidst lush gardens and pools, perfect for unwinding after a day of exploration. For art enthusiasts, the Museo de Arte Contemporáneo offers an impressive collection of modern works, showcasing the region's artistic flair. A visit to the historic Plaza 24 de Septiembre is a must, where you can relax in elegant cafes while soaking up the local atmosphere and vibrant street life. Adventure seekers can take a day trip to the nearby Amboró National Park, where guided luxury tours reveal breathtaking landscapes and unique wildlife, ensuring an unforgettable experience. For accommodation, the exclusive Zona Equipetrol area is highly recommended, featuring upscale hotels that provide exceptional service and amenities. Here, you can enjoy exquisite dining options and vibrant nightlife, all within a stone's throw of your luxurious lodgings, making it an ideal base for a lavish Santa Cruz getaway. ### Find the best luxury hotels and resorts in Santa Cruz For travellers seeking a luxurious experience in Santa Cruz, Bolivia, these top hotels offer exceptional amenities and unmatched comfort, ensuring a splendid stay. [**Hampton by Hilton Santa Cruz/Equipetrol, Bolivia**](https://www.expedia.ca/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) - **Why it's great for a luxury retreat:** The Hampton by Hilton Santa Cruz/Equipetrol is perfect for luxury seekers, featuring a popular guest review rating of 9.2\. This hotel provides room service and a warm fireplace, creating a cozy and inviting atmosphere for guests. With a dedicated concierge service, every need is anticipated, ensuring a seamless stay for all travellers. - **Other amenities:** Guests can enjoy a complimentary buffet breakfast each morning, along with accessible off-street parking. The hotel also features a fitness centre for those looking to stay active. Additional offerings include a grocery shopping service, a snack bar, and accessibility features, making it a well-rounded choice for luxury travel. - **Nearby attractions:** Santa Cruz Zoo - 1.8 km, Patio Design LifeStyle Center - 1.6 km, Ventura Mall - 0.7 km [**Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel**](https://www.expedia.ca/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) - **Why it's great for a luxury retreat:** Located in the heart of Santa Cruz, Los Tajibos stands out with a remarkable guest review rating of 9.0\. This luxurious hotel features a 24-hour restaurant and room service, ensuring guests can enjoy a delightful dining experience at their convenience. With premium bedding, guests can expect restful nights, complemented by the attentive concierge service that meets every traveller's desire. - **Other amenities:** The hotel also offers a range of spa services, including hydrotherapy treatments, body scrubs, and couples treatment rooms, enhancing the overall luxury experience. Other features include a hot tub, private balconies, and a fitness centre for those who wish to maintain their routine. Additional conveniences such as free buffet breakfast, self-parking, and nearby shopping districts elevate the level of comfort for guests. - **Nearby attractions:** Santa Cruz Zoo - 1.4 km, Patio Design LifeStyle Center - 1.4 km, Ventura Mall - 2.3 km [**Marriott Santa Cruz de la Sierra Hotel**](https://www.expedia.ca/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) - **Why it's great for a luxury retreat:** The Marriott Santa Cruz de la Sierra Hotel epitomises luxury, a stellar review rating of 9.0\. Featuring spacious executive rooms with access to an exclusive lounge, guests can enjoy enhanced privacy and comfort. The onsite spa offers a variety of treatments, while room service ensures dining can be enjoyed in the comfort of your own space. - **Other amenities:** The hotel also features an outdoor pool with sun loungers, tennis courts for an active lifestyle, and beautiful rooftop gardens for relaxation. Additional benefits include housekeeping services, free toiletries, fitness facilities, and self-parking, all designed to provide a straightforward experience for discerning travellers. - **Nearby attractions:** Santa Cruz Zoo - 2.4 km, Patio Design LifeStyle Center - 1.9 km, Ventura Mall - 0.7 km [**Camino Real Hotel**](https://www.expedia.ca/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) - **Why it's great for a luxury retreat:** The Camino Real Hotel is a splendid choice for luxury travellers, an impressive guest review rating of 8.8\. With a stunning poolside bar and a swim-up bar, guests can indulge in refreshing cocktails while basking in the sun. The hotel also features a beautifully designed garden-view restaurant, perfect for enjoying exquisite meals in a serene environment, complemented by 24-hour room service and a dedicated concierge to cater to every need. - **Other amenities:** Guests can unwind in the onsite spa with treatment rooms offering massage services, or relax in the indoor and outdoor pools, complete with hydromassage showerheads and pool umbrellas. The hotel also provides an array of conveniences such as free buffet breakfast, airport transportation, and babysitting services, making it ideal for both relaxation and convenience. With a shopping district nearby, guests can easily explore local offerings. - **Nearby attractions:** Santa Cruz Zoo - 2 km, Patio Design LifeStyle Center - 2.2 km, Ventura Mall - 0.8 km [**Sun Hotel**](https://www.expedia.ca/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) - **Why it's great for a luxury retreat:** The Sun Hotel is an excellent option for luxury travellers, with an excellent guest review rating of 8.2\. This hotel offers 24-hour room service and designer toiletries, ensuring guests feel pampered throughout their stay. With a concierge on hand, all requests can be accommodated, making this hotel an appealing choice for those seeking a refined experience. - **Other amenities:** Guests can indulge in spa services, including manis and pedis, reflexology, and body treatments. The outdoor pool and hot tub provide a perfect setting for relaxation, while the hotel also offers free buffet breakfast. Other conveniences include airport transportation, a sauna, and a beautiful garden area for leisurely strolls. - **Nearby attractions:** Play Land Amusement Park - 2.6 km, Univalle - 8.8 km ## Top Santa Cruz Hotel Reviews ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Indeed this is a First Class hotel. Beautiful lobby, great dining area, beautiful pool, ample rooms. " [](https://expedia.ca/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ## Frequently asked questions ### What are the top-rated luxury hotels in Santa Cruz? > The 5-star Novotel Santa Cruz De La Sierra, with a 9.2 rating, is located within a shopping district and offers premium bedding and rainfall showerheads. Reviewers frequently praise the comfortable pillows and excellent restaurant. > > > The 5-star Marriott Santa Cruz de la Sierra Hotel, rated 9.0, provides executive rooms with lounge access and on-site tennis facilities. Customers consistently highlight the great service. > > > The 4.5-star Swissôtel Santa Cruz De La Sierra, with a 9.2 rating, features a poolside bar and premium bedding. Its facilities are frequently described as excellent, with a great location and good showers. ### Which area of Santa Cruz is best to stay in for luxury hotels? > Equipetrol is known for its modern infrastructure and upscale amenities, making it the city's most exclusive district. It's characterised by wide, tree-lined streets, contemporary high-rise buildings, and a wide array of high-end shopping centres, gourmet restaurants, and sophisticated nightlife options. It's a well-maintained area that feels quite distinct from the more traditional city centre. > > > For couples seeking a refined and comfortable stay, Equipetrol is an excellent choice. The area offers numerous luxury hotels with amenities such as rooftop pools, fine dining restaurants, and high-end fitness equipment. It's superb for those who appreciate convenience and quality, with many establishments providing excellent service and a tranquil environment away from the city's busiest parts. > > > Business travellers will also find Equipetrol highly suitable. Many corporate offices are located within or close to the district, and the hotels often feature extensive business facilities, including conference rooms and executive lounges. ### How much does a luxury hotel in Santa Cruz cost? ### Which luxury hotels in Santa Cruz are good for families? > The 5-star Novotel Santa Cruz De La Sierra, with a 9.2 rating, provides 24-hour room service and premium bedding, ensuring comfort for all family members. Its location within a shopping district is also convenient. > > > The Marriott Santa Cruz de la Sierra Hotel, also 5-star with a 9.0 rating, offers spacious suites and an executive lounge, providing ample space and exclusive services for families. On-site tennis facilities can also be a valuable amenity. > > > The 4.5-star Camino Real Hotel, rated 8.8, features a garden-view restaurant and a poolside bar, suitable for family dining and relaxation. Reviewers frequently praise its excellent location and super helpful staff. ### What are the best luxury hotels in Santa Cruz with a pool? > The 5-star Novotel Santa Cruz De La Sierra, with a 9.2 rating, provides both outdoor and children's pools, making it suitable for families. Guests frequently praise the comfortable pillows and excellent restaurant. > > > The 5-star Marriott Santa Cruz de la Sierra Hotel, rated 9.0, features an outdoor pool. Customers consistently highlight the great service. > > > The 4.5-star Swissôtel Santa Cruz De La Sierra, also with a 9.2 rating, offers an outdoor pool and a poolside bar. Reviewers often praise the excellent facilities and great location. ### Are there any top luxury hotels near Ventura Mall? > The 4.5-star Camino Real Hotel, with an 8.8 rating, is known for its excellent location, which places guests within a shopping district. Reviewers frequently praise the exceptionally helpful and kind staff. The hotel also features an on-site art gallery, a swim-up bar, and a restaurant with garden views. > > > The 4.5-star Swissôtel Santa Cruz De La Sierra, boasting a 9.2 rating, is also conveniently located. Guests consistently highlight the excellent facilities and comfortable bedding, with specific mentions of good beds and showers. The hotel offers a poolside bar and 24-hour room service. ### What luxury activities and experiences are there in Santa Cruz? > Equipetrol is a contemporary district characterised by wide avenues, new high-rise buildings, and a generally polished appearance. It's located just north of the city centre, making it easily accessible while feeling distinct. You'll find many of the city's finest hotels, gourmet restaurants, and exclusive boutiques along its main streets, particularly around Avenida San Martín. > > > For couples seeking a sophisticated escape, Equipetrol offers numerous opportunities for high-end dining, from innovative international cuisine to refined local dishes. Many hotels in this area feature rooftop pools and bars, great for enjoying the city views. The neighbourhood also has several upscale shopping centres, such as Ventura Mall, where you can find designer brands and specialty shops. > > > Travellers looking for premium wellness and relaxation will find Equipetrol particularly appealing. Many luxury hotels here provide comprehensive spa services, including massages and beauty treatments. ### How can I save on a luxury hotel in Santa Cruz with Expedia? ### Is it cheaper to book a luxury Santa Cruz hotel and flights as a package? ### Can I cancel my luxury hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - [Family Hotels in Santa Cruz ](https://www.expedia.ca/Destinations-In-Santa-Cruz-Family-Hotel.0-0-d6297178-tFamilyHotel.Hotel-Filter-Destinations) - [Santa Cruz Hotels ](https://www.expedia.ca/Destinations-In-Santa-Cruz.d6297178.Hotel-Destinations) - [Hotels near El Trompillo ](https://www.expedia.ca/El-Trompillo-Airport-Hotels.0-aSRZ-0.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in La Guardia ](https://www.expedia.ca/La-Guardia-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d6347124-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Flights from El Trompillo ](https://www.expedia.ca/lp/airports/srz/flights-from-el-trompillo-airport) - 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