Title: Visit Santa Fe de Antioquia: Best of Santa Fe de Antioquia Tourism | Expedia Travel Guide - Expedia.ca [Hotels in Santa Fe de Antioquia](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels.d6143343.Travel-Guide-Hotels)[Vacation Rentals in Santa Fe de Antioquia](https://expedia.ca/Santa-Fe-De-Antioquia-Vacation-Rentals.d6143343.Travel-Guide-VacationRentals)[Flights to Santa Fe de Antioquia](https://expedia.ca/Cheap-Flights-To-Santa-Fe-De-Antioquia.d6143343.Travel-Guide-Flights)[Things to do in Santa Fe de Antioquia](https://expedia.ca/Things-To-Do-In-Santa-Fe-De-Antioquia.d6143343.Travel-Guide-Activities)[Santa Fe de Antioquia Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Fe-De-Antioquia.d6143343.Car-Rental-Guide)[Santa Fe de Antioquia Vacation Packages](https://expedia.ca/Santa-Fe-De-Antioquia.d6143343.Destination-Travel-Guides) # Santa Fe de Antioquia ## Travel Guide ![Beautiful colonial town](https://images.trvl-media.com/place/6143343/29cd441c-37d2-4bc5-a439-b1f1c5081a7c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Beautiful colonial town](https://images.trvl-media.com/place/6143343/29cd441c-37d2-4bc5-a439-b1f1c5081a7c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Nice short getaway from Medellín ](https://images.trvl-media.com/place/6143343/01ea9c79-dbb2-489f-a472-444d0cc1b37c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Nice hotel here ](https://images.trvl-media.com/place/6143343/86f5167c-8e76-408a-a433-172b140dfffd.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santa Fe](https://images.trvl-media.com/place/6143343/027e25da-55d7-4660-bb8e-99afd7963f23.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santa Fe de Antioquia Where to stay Things to do ### Where to stay in Santa Fe de Antioquia ![Beautiful colonial town](https://images.trvl-media.com/place/6143343/29cd441c-37d2-4bc5-a439-b1f1c5081a7c.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Zona Colonial If you're spending some time in Zona Colonial, Bolivar Square and Cathedral of Santa Fe de Antioquia are top sights worth seeing. [](https://expedia.ca/Santa-Fe-De-Antioquia-Zona-Colonial.dx553248635976394869) - Santa Fe de Antioquia Hotel Deals - Vacation Rentals in Santa Fe de Antioquia ![Arde La Selva](https://images.trvl-media.com/lodging/109000000/108290000/108283700/108283692/38d256db_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Arde La Selva km 1 via anza vereda obregon Santa Fe de Antioquia Antioquia CA $205 CA $205 total Feb 9 - Feb 10 Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo Juan del Corral and Bolivar Square ... 9.8/10 Exceptional! (24 reviews) The room was clean, the property was absolutely gorgeous, the staff excells in customer service Reviewed on Jan 16, 2026 [](https://expedia.ca/Hotel-Search?startDate=09%2F02%2F2026&endDate=10%2F02%2F2026&selected=108283692&PinnedHotelID=108283692&HadPinnedHotel=true®ionId=6143343) ![Hotel San Sebastian del Tonusco](https://images.trvl-media.com/lodging/90000000/89940000/89933300/89933227/4fdd9de9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel San Sebastian del Tonusco Carrera 9 Santa Fe de Antioquia Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo Juan del Corral and Bolivar Square ... 8.8/10 Excellent! (43 reviews) Two nice swimming calls, very friendly staff, safe, walk to town Reviewed on Nov 20, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=17%2F02%2F2026&endDate=18%2F02%2F2026&selected=89933227&PinnedHotelID=89933227&HadPinnedHotel=true®ionId=6143343) [](https://expedia.ca/Hotel-Search?startDate=17%2F02%2F2026&endDate=18%2F02%2F2026&selected=89933227&PinnedHotelID=89933227&HadPinnedHotel=true®ionId=6143343) ![Curazao Hotel](https://images.trvl-media.com/lodging/92000000/91820000/91816900/91816803/78fff740_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Curazao Hotel 14-47 Cl. 10 Santa Fe de Antioquia Antioquia CA $72 CA $72 total Feb 8 - Feb 9 Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free WiFi, and onsite spa services. Popular attractions Cathedral of Santa Fe de Antioquia ... 9.8/10 Exceptional! (8 reviews) Location. Staff attitude Reviewed on Dec 29, 2025 [](https://expedia.ca/Hotel-Search?startDate=08%2F02%2F2026&endDate=09%2F02%2F2026&selected=91816803&PinnedHotelID=91816803&HadPinnedHotel=true®ionId=6143343) [See all 456 properties in Santa Fe de Antioquia](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=04%2F02%2F2026&endDate=05%2F02%2F2026®ionId=6143343) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Finca hotel mi refugio](https://images.trvl-media.com/lodging/120000000/119570000/119565600/119565573/07edb325_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Finca hotel mi refugio 1541 Camino real Santa Fé de Antioquia Antioquia Stay at this cottage in Santa Fe de Antioquia. Enjoy free WiFi, free parking, and a garden. Popular attractions Museo Juan del Corral and Bolivar Square are ... [](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-Finca-Hotel-Mi-Refugio.h119565573.Hotel-Information) ![SANTA FE DE ANTIOQUIA](https://images.trvl-media.com/lodging/109000000/108750000/108747200/108747191/9b39b471_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### SANTA FE DE ANTIOQUIA 111 Cl. 8 Santa Fe de Antioquia Antioquia Stay at this aparthotel in Santa Fe de Antioquia. Enjoy free WiFi, 6 outdoor pools, and a garden. Popular attractions Cathedral of Santa Fe de Antioquia and ... 8/10 Very Good! (1 review) Todo Ok Reviewed on Feb 10, 2025 [](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-SANTA-FE-DE-ANTIOQUIA.h108747191.Hotel-Information) ![Villa Cantaleta Just 3 Block from Old Town](https://images.trvl-media.com/lodging/108000000/107040000/107031200/107031122/60414b0e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Villa Cantaleta Just 3 Block from Old Town Santa Fe de Antioquia Antioquia Stay at this villa in Santa Fe de Antioquia. Enjoy laundry facilities and air conditioning. Popular attractions Casa Atanasio Girardot and Cathedral of Santa ... everything looks as promised in the app, except for the payment options, I ended up paying cash at the location due to technical communication between the app ant the owner Reviewed on Dec 2, 2024 [](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-Villa-Cantaleta-Just-3-Block-From-Old-Town.h107031122.Hotel-Information) [See all properties in Santa Fe de Antioquia](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6143343&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa Fe de Antioquia hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=2026-02-03&endDate=2026-02-04)[Feb 3 - Feb 4](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=2026-02-03&endDate=2026-02-04) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=2026-02-04&endDate=2026-02-05)[Feb 4 - Feb 5](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=2026-02-04&endDate=2026-02-05) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=06%2F02%2F2026&endDate=08%2F02%2F2026)[Feb 6 - Feb 8](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=06%2F02%2F2026&endDate=08%2F02%2F2026) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[Feb 13 - Feb 15](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) ### Popular places to visit #### Bridge of the West After visiting Bridge of the West, make a plan to see the other sights and activities in Santa Fe de Antioquia. Make time to visit the cathedral and monuments while you're in the area. [](https://expedia.ca/Bridge-Of-The-West-Antioquia.d553248634304588117.Vacation-Attraction) #### Bolivar Square Learn about the local history of Santa Fe de Antioquia with a stop at Bolivar Square. Stroll along the riverfront or experience the area's festivals. [](https://expedia.ca/Bolivar-Square-Zona-Colonial.d6264618.Vacation-Attraction) #### Iglesia de Santa Bárbara After visiting Iglesia de Santa Bárbara, make a plan to see the other sights and activities in Santa Fe de Antioquia. Wander the riverfront and parks while you're in the area. [](https://expedia.ca/Iglesia-De-Santa-Barbara-Zona-Colonial.d553248621532376358.Vacation-Attraction) #### Cathedral of Santa Fe de Antioquia You can learn about the history of Santa Fe de Antioquia with a trip to Cathedral of Santa Fe de Antioquia. Make time to visit the monuments and cathedral while you're in the area. [](https://expedia.ca/Cathedral-Of-Santa-Fe-De-Antioquia-Zona-Colonial.d6264612.Vacation-Attraction) #### Casa Atanasio Girardot You can spend an afternoon browsing the exhibits at Casa Atanasio Girardot during your trip to Santa Fe de Antioquia. [](https://expedia.ca/Casa-Atanasio-Girardot-Zona-Colonial.d553248635998043782.Vacation-Attraction) #### Church of Our Lady of Chinquinquira Church of Our Lady of Chinquinquira is just one of the places to see in Santa Fe de Antioquia, so why not enjoy the other things to explore during your travels? Amble around the area's riverfront or visit its monuments. [](https://expedia.ca/Church-Of-Our-Lady-Of-Chinquinquira-Zona-Colonial.d6264614.Vacation-Attraction) ### Things to do ![Santa Fe de Antioquia Tour with Western Bridge Visit](https://mediaim.expedia.com/localexpert/4228231/74b99ee1-9016-4644-94fe-12a3c57f2d3e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe de Antioquia Tour with Western Bridge Visit CA $53 per adult [](https://expedia.ca/things-to-do/santa-fe-de-antioquia-tour-with-western-bridge-visit.a4228231.activity-details) ![Panoramic with outfit](https://mediaim.expedia.com/localexpert/47252859/c432a359-45b4-4dcb-8547-aca61f4d1bb1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Coffee tour in Medellín with tastings and transportation CA $90 per adult [](https://expedia.ca/things-to-do/coffee-tour-in-medellin-with-tastings-and-transportation.a47252859.activity-details) ![Horseback Riding Tour and Coffee Tour with Lunch and Refreshment](https://mediaim.expedia.com/localexpert/50756334/1f9f6580-6b1d-4aa0-be66-471f1a3eed66.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Horseback Riding Tour and Coffee Tour with Lunch and Refreshment CA $96 per adult [](https://expedia.ca/things-to-do/horseback-riding-tour-and-coffee-tour-with-lunch-and-refreshment.a50756334.activity-details) [See all activities in Santa Fe de Antioquia](https://expedia.ca/Things-To-Do-In-Santa-Fe-De-Antioquia.d6143343.Travel-Guide-Activities) ## Cities near Santa Fe de Antioquia ![Sopetrán, Antioquia, Colombia; June 29, 2024: Ceiling interior details of Our Lady of the Assumption in the main square of Sopetrán town.](https://images.trvl-media.com/place/3000006094/2656bb7d-5503-45f6-ae38-4003a1e0d109.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Sopetrán ## Explore a world of travel with Expedia - 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