Title: 10 Best Hotels in Downtown South San Francisco, San Francisco for 2026 | Expedia.ca

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![Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015](https://images.trvl-media.com/place/553248635976481411/4dd74f8a-dfcd-4623-817e-767c96ff0c5c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/553248635976481411/4dd74f8a-dfcd-4623-817e-767c96ff0c5c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

Tonight

[Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 7 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Downtown South San Francisco hotels

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/5d196618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Multiple Beds, Accessible, Non Smoking (Mobility/Hearing Impaired Accessible)](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/6c7a44bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/4becccdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/f426e9e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham San Francisco Airport N

[](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information)

Downtown South San Francisco

8.0/10

Very good

(2,020 reviews)

"Pleasant stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alok

CA $138

CA $162 total

includes taxes & fees

Feb 21 - Feb 22

[](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/08473f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/b9912bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/aeecf8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/72fd4af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Inn By The SFO

[](https://www.expedia.ca/San-Francisco-Hotels-Inn-By-The-SFO.h1139289.Hotel-Information)

Downtown South San Francisco

7.8/10

Good

(1,002 reviews)

"Everything great. Good location close to airport and walking distance to coffee, market, and restaurants. Try shabu shack!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gabriel

[](https://www.expedia.ca/San-Francisco-Hotels-Inn-By-The-SFO.h1139289.Hotel-Information)

![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/779a738f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/b1cfa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/466a0c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/380e42eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Airport Inn

[](https://www.expedia.ca/San-Francisco-Hotels-Airport-Inn.h11974670.Hotel-Information)

Downtown South San Francisco

8.8/10

Excellent

(984 reviews)

"Very clean room, friendly staff and secure parking."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christopher

CA $129

CA $152 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/San-Francisco-Hotels-Airport-Inn.h11974670.Hotel-Information)

![Deluxe Room](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/1e2e26cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/d205a5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/c5aa34b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/60ad2a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Miller Apartments

[](https://www.expedia.ca/San-Francisco-Hotels-Miller-Apartments.h91116819.Hotel-Information)

Downtown South San Francisco

7.4/10

Good

(15 reviews)

"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "

![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg)

Kasey

CA $128

CA $252 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/San-Francisco-Hotels-Miller-Apartments.h91116819.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/75f20517.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/fb03adf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/4e4ef19d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/cd59b3af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Riu Plaza Fisherman's Wharf

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information)

16.8 km from Downtown South San Francisco

9.0/10

Wonderful

(7,296 reviews)

"excellent breakfast and location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Leslie

CA $168

CA $254 total

includes taxes & fees

Feb 10 - Feb 11

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information)

![Outdoor pool, a heated pool, open 8 AM to 8 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/4fd95a3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/63a5d8bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/9e50e45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/18d49d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Handlery Union Square Hotel

[](https://www.expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information)

14.5 km from Downtown South San Francisco

8.8/10

Excellent

(2,858 reviews)

"Friendly staff great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tiffany

CA $172

CA $202 total

includes taxes & fees

Feb 28 - Mar 1

[](https://www.expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information)

![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/575b2d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/381993a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/ac2abcd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/9765cbda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Caza Fisherman's Wharf

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information)

16.6 km from Downtown South San Francisco

9.0/10

Wonderful

(3,821 reviews)

"Nice hotel and great staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tomohiro

CA $185

CA $283 total

includes taxes & fees

Feb 11 - Feb 12

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/74bf4ae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, 1 King Bed with Sofa bed | Living room](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/a9e1104a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/c107a1f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/51c31a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Westin San Francisco Airport

[](https://www.expedia.ca/San-Francisco-Hotels-The-Westin-San-Francisco-Airport.h4705.Hotel-Information)

6.9 km from Downtown South San Francisco

8.8/10

Excellent

(1,981 reviews)

"Very nice hotel! The restaurant food and drinks were amazing !"

![Japan](https://a.travel-assets.com/egds/marks/flags/jp.svg)

Risa

CA $152

CA $215 total

includes taxes & fees

Feb 28 - Mar 1

[](https://www.expedia.ca/San-Francisco-Hotels-The-Westin-San-Francisco-Airport.h4705.Hotel-Information)

![Building design](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/5ec6ba9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/5d60bf4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/71a1e5ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/cbb2553d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Aluxor SFO

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Aluxor-SFO.h902027.Hotel-Information)

3.7 km from Downtown South San Francisco

8.6/10

Excellent

(2,743 reviews)

"Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephanie

CA $134

CA $162 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Aluxor-SFO.h902027.Hotel-Information)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/5971a3e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/a67c7266.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/06ec7d41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/8e61a8e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Golden Gateway by IHG

[](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information)

14.8 km from Downtown South San Francisco

9.0/10

Wonderful

(5,240 reviews)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jorge

CA $169

CA $199 total

includes taxes & fees

Feb 16 - Feb 17

[](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/890000/880800/880752/92b747fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Non Smoking, Microwave](https://images.trvl-media.com/lodging/1000000/890000/880800/880752/6c9aac82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/890000/880800/880752/596146db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/890000/880800/880752/2b3f6e45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Inn & Suites San Mateo - San Francisco Airport

[](https://www.expedia.ca/San-Francisco-Hotels-Best-Western-Coyote-Point-Inn.h880752.Hotel-Information)

11.8 km from Downtown South San Francisco

9.0/10

Wonderful

(1,300 reviews)

"The staff is friendly, the room was clean, and the breakfast was wonderful. Would stay there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Steven

CA $142

CA $163 total

includes taxes & fees

Feb 13 - Feb 14

[](https://www.expedia.ca/San-Francisco-Hotels-Best-Western-Coyote-Point-Inn.h880752.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/f5fef020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/42a1392c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/c342f829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/a537213b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aloft San Francisco Airport

[](https://www.expedia.ca/San-Francisco-Hotels-Aloft-San-Francisco-Airport.h13950.Hotel-Information)

6.9 km from Downtown South San Francisco

9.0/10

Wonderful

(2,254 reviews)

"Great place! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jon

CA $155

CA $178 total

includes taxes & fees

Feb 21 - Feb 22

[](https://www.expedia.ca/San-Francisco-Hotels-Aloft-San-Francisco-Airport.h13950.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/487/128a46e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/10000/500/487/111baa3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/500/487/81433b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/487/f6105ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton San Francisco South Airport Blvd

[](https://www.expedia.ca/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-South-Airport-Blvd.h487.Hotel-Information)

1.5 km from Downtown South San Francisco

8.4/10

Very good

(2,113 reviews)

"Clean rooms and good location! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Khant

CA $141

CA $167 total

includes taxes & fees

Feb 21 - Feb 22

[](https://www.expedia.ca/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-South-Airport-Blvd.h487.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/d9a28cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/6a4c1f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/c37b3c13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/e6503d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Zoe Fisherman's Wharf

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zoe-Fishermans-Wharf.h3552.Hotel-Information)

16.6 km from Downtown South San Francisco

9.2/10

Wonderful

(1,709 reviews)

"Great location, wonderful staff, and nice hotel. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nivia

CA $154

CA $240 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zoe-Fishermans-Wharf.h3552.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/7d66de20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/7d3dc3be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/w5614h3742x0y0-0021dd27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/cf567017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express and Suites Fisherman's Wharf by IHG

[](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Express-And-Suites-Fishermans-Wharf.h578899.Hotel-Information)

16.7 km from Downtown South San Francisco

9.0/10

Wonderful

(2,291 reviews)

"Beautiful room with a nice view of Alcatraz. Will definitely stay here again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

kevin

CA $179

CA $255 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Express-And-Suites-Fishermans-Wharf.h578899.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/85c9e6e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/8d3345b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/bd21a30e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/7eae4e02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton San Francisco Airport Bayfront

[](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Airport-Bayfront.h12345.Hotel-Information)

9.9 km from Downtown South San Francisco

8.6/10

Excellent

(2,915 reviews)

"The room and breakfast was perfect "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daniel

CA $145

CA $164 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Airport-Bayfront.h12345.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/f6c9f16f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/339fb7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/26b347aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/d25eaf84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Dylan at SFO

[](https://www.expedia.ca/San-Francisco-Hotels-The-Dylan-At-SFO.h24251.Hotel-Information)

7.1 km from Downtown South San Francisco

9.2/10

Wonderful

(1,828 reviews)

"great hotel, well designed, comfortable beds, easy access to the bart and aiport"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alan

CA $141

CA $169 total

includes taxes & fees

Feb 14 - Feb 15

[](https://www.expedia.ca/San-Francisco-Hotels-The-Dylan-At-SFO.h24251.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/1000000/10000/900/828/efc155d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/1000000/10000/900/828/550e44fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/828/8f88044a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/900/828/6c45dc3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton San Francisco Airport

[](https://www.expedia.ca/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-Airport.h828.Hotel-Information)

9.3 km from Downtown South San Francisco

8.6/10

Excellent

(1,455 reviews)

"Great hotel "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jill

CA $138

CA $157 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-Airport.h828.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/173b8dfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/7bc06dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/19abbe84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/a3393d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Zephyr San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information)

16.8 km from Downtown South San Francisco

8.6/10

Excellent

(2,423 reviews)

"Great location on the wharf, with many restaurants, and activities in the area."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Frank

CA $163

CA $248 total

includes taxes & fees

Feb 12 - Feb 13

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/d2ce10c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/17458474.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom (Corporate) | Living area](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/57a12208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Chancellor Hotel on Union Square

[](https://www.expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information)

14.7 km from Downtown South San Francisco

9.4/10

Exceptional

(3,186 reviews)

"I loved this stay! Extremely friendly staff and amazing rooms"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hajar

CA $134

CA $158 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21&regionId=553248635976481411&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. 

- Union Square
- Fisherman's Wharf
- Downtown San Francisco
- South of Market
- Nob Hill

![Union Square San Francisco a shop-aholic dream; Shutterstock ID 3603152](https://images.trvl-media.com/place/800129/ff54c8de-2306-4c3c-95db-959bb81edbd6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Union Square featuring a city, a monument and a square or plaza](https://images.trvl-media.com/place/800129/f4f0b994-d3bb-4e9e-b7b4-bab93b97719e.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Union Square showing skyline, a city and a square or plaza](https://images.trvl-media.com/place/800129/8dc3ff9c-68b2-4d8a-b4db-bc59acf8c092.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Colorful heart sculpture in Union Square surrounded by palm trees in San Francisco](https://images.trvl-media.com/place/800129/eea963aa-6a72-406f-a176-07dd5378c21e.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Union Square featuring a city, a square or plaza and shopping](https://images.trvl-media.com/place/800129/b173ebfb-8ede-4559-b201-65fceb05bd4c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=800129)

![Union Square map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:owseFngdjV_H%7BeAzRuBna%40%7Ej%40qPdCn%40pIwDv%40n%40tGaXjD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=vbtXVjtvbbFJoglIicZiXTBOs3E=)

### Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=800129)

![Fisherman\'s Wharf which includes street scenes as well as a small group of people](https://images.trvl-media.com/place/800128/41ac8fc2-48eb-4cd6-9eda-e4bbe11ef364.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Fisherman\'s Wharf which includes marine life and a marina as well as a small group of people](https://images.trvl-media.com/place/800128/5e25998c-beb6-47e6-b787-e18d4ca82ba6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Pier 39 featuring signage](https://images.trvl-media.com/place/502576/7c85a1e7-6dcc-4eab-955a-51250d18dcf6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Fisherman\'s Wharf featuring marine life and a marina](https://images.trvl-media.com/place/800128/4cf27aae-2ccd-4cf3-9478-8dda6e43e50e.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Fisherman\'s Wharf featuring rides and street scenes as well as a small group of people](https://images.trvl-media.com/place/800128/00fafade-cf0b-4fde-be03-2f2a469fa65f.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=800128)

![Fisherman's Wharf map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mrweFnpfjVaIcEiDic%40wAal%40xF_c%40bZoH%60N%7CwBeMnBaIpEsF%7E%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=cSLnJ-bErQxSUv6GQKloGDHAW70=)

### Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=800128)

![Downtown San Francisco featuring railway items](https://images.trvl-media.com/place/6151902/22bc1dd6-2f5f-4efc-bbac-d6cb6e07fc99.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

!["Downtown cityscape of San Francisco California, USA with the painted ladies house"](https://images.trvl-media.com/place/6151902/91cda6a7-7e43-43ba-a209-abfb4d647bf4.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Downtown San Francisco featuring railway items and a city](https://images.trvl-media.com/place/6151902/a3b7f851-bd65-4332-9116-bb43d453ea59.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![San Francisco Museum of Modern Art showing a city](https://images.trvl-media.com/place/6063201/0da6e0d0-bbf0-4a77-b3d9-7c04c6bc6bf3.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Downtown San Francisco](https://images.trvl-media.com/place/6151902/342aec39-50a1-4209-bc0a-ec595d5dfa9c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6151902)

![Downtown San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:m%7EteFvzejViZadFhsAmj%40%60lBaHdLhWlEviCoQtFoGdcByHdFwR%7BUc%60ChY&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=gvmSEImu4_lfi0gTpvxWcEmihx8=)

### Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6151902)

![South of Market showing skyline, a city and city views](https://images.trvl-media.com/place/160166/f4a16719-d8ac-4494-aeaa-4bbf3b1bebfc.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![South of Market showing a fountain, city views and a city](https://images.trvl-media.com/place/160166/4febb5b3-dfb4-478e-9be4-4486204cf61d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![South of Market featuring city views and a city](https://images.trvl-media.com/place/160166/d978ce28-57da-48eb-ab6c-926b6c394bce.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![South of Market showing a garden, a church or cathedral and a city](https://images.trvl-media.com/place/160166/801d6438-74c4-4a46-8d17-fba0d62cda4c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Public Bicycle rental located throughout  downtown San Francisco are conveniently located and reasonably priced. Current prices are $9 per day and 24 for three days for unlimited rides.](https://images.trvl-media.com/place/160166/b4e80b87-2fa1-4e85-a77e-6da390bd6bb9.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

Photo by Majid Shaheen

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=160166)

![South of Market map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eipeF%7CxejVcaDsjEjv%40gt%40ffCuYvGdhDsKvBsD%7CF%7DBz%5BoCx%7C%40_E%7EGqC%7EA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ffiqKO1x2yhUpPKU2D52Jx63lg4=)

### South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=160166)

![Nob Hill which includes street scenes](https://images.trvl-media.com/place/138629/f2c721e1-9634-471e-8501-e4a78e5e1d3f.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill showing street scenes](https://images.trvl-media.com/place/138629/4d1d1751-0c33-4c82-a803-46c950f237a2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill which includes street scenes and a city](https://images.trvl-media.com/place/138629/31bdc0e9-2bb7-4c93-a7c5-29f0334ae514.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill which includes a city](https://images.trvl-media.com/place/138629/a98fecf7-7efc-443f-b58d-5ae2a2bd5c14.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill which includes street scenes](https://images.trvl-media.com/place/6162235/ac4bf5fc-a04a-4c5e-987c-405af72fc275.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=138629)

![Nob Hill map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:q%7EteFvxejVmIopAll%40cHnIppAol%40%60H&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Skcsr6ZgxKZlWMjutOt189xwFug=)

### Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=138629)

## Top Downtown South San Francisco Hotel Reviews

![Club Quarters Hotel in San Francisco](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg)

### Club Quarters Hotel in San Francisco

10/10 Excellent

"Clean room. Nice staff!"

[](https://expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information)

![Holiday Inn Golden Gateway by IHG](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg)

### Holiday Inn Golden Gateway by IHG

10/10 Excellent

"Clean room "

[](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information)

![Chancellor Hotel on Union Square](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c_y.jpg)

### Chancellor Hotel on Union Square

10/10 Excellent

"Great location "

[](https://expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information)

![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg)

### Handlery Union Square Hotel

10/10 Excellent

"Friendly staff great location "

[](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information)

![Bay Landing San Francisco Airport Hotel](https://images.trvl-media.com/lodging/2000000/1120000/1110800/1110785/0c231d9b_y.jpg)

### Bay Landing San Francisco Airport Hotel

10/10 Excellent

"Room was very clean and comfortable. Bed was extra comfortable as staff went above and beyond to make sure I was happy."

[](https://expedia.ca/San-Francisco-Hotels-Bay-Landing-San-Francisco-Airport-Hotel.h1110785.Hotel-Information)

![Fairmont San Francisco](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg)

### Fairmont San Francisco

10/10 Excellent

"Nice residence and nice place."

[](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information)

![Hilton San Francisco Financial District](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg)

### Hilton San Francisco Financial District

10/10 Excellent

"Savvy, clean, sleek in a very clean China town. I love the cars a aialbe to pick you up and drop off as part of the guest services. The breakfast was not buffet style but still covered side orders of fruit and drinks. It was a good deal to have it connected with your room purchase. The view was breathe taking--- clean, spacious and wonderful. "

[](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information)

![DoubleTree by Hilton Hotel Berkeley Marina](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg)

### DoubleTree by Hilton Hotel Berkeley Marina

10/10 Excellent

"Was clean and comfortable. "

[](https://expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information)

![Hyatt Centric Fisherman's Wharf San Francisco](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg)

### Hyatt Centric Fisherman's Wharf San Francisco

10/10 Excellent

"The room was so comfortable and clean! The beds are very soft and cozy. The front desk staff is super friendly. Location is amazing to walk to pier 39 and access lots of all that is San Francisco!"

[](https://expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information)

## Frequently asked questions

### What's it like in Downtown South San Francisco?

### What's a favorite place to stay in Downtown South San Francisco?

### How many hotels will I find in the Downtown South San Francisco area?

### If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

### What can I see and do in this South San Francisco neighborhood?

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- [Flights to San Francisco ](https://www.expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)
- [Flights to South San Francisco ](https://www.expedia.ca/Cheap-Flights-To-South-San-Francisco.d6773.Travel-Guide-Flights)
- [Flights from Los Angeles (LAX) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/lax/sfo/los-angeles-to-san-francisco)
- [Flights from Edmonton (YEG) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yeg/sfo/edmonton-to-san-francisco)
- [Flights from Montreal (YUL) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yul/sfo/montreal-to-san-francisco)
- [Flights from Vancouver (YVR) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yvr/sfo/vancouver-to-san-francisco)
- [Flights from Calgary (YYC) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yyc/sfo/calgary-to-san-francisco)
- [Flights from Toronto (YYZ) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yyz/sfo/toronto-to-san-francisco)

- [Visit Paradise Valley ](https://www.expedia.ca/San-Francisco-Paradise-Valley.dx553248635976473811)
- [South San Francisco Vacations ](https://www.expedia.ca/South-San-Francisco.d6773.Destination-Travel-Guides)
- [Visit South San Francisco ](https://www.expedia.ca/South-San-Francisco.dx6773)

- [Rental cars San Francisco Intl. airport ](https://www.expedia.ca/Car-Rentals-In-San-Francisco-Intl.d5195347.Car-Rental-Guide)
- [Car rental South San Francisco ](https://www.expedia.ca/Car-Rentals-In-South-San-Francisco.d6773.Car-Rental-Guide)
- [Enterprise Rental Cars in South San Francisco ](https://www.expedia.ca/Enterprise-Car-Rentals-In-South-San-Francisco.d6773-c15.Car-Rental-Guide-Suppliers)
- [Hertz Rental Cars in South San Francisco ](https://www.expedia.ca/Hertz-Car-Rentals-In-South-San-Francisco.d6773-c40.Car-Rental-Guide-Suppliers)

- [South San Francisco Vacation Rentals ](https://www.expedia.ca/South-San-Francisco-Vacation-Rentals.d6773.Travel-Guide-VacationRentals)

- [Things to do in South San Francisco ](https://www.expedia.ca/Things-To-Do-In-South-San-Francisco.d6773.Travel-Guide-Activities)

- [Book Hotels in Downtown South San Francisco on Expedia.com ](https://www.expedia.com/Downtown-South-San-Francisco-San-Francisco-Hotels.0-n553248635976481411-0.Travel-Guide-Filter-Hotels)