Downtown South San Francisco

San Francisco

Photo by Catherine Edejer-McCormick

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Things to do


Downtown South San Francisco Hotel Deals

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd, South San Francisco, CA
The price is CA $166 per night from Jul 27 to Jul 28
CA $166
CA $194 total
Jul 27 - Jul 28
includes taxes & fees
Stay at this 3-star business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast ...
8/10 Very Good! (2,025 reviews)
"There’s a Denny’s right next door. Convenient location. Costco, Subway, Hertz, KFC, Taco Bell within walking distance. Cleaning lady a little too eager to get into our room. Very humid so carpet always felt damp. Maybe hardwood or laminate floors would be better suited. Ladies at front desk were ..."

Reviewed on Jul. 20, 2025

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
The price is CA $184 per night from Aug 24 to Aug 25
CA $184
CA $217 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
8.8/10 Excellent! (4,352 reviews)
"Very happy with our recent stay. Very convenient to local restaurants. Wonderful staff"

Reviewed on Jul. 22, 2025

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
The price is CA $154 per night from Aug 4 to Aug 5
CA $154
CA $237 total
Aug 4 - Aug 5
includes taxes & fees
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (6,615 reviews)
"Excellent"

Reviewed on Jul. 24, 2025

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
The price is CA $149 per night from Aug 24 to Aug 25
CA $149
CA $175 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,504 reviews)
"Very nice"

Reviewed on Jul. 21, 2025

Hilton San Francisco Financial District
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
The price is CA $231 per night from Jul 25 to Jul 26
CA $231
CA $336 total
Jul 25 - Jul 26
includes taxes & fees
Stay at this 4-star eco-certified hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,763 reviews)
"Very clean and the staff is friendly"

Reviewed on Jul. 21, 2025

Hyatt Regency San Francisco
InterContinental Mark Hopkins by IHG

InterContinental Mark Hopkins by IHG

4 out of 5
999 California Street, San Francisco, CA
The price is CA $196 per night from Jul 27 to Jul 28
CA $196
CA $282 total
Jul 27 - Jul 28
includes taxes & fees
Stay at this 4-star luxury hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,052 reviews)
"I always stay there in SF."

Reviewed on Jul. 21, 2025

InterContinental Mark Hopkins by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown South San Francisco

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Noe Valley

5/5(1 area review)

Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city.

Noe Valley
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Mission District

4/5(5 area reviews)

Mission District is a destination travelers like for its bars, and you might hop aboard the metro at 16th Street Mission Station or 24th Street Mission Station to explore sights like San Francisco Public Library.

Mission District
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Eureka Valley

If you're spending time in Eureka Valley, check out sights like Castro Street or Castro Theatre and hop on the metro to see more the city at Castro Station or 17th St & Castro St Stop.

Eureka Valley
Ocean Beach showing landscape views, a sandy beach and general coastal views

Outer Sunset

When in Outer Sunset and the surrounding area, you'll want to check out sights like Ocean Beach or San Francisco Botanical Garden and hop on the metro to see more the city at Judah St & 34th Ave Stop or Judah Street & Sunset Boulevard Station.

Outer Sunset
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Sunset District

3.5/5(10 area reviews)

Travelers choose Sunset District for its pristine beaches. Hop aboard the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop and check out top sights like Ocean Beach.

Sunset District
South of Market showing skyline, a city and city views

South of Market

3.5/5(292 area reviews)

Oracle Park and Chase Center are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.

South of Market

Downtown South San Francisco

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