Book The Best Hotels in Santa Cruz for 2026 from CA $35 - Fully Refundable Options

Our top choices for Santa Cruz hotels

Isak Hotel & Golf Airport

Rionegro

Garret

CA $112 total

Jun 5 - Jun 6

Hotel Lagoon

Rionegro

Antonio

CA $177 total

Jun 10 - Jun 11

Hotel Santiago de Arma

Rionegro

Mario

CA $135 total

Jun 28 - Jun 29

Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments

Movich Hotel Las Lomas

Rionegro

Gary

CA $200 total

Jun 21 - Jun 22

Travelers Rio Verde Living Suites

Rionegro

Robert

CA $93 total

Jun 2 - Jun 3

Dann Carlton Medellin Hotel

El Poblado

julianus

CA $112 total

Jun 8 - Jun 9

Hotel Living 35 Suites by Growing Group

La América

Felix

CA $65 total

Jun 17 - Jun 18

Medellinn The Blooming Hotel

El Poblado

Rosanna

CA $71 total

Jun 17 - Jun 18

Calle Flora Hotel by Jalo

El Poblado

Tabatha

CA $116 total

Jun 6 - Jun 7

Marquee Hotel

El Poblado

Timothy

CA $164 total

Jun 8 - Jun 9

Hotel Provenza Garden

El Poblado

Carlos

CA $78 total

Jun 5 - Jun 6

Hotel Once22

Sabaneta

Alfonso

CA $88 total

Jun 20 - Jun 21

Diez Hotel Categoria Colombia

El Poblado

Jeremy

CA $187 total

Jun 23 - Jun 24

Fairfield by Marriott Medellin Sabaneta

Sabaneta

Lynn

CA $101 total

Jun 5 - Jun 6

Arame Hotel

Envigado

Benjamin

CA $95 total

Jun 2 - Jun 3

Hotel Celestino Boutique

El Poblado

Patricia

CA $134 total

Jun 3 - Jun 4

The Click Clack Hotel Medellin

El Poblado

Emily

CA $257 total

Jun 16 - Jun 17

Landmark Hotel

El Poblado

Raza

CA $121 total

Jun 16 - Jun 17

Hotel Ryo 74B Suites by Growing Group

Laureles

Michael

CA $56 total

Jun 21 - Jun 22

York Medellin, Curio Collection by Hilton

El Poblado

Naomi

CA $222 total

Jun 30 - Jul 1

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Top Santa Cruz Hotel Reviews

Diez Hotel Categoria Colombia

8/10 Good

"Hotel bueno pero las camas deben ser mas cómodas De todo lo demás muy bueno"

V Grand Hotel, a member of Radisson Individuals

4/10 Poor

"The hotel has a unique architectural design which would make for a place of warmth and tranquility. However, the callous attitude of the front desk staff, especially the lady with purple hair, made the experience undesirable. We were initially placed on the 4th floor by the purple hair lady who knew quite well that the wifi wasn't working on the 2nd, 3rd and 4th floors. She scoffed at our request to have the issue addressed. Our persistence through highlighting our professional and post-graduate obligations eventually yielded a positive outcome and the room was changed. At breakfast, coffee service would've been a rarity if Fabian was the only person serving; we were often ignored. Thanks to Derly, Jeisson and Santiago for their courtesy and warmth. The cleaning staff was also excellent attending to the room every day. At checkout we were charged for consuming contents from the mini bar in the room. Note, we were never informed of this at check-in. We spent 7 days receiving uncouth and unwelcoming behavior led by the lady with purple hair. Whilst, I try to refrain myself from crying racism, I think it's best to serve my dark-skinned brothers and sisters, especially those who don't speak spanish, by saying, "Try another hotel." I urge the management team to address these issues before it robs your hotel of the spectacular service the Radisson group is known for and strives to maintain, and tarnish the natural beauty and radiant colors of the Colombian experience."

Calle Flora Hotel by Jalo

8/10 Good

"Great new hotel in the perfect area!! Everything is legit at walking distance! Only thing i do recommend is probably a more bigger option when it comes to the breakfast! They have a little of everything but realistically it’s just recalentado, soup and eggs and a small plate of bacon, but they have the basics also they need more options in the pool, they should have music, a bar and a better seating area, it’s like just so boring tbh"

Dann Carlton Medellin Hotel

8/10 Good

"While this hotel is marketed as a 5 star hotel, I don't necessarily believe that it is. It's lovely but I doubt I'd stay there again. The staff were friendly and they had an excellent selection available for breakfast. The location however was extremely convenient and was the main reason for the selection."

More cheap stays in Santa Cruz

Hostal Lleras Calle 8 - Hostel

Calle 8 # 37A - 59 Medellín Antioquia

CA $35

CA $35 total

Jun 8 - Jun 9

8.4/10 Very Good! (146 reviews)

Frequently asked questions

What is the best area to stay in Santa Cruz?

The best area to stay in Santa Cruz is El Poblado, particularly around Parque Lleras and Provenza.

El Poblado is the main hub for visitors, known for its upscale amenities and well-maintained streets. Parque Lleras is a central point, surrounded by restaurants, cafes, and boutiques. Just a short walk away, Provenza offers a slightly more relaxed atmosphere with its tree-lined streets and independent shops. This area is very walkable, making it easy to explore on foot.

Couples often find El Poblado ideal for a romantic and enjoyable trip. The numerous high-quality restaurants and stylish cocktail bars provide plenty of options for evenings out. Many hotels in this area offer amenities like rooftop pools and excellent dining, superb for a comfortable stay.

For solo travellers, El Poblado provides a convenient and friendly base. Its central location means easy access to public transport, including the efficient Medellín Metro, making it simple to explore other parts of the city.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.

How can I save on a Santa Cruz hotel booking with Expedia?

Members always get our best prices. Find our best Santa Cruz hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.

How much is the nightly rate at a Santa Cruz hotel?

Prices for hotels in Santa Cruz often vary, but you can find a great deal from CA $35 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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Our top choices for Santa Cruz hotels

Isak Hotel & Golf Airport

Hotel Lagoon

Hotel Santiago de Arma

Movich Hotel Las Lomas

Travelers Rio Verde Living Suites

Dann Carlton Medellin Hotel

Hotel Living 35 Suites by Growing Group

Medellinn The Blooming Hotel

Calle Flora Hotel by Jalo

Marquee Hotel

Hotel Provenza Garden

Hotel Once22

Diez Hotel Categoria Colombia

Fairfield by Marriott Medellin Sabaneta

Arame Hotel

Hotel Celestino Boutique

The Click Clack Hotel Medellin

Landmark Hotel

Hotel Ryo 74B Suites by Growing Group

York Medellin, Curio Collection by Hilton

Top Santa Cruz Hotel Reviews

Diez Hotel Categoria Colombia

More cheap stays in Santa Cruz

Hostal Lleras Calle 8 - Hostel

Frequently asked questions

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