Title: 10 Best Hotels in Downtown South San Francisco, San Francisco for 2025 | Expedia.ca [Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Downtown South San Francisco Car Rentals](https://expedia.ca/Car-Rentals-In-Downtown-South-San-Francisco.d553248635976481411.Car-Rental-Guide)[Downtown South San Francisco Vacations](https://expedia.ca/Downtown-South-San-Francisco.d553248635976481411.Destination-Travel-Guides) ![Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015](https://images.trvl-media.com/place/553248635976481411/4dd74f8a-dfcd-4623-817e-767c96ff0c5c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Downtown South San Francisco, San Francisco ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Downtown South San Francisco Spa [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=SPA_ON_SITE) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=HOT_TUB) Pool [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=POOL) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&travelerType=family_friendly) Ocean view [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=OCEAN_VIEW) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=PETS) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&lodging=APARTMENT) Condo [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&lodging=CONDO) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&lodging=COTTAGE) ## Check prices for these dates Tonight [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-10-30&endDate=2025-10-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-10-31&endDate=2025-11-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Downtown South San Francisco hotels and places to stay ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/5d196618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/4becccdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/f426e9e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Multiple Beds, Accessible, Non Smoking (Mobility/Hearing Impaired Accessible)](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/6c7a44bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Francisco Airport N Downtown South San Francisco 8.0/10 Very good (2036) "The staff at check in and check out were VERY friendly!! I appreciated that it was close to the airport and a Denny’s for lunch!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $141 CA $166 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/779a738f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/72b32b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/466a0c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/8dc758c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Airport Inn Downtown South San Francisco 8.8/10 Excellent (967) "I was surprised by how friendly the front desk guy was when I checked in after midnight, and also by how clean the room was, for the price I would say this is unbeatable for the area, I will be back." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Todd CA $130 CA $153 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/San-Francisco-Hotels-Airport-Inn.h11974670.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/aeecf8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/9b3dc53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/b9912bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/72fd4af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn By The SFO Downtown South San Francisco 7.8/10 Good (1001) "Room is spacious" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) leo [](https://www.expedia.ca/San-Francisco-Hotels-Inn-By-The-SFO.h1139289.Hotel-Information) ![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/48a324c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/a007dfc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/60ad2a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/d205a5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Miller Apartments Downtown South San Francisco 7.4/10 Good (15) "Ty" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mariah CA $87 CA $208 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/San-Francisco-Hotels-Miller-Apartments.h91116819.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/b406d764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/w5614h3742x0y0-0021dd27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/927fa680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/7d66de20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express and Suites Fisherman's Wharf by IHG 16.6 km from Downtown South San Francisco 9.0/10 Wonderful (2206) "Perfect stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $192 CA $268 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Express-And-Suites-Fishermans-Wharf.h578899.Hotel-Information) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1040000/1038100/1038086/b2c792a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1040000/1038100/1038086/f593cfd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1040000/1038100/1038086/9e90a383.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/2000000/1040000/1038100/1038086/6f39558c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harbor View Inn 17.7 km from Downtown South San Francisco 9.0/10 Wonderful (594) "This is a good well kept motel. The rooms are a good value. I would stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $165 CA $194 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Half-Moon-Bay-Hotels-Harbor-View-Inn.h1038086.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1154600/1154559/a6d4d3b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1154600/1154559/7e38cd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/2000000/1160000/1154600/1154559/e2af1c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1160000/1154600/1154559/b4f5291a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel North Beach 15.6 km from Downtown South San Francisco 7.0/10 Good (1003) "Decent rooms at a decent price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Louis CA $76 CA $89 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-North-Beach.h1154559.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/9f22ad54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Loft, 1 Bedroom, Balcony, Golf View](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/1d228ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/0992f574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/a404f6d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Half Moon Bay Lodge 24.9 km from Downtown South San Francisco 9.0/10 Wonderful (1036) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yelena CA $170 CA $200 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Half-Moon-Bay-Hotels-Half-Moon-Bay-Lodge.h11624.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/22520ee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/ace9cc04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/db29a2e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Centric Fisherman's Wharf San Francisco 16.6 km from Downtown South San Francisco 8.6/10 Excellent (1459) "very nice hotel and staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Margarita CA $165 CA $251 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/0bf5bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/67096996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/c37460ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/3fd8b468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Caza Fisherman's Wharf 16.7 km from Downtown South San Francisco 9.0/10 Wonderful (3820) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $182 CA $278 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/e62e0c90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/75f20517.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/b020c7fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Fisherman's Wharf 16.7 km from Downtown South San Francisco 9.0/10 Wonderful (7001) "Wonderful stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ernestina CA $152 CA $237 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/818bb89d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/9dd6fb90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Queen Room](https://images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/d9813769.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/7ed3ce17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### FOUND Hotel Carlton, Nob Hill 14.6 km from Downtown South San Francisco 8.6/10 Excellent (996) "Very nice condition of hotel for the price. Updated interior and very friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emma CA $91 CA $108 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/San-Francisco-Hotels-FOUND-Hotel-San-Francisco-Carlton.h103126565.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/70000/60300/60226/2392a014.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/70000/60300/60226/91c59b83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/70000/60300/60226/fc8303ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/60300/60226/5452c586.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Tiburon 24.5 km from Downtown South San Francisco 8.8/10 Excellent (1026) "We enjoyed our stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Xiaoyu CA $254 CA $324 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Tiburon-Hotels-The-Lodge-At-Tiburon.h60226.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/095a2e83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/b9e253e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/5beb890e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/b0813be9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marina Inn on San Francisco Bay 20.6 km from Downtown South San Francisco 8.6/10 Excellent (2200) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dixon CA $146 CA $166 total includes taxes & fees Nov 18 - Nov 19 [](https://www.expedia.ca/Oakland-Hotels-The-Marina-Inn-On-San-Francisco-Bay.h51116.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26500/26500/7b888e27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26500/26500/ccdc9b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/26500/26500/386569df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26500/26500/4e19d797.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency San Francisco Airport 8.4 km from Downtown South San Francisco 8.8/10 Excellent (1327) "Great place to stay near the airport shuttle is very on time " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gurtaij CA $188 CA $253 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Regency-San-Francisco-Airport.h26500.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/530000/522600/522505/03e99609.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/530000/522600/522505/0e6886b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/1000000/530000/522600/522505/48e07708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/530000/522600/522505/a5ec2a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Focus SFO The East Side, 1.3 km from Downtown South San Francisco 7.6/10 Good (1480) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Walter CA $112 CA $132 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Focus-SFO.h522505.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/550000/548000/547988/w3836h2556x4y4-feec9994.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/1000000/550000/548000/547988/w3836h2560x4y0-6639a7a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served](https://images.trvl-media.com/lodging/1000000/550000/548000/547988/w3837h2557x3y3-420d1afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Bay View](https://images.trvl-media.com/lodging/1000000/550000/548000/547988/w3837h2557x3y3-515ac187.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HYATT house Emeryville/San Francisco Bay Area 23 km from Downtown South San Francisco 9.0/10 Wonderful (1171) "My stay was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jermyla CA $201 CA $225 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Oakland-Hotels-HYATT-House-EmeryvilleSan-Francisco-Bay-Area.h547988.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5800/5798/fee85a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/5800/5798/767c7710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/5800/5798/b1137dc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/5800/5798/fc92bfae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SFO El Rancho Inn SureStay Collection by Best Western 5.7 km from Downtown South San Francisco 8.4/10 Very good (2930) "Always a great stay when i'm here. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Afele CA $159 CA $184 total includes taxes & fees Nov 8 - Nov 9 [](https://www.expedia.ca/San-Francisco-Hotels-SFO-Airport-Hotel.h5798.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/060ec935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/d655bded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/1ac737fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cafe](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/3960290f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Pickwick Hotel 14.1 km from Downtown South San Francisco 8.0/10 Very good (1008) "Nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Orlando CA $122 CA $143 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/San-Francisco-Hotels-The-Pickwick-Hotel.h11793.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/47630b7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/26b347aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/da78accc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/f6c9f16f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Dylan at SFO 7.1 km from Downtown South San Francisco 9.2/10 Wonderful (1778) "Nice place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cindy CA $148 CA $176 total includes taxes & fees Nov 28 - Nov 29 [](https://www.expedia.ca/San-Francisco-Hotels-The-Dylan-At-SFO.h24251.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15®ionId=553248635976481411&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Hotels in Downtown South San Francisco with a pool ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/5d196618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/4becccdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/f426e9e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Multiple Beds, Accessible, Non Smoking (Mobility/Hearing Impaired Accessible)](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/6c7a44bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Francisco Airport N Downtown South San Francisco - Pool 8.0/10 Very good (2036) CA $141 CA $166 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-09&endDate=2025-11-10&selected=9329&PinnedHotelID=9329&HadPinnedHotel=true®ionId=553248635976481411&adults=2&amenities=POOL&openPlayBack=true) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/e62e0c90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/75f20517.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/b020c7fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Fisherman's Wharf 16.7 km from Downtown South San Francisco - Pool 9.0/10 Wonderful (7001) CA $152 CA $237 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-30&endDate=2025-12-01&selected=24625&PinnedHotelID=24625&HadPinnedHotel=true®ionId=553248635976481411&adults=2&amenities=POOL&openPlayBack=true) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12600/12539/e42fcc88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom | Living area](https://images.trvl-media.com/lodging/1000000/20000/12600/12539/50dd0fbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 King Bed (Residence 55) | Living area](https://images.trvl-media.com/lodging/1000000/20000/12600/12539/8ff83d1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/1000000/20000/12600/12539/c304c2cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Parc 55 San Francisco - A Hilton Hotel 14.3 km from Downtown South San Francisco - Pool 8.6/10 Excellent (1445) CA $170 CA $261 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-21&endDate=2025-11-22&selected=12539&PinnedHotelID=12539&HadPinnedHotel=true®ionId=553248635976481411&adults=2&amenities=POOL&openPlayBack=true) ![Outdoor pool, open 9:00 AM to 7:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/3372ea26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/1b544d3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/d650815d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Golden Gateway by IHG 14.8 km from Downtown South San Francisco - Pool 9.0/10 Wonderful (4746) CA $172 CA $202 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-23&endDate=2025-11-24&selected=10538&PinnedHotelID=10538&HadPinnedHotel=true®ionId=553248635976481411&adults=2&amenities=POOL&openPlayBack=true) ![Exterior](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/0bf5bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/67096996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/c37460ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/3fd8b468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Caza Fisherman's Wharf 16.7 km from Downtown South San Francisco - Pool 9.0/10 Wonderful (3820) CA $182 CA $278 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-01&endDate=2025-12-02&selected=38249309&PinnedHotelID=38249309&HadPinnedHotel=true®ionId=553248635976481411&adults=2&amenities=POOL&openPlayBack=true) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/22520ee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/ace9cc04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/db29a2e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Centric Fisherman's Wharf San Francisco 16.6 km from Downtown South San Francisco - Pool 8.6/10 Excellent (1459) CA $165 CA $251 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-23&endDate=2025-11-24&selected=22500&PinnedHotelID=22500&HadPinnedHotel=true®ionId=553248635976481411&adults=2&amenities=POOL&openPlayBack=true) ![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/5800bbe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/7856c00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/b8f68e45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/d2b20643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental San Francisco by IHG 13.9 km from Downtown South San Francisco - Pool 9.2/10 Wonderful (1002) CA $216 CA $312 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-07&endDate=2025-11-08&selected=1766605&PinnedHotelID=1766605&HadPinnedHotel=true®ionId=553248635976481411&adults=2&amenities=POOL&openPlayBack=true) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/6c2cdc12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/3daecce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/6a2ba7f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed, Accessible](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/w1781h1201x19y0-3696f576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Nikko San Francisco 14.3 km from Downtown South San Francisco - Pool 9.4/10 Exceptional (2576) CA $227 CA $331 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-07&endDate=2025-11-08&selected=23406&PinnedHotelID=23406&HadPinnedHotel=true®ionId=553248635976481411&adults=2&amenities=POOL&openPlayBack=true) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28600/28502/336a0345.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/28600/28502/8f2a7422.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/28600/28502/3a82d444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28600/28502/ea6d435b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza San Francisco Airport by IHG 8.9 km from Downtown South San Francisco - Pool 7.8/10 Good (2348) CA $114 CA $130 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&selected=28502&PinnedHotelID=28502&HadPinnedHotel=true®ionId=553248635976481411&adults=2&amenities=POOL&openPlayBack=true) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/63a5d8bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool, open 8 AM to 8 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/4fd95a3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/18d49d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Handlery Union Square Hotel 14.5 km from Downtown South San Francisco - Pool 8.8/10 Excellent (2839) CA $191 CA $225 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02&selected=6666&PinnedHotelID=6666&HadPinnedHotel=true®ionId=553248635976481411&adults=2&amenities=POOL&openPlayBack=true) [See more properties](https://www.expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15®ionId=553248635976481411&adults=2&sort=RECOMMENDED&amenities=POOL&openPlayBack=true) ## Top guest rated hotels in Downtown South San Francisco ![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/779a738f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/72b32b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/466a0c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/8dc758c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Airport Inn Downtown South San Francisco 8.8/10 Excellent (967) CA $130 CA $153 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-01&endDate=2025-12-02&selected=11974670&PinnedHotelID=11974670&HadPinnedHotel=true®ionId=553248635976481411&adults=2&guestRating=35&openPlayBack=true) ![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/48a324c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/a007dfc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/60ad2a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/d205a5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Miller Apartments Downtown South San Francisco 7.4/10 Good (15) CA $87 CA $208 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02&selected=91116819&PinnedHotelID=91116819&HadPinnedHotel=true®ionId=553248635976481411&adults=2&guestRating=35&openPlayBack=true) ![Lobby](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/aeecf8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/9b3dc53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/b9912bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/72fd4af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn By The SFO Downtown South San Francisco 7.8/10 Good (1001) [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15&selected=1139289&PinnedHotelID=1139289&HadPinnedHotel=true®ionId=553248635976481411&adults=2&guestRating=35&openPlayBack=true) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/500/491/5e565895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/500/491/fd911583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/500/491/c9a2355d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/500/491/76fc74a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency San Francisco Downtown SOMA 14.5 km from Downtown South San Francisco 9.4/10 Exceptional (1294) CA $202 CA $294 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&selected=491&PinnedHotelID=491&HadPinnedHotel=true®ionId=553248635976481411&adults=2&guestRating=35&openPlayBack=true) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/15f08daf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/7d695984.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/4c4de4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Quarters Hotel in San Francisco 15.4 km from Downtown South San Francisco 8.8/10 Excellent (2707) CA $136 CA $160 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-23&endDate=2025-11-24&selected=912982&PinnedHotelID=912982&HadPinnedHotel=true®ionId=553248635976481411&adults=2&guestRating=35&openPlayBack=true) ![Interior](https://images.trvl-media.com/lodging/1000000/440000/438200/438136/7fe55669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/440000/438200/438136/511e67f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/438200/438136/dfcb3ab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/440000/438200/438136/42403dce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Shattuck Plaza 27 km from Downtown South San Francisco 8.8/10 Excellent (1041) CA $279 CA $321 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16&selected=438136&PinnedHotelID=438136&HadPinnedHotel=true®ionId=553248635976481411&adults=2&guestRating=35&openPlayBack=true) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/21cb8d87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/fcb07f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/c72c1799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/e6503d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zoe Fisherman's Wharf 16.7 km from Downtown South San Francisco 9.2/10 Wonderful (1539) CA $157 CA $245 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-23&endDate=2025-11-24&selected=3552&PinnedHotelID=3552&HadPinnedHotel=true®ionId=553248635976481411&adults=2&guestRating=35&openPlayBack=true) ![Room, 1 King Bed | City view](https://images.trvl-media.com/lodging/70000000/69560000/69551600/69551553/755268ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/70000000/69560000/69551600/69551553/5d84cf8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/70000000/69560000/69551600/69551553/w6657h6127x0y0-83c716df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (USD 22 per person)](https://images.trvl-media.com/lodging/70000000/69560000/69551600/69551553/w4873h4411x3y0-aaac6833.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### citizenM San Francisco Union Square 14.4 km from Downtown South San Francisco 9.6/10 Exceptional (1407) CA $180 CA $212 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-23&endDate=2025-11-24&selected=69551553&PinnedHotelID=69551553&HadPinnedHotel=true®ionId=553248635976481411&adults=2&guestRating=35&openPlayBack=true) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26100/26015/16fca6fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/26100/26015/7bbcb937.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Refrigerator](https://images.trvl-media.com/lodging/1000000/30000/26100/26015/11890051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26100/26015/36febcdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cartwright Hotel - Union Square BW Premier Collection 14.7 km from Downtown South San Francisco 8.8/10 Excellent (1003) CA $124 CA $146 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-30&endDate=2025-12-01&selected=26015&PinnedHotelID=26015&HadPinnedHotel=true®ionId=553248635976481411&adults=2&guestRating=35&openPlayBack=true) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/095a2e83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/b9e253e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/5beb890e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/b0813be9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marina Inn on San Francisco Bay 20.6 km from Downtown South San Francisco 8.6/10 Excellent (2200) CA $146 CA $166 total includes taxes & fees Nov 18 - Nov 19 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19&selected=51116&PinnedHotelID=51116&HadPinnedHotel=true®ionId=553248635976481411&adults=2&guestRating=35&openPlayBack=true) [See more properties](https://www.expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15®ionId=553248635976481411&adults=2&sort=RECOMMENDED&guestRating=35&openPlayBack=true) ## Where to stay in Downtown South San Francisco Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. - Union Square - Fisherman's Wharf - Downtown San Francisco - South of Market - Nob Hill ![Union Square featuring a city and a skyscraper](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22611-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Union Square featuring a city, street scenes and signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173736-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Union Square featuring a city, a monument and a square or plaza](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173470-Northern-California.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Union Square showing street scenes and a city as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/67000/67250-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Union Square showing street scenes, a city and signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173732-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=800129) ![Union Square map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:owseFngdjV_H%7BeAzRuBna%40%7Ej%40qPdCn%40pIwDv%40n%40tGaXjD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=vbtXVjtvbbFJoglIicZiXTBOs3E=) ### Union Square Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems. [See properties](https://www.expedia.ca/Hotel-Search?regionId=800129) ![Fisherman\'s Wharf featuring a bay or harbour](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/240000/240986-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/548000/548532-fishermans-wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Fisherman\'s Wharf which includes a bay or harbour](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173418-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Fisherman\'s Wharf which includes a fountain](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/240000/240993-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173428-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=800128) ![Fisherman's Wharf map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mrweFnpfjVaIcEiDic%40wAal%40xF_c%40bZoH%60N%7CwBeMnBaIpEsF%7E%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=cSLnJ-bErQxSUv6GQKloGDHAW70=) ### Fisherman's Wharf Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access. [See properties](https://www.expedia.ca/Hotel-Search?regionId=800128) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476363-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476367-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476362-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476359-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476366-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6151902) ![Downtown San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:m%7EteFvzejViZadFhsAmj%40%60lBaHdLhWlEviCoQtFoGdcByHdFwR%7BUc%60ChY&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=gvmSEImu4_lfi0gTpvxWcEmihx8=) ### Downtown San Francisco Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6151902) ![South of Market showing skyline, a city and city views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173326-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![South of Market showing a fountain, city views and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173924-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![South of Market featuring a city, a skyscraper and central business district](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173938-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![South of Market featuring skyline, city views and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173935-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![South of Market featuring city views and a city as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173937-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=160166) ![South of Market map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eipeF%7CxejVcaDsjEjv%40gt%40ffCuYvGdhDsKvBsD%7CF%7DBz%5BoCx%7C%40_E%7EGqC%7EA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ffiqKO1x2yhUpPKU2D52Jx63lg4=) ### South of Market From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods. [See properties](https://www.expedia.ca/Hotel-Search?regionId=160166) ![Nob Hill featuring street scenes and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173402-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Nob Hill which includes street scenes and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173400-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Nob Hill which includes street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173393-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Nob Hill which includes street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173395-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Nob Hill featuring street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173391-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=138629) ![Nob Hill map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:q%7EteFvxejVmIopAll%40cHnIppAol%40%60H&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Skcsr6ZgxKZlWMjutOt189xwFug=) ### Nob Hill Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history. [See properties](https://www.expedia.ca/Hotel-Search?regionId=138629) ## Top Downtown South San Francisco Hotel Reviews ![DoubleTree by Hilton Hotel Berkeley Marina](//images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg) ### DoubleTree by Hilton Hotel Berkeley Marina 10/10 Excellent "Perfect " [](https://expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information) ![Hotel Riu Plaza Fisherman's Wharf](//images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg) ### Hotel Riu Plaza Fisherman's Wharf 10/10 Excellent "Everything was nice, clean, and price friendly." [](https://expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Fairmont San Francisco](//images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg) ### Fairmont San Francisco 10/10 Excellent "This was a memory of a previous stay here 25 years ago. Still one of the best hotels in San Francisco. We Waymo'd and used the Cable Cars to get everywhere." [](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ![Handlery Union Square Hotel](//images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "Clean and spacious rooms." [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Hyatt Centric Fisherman's Wharf San Francisco](//images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg) ### Hyatt Centric Fisherman's Wharf San Francisco 10/10 Excellent "We enjoyed our stay very much. The room was nice, beds were comfortable, the pool was heated as stated and the hot tub was perfect. Pool has towels which we were happy to see!" [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) ![Holiday Inn Golden Gateway by IHG](//images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg) ### Holiday Inn Golden Gateway by IHG 10/10 Excellent "goos" [](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information) ![Hotel Caza Fisherman's Wharf](//images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/0bf5bd4c_y.jpg) ### Hotel Caza Fisherman's Wharf 10/10 Excellent "Centrally located, great restaurants near by. " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) ![Club Quarters Hotel in San Francisco](//images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg) ### Club Quarters Hotel in San Francisco 10/10 Excellent "My usual place to stay when I'm in the city." [](https://expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ![Hilton San Francisco Financial District](//images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg) ### Hilton San Francisco Financial District 10/10 Excellent "Great location and friendly staff!" [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ## Frequently asked questions ### What's it like in Downtown South San Francisco? > You'll be sure to have fun visiting South San Francisco's Downtown South San Francisco neighborhood. ### What's a favorite place to stay in Downtown South San Francisco? > Based on Expedia customer reviews, [La Quinta Inn & Suites by Wyndham San Francisco Airport N](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information) is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favorite options in the area include [Airport Inn](https://www.expedia.ca/San-Francisco-Hotels-Airport-Inn.h11974670.Hotel-Information) and [Inn By The SFO](https://www.expedia.ca/San-Francisco-Hotels-Inn-By-The-SFO.h1139289.Hotel-Information). ### How many hotels will I find in the Downtown South San Francisco area? > When you want to kick up your feet after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodations in Downtown South San Francisco. ### If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund? > Yes, the majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown South San Francisco. ### What can I see and do in this South San Francisco neighborhood? > See's Candies, Cinemark Century at Tanforan, and K1 Speed are just a few of the places to visit in and around Downtown South San Francisco. K1 Speed San Francisco and The Shops at Tanforan are also worth a visit when you're out sightseeing in South San Francisco. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [1 Star Hotels in Paradise Valley](https://www.expedia.ca/1Star-Paradise-Valley-San-Francisco-Hotels.s10-n553248635976473811-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Oyster Point](https://www.expedia.ca/5Star-Oyster-Point-San-Francisco-Hotels.s50-n553248635976007474-0.Travel-Guide-Filter-Hotels) - [Avalon Hotels](https://www.expedia.ca/Avalon-San-Francisco-Hotels.0-n553248635976479280-0.Travel-Guide-Filter-Hotels) - [Hotels near Bayfront Park](https://www.expedia.ca/Bayfront-Park-Hotels.0-l553248621579088854-0.Travel-Guide-Filter-Hotels) - [Bayshore Heights Hotels](https://www.expedia.ca/Bayshore-Heights-San-Francisco-Hotels.0-n553248635976471419-0.Travel-Guide-Filter-Hotels) - [Brisbane Hotels](https://www.expedia.ca/Brisbane-Hotels.d602634.Travel-Guide-Hotels) - 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